المؤلفون: Søren Østergaard, Johan F. Paulsson, Jacob Kofoed, Franziska Zosel, Jørgen Olsen, Claus Bekker Jeppesen, Jane Spetzler, Lars Ynddal, Luise Gram Schleiss, Berit Østergaard Christoffersen, Kirsten Raun, Ulrich Sensfuss, Flemming Seier Nielsen, Rasmus Jørgensen, Birgitte S. Wulff

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/cec7ec4e645c44c5a30946919c1e7741

المؤلفون: Rasmus Jorgensen, Luise Gram Schleiss, Kirsten Raun, Jacob Kofoed, Claus Bekker Jeppesen, Birgitte Schjellerup Wulff, Berit Østergaard Christoffersen, Jørgen Olsen, Lars Ynddal, Franziska Zosel, Ulrich Sensfuss, Johan F. Paulsson, Søren Østergaard, Jane Spetzler, Flemming S Nielsen

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports

مصطلحات موضوعية: Swine, Science, Serum albumin, Peptide, Lipid-anchored protein, Medicinal chemistry, CHO Cells, Biochemistry, Article, Acylation, Lipopeptides, Cricetulus, In vivo, Cricetinae, Potency, Animals, Humans, Peptide YY, Obesity, chemistry.chemical_classification, Pharmacology, Lead optimization, Multidisciplinary, biology, Drug discovery, Fatty Acids, Albumin, Fatty acid, Acetylation, Liraglutide, Receptors, Neuropeptide Y, Drug Combinations, HEK293 Cells, chemistry, Drug delivery, biology.protein, Swine, Miniature, Medicine, Female, Anti-Obesity Agents, Peptides, Oligopeptides, Half-Life, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b070773ae97f4392dec87755c1751435
https://doaj.org/article/cec7ec4e645c44c5a30946919c1e7741

المؤلفون: Johan F. Paulsson, Jens Kaalby Thomsen, Annika Lindgren Sjölander, Christian Poulsen, Birgitte Schjellerup Wulff, Per-Olof Wahlund, Kilian Conde-Frieboes, Søren Østergaard, Marie Østergaard Pedersen

المصدر: Pharmaceutical Research. 38:1369-1385

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Stereochemistry, Organic Chemistry, Rational design, Pharmaceutical Science, Peptide, Benzoquinone, chemistry, Covalent bond, Molecular Medicine, Moiety, Potency, Pharmacology (medical), Asparagine, Deamidation, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f411fe986b05fc92f7569a83399866d
https://doi.org/10.1007/s11095-021-03077-x

المؤلفون: Christian, Poulsen, Marie Østergaard, Pedersen, Per-Olof, Wahlund, Annika, Sjölander, Jens Kaalby, Thomsen, Kilian W, Conde-Frieboes, Johan F, Paulsson, Birgitte S, Wulff, Søren, Østergaard

المصدر: Pharmaceutical research. 38(8)

مصطلحات موضوعية: HEK293 Cells, Drug Development, Humans, Peptide YY, Asparagine, Peptide Fragments, Receptors, Neuropeptide Y

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::44eba2d1563d226835592aabd480e098
https://pubmed.ncbi.nlm.nih.gov/34272643

المؤلفون: Johan F Paulsson, Johnny Ludvigsson, Annelie Carlsson, Rosaura Casas, Gun Forsander, Sten A Ivarsson, Ingrid Kockum, Åke Lernmark, Claude Marcus, Bengt Lindblad, Gunilla T Westermark

المصدر: PLoS ONE, Vol 9, Iss 3, p e93053 (2014)

مصطلحات موضوعية: Medicine, Science

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24671002/pdf/?tool=EBI; https://doaj.org/toc/1932-6203; https://doaj.org/article/fe2016a67c664464a2a995edd28a451e

الاتاحة: https://doi.org/10.1371/journal.pone.0093053
https://doaj.org/article/fe2016a67c664464a2a995edd28a451e

المؤلفون: Jacob Kofoed, Rasmus Jorgensen, Birgitte Schjellerup Wulff, Kim G. Madsen, Johan F. Paulsson, Søren Dinesen Østergaard

المصدر: Journal of Medicinal Chemistry. 61:10519-10530

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, medicine.diagnostic_test, 010405 organic chemistry, Proteolysis, Tryptophan, 01 natural sciences, 0104 chemical sciences, Amino acid, 03 medical and health sciences, 030104 developmental biology, Protein structure, chemistry, Biochemistry, Peptide YY, Drug Discovery, medicine, Molecular Medicine, Glucose homeostasis, Receptor, Peptide sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7cd84dac6651c1b1815b41141ba5b1a6
https://doi.org/10.1021/acs.jmedchem.8b01046

المؤلفون: Ehud Cohen, Johan F. Paulsson, Pablo Blinder, Tal Burstyn-cohen, Deguo Du, Gabriela Estepa, Anthony Adame, Hang M. Pham, Martin Holzenberger, Jeffery W. Kelly, Eliezer Masliah, Andrew Dillin

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://download.cell.com/pdf/PIIS0092867409014263.pdf?scriptOff=true.

مصطلحات موضوعية: Most cases of Alzheimer

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.9136; http://download.cell.com/pdf/PIIS0092867409014263.pdf?scriptOff=true

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.9136
http://download.cell.com/pdf/PIIS0092867409014263.pdf?scriptOff=true

المؤلفون: Petr, Zouhar, Günaj, Rakipovski, Muhammad Hamza, Bokhari, Oliver, Busby, Johan F, Paulsson, Kilian W, Conde-Frieboes, Johannes J, Fels, Kirsten, Raun, Birgitte, Andersen, Barbara, Cannon, Jan, Nedergaard

المصدر: American Journal of Physiology-Endocrinology and Metabolism

مصطلحات موضوعية: Blood Glucose, Leptin, insulin receptor antagonist, type 1 diabetes, Adipose Tissue, White, uncoupling protein 1, thermoneutrality, Diabetes Mellitus, Experimental, Eating, Mice, Oxygen Consumption, Adipose Tissue, Brown, Pyruvic Acid, Animals, Humans, Insulin, Insulin-Like Growth Factor I, Mice, Knockout, digestive, oral, and skin physiology, Gluconeogenesis, Glucagon, Receptor, Insulin, Disease Models, Animal, Diabetes Mellitus, Type 1, Corticosterone, Peptides, Transcriptome, hormones, hormone substitutes, and hormone antagonists, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::63eabe2f880be82adf1e7bb2d9cc7e8d
https://pubmed.ncbi.nlm.nih.gov/31743040

المؤلفون: Emil Egecioglu, Majken Dalgaard, Marie Østergaard Pedersen, Birgitte Schjellerup Wulff, Mikala Skydsgaard, Alan Broadmeadow, Clare J. Chesher, Ridhirama Bhuwania, Esther Bloem, Emma Moore, Manuel Tena-Sempere, Hannah Williams, Lærke W. Andersen, Pia Søndergaard Galle, Florian Bolze, Johan F. Paulsson

المصدر: Toxicology and Applied Pharmacology. 404:115152

مصطلحات موضوعية: Male, 0301 basic medicine, Hypothalamo-Hypophyseal System, medicine.medical_specialty, Uterus, Hypothalamic–pituitary–gonadal axis, Toxicology, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Kisspeptin, Thinness, Hypogonadotropic hypogonadism, Internal medicine, Testis, Weight Loss, medicine, Animals, Testosterone, Pharmacology, Kisspeptins, business.industry, Leptin, Pituitary gonadal axis, medicine.disease, Rats, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Hypothalamus, 030220 oncology & carcinogenesis, Anti-Obesity Agents, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711c0139312e6bed6d38c6b05112dbcd
https://doi.org/10.1016/j.taap.2020.115152

المؤلفون: Søren, Østergaard, Jacob, Kofoed, Johan F, Paulsson, Kim Grimstrup, Madsen, Rasmus, Jorgensen, Birgitte S, Wulff

المصدر: Journal of medicinal chemistry. 61(23)

مصطلحات موضوعية: Models, Molecular, HEK293 Cells, Protein Stability, Proteolysis, Humans, Peptide YY, Protein Conformation, beta-Strand, Amino Acid Sequence, Receptors, Neuropeptide Y, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::bdc8e9ec704caefc0f0316c99fc70760
https://pubmed.ncbi.nlm.nih.gov/30399314

المؤلفون: Bo, Xu, Silvana, Vasile, Søren, Østergaard, Johan F, Paulsson, Jasna, Pruner, Johan, Åqvist, Birgitte S, Wulff, Hugo, Gutiérrez-de-Terán, Dan, Larhammar

المصدر: Molecular pharmacology. 93(4)

مصطلحات موضوعية: Binding Sites, HEK293 Cells, Swine, Animals, Humans, Peptide YY, Amino Acid Sequence, Peptide Fragments, Protein Structure, Secondary, Receptors, Neuropeptide Y

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4f5061ef7669cb4f08055397137e096a
https://pubmed.ncbi.nlm.nih.gov/29367257

المؤلفون: Søren L. Pedersen, Dimitrios Stamou, Rasmus Jorgensen, Knud J. Jensen, Oliver Zerbe, Maria Pedersen, Simon Jurt, Birgitte Holst, Johan F. Paulsson, Niels Vrang, Vikram Kjoeller Bhatia

المصدر: Journal of Peptide Science. 18:579-587

مصطلحات موضوعية: Pharmacology, Chemistry, Organic Chemistry, General Medicine, Plasma protein binding, Biochemistry, chemistry.chemical_compound, Protein structure, Membrane, Structural Biology, Docking (molecular), Drug Discovery, Peptide synthesis, Molecular Medicine, Structure–activity relationship, Receptor, Molecular Biology, Peptide sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c354ca3edbe288a32b256df056a0839
https://doi.org/10.1002/psc.2436

المؤلفون: Marie E, Oskarsson, Johan F, Paulsson, Sebastian W, Schultz, Martin, Ingelsson, Per, Westermark, Gunilla T, Westermark

المصدر: The American journal of pathology. 185(3)

مصطلحات موضوعية: Aged, 80 and over, Male, Amyloid, Amyloid beta-Peptides, Brain, Mice, Transgenic, Amyloidosis, Middle Aged, Islet Amyloid Polypeptide, Islets of Langerhans, Mice, Diabetes Mellitus, Type 2, Alzheimer Disease, Animals, Humans, Female, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::28ecdcc4cb404dbf63530666a143af89
https://pubmed.ncbi.nlm.nih.gov/25700985

المؤلفون: Jens Christian Norrild, Jens Kaalby Thomsen, Kristian Strømgaard, Johan F. Paulsson, Louise Albertsen, Julie J. Andersen

مصطلحات موضوعية: Depsipeptide, Circular dichroism, Chemistry, Stereochemistry, digestive, oral, and skin physiology, Organic Chemistry, Neuropeptide Y receptor, Biochemistry, Combinatorial chemistry, chemistry.chemical_compound, Peptide YY, Amide, mental disorders, Drug Discovery, Receptor, Selectivity, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c5a4b1ae73d93f7f05b6894b2811d3
https://europepmc.org/articles/PMC4027376/

المؤلفون: Søren Østergaard, Kristian Strømgaard, Jens Chr. Norrild, Louise Albertsen, Johan F. Paulsson

المصدر: ChemMedChem. 8(9)

مصطلحات موضوعية: Recombinant Fusion Proteins, Molecular Sequence Data, Peptide, Enteroendocrine cell, Biochemistry, Structure-Activity Relationship, Drug Discovery, Escherichia coli, Structure–activity relationship, Peptide YY, Amino Acid Sequence, General Pharmacology, Toxicology and Pharmaceutics, Solid-Phase Synthesis Techniques, Pharmacology, chemistry.chemical_classification, Tetrapeptide, Chemistry, digestive, oral, and skin physiology, Organic Chemistry, Amino acid, Receptors, Neuropeptide Y, Molecular Medicine, Intein, Oligopeptides, hormones, hormone substitutes, and hormone antagonists, Cysteine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e553f5e2541ca662ebe168bf17641c
https://pubmed.ncbi.nlm.nih.gov/23907926

المؤلفون: Lauge Schäffer, Marie-Odile Benoit-Biancamano, Kirsten Dahl, Johan F. Paulsson

المصدر: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 18(4)

مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, Amyloid, Cell Survival, Molecular Sequence Data, Amylin, Peptide, Biology, Cell Line, Islets of Langerhans, In vivo, Internal medicine, Internal Medicine, medicine, Animals, Humans, Viability assay, Amino Acid Sequence, Peptide sequence, Pancreas, chemistry.chemical_classification, geography, geography.geographical_feature_category, Sequence Homology, Amino Acid, Ferrets, Amyloidosis, Islet, Molecular biology, In vitro, Peptide Fragments, Islet Amyloid Polypeptide, Disease Models, Animal, Endocrinology, chemistry, Diabetes Mellitus, Type 2, Cats, Protein Multimerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684d24474e835ee9abee9b3dca13dcf1
https://pubmed.ncbi.nlm.nih.gov/22047620

المؤلفون: Johnny Ludvigsson, See Profile, Annelie Carlsson, Gun Forsander, Ingrid Kockum, Johan F. Paulsson, Rosaura Casas, Gun Fors, Sten A. Ivarsson, Claude Marcus, Bengt Lindblad, Gunilla T. Westermark

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: https://www.researchgate.net/profile/Ake_Lernmark/publication/261138423_High_plasma_levels_of_islet_amyloid_polypeptide_in_young_with_new-onset_of_type_1_diabetes_mellitus/links/00b7d53aa9ef940675000000.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1026.3715

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1026.3715

المؤلفون: Post Print, Johan F Paulsson, Sebastian Schultz, Martin Kohler, Ingo Leibiger, Per-olof Berggren, Gunilla Westermark, Real-time Monitoring, Apoptosis Caspase--like Protease, Gunilla T. Westermark

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://liu.diva-portal.org/smash/get/diva2:227295/FULLTEXT01.pdf.

مصطلحات موضوعية: Induced FRET Reduction Triggered by Amyloid Aggregation

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.645.9016; http://liu.diva-portal.org/smash/get/diva2:227295/FULLTEXT01.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.645.9016
http://liu.diva-portal.org/smash/get/diva2:227295/FULLTEXT01.pdf

المؤلفون: Proislet Amyloid Polypeptide (proiapp, Johan F Paulsson

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://liu.diva-portal.org/smash/get/diva2:23092/FULLTEXT01.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.472.7519; http://liu.diva-portal.org/smash/get/diva2:23092/FULLTEXT01.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.472.7519
http://liu.diva-portal.org/smash/get/diva2:23092/FULLTEXT01.pdf

المؤلفون: Johan Paulsson, Johnny Ludvigsson, Annelie Carlsson, Rosaura Casas, Gun Fors, A. Ivarsson, Ingrid Kockum, Ake Lernmark, Claude Marcus, Bengt Lindblad, Gunilla T, Johan F. Paulsson, Sten A. Ivarsson, Gunilla T. Westermark

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://liu.diva-portal.org/smash/get/diva2:718426/FULLTEXT01.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.463.1015; http://liu.diva-portal.org/smash/get/diva2:718426/FULLTEXT01.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.463.1015
http://liu.diva-portal.org/smash/get/diva2:718426/FULLTEXT01.pdf