المؤلفون: Katherine M Livingstone (11215365), Mun Hua Tan (6660344), Gavin Abbott (3841807), Rachel L Duckham (11215368), Larry Croft (3520565), Joey Ward (3825244), Mark McEvoy (9481205), Michelle A Keske (8461998), Christopher Austin (2336749), Steven J Bowe (11215371)

مصطلحات موضوعية: Uncategorized, Science & Technology, Life Sciences & Biomedicine, Endocrinology & Metabolism, dual energy X-ray absorptiometry, genome-wide association study, loci, bone mass, fat mass, lean mass, body composition, genetics, MECHANISM, INSIGHTS, MASS

Relation: https://figshare.com/articles/journal_contribution/Discovery_Genome-Wide_Association_Study_of_Body_Composition_in_4_386_Adults_From_the_UK_Biobank_s_Pilot_Imaging_Enhancement_Study/15088500

الاتاحة: https://doi.org/10.26181/61076245d2750

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Genes_associated_with_MCP_in_MAGMA_gene-level_analyses_of_GWAS_meta-analysis_output_/14388777

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s003

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Table_accompanying_Venn_diagram_of_genes_associated_with_multisite_chronic_pain_in_MAGMA_gene-level_analyses_/14388774

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s002

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/OMIM_and_DrugBank_derived_information_female_MCP_/14388789

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s007

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/OMIM_and_DrugBank_derived_information_male_MCP_/14388786

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s006

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Expression_of_genes_associated_with_female_MCP_in_MAGMA_analyses_across_neural_and_non-neural_tissues_/14388783

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s005

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Genetic_correlations_between_MCP_and_other_disorders_and_traits_/14388771

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s001

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Association_between_male_MCP_PRS_and_CWP_in_men_/14388792

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s008

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Association_between_female_MCP_PRS_and_CWP_in_women_/14388795

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s009

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/S4_Table_Expression_of_genes_associated_with_male_MCP_in_MAGMA_analyses_across_neural_and_non-neural_tissues_TPM_transcripts_per_million_DRG_dorsal_root_ganglion_h_DRG_enrich_DRG_enrichment_score_h_entropy_normalized_Shannon_s_entropy_h_neu/14388780

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s004

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Tissue_Expression_of_MCP-associated_Genes_male_53_tissues_/14388798

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s010

المؤلفون: Keira J. A. Johnston (6836690), Joey Ward (3825244), Pradipta R. Ray (6422666), Mark J. Adams (2954100), Andrew M. McIntosh (7879028), Blair H. Smith (7726100), Rona J. Strawbridge (7718663), Theodore J. Price (578065), Daniel J. Smith (388567), Barbara I. Nicholl (8730138), Mark E. S. Bailey (8499450)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Biotechnology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, DRG, DCC, sex-specific polygenic risk scores, sex-stratified GWAS outputs, dorsal root ganglion, transcript abundance level, Sex-stratified genome-wide associat., expression pattern enrichment, SNP, UK Biobank Chronic pain, sex-specific MCP associations, sex differences, MCP-associated genes, sex-specific pleiotropy, Multisite Chronic Pain

Relation: https://figshare.com/articles/journal_contribution/Tissue_Expression_of_MCP-associated_Genes_female_53_tissues_/14388801

الاتاحة: https://doi.org/10.1371/journal.pgen.1009428.s011

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/Power_calculations_/21791200

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s004

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/figure/Pleiotropy_assessment_for_PCSK9_eQTL_and_mood-disorder_related_trait_using_SMR_/21791194

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s002

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/SMR_results_for_GTEx_cohort_/21791203

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s005

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/figure/SMR_association_of_i_PCSK9_i_and_i_USP24_i_gene-expression_levels_with_phenotypes_of_interest_/21790603

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s001

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/Details_of_GWAS_used_as_outcomes_/21791197

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s003

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/SMR_results_for_replication_cohorts_/21791206

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s006

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/SMR_results_for_i_PCSK9_i_pleiotropic_analyses_/21791209

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s007

المؤلفون: Alisha Aman (12261387), Eric A. W. Slob (11654664), Joey Ward (3825244), Breda Cullen (489583), Nicholas Graham (815122), Donald M. Lyall (7783649), Naveed Sattar (8785), Rona J. Strawbridge (7718663)

مصطلحات موضوعية: Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, wide association studies, nearby genes demonstrated, major depressive disorder, used genetic variants, div >< p, three mood disorder, pcsk9 protein levels, causal adverse effect, mood disorder, causal effects, adverse impact, genetic variation, genetic reduction, mood instability, mood disorders, expression levels, value range, usp24 <, therefore pcsk9, target effects, results suggest, related traits, region acts, recent years, potential impact, pcsk9 <

Relation: https://figshare.com/articles/dataset/Cross-tissue_MR_results_/21791212

الاتاحة: https://doi.org/10.1371/journal.pone.0279381.s008