المؤلفون: Andrea Holla, Erik W. Martin, Thomas Dannenhoffer-Lafage, Kiersten M. Ruff, Sebastian L. B. König, Mark F. Nüesch, Aritra Chowdhury, John M. Louis, Andrea Soranno, Daniel Nettels, Rohit V. Pappu, Robert B. Best, Tanja Mittag, Benjamin Schuler

المصدر: JACS Au, Vol 4, Iss 12, Pp 4729-4743 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2691-3704

URL الوصول: https://doaj.org/article/700937265e6241439377813b2beabad1

المؤلفون: Annie Aniana, Nashaat T. Nashed, Rodolfo Ghirlando, Leighton Coates, Daniel W. Kneller, Andrey Kovalevsky, John M. Louis

المصدر: Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/cc30133938ec44e9a71f4b0649ccbb2c

المؤلفون: Nashaat T. Nashed, Daniel W. Kneller, Leighton Coates, Rodolfo Ghirlando, Annie Aniana, Andrey Kovalevsky, John M. Louis

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/1e9e8033fd684980a02f9f29673a1d18

المؤلفون: Daniel W. Kneller, Hui Li, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Mark A. Arnould, Colleen B. Jonsson, Surekha Surendranathan, Jyothi Parvathareddy, Matthew P. Blakeley, Leighton Coates, John M. Louis, Peter V. Bonnesen, Andrey Kovalevsky

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a34b92fdec104f1c9e1eb9363f0311ad

المؤلفون: Nashaat T. Nashed, Annie Aniana, Rodolfo Ghirlando, Sai Chaitanya Chiliveri, John M. Louis

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/613c4d7153af4acfb58e7dadb2dc7ff4

المؤلفون: Daniel W. Kneller, Qiu Zhang, Leighton Coates, John M. Louis, Andrey Kovalevsky

المصدر: IUCrJ, Vol 8, Iss 6, Pp 973-979 (2021)

مصطلحات موضوعية: sars-cov-2, 3cl protease, main protease, catalytic mechanism, c145a mutant, enzyme–substrate complex, room-temperature x-ray crystallography, Crystallography, QD901-999

وصف الملف: electronic resource

Relation: http://scripts.iucr.org/cgi-bin/paper?S2052252521010113; https://doaj.org/toc/2052-2525

URL الوصول: https://doaj.org/article/53704c447e1746098f45e3c77c49f7ca

المؤلفون: Janghyun Yoo, Jae-Yeol Kim, John M. Louis, Irina V. Gopich, Hoi Sung Chung

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/43303b5b95fe4c4c8636c35d24a12b28

المؤلفون: Mukesh Kumar, Kalyaneswar Mandal, Matthew P. Blakeley, Troy Wymore, Stephen B. H. Kent, John M. Louis, Amit Das, Andrey Kovalevsky

المصدر: ACS Omega, Vol 5, Iss 20, Pp 11605-11617 (2020)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/e4f2178b23464f3c8312a8998ffe950f

المؤلفون: Jevgenij A. Raskatov (1280973), Alejandro R. Foley (11256365), John M. Louis (237589), Wai-Ming Yau (1576471), Robert Tycko (1576465)

مصطلحات موضوعية: Biophysics, Biochemistry, Immunology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Racemic Mixture, electron microscopy, antiparallel β- sheets, antiparallel alignments, racemic mixtures, l molecules, β- sheets, homochiral counterparts, DFT calculations support, β oligomers, l-A β40 fibril structures, Solid-State NMR, NMR spectra, l-A β40 fibrils, fibril growth direction, amyloidogenic peptides, β- strand segments, l-A β40, β structures, NMR data, hydrogen bonds, 42- residue amyloid -β peptides

Relation: https://figshare.com/articles/journal_contribution/Constraints_on_the_Structure_of_Fibrils_Formed_by_a_Racemic_Mixture_of_Amyloid_Peptides_from_Solid-State_NMR_Electron_Microscopy_and_Theory/15144194

الاتاحة: https://doi.org/10.1021/jacs.1c06339.s001

المؤلفون: Daniel W. Kneller (10357652), Hui Li (32376), Stephanie Galanie (3470420), Gwyndalyn Phillips (10357655), Audrey Labbé (11614634), Kevin L. Weiss (2181330), Qiu Zhang (239441), Mark A. Arnould (10925210), Austin Clyde (11614637), Heng Ma (240045), Arvind Ramanathan (198127), Colleen B. Jonsson (132961), Martha S. Head (2466190), Leighton Coates (1274958), John M. Louis (237589), Peter V. Bonnesen (2038771), Andrey Kovalevsky (1296192)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, positively charged linker, maintaining correct geometry, established drug target, molecule antivirals specific, assisted structure analysis, ray structures demonstrated, pro , enzyme inhibition assays, binding subsites s1, 2 main protease, subsites s1, vitro <, protease inhibitors, neutron structure, molecule building, inhibitor binding, enzyme ’, virtual reality, protonation states, protonated his163, p1 group, noncovalent compounds

Relation: https://figshare.com/articles/journal_contribution/Structural_Electronic_and_Electrostatic_Determinants_for_Inhibitor_Binding_to_Subsites_S1_and_S2_in_SARS-CoV_2_Main_Protease/16891112

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01475.s001

المؤلفون: Myungwoon Lee, Wai-Ming Yau, John M. Louis, Robert Tycko

المصدر: Proceedings of the National Academy of Sciences. 120

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::155ba757a91a0b9c1095f2b0cfb48358
https://doi.org/10.1073/pnas.2218831120

المؤلفون: Leighton Coates, Daniel W. Kneller, Qiu Zhang, Andrey Kovalevsky, John M. Louis

المصدر: IUCrJ, Vol 8, Iss 6, Pp 973-979 (2021)
IUCrJ

مصطلحات موضوعية: Stereochemistry, medicine.medical_treatment, In silico, Crystal structure, catalytic mechanism, medicine.disease_cause, Biochemistry, c145a mutant, 3cl protease, medicine, General Materials Science, Enzyme substrate complex, Mutation, Protease, Crystallography, Chemistry, enzyme–substrate complex, room-temperature x-ray crystallography, Substrate (chemistry), General Chemistry, Condensed Matter Physics, Cysteine protease, Research Papers, sars-cov-2, main protease, QD901-999, X-ray crystallography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcbe27bc197b3c173fd9644f287a292
http://scripts.iucr.org/cgi-bin/paper?S2052252521010113

المؤلفون: John M. Louis, Alejandro R. Foley, Jevgenij A. Raskatov, Robert Tycko, Wai-Ming Yau

المصدر: J Am Chem Soc

مصطلحات موضوعية: Amyloid, Amyloid beta-Peptides, Chemistry, Hydrogen bond, Supramolecular chemistry, macromolecular substances, General Chemistry, Fibril, Antiparallel (biochemistry), Biochemistry, Article, Catalysis, NMR spectra database, Microscopy, Electron, Crystallography, Colloid and Surface Chemistry, Solid-state nuclear magnetic resonance, Humans, Racemic mixture, Molecule, Nuclear Magnetic Resonance, Biomolecular, Density Functional Theory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffb3089b07a127fd176f75ea218ec89
https://doi.org/10.1021/jacs.1c06339

المؤلفون: Belhu B. Metaferia, Julia Harper, John M. Louis, William A. Eaton, Kristen E. Glass, Eric R. Henry

المصدر: Biophysical Journal. 120:2543-2551

مصطلحات موضوعية: Allosteric regulation, Biophysics, chemistry.chemical_element, Anemia, Sickle Cell, Plasma protein binding, Oxygen, Dissociation (chemistry), Hemoglobins, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, medicine, Humans, 030304 developmental biology, 0303 health sciences, Chemistry, Oxygen–haemoglobin dissociation curve, Kinetics, Pharmaceutical Preparations, Mechanism of action, Hemoglobin, medicine.symptom, 030217 neurology & neurosurgery, Oxygen binding, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5af01e34655d4b4a7484cb5174e4b58
https://doi.org/10.1016/j.bpj.2021.04.024

المؤلفون: Alberto Ceccon, Nina Kubatova, John M. Louis, G. Marius Clore, Vitali Tugarinov

المصدر: J Phys Chem B

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Lipid Bilayers, Liposomes, Materials Chemistry, Nanoparticles, Physical and Theoretical Chemistry, Ubiquitins, Article, Surfaces, Coatings and Films

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdfeb56e064c7721ddb19db4fe1cb06
https://europepmc.org/articles/PMC9357214/

المؤلفون: John M. Louis, Ad Bax, Sai Chaitanya Chiliveri

المصدر: Angew Chem Int Ed Engl

مصطلحات موضوعية: Protein Conformation, alpha-Helical, chemistry.chemical_classification, Circular dichroism, Aqueous solution, 010405 organic chemistry, Intermolecular force, Trimer, Peptide, General Medicine, General Chemistry, Nuclear magnetic resonance spectroscopy, 010402 general chemistry, 01 natural sciences, HIV Envelope Protein gp41, Article, Catalysis, 0104 chemical sciences, Crystallography, chemistry.chemical_compound, Monomer, chemistry, Ionic strength, HIV-1, Humans, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef65133ef23ccfcf7f631edf2fef6a7
https://doi.org/10.1002/anie.202008804

المؤلفون: Hoi Sung Chung, Jae-Yeol Kim, Janghyun Yoo, John M. Louis, Irina V. Gopich

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Photon, Time Factors, Protein Conformation, Science, General Physics and Astronomy, Color, Intrinsically disordered proteins, General Biochemistry, Genetics and Molecular Biology, Article, Quantitative Biology::Subcellular Processes, 03 medical and health sciences, Single-molecule biophysics, Fluorescence Resonance Energy Transfer, Spectroscopy, lcsh:Science, Physics, Physics::Biological Physics, Photons, Quantitative Biology::Biomolecules, Multidisciplinary, Microscopy, Confocal, Photobleaching, 030102 biochemistry & molecular biology, Proteins, General Chemistry, Single-molecule FRET, Models, Theoretical, Kinetics, 030104 developmental biology, Förster resonance energy transfer, Protein folding, lcsh:Q, Biological system, Excitation, Algorithms, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1821c7531b40efbf0437923249105f83
https://doaj.org/article/43303b5b95fe4c4c8636c35d24a12b28

المؤلفون: Sebanti Gupta, John M. Louis, Robert Tycko

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Anti-HIV Agents, Protein Conformation, viruses, medicine.medical_treatment, HIV Infections, Peptide, Virus Replication, 010402 general chemistry, gag Gene Products, Human Immunodeficiency Virus, 01 natural sciences, Isotopic labeling, 03 medical and health sciences, chemistry.chemical_compound, Drug Resistance, Viral, Side chain, medicine, Humans, chemistry.chemical_classification, Multidisciplinary, Protease, Maturation inhibitor, Virus Assembly, Virion, Succinates, Biological Sciences, Viral membrane, Peptide Fragments, Triterpenes, 0104 chemical sciences, 030104 developmental biology, Capsid, chemistry, HIV-1, Biophysics, Capsid Proteins, Bevirimat

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c038b2ac42c4cc5806c6a4300ca7617b
https://doi.org/10.1073/pnas.1917755117

المؤلفون: Sai Chaitanya Chiliveri, John M. Louis, Robert B. Best, Ad Bax

المصدر: Journal of molecular biology. 434(16)

مصطلحات موضوعية: Protein Folding, Time Factors, Protein Domains, Structural Biology, Lipid Bilayers, HIV-1, Humans, Thermodynamics, Virus Internalization, Molecular Biology, Nuclear Magnetic Resonance, Biomolecular, HIV Envelope Protein gp41

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4422d56b44aecfbe8d2f9e35acfe1b88
https://pubmed.ncbi.nlm.nih.gov/35700771

المؤلفون: John M Louis, James L Baber, Rodolfo Ghirlando, Annie Aniana, Ad Bax, Julien Roche

المصدر: PLoS ONE, Vol 11, Iss 8, p e0160597 (2016)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC4981318?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/2b9902b48a1649afa656f6d933c16d97

الاتاحة: https://doi.org/10.1371/journal.pone.0160597
https://doaj.org/article/2b9902b48a1649afa656f6d933c16d97