المؤلفون: Dewan, Ramita, Chia, Ruth, Ding, Jinhui, Hickman, Richard A, Stein, Thor D, Abramzon, Yevgeniya, Ahmed, Sarah, Sabir, Marya S, Portley, Makayla K, Tucci, Arianna, Ibáñez, Kristina, Shankaracharya, FNU, Keagle, Pamela, Rossi, Giacomina, Caroppo, Paola, Tagliavini, Fabrizio, Waldo, Maria L, Johansson, Per M, Nilsson, Christer F, Rowe, James B, Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Jabbari, Edwin, Viollet, Coralie, Glass, Jonathan D, Singleton, Andrew B, Silani, Vincenzo, Ross, Owen A, Ryten, Mina, Torkamani, Ali, Tanaka, Toshiko, Ferrucci, Luigi, Resnick, Susan M, Pickering-Brown, Stuart, Brady, Christopher B, Kowal, Neil, Hardy, John A, Van Deerlin, Vivianna, Vonsattel, Jean Paul, Harms, Matt, Morris, Christopher M, Ferrari, Raffaele, Landers, John E, Chiò, Adriano, Gibbs, Jesse Raphael, Dalgard, Clifton L, Scholz, Sonja W, Traynor, Bryan J, Adeleye, Adelani, Alba, Camille, Bacikova, Dagmar, Hupalo, Daniel N, Martinez, Elisa McGrath, Pollard, Harvey B, Sukumar, Gauthaman, Soltis, Anthony R, Tuck, Meila, Zhang, Xijun, Wilkerson, Matthew D, Smith, Bradley N, Ticozzi, Nicola, Fallini, Claudia, Gkazi, Athina Soragia, Topp, Simon D, Kost, Jason, Scotter, Emma L, Kenna, Kevin P, Miller, Jack W, Tiloca, Cinzia, Vance, Caroline, Danielson, Eric W, Troakes, Claire, Colombrita, Claudia, Al-Sarraj, Safa, Lewis, Elizabeth A, King, Andrew, Calini, Daniela, Pensato, Viviana, Castellotti, Barbara, de Belleroche, Jacqueline, Baas, Frank, Asbroek, Anneloor LMA ten, Sapp, Peter C, McKenna-Yasek, Diane, McLaughlin, Russell L, Polak, Meraida, Asress, Seneshaw, Esteban-Pérez, Jesús, Muñoz-Blanco, José Luis, Stevic, Zorica, D’Alfonso, Sandra, Mazzini, Letizia, Comi, Giacomo P, Del Bo, Roberto, Ceroni, Mauro, Gagliardi, Stella, Querin, Giorgia, Bertolin, Cinzia, van Rheenen, Wouter

المصدر: Neuron. 109(3)

مصطلحات موضوعية: Genetics, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Clinical Research, Neurodegenerative, Acquired Cognitive Impairment, Dementia, Frontotemporal Dementia (FTD), Alzheimer's Disease Related Dementias (ADRD), ALS, Rare Diseases, Brain Disorders, Neurosciences, Huntington's Disease, 2.1 Biological and endogenous factors, Aetiology, Neurological, Amyotrophic Lateral Sclerosis, DNA Repeat Expansion, Frontotemporal Dementia, Humans, Huntingtin Protein, Mutation, Whole Genome Sequencing, American Genome Center, FALS Sequencing Consortium, Genomics England Research Consortium, International ALS/FTD Genomics Consortium, International FTD Genetics Consortium, International LBD Genomics Consortium, NYGC ALS Consortium, PROSPECT Consortium, amyotrophic lateral sclerosis, frontotemporal dementia, huntingtin, repeat expansions, whole-genome sequencing, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/01n02333

المؤلفون: Amer Genome Ctr TAGC, FALS Sequencing Consortium, Genomics England Res Consortium, Int ALS FTD Genomics Consortium iA, Int FTD Genetics Consortium IFGC, Int LBD Genomics Consortium iLBDGC, NYGC ALS Consortium, PROSPECT Consortium, Dewan, Ramita, Chia, Ruth, Ding, Jinhui, Johansson, Per M., Jansson, Lilja, Laaksovirta, Hannu, Tienari, Pentti J., Valori, Miko

المساهمون: HUS Neurocenter, Neurologian yksikkö, Department of Neurosciences, Clinicum, Pentti Tienari / Principal Investigator

مصطلحات موضوعية: Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

Relation: We thank contributors who collected samples used in this initiative and the patients and families, whose help and participation made this work possible. This research was supported by the Intramural Research Program of the National Institutes of Health (National Institute on Aging, National Institute of Neurological Disorders and Stroke, project numbers 1ZIAAG000935 [Principal Investigator (PI) Bryan J. Traynor], 1ZIANS003154 [PI Sonja W. Scholz], and 1ZIANS0030033 and 1ZIANS003034 [David S. Goldstein]). Drs. Sidransky, Grisel Lopez, and Tayebi were supported by the Intramural Research Program of the National Human Genome Research Institute. This research was supported by the Italian Ministry of Health (Ricerca Corrente). R.A.H. is a Columbia University Irving Medical Center ADRC Research Education Component trainee (P30 AG066462-01, PI Scott Small) and is supported by grants from the Hereditary Disease Foundation and Huntington Disease Society of America. J.B.R. is supported by the Wellcome Trust (103838) and National Institute for Health Research Cambridge Biomedical Research Centre. J.E.L. was supported by the National Institutes of Health/National Institute of Neurological Disorders (R01NS073873). The American Genome Center is supported by NHLBI grant IAA-A-HL-007.001. The sequencing activities at NYGC were supported by the ALS Association (grant 19-SI-459) and the Tow Foundation. This study used the high-performance computational capabilities of the Biowulf Linux cluster at the National Institutes of Health, Bethesda, MD (https://hpc.nih.gov).; Amer Genome Ctr TAGC , FALS Sequencing Consortium , Genomics England Res Consortium , Int ALS FTD Genomics Consortium iA , Int FTD Genetics Consortium IFGC , Int LBD Genomics Consortium iLBDGC , NYGC ALS Consortium , PROSPECT Consortium , Dewan , R , Chia , R , Ding , J , Johansson , P M , Jansson , L , Laaksovirta , H , Tienari , P J & Valori , M 2021 , ' Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis ' , Neuron , vol. 109 , no. 3 , pp. 448-460.e4 . https://doi.org/10.1016/j.neuron.2020.11.005; ORCID: /0000-0002-2380-8999/work/130603193; http://hdl.handle.net/10138/340915; 83137b8e-c892-4664-b76e-8d8d01d59144; 000634806300010

الاتاحة: http://hdl.handle.net/10138/340915

المؤلفون: Ali, Muhammad, Sung, Yun Ju, Wang, Fengxian, Fernández, Maria V, Morris, John C, Fagan, Anne M, Blennow, Kaj, Zetterberg, Henrik, Heslegrave, Amanda, Johansson, Per M, Svensson, Johan, Nellgård, Bengt, Lleó, Alberto, Alcolea, Daniel, Clarimon, Jordi, Rami, Lorena, Molinuevo, José Luis, Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Haass, Christian, Ewers, Michael, Levin, Johannes, Farlow, Martin R, Perrin, Richard J, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dominantly Inherited Alzheimer Network (DIAN), Cruchaga, Carlos

المصدر: PLOS ONE , 17 (5) , Article e0267298. (2022)

مصطلحات موضوعية: Alzheimer's disease, Cerebrospinal fluid, Biomarkers, Positron emission tomography, Cognitive impairment, Heterozygosity, Medical risk factors, Dementia

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10149460/1/Zetterberg_Leveraging%20large%20multi-center%20cohorts%20of%20Alzheimer%20disease%20endophenotypes%20to%20understand%20the%20role%20of%20Klotho%20heterozygosity%20on%20disease%20risk_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10149460/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10149460/1/Zetterberg_Leveraging%20large%20multi-center%20cohorts%20of%20Alzheimer%20disease%20endophenotypes%20to%20understand%20the%20role%20of%20Klotho%20heterozygosity%20on%20disease%20risk_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10149460/

المؤلفون: Dewan, Ramita, Chia, Ruth, Ding, Jinhui, Hickman, Richard A, Stein, Thor D, Abramzon, Yevgeniya, Ahmed, Sarah, Sabir, Marya S, Portley, Makayla K, Tucci, Arianna, Ibáñez, Kristina, Shankaracharya, F N U, Keagle, Pamela, Rossi, Giacomina, Caroppo, Paola, Tagliavini, Fabrizio, Waldo, Maria L, Johansson, Per M, Nilsson, Christer F, Rowe, James B, Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Jabbari, Edwin, Viollet, Coralie, Glass, Jonathan D, Singleton, Andrew B, Silani, Vincenzo, Ross, Owen A, Ryten, Mina, Torkamani, Ali, Tanaka, Toshiko, Ferrucci, Luigi, Resnick, Susan M, Pickering-Brown, Stuart, Brady, Christopher B, Kowal, Neil, Hardy, John A, Van Deerlin, Vivianna, Vonsattel, Jean Paul, Harms, Matthew B, Morris, Huw R, Ferrari, Raffaele, Landers, John E, Chiò, Adriano, Gibbs, J Raphael, Dalgard, Clifton L, Scholz, Sonja W, Traynor, Bryan J, Bowser, Robert

المصدر: Neurobiology Articles

Relation: https://scholar.barrowneuro.org/neurobiology/728

الاتاحة: https://scholar.barrowneuro.org/neurobiology/728

المؤلفون: Deming, Yuetiva, Filipello, Fabia, Cignarella, Francesca, Cantoni, Claudia, Hsu, Simon, Mikesell, Robert, Li, Zeran, Del-Aguila, Jorge L, Dube, Umber, Farias, Fabiana Geraldo, Bradley, Joseph, Budde, John, Ibanez, Laura, Fernandez, Maria Victoria, Blennow, Kaj, Zetterberg, Henrik, Heslegrave, Amanda, Johansson, Per M, Svensson, Johan, Nellgård, Bengt, Lleo, Alberto, Alcolea, Daniel, Clarimon, Jordi, Rami, Lorena, Molinuevo, José Luis, Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Ewers, Michael, Harari, Oscar, Haass, Christian, Brett, Thomas J, Benitez, Bruno A, Karch, Celeste M, Piccio, Laura, Cruchaga, Carlos

المصدر: Translational Neuroscience

مصطلحات موضوعية: Alzheimer Disease, Female, Genome-Wide Association Study, Humans, Macrophages, Male, Membrane Glycoproteins, Membrane Proteins, Meta-Analysis as Topic, Multigene Family, Receptors, Immunologic

Relation: https://scholar.barrowneuro.org/neurobiology/2355

الاتاحة: https://scholar.barrowneuro.org/neurobiology/2355
https://doi.org/10.1126/scitranslmed.aau2291

المؤلفون: Wallin, Anders, Kettunen, Petronella, Johansson, Per M., Jonsdottir, Ingibjörg H., Nilsson, Christer, Nilsson, Michael, Eckerström, Marie, Nordlund, Arto, Nyberg, Lars, Sunnerhagen, Katharina S., Svensson, Johan, Terzis, Beata, Wahlund, Lars-Olof, Kuhn, H. Georg

المصدر: BMC Psychiatry. 18

مصطلحات موضوعية: Neurocognitive disorders, Classification of diseases, Disability, Rehabilitation, Mental functions, arning and memory, Executive control, Societal challenge, Stress and environment

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-145373
https://doi.org/10.1186/s12888-018-1615-0
https://umu.diva-portal.org/smash/get/diva2:1189344/FULLTEXT01.pdf

المؤلفون: Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) [research center], Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) [research center], Dewan, Ramita, Chia, Ruth, Ding, Jinhui, Hickman, Richard A., Stein, Thor D., Abramzon, Yevgeniya, Ahmed, Sarah, Sabir, Marya S., Portley, Makayla K., Tucci, Arianna, Ibáñez, Kristina, Shankaracharya, F. N. U., Keagle, Pamela, Rossi, Giacomina, Caroppo, Paola, Tagliavini, Fabrizio, Waldo, Maria L., Johansson, Per M., Nilsson, Christer F., May, Patrick, Krüger, Rejko, Rowe, James B., Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Jabbari, Edwin, Viollet, Coralie, Glass, Jonathan D., Singleton, Andrew B., Silani, Vincenzo, Ross, Owen A., Ryten, Mina, Torkamani, Ali, Tanaka, Toshiko, Ferrucci, Luigi, Resnick, Susan M., Pickering-Brown, Stuart, Brady, Christopher B., Kowal, Neil, Hardy, John A., Van Deerlin, Vivianna, Vonsattel, Jean Paul, Harms, Matthew B., Morris, Huw R., Ferrari, Raffaele, Landers, John E., Chiò, Adriano, Gibbs, J. Raphael, Dalgard, Clifton L., Scholz, Sonja W., Traynor, Bryan J.

مصطلحات الفهرس: amyotrophic lateral sclerosis, frontotemporal dementia, huntingtin, repeat expansions, whole-genome sequencing, info:eu-repo/semantics/article

URL: https://www.cell.com/neuron/fulltext/S0896-6273(20)30883-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627320308837%3Fshowall%3Dtrue
http://orbilu.uni.lu/handle/10993/45883
http://orbilu.uni.lu/bitstream/10993/45883/1/SSRN-id3652331-2.pdf

المؤلفون: Rosén, Christoffer, Mattsson, Niklas, Johansson, Per M., Andreasson, Ulf, Wallin, Anders, Hansson, Oskar, Johansson, Jan-Ove, Lamont, John, Svensson, Johan, Blennow, Kaj, Zetterberg, Henrik

المصدر: Frontiers Aging Neuroscience ; volume 3 ; ISSN 1663-4365

الاتاحة: http://dx.doi.org/10.3389/fnagi.2011.00001

المؤلفون: Paterson, Ross W., Heywood, Wendy E., Heslegrave, Amanda J., Magdalinou, Nadia K., Svensson, Johan, Johansson, Per M., Toombs, Jamie, Fox, Nick C., Zetterberg, Henrik, Mills, Kevin, Schott, Jonathan M.

المصدر: Alzheimer's & Dementia ; volume 11, issue 7S_Part_14 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1016/j.jalz.2015.06.942
https://api.elsevier.com/content/article/PII:S1552526015011796?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1552526015011796?httpAccept=text/plain
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2Fj.jalz.2015.06.942
https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2015.06.942
https://onlinelibrary.wiley.com/doi/full-xml/10.1016/j.jalz.2015.06.942

المؤلفون: Johansson, Per M

مصطلحات موضوعية: Aging, Alzheimer, Cerebrospinal, Hormones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1149::e0adf15fc3f326916b606385c455bd80

المؤلفون: Johansson, Per M

مصطلحات موضوعية: Hormones, Aging, Cerebrospinal, Alzheimer

وصف الملف: application/pdf

Relation: I. Cerebrospinal fluid biomarkers for Alzheimer’s disease – diagnostic performance in a homogeneous monocenter population. Johansson P§, Mattsson N§, Hansson O, Wallin A, Johansson JO, Andreasson U, Zetterberg H, Blennow K, Svensson J. §Contributed equally. J Alzheimers Dis. 2011; 24(3): 537-546. ::PMID::21297262; II. Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer’s disease. Johansson P, Åberg D, Johansson J-O, Mattsson N, Hansson O, Ahrén B, Isgaard J, Åberg ND, Blennow K, Zetterberg H, Wallin A, Svensson J. Psychoneuroendocrinology. 2013; Epub ahead of print. ::PMID::23473966; III. Reduced cerebrospinal fluid level of thyroxine in patients with Alzheimer’s disease. Johansson P, Almqvist EG, Johansson J, Mattsson N, Hansson O, Wallin A, Blennow K, Zetterberg H, Svensson J. Psychoneuroendocrinology. 2012; Epub ahead of print. ::PMID::23159010; IV. Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women. Johansson P, Johansson JO, Labrie F, Mattsson N, Hansson O, Blennow K, Zetterberg H, Wallin A, Ohlsson C, Svensson J. Clin Endocrinol (Oxf) 2011; 75(3):301-308. ::PMID::21521348; V. Leukocyte telomere length (LTL) is reduced in stable mild cognitive impairment but low LTL is not associated with conversion to Alzheimer's disease: a pilot study. Movérare-Skrtic S§, Johansson P§, Mattsson N, Hansson O, Wallin A, Johansson JO, Zetterberg H, Blennow K, Svensson J. §Contributed equally. Exp Gerontol 2012; 47(2):179-182. ::PMID::22210159; http://hdl.handle.net/2077/32374

الاتاحة: http://hdl.handle.net/2077/32374

المؤلفون: Deming, Yuetiva, Filipello, Fabia, Cignarella, Francesca, Cantoni, Claudia, Hsu, Simon, Mikesell, Robert, Li, Zeran, Del-Aguila, Jorge L, Dube, Umber, Farias, Fabiana Geraldo, Bradley, Joseph, Budde, John, Ibanez, Laura, Fernandez, Maria Victoria, Blennow, Kaj, Zetterberg, Henrik, Heslegrave, Amanda, Johansson, Per M, Svensson, Johan, Nellgård, Bengt, Lleo, Alberto, Alcolea, Daniel, Clarimon, Jordi, Rami, Lorena, Molinuevo, José Luis, Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Ewers, Michael, Harari, Oscar, Haass, Christian, Brett, Thomas J, Benitez, Bruno A., Karch, Celeste M., Piccio, Laura, Cruchaga, Carlos

المصدر: Science Translational Medicine; August 2019, Vol. 11 Issue: 505

المؤلفون: Paterson, Ross W., Heywood, Wendy E., Heslegrave, Amanda J., Magdalinou, Nadia K., Svensson, Johan, Johansson, Per M., Toombs, Jamie, Fox, Nick C., Zetterberg, Henrik, Mills, Kevin, Schott, Jonathan M.

المصدر: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jul2015 Supplement, Vol. 11 Issue 7, pP645-P646, 1p