المؤلفون: Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes, Monica L. Guzman, Constanze Bonifer, John H. Bushweller

المصدر: EBioMedicine, Vol 8, Iss C, Pp 117-131 (2016)

مصطلحات موضوعية: CBFβ, RUNX, PPI, Transcription factor inhibitor, Leukemia, Triple negative breast cancer, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235239641630175X; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/850cfca578ff44cc88f4d9d260010cb6

المؤلفون: Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes, Monica L. Guzman, Constanze Bonifer, John H. Bushweller

المصدر: EBioMedicine, Vol 25, Iss C, p 188 (2017)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396417304358; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/0b1d01d5ffc84fc19361f34993b36b15

المؤلفون: Katelyn E. Heimbruch, Joseph B. Fisher, Cary T. Stelloh, Emily Phillips, Michael H. Reimer, Adam J. Wargolet, Alison E. Meyer, Kirthi Pulakanti, Aaron D. Viny, Jessica J. Loppnow, Ross L. Levine, John Anto Pulikkan, Nan Zhu, Sridhar Rao

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-021-86646-9; https://doaj.org/toc/2045-2322; https://doaj.org/article/4bea0347dc9d49beb5298d2cdd70741f

الاتاحة: https://doi.org/10.1038/s41598-021-86646-9
https://doaj.org/article/4bea0347dc9d49beb5298d2cdd70741f

المؤلفون: Philomina Sona Peramangalam, Sridevi Surapally, Shikan Zheng, Robert Burns, Nan Zhu, Sridhar Rao, Carsten Muller-Tidow, John A. Pulikkan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::880b97600741ad5f2fad7b9cf7f5b854
https://doi.org/10.1101/2023.03.03.531018

المؤلفون: Mingrui Guo, Hon Man Tim Chan, Qi-Ling Zhou, Omer An, Ying Li, Yangyang Song, Zi Hui Tan, Hui En Vanessa Ng, Philomina Sona Peramangalam, Zhi Qing Tan, Xinang Cao, Eisaku Iwanaga, Masao Matsuoka, Melissa G Ooi, Wei Ying Jen, Liang Piu Koh, Esther Chan, Lip Kun Tan, Yufen Goh, Wilson Wang, Bryan T.H. Koh, Ming Chun Chan, Melissa J. Fullwood, Wee Joo Chng, Motomi Osato, John Anto Pulikkan, Henry Yang, Leilei Chen, Daniel G. Tenen

المصدر: Blood.

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d0435d2c5f0df321ef36a58bd2abbfa
https://doi.org/10.1182/blood.2022015830

المؤلفون: John Anto Pulikkan, Lucio Hernán Castilla

المصدر: Frontiers in Oncology, Vol 8 (2018)

مصطلحات موضوعية: myeloid, leukemia, CBFB-MYH11, CBFβ-SMMHC, preleukemia, clonal evolution, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: http://journal.frontiersin.org/article/10.3389/fonc.2018.00129/full; https://doaj.org/toc/2234-943X; https://doaj.org/article/72385b1e00464d5eb5836a666a5905eb

الاتاحة: https://doi.org/10.3389/fonc.2018.00129
https://doaj.org/article/72385b1e00464d5eb5836a666a5905eb

المؤلفون: Daniel G. Tenen, Sridevi Surapally, John Anto Pulikkan

المصدر: Blood

مصطلحات موضوعية: Oncogene Proteins, Fusion, T-Lymphocytes, Immunology, Biology, Core binding factor, Biochemistry, Core Binding Factor beta Subunit, Consolidation therapy, Mice, Antineoplastic Agents, Immunological, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Animals, Humans, Gene Knock-In Techniques, Molecular Targeted Therapy, neoplasms, Chromosomal inversion, BLOOD Spotlight, Myosin Heavy Chains, Oncogene, Gene Expression Regulation, Leukemic, Myeloid leukemia, Cell Biology, Hematology, Combined Modality Therapy, Gemtuzumab, Xenograft Model Antitumor Assays, Hematopoiesis, Leukemia, Myeloid, Acute, Haematopoiesis, Cell Transformation, Neoplastic, Chromosome Inversion, Core Binding Factor Alpha 2 Subunit, Neoplastic Stem Cells, Cancer research, Immunotherapy, Stem cell, Chromosomes, Human, Pair 16, Forecasting

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2d9d451abf1b238f59ee736d01bbbb
https://doi.org/10.1182/blood.2020009933

المؤلفون: Alison E. Meyer, Sridhar Rao, Aaron D. Viny, Katelyn E. Heimbruch, Adam J. Wargolet, Kirthi Pulakanti, Emily Kristine Phillips, Jessica J. Loppnow, Ross L. Levine, Joseph B. Fisher, John Anto Pulikkan, Nan Zhu, Michael Reimer, Cary Stelloh

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Cohesin complex, Chromosomal Proteins, Non-Histone, Science, Cell Cycle Proteins, Biology, Article, Epigenesis, Genetic, Histones, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, Progenitor cell, Cell Self Renewal, Enzyme Inhibitors, Transcription factor, Cancer genetics, Cells, Cultured, Cancer, Homeodomain Proteins, Multidisciplinary, Cohesin, Myeloid leukemia, DOT1L, Histone-Lysine N-Methyltransferase, medicine.disease, Hematopoietic Stem Cells, Haematopoiesis, Leukemia, Leukemia, Myeloid, Acute, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Medicine, Benzimidazoles, Epigenetics, biological phenomena, cell phenomena, and immunity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b225375546eaeb7f98cc2c5ed6db2e35
https://doaj.org/article/4bea0347dc9d49beb5298d2cdd70741f

المؤلفون: Philomina Sona Peramangalam, Sridevi Surapally, Sridhar Rao, Carsten Müller-Tidow, John Anto Pulikkan

المصدر: Blood. 140:12655-12656

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d06fdf54118531efd41b864fda12c147
https://doi.org/10.1182/blood-2022-170448

المؤلفون: Philomina Sona Peramangalam, Sridevi Surapally, Shikan Zheng, Robert Burns, Nan Zhu, Sridhar Rao, Carsten Müller-Tidow, John Anto Pulikkan

المصدر: Blood. 140:9117-9118

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5f55e21a4fb950e1409645b2b87fce2
https://doi.org/10.1182/blood-2022-170112

المؤلفون: Robert S. Welner, Ann-Sofie Schmolke, Florian Grebien, Christoph Kornauth, John Anto Pulikkan, Bon Q. Trinh, Katrina Vanura, Wolfgang R. Sperr, Angelika Pichler, A Di Ruscio, Ruud Delwel, Elizabeth Heyes, Johannes Zuber, Inês Am Barbosa, Akos Czibere, Heinz Sill, Karin Lind, Lukas Kazianka, J. Klinger, Maurizio Forte, Peter Valent, Gerwin Heller, Lucio H. Castilla, Alex Ebralidze, Philipp B. Staber, Daniel G. Tenen, E. van der Kouwe, Trang Le, C. M. Schweicker, Andreas Spittler, Tea Pemovska, C. Agreiter, S. Surapally

المساهمون: Hematology

المصدر: Blood, 138(15), 1345-1358. American Society of Hematology

مصطلحات موضوعية: Oncogene Proteins, Fusion, Cellular differentiation, Immunology, Biology, Core binding factor, Biochemistry, Chromatin remodeling, Core Binding Factor beta Subunit, RUNX1 Translocation Partner 1 Protein, SDG 3 - Good Health and Well-being, Transcription (biology), hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, Sense (molecular biology), Tumor Cells, Cultured, Humans, Enhancer, Promoter Regions, Genetic, Transcription factor, Gene Expression Regulation, Leukemic, Myeloid leukemia, Cell Biology, Hematology, Cell biology, Leukemia, Myeloid, Acute, Antisense Elements (Genetics), Core Binding Factor Alpha 2 Subunit, Trans-Activators, Gene Fusion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7beade2cc5e248c28638bbb26d1f474
https://pubmed.ncbi.nlm.nih.gov/34647985

المؤلفون: Daniel G. Tenen, Gerhard Behre, John Anto Pulikkan

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Myeloid, Computational biology, Biology, medicine.disease_cause, Somatic evolution in cancer, Granulopoiesis, Article, 03 medical and health sciences, CEBPA, CCAAT-Enhancer-Binding Protein-alpha, medicine, Animals, Humans, Genetics, Mutation, Master regulator, Hematology, Hematopoietic Stem Cells, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c65e647160c348a16882210f19a8b0d
https://doi.org/10.1038/leu.2017.229

المؤلفون: Alexander Pichler, Gerwin Heller, Emiel van der Kouwe, Akos Czibere, Alexander K. Ebralidze, Heinz Sill, Peter Valent, Bon Q. Trinh, Maurizio Forte, Philipp B. Staber, Wolfgang R. Sperr, Trang Le, John Anto Pulikkan, Andreas Spittler, Lukas Kazianka, Daniel G. Tenen, Karin Lind, Ann-Sofie Schmolke, Robert S. Welner, Johannes Zuber, Katrina Vanura, Lucio H. Castilla, Inês Am Barbosa, Annalisa Di Ruscio, Christoph Kornauth, Ruud Delwel

المصدر: Blood. 136:40-41

مصطلحات موضوعية: Chemistry, Immunology, Sense (molecular biology), Cell Biology, Hematology, Core binding factor, Biochemistry, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4937e27b6798e4d4fcd545979f08f61c
https://doi.org/10.1182/blood-2020-140776

المؤلفون: Lauren Mishra, Mahmut Parlak, Adam Boulton, Cem Kuscu, Venkata Sesha Srimath Tirumala, Mazhar Adli, Yunpeng Zhou, John H. Bushweller, Anuradha Illendula, Yan Gao, Anna Pickin, Charles Schmidt, Jane Gilmour, Kevin A. Janes, John Anto Pulikkan, Roger A. Rajewski, Aravinda Kuntimaddi, Jolanta Grembecka, Lucio H. Castilla, Hongliang Zong, Constanze Bonifer, Monica L. Guzman, Lixin Wang

المصدر: EBioMedicine, Vol 8, Iss C, Pp 117-131 (2016)
Scipedia Open Access
Scipedia SL

مصطلحات موضوعية: 0301 basic medicine, Core Binding Factor alpha Subunits, PPI, lcsh:Medicine, Biology, Core binding factor, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, Medicine, General & Internal, hemic and lymphatic diseases, medicine, Triple negative breast cancer, Transcription factor, Gene, Triple-negative breast cancer, lcsh:R5-920, Leukemia, CBFβ, lcsh:R, General Medicine, medicine.disease, Molecular biology, RUNX, 3. Good health, Cell biology, 030104 developmental biology, RUNX1, chemistry, Stem cell, Transcription factor inhibitor, lcsh:Medicine (General)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc437935f8e8d7537d744c3567746b60
http://www.sciencedirect.com/science/article/pii/S235239641630175X

المؤلفون: Jun Yu, John H. Bushweller, Houda Belaghzal, Job Dekker, Jianhong Ou, Carsten Müller-Tidow, Mahesh Hegde, Lihua Julie Zhu, Scot A. Wolfe, Kelsey O’Hagan, Hafiz M. Ahmad, John Anto Pulikkan, Lucio H. Castilla, Anuradha Illendula

مصطلحات موضوعية: 0301 basic medicine, Myeloid leukemia, Biology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Article, Chromatin, Cell biology, BET inhibitor, 03 medical and health sciences, Leukemia, chemistry.chemical_compound, 030104 developmental biology, RUNX1, chemistry, hemic and lymphatic diseases, medicine, Enhancer, Psychological repression, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c2717d54aa76242091025bdb1c04d3
https://europepmc.org/articles/PMC6211564/

المؤلفون: Roger A. Rajewski, Hongliang Zong, Adam Boulton, Yunpeng Zhou, John Anto Pulikkan, Aravinda Kuntimaddi, Anuradha Illendula, John H. Bushweller, Yan Gao, Liting Xue, Monica L. Guzman, Siddhartha Sen, Jolanta Grembecka, Lucio H. Castilla

المصدر: Science. 347:779-784

مصطلحات موضوعية: Myeloid, Oncogene Proteins, Fusion, Antineoplastic Agents, Biology, Core binding factor, Article, Small Molecule Libraries, Mice, chemistry.chemical_compound, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Animals, Humans, Protein Interaction Maps, Transcription factor, Multidisciplinary, Myeloid leukemia, medicine.disease, Fusion protein, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Haematopoiesis, Leukemia, medicine.anatomical_structure, RUNX1, chemistry, Core Binding Factor Alpha 2 Subunit, Immunology, Cancer research, Benzimidazoles, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef2ac529ed66a037c3e2cab48b02492
https://doi.org/10.1126/science.aaa0314

المؤلفون: John Anto Pulikkan, Lucio H. Castilla

المصدر: Frontiers in Oncology
Frontiers in Oncology, Vol 8 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Myeloid, CBFβ-SMMHC, Mini Review, Preleukemia, clonal evolution, Somatic evolution in cancer, lcsh:RC254-282, preleukemia, 03 medical and health sciences, stem cells, hemic and lymphatic diseases, Medicine, leukemia-initiating cell, business.industry, CBFB-MYH11, leukemia, Myeloid leukemia, Hematopoietic stem cell, biochemical phenomena, metabolism, and nutrition, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, Cancer research, Bone marrow, Stem cell, myeloid, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f014d4ce91cc696d550989db9a03bd
https://pubmed.ncbi.nlm.nih.gov/29755956

المؤلفون: Anuradha Illendula, John H. Bushweller, Jessica Tesell, John Anto Pulikkan, Justine E. Roderick, Jun Yu, Nicole Hermance, Lucio H. Castilla, Lihua Julie Zhu, Michelle A. Kelliher, AHyun Choi

المصدر: Blood. 130(15)

مصطلحات موضوعية: 0301 basic medicine, LMO2, Carcinogenesis, Apoptosis, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Biochemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Basic Helix-Loop-Helix Transcription Factors, MYB, T-Cell Acute Lymphocytic Leukemia Protein 1, Cell Line, Transformed, Lymphoid Neoplasia, Receptors, Notch, Gene Expression Regulation, Leukemic, Hematology, Chromatin, Leukemia, Enhancer Elements, Genetic, RUNX1, 030220 oncology & carcinogenesis, embryonic structures, Core Binding Factor Alpha 2 Subunit, Protein Binding, Cell Survival, Immunology, Biology, Core Binding Factor beta Subunit, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Proto-Oncogene Proteins c-myb, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Gene silencing, Animals, Humans, Transcription factor, Cell Proliferation, Cell Biology, Oncogenes, medicine.disease, 030104 developmental biology, chemistry, Cancer research, Gene Deletion, TAL1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19b3fc80fc276916cd15e46ac6e8385
https://pubmed.ncbi.nlm.nih.gov/29025715

المؤلفون: Liting Xue, Peter J. M. Valk, Lucio H. Castilla, John Anto Pulikkan

المساهمون: Hematology

المصدر: Blood, 124(3), 426-436. American Society of Hematology

مصطلحات موضوعية: MAPK/ERK pathway, Neuroblastoma RAS viral oncogene homolog, Mice, 129 Strain, Myeloid, Oncogene Proteins, Fusion, Cell Survival, MAP Kinase Signaling System, Immunology, Mutation, Missense, Apoptosis, Mice, Transgenic, Biology, Biochemistry, Mice, Proto-Oncogene Proteins, hemic and lymphatic diseases, medicine, Animals, Preleukemia, Gene Knock-In Techniques, Progenitor cell, Monomeric GTP-Binding Proteins, Oncogene Proteins, Leukemia, Experimental, Myeloid Neoplasia, Bcl-2-Like Protein 11, Membrane Proteins, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, medicine.anatomical_structure, Neoplastic Stem Cells, Cancer research, Stem cell, Apoptosis Regulatory Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae1e5345c90d77f9105ba6522c1f394
https://doi.org/10.1182/blood-2013-12-541730

المؤلفون: Lihua Julie Zhu, John Anto Pulikkan, Peter J. M. Valk, Dmitri Madera, Ya-Huei Kuo, Lucio H. Castilla, Saman Abbas, Paul Bradley, Liting Xue, Sean Landrette

المساهمون: Hematology

المصدر: Blood, 120(4), 868-879. American Society of Hematology

مصطلحات موضوعية: Oncogene Proteins, Fusion, Chromosomes, Human, Pair 21, Immunology, Blotting, Western, Molecular Sequence Data, Biology, Real-Time Polymerase Chain Reaction, Biochemistry, Translocation, Genetic, Immunoenzyme Techniques, chemistry.chemical_compound, Mice, Phosphatidylinositol 3-Kinases, Myeloproliferative Disorders, RUNX1 Translocation Partner 1 Protein, Bone Marrow, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Protein kinase B, PI3K/AKT/mTOR pathway, Thrombopoietin, Bone Marrow Transplantation, Cell Proliferation, Myeloid Neoplasia, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Molecular biology, Survival Rate, Haematopoiesis, Leukemia, Leukemia, Myeloid, Acute, RUNX1, chemistry, Core Binding Factor Alpha 2 Subunit, Cancer research, Proto-Oncogene Proteins c-akt, Receptors, Thrombopoietin, Chromosomes, Human, Pair 8, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22723daa2d4dfea7a13c5ae4ddc01749
https://doi.org/10.1182/blood-2012-03-414649