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1Academic Journal
المؤلفون: Giulia Callegaro, Johannes P. Schimming, Janet Piñero González, Steven J. Kunnen, Lukas Wijaya, Panuwat Trairatphisan, Linda van den Berk, Kim Beetsma, Laura I. Furlong, Jeffrey J. Sutherland, Jennifer Mollon, James L. Stevens, Bob van de Water
المصدر: iScience, Vol 26, Iss 3, Pp 106094- (2023)
مصطلحات موضوعية: Gene network, Bioinformatics, Transcriptomics, Science
وصف الملف: electronic resource
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المؤلفون: Erika Moro, Johannes P Schimming, José V. Castell, Bas ter Braak, Laia Tolosa, Barbara M.A. van Vugt-Lussenburg, Bob van der Water, Teresa Martínez-Sena, Miguel A. Miranda, Sylvia Escher
المساهمون: Publica
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Archives of Toxicology, 95(6), 2109-2121. Springer Science and Business Media LLC
ARCHIVES OF TOXICOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Archives of Toxicologyمصطلحات موضوعية: Redox-cycling phenols, Plastic seals, 0301 basic medicine, Cytotox CALUX reporter gene assay, Health, Toxicology and Mutagenesis, Diffusion, HepG2 BAC-GFP SRXN1 assay, 010501 environmental sciences, Toxicology, 01 natural sciences, Gas Chromatography-Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, Phenols, Cross-contamination of culture wells, Cell Line, Tumor, Humans, Incubation, 0105 earth and related environmental sciences, Nrf2 CALUX reporter gene assay, Hepatotoxicity, Reproducibility of Results, Hep G2 Cells, General Medicine, In vitro toxicity, In vitro, High-Throughput Screening Assays, Hydroquinones, Quinone, In Vitro Systems, 030104 developmental biology, chemistry, Environmental chemistry, Toxicity, Degradation (geology), Oxidation-Reduction, Redox cycling, Toxicity of phenols, High-content imaging
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المؤلفون: Paul Jennings, Giada Carta, Johannes P Schimming, Erik H.J. Danen, Marcel Leist, Giulia Callegaro, Nanette G Vrijenhoek, Joost B. Beltman, Anna Forsby, Johannes Delp, Andrew White, Bob van de Water, Sylvia E. Le Dévédec, Huan Yang, Wanda van der Stel, Salihanur Darici
المساهمون: Molecular and Computational Toxicology, AIMMS
المصدر: van der Stel, W, Yang, H, Vrijenhoek, N G, Schimming, J P, Callegaro, G, Carta, G, Darici, S, Delp, J, Forsby, A, White, A, le Dévédec, S, Leist, M, Jennings, P, Beltman, J B, van de Water, B & Danen, E H J 2022, ' Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation ', Archives of Toxicology, vol. 96, no. 1, pp. 259-285 . https://doi.org/10.1007/s00204-021-03160-7
Archives of Toxicology, 96
Archives of Toxicology
Archives of Toxicology, 96(1), 259-285. Springer Verlagمصطلحات موضوعية: Health, Toxicology and Mutagenesis, Mitochondrial toxicity, ETC complex inhibitors, High-content imaging, TempO-Seq, DILI, Oxidative phosphorylation, Toxicology, ETC Complex Inhibitors, Electron Transport, ddc:570, medicine, Gene silencing, Humans, Glycolysis, Viability assay, Electron Transport Complex I, Mitochondrial toxicity, Chemistry, Endoplasmic reticulum, Mitochondrial Toxicity, ETC complex inhibitors, General Medicine, Hep G2 Cells, medicine.disease, Cell biology, Mitochondria, In Vitro Systems, medicine.anatomical_structure, High-Content Imaging, Hepatocyte, Unfolded protein response, Hepatocytes, TempO-Seq, DILI, High-content imaging
وصف الملف: application/pdf
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المؤلفون: Anja Wilmes, Tobias Strassfeld, Harry Vrieling, Manoj Kumar, Balázs Mihalik, Costanza Rovida, Giorgia Pallocca, Nanette G Vrijenhoek, Ciarán Fisher, Bart van der Burg, Thomas Braunbeck, Xenia Dolde, Alice Krebs, Zofia Janstova, Béla Z. Schmidt, Wiebke Albrecht, Jan G. Hengstler, Tim Brecklinghaus, David A. Fluri, J. J. W. A. Boei, Thomas Exner, Marcel Leist, Tanja Waldmann, Jaffar Kisitu, Anna-Katharina Holzer, Manuel Pastor, Joh Dokler, Andrea Paola Cediel Ulloa, Paul Jennings, Barbara M.A. van Vugt-Lussenburg, Bas ter Braak, Bob van de Water, Anna Forsby, Maja Brajnik, Wolfgang Moritz, Catherine M. Verfaillie, Johannes P Schimming, Rebecca von Hellfeld, Alice Limonciel, Francois Busquet, Julianna Kobolák, Ugis Sarkans, Regina Stöber, Jessica Lundqvist, Andras Dinnyes
المساهمون: Molecular and Computational Toxicology, AIMMS
المصدر: Archives of Toxicology
Archives of Toxicology, 94(7), 2435-2461. Springer Verlag
Archives of Toxicology, 94(7), 2435-2461. SPRINGER HEIDELBERG
Krebs, A, van Vugt-Lussenburg, B M A, Waldmann, T, Albrecht, W, Boei, J, Ter Braak, B, Brajnik, M, Braunbeck, T, Brecklinghaus, T, Busquet, F, Dinnyes, A, Dokler, J, Dolde, X, Exner, T E, Fisher, C, Fluri, D, Forsby, A, Hengstler, J G, Holzer, A-K, Janstova, Z, Jennings, P, Kisitu, J, Kobolak, J, Kumar, M, Limonciel, A, Lundqvist, J, Mihalik, B, Moritz, W, Pallocca, G, Ulloa, A P C, Pastor, M, Rovida, C, Sarkans, U, Schimming, J P, Schmidt, B Z, Stöber, R, Strassfeld, T, van de Water, B, Wilmes, A, van der Burg, B, Verfaillie, C M, von Hellfeld, R, Vrieling, H, Vrijenhoek, N G & Leist, M 2020, ' The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods ', Archives of Toxicology, vol. 94, no. 7, pp. 2435-2461 . https://doi.org/10.1007/s00204-020-02802-6
Archives of Toxicology, 94(7), 2435-2461
Archives of toxicology, 94:2435-2461مصطلحات موضوعية: 0301 basic medicine, Test data generation, Computer science, Health, Toxicology and Mutagenesis, Data validation, HAZARD ASSESSMENT, Toxicology, CELL-CULTURE PRACTICE, Documentation, Policy Making, Cells, Cultured, Zebrafish, media_common, EPITHELIAL-CELLS, General Medicine, data processing, GIVIMP, in vitro toxicology, metadata, nuclear receptor, Test (assessment), Strategy implementation, Europe, Data processing, In Vitro Systems, NEURAL CREST MIGRATION, Life Sciences & Biomedicine, REPRODUCTIVE TOXICITY, Risk Assessment, 03 medical and health sciences, SDG 17 - Partnerships for the Goals, ddc:570, Terminology as Topic, Toxicity Tests, media_common.cataloged_instance, Animals, Humans, European union, Retrospective Studies, In vitro toxicology, Electronic Data Processing, Metadata, Science & Technology, business.industry, 030111 toxicology, Reproducibility of Results, CALUX METHOD, IN-VITRO, Pipeline (software), DRUG DISCOVERY, 030104 developmental biology, Nuclear receptor, DEVELOPMENTAL NEUROTOXICITY DNT, Government Regulation, Software engineering, business, EMBRYONIC STEM-CELLS
وصف الملف: application/pdf; Print-Electronic
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المؤلفون: Johannes P Schimming, Jeffrey J. Sutherland, Giulia Callegaro, James L. Stevens, B. van de Water, Lukas S Wijaya, Steven J. Kunnen
المصدر: Toxicology Letters. 350:S228
مصطلحات موضوعية: In vivo, Rat liver, General Medicine, Biology, Toxicology, In vitro, Cell biology
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المصدر: Methods in molecular biology (Clifton, N.J.). 1981
مصطلحات موضوعية: Microscopy, Cholestasis, Microscopy, Fluorescence, Hepatocytes, Humans, Hep G2 Cells, Chemical and Drug Induced Liver Injury, Signal Transduction
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المصدر: Methods in Molecular Biology
Methods in Molecular Biology-Experimental Cholestasis Research
Methods in Molecular Biology ISBN: 9781493994199مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Gene knockdown, medicine.medical_treatment, Oxidative phosphorylation, Biology, medicine.disease, medicine.disease_cause, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cytokine, Cholestasis, Live cell imaging, 030220 oncology & carcinogenesis, Cellular stress response, medicine, Oxidative stress
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المؤلفون: Joost B. Beltman, Jan P. Langenberg, Johannes P Schimming, Luc J M Bischoff, Bob van de Water, Isoude A. Kuijper, Bas ter Braak, Daan Noort, Liesanne Wolters
المساهمون: TNO Defensie en Veiligheid
المصدر: Archives of Toxicology
Archives of Toxicology, 93(2), 435-451مصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, Cell, 010501 environmental sciences, medicine.disease_cause, Toxicology, 01 natural sciences, environment and public health, Green fluorescent protein, Soft electrophiles, Oxidoreductases Acting on Sulfur Group Donors, Gene knockdown, TS - Technical Sciences, Kelch-Like ECH-Associated Protein 1, Chemistry, Nuclear Proteins, Hep G2 Cells, General Medicine, respiratory system, Observation, Weapon & Protection Systems, Molecular Imaging, Cell biology, Protein Transport, medicine.anatomical_structure, Toxicity, Single-Cell Analysis, MafG Transcription Factor, HepG2, NF-E2-Related Factor 2, Green Fluorescent Proteins, Srxn1, Defence Research, Context (language use), Defence, Safety and Security, digestive system, Nrf2, Xenobiotics, Repeated exposure, 03 medical and health sciences, Live cell imaging, Toxicity Tests, medicine, Humans, MafF Transcription Factor, 0105 earth and related environmental sciences, Dose-Response Relationship, Drug, Maleates, CBRN - CBRN Protection, Hydroquinones, Repressor Proteins, 030104 developmental biology, Cell culture, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: L.J.M. Bischoff, B. van de Water, Johannes P Schimming, B. ter Braak
المصدر: Toxicology Letters. 295:S126
مصطلحات موضوعية: Liver injury, Biochemistry, Chemistry, medicine, Identification (biology), General Medicine, Toxicology, medicine.disease_cause, medicine.disease, Oxidative stress