المؤلفون: Fabiola Silva Angulo, Claudine Vanessa Joseph, Lou Delval, Lucie Deruyter, Séverine Heumel, Marie Bicharel, Patricia Brito Rodrigues, Valentin Sencio, Tom Bourguignon, Marina Gomes Machado, Marie Fourcot, Stéphane Delhaye, Sophie Salomé-Desnoulez, Philippe Valet, Serge Adnot, Isabelle Wolowczuk, Jean-Claude Sirard, Muriel Pichavant, Bart Staels, Joel T. Haas, Ruxandra Gref, Jimmy Vandel, Arnaud Machelart, Hélène Duez, Benoit Pourcet, François Trottein

المصدر: Cell Reports, Vol 44, Iss 2, Pp 115273- (2025)

مصطلحات موضوعية: CP: Microbiology, CP: Immunology, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124725000440; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/daa291d32d904bd9bb15ab8fb98a8451

المؤلفون: Laurent L’homme, Benan Pelin Sermikli, Joel T. Haas, Sébastien Fleury, Sandrine Quemener, Valentine Guinot, Emelie Barreby, Nathalie Esser, Robert Caiazzo, Hélène Verkindt, Benjamin Legendre, Violeta Raverdy, Lydie Cheval, Nicolas Paquot, Jacques Piette, Sylvie Legrand-Poels, Myriam Aouadi, François Pattou, Bart Staels, David Dombrowicz

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/0165911603514238b8604a2d501f0ef0

المؤلفون: Manuel Johanns, Joel T. Haas, Violetta Raverdy, Jimmy Vandel, Julie Chevalier-Dubois, Loic Guille, Bruno Derudas, Benjamin Legendre, Robert Caiazzo, Helene Verkindt, Viviane Gnemmi, Emmanuelle Leteurtre, Mehdi Derhourhi, Amélie Bonnefond, Philippe Froguel, Jérôme Eeckhoute, Guillaume Lassailly, Philippe Mathurin, François Pattou, Bart Staels, Philippe Lefebvre

المصدر: JHEP Reports, Vol 6, Iss 1, Pp 100948- (2024)

مصطلحات موضوعية: Liver homeostasis, daytime rhythmicity, gene expression, metabolomic, transcriptomic, NAFLD, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923002793; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/4fd9fffee41d4c35be393a757aed20a5

المؤلفون: Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c0d2d56ec91641b79809fad780054395

المؤلفون: Jan Freark de Boer, Hilde D. de Vries, Anna Palmiotti, Rumei Li, Marwah Doestzada, Joanne A. Hoogerland, Jingyuan Fu, Anouk M. La Rose, Marit Westerterp, Niels L. Mulder, Milaine V. Hovingh, Martijn Koehorst, Niels J. Kloosterhuis, Justina C. Wolters, Vincent W. Bloks, Joel T. Haas, David Dombrowicz, Bart Staels, Bart van de Sluis, Folkert Kuipers

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1045-1069 (2021)

مصطلحات موضوعية: Bile Acids, Liver, Humanized Mouse Model, Primary Biliary Cholangitis, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X20302034; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/7532521445514e72b3e86eded4106a3d

المؤلفون: Guillaume Grzych, Oscar Chávez-Talavera, Amandine Descat, Dorothée Thuillier, An Verrijken, Mostafa Kouach, Vanessa Legry, Hélène Verkindt, Violeta Raverdy, Benjamin Legendre, Robert Caiazzo, Luc Van Gaal, Jean-Francois Goossens, Réjane Paumelle, Sven Francque, François Pattou, Joel T. Haas, Anne Tailleux, Bart Staels

المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100222- (2021)

مصطلحات موضوعية: NASH, NAFLD, Bile acids, Diabetes, Insulin resistance, Obesity, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555920301567; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/86f4e08dfca4419c8dc1e4b25ab23c55

المؤلفون: Audrey Deprince, Joel T. Haas, Bart Staels

المصدر: Molecular Metabolism, Vol 42, Iss , Pp 101092- (2020)

مصطلحات موضوعية: Dyslipidemia, NAFLD, Cardiovascular disease, Metabolic syndrome, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877820301666; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/ad81825d081d4b7aa17124e5719ea2e2

المؤلفون: Ji Miao, Joel T. Haas, Praveen Manthena, Yanning Wang, Enpeng Zhao, Bhavapriya Vaitheesvaran, Irwin J. Kurland, Sudha B. Biddinger

المصدر: Journal of Lipid Research, Vol 55, Iss 4, Pp 659-667 (2014)

مصطلحات موضوعية: hepatic insulin signaling, cholesterol biosynthesis, sterol regulatory element binding protein, liver insulin receptor knockout, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520376550; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/69fcdeed9f8844519c772ce2240e6837

المؤلفون: Charles A. Harris, Joel T. Haas, Ryan S. Streeper, Scot J. Stone, Manju Kumari, Kui Yang, Xianlin Han, Nicholas Brownell, Richard W. Gross, Rudolf Zechner, Jr. Robert V. Farese

المصدر: Journal of Lipid Research, Vol 52, Iss 4, Pp 657-667 (2011)

مصطلحات موضوعية: neutral lipids, diacylglycerol, sterol esters, lipases, phospholipids, adipogenesis, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520409009; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/08d2d3ba10244a238d6c98b38cd374c5

المؤلفون: Séverine Heumel, Vinícius de Rezende Rodovalho, Charlotte Urien, Florian Specque, Patrícia Brito Rodrigues, Cyril Robil, Lou Delval, Valentin Sencio, Amandine Descat, Lucie Deruyter, Stéphanie Ferreira, Marina Gomes Machado, Adeline Barthelemy, Fabiola Silva Angulo, Joel. T Haas, Jean François Goosens, Isabelle Wolowczuk, Corinne Grangette, Yves Rouillé, Ghjuvan Grimaud, Marie Lenski, Benjamin Hennart, Marco Aurélio Ramirez Vinolo, François Trottein

المصدر: Gut Microbes, Vol 16, Iss 1 (2024)

مصطلحات موضوعية: Influenza, gut microbiota, shotgun metagenomics, metabolomics, indole-3-propionic acid, disease severity, Diseases of the digestive system. Gastroenterology, RC799-869

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984; https://doaj.org/article/618c08bdb540421fb74bab6041041e05

الاتاحة: https://doi.org/10.1080/19490976.2024.2325067
https://doaj.org/article/618c08bdb540421fb74bab6041041e05

المؤلفون: Fanny Lalloyer, Denis A. Mogilenko, Ann Verrijken, Joel T. Haas, Antonin Lamazière, Mostafa Kouach, Amandine Descat, Sandrine Caron, Emmanuelle Vallez, Bruno Derudas, Céline Gheeraert, Eric Baugé, Gaëtan Despres, Eveline Dirinck, Anne Tailleux, David Dombrowicz, Luc Van Gaal, Jerôme Eeckhoute, Philippe Lefebvre, Jean-François Goossens, Sven Francque, Bart Staels

المصدر: Journal of Hepatology.

مصطلحات موضوعية: Hepatology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::22f0765e49345137380ea96eb720d944
https://doi.org/10.1016/j.jhep.2023.05.012

المؤلفون: Manuel Johanns, Joel T. Haas, Violetta Raverdy, Jimmy Vandel, Julie Chevalier-Dubois, Loic Guille, Bruno Derudas, Benjamin Legendre, Robert Caiazzo, Helene Verkindt, Viviane Gnemmi, Emmanuelle Leteurtre, Mehdi Derhourhi, Amélie Bonnefond, Philippe Froguel, Jérôme Eeckhoute, Guillaume Lassailly, Philippe Mathurin, François Pattou, Bart Staels, Philippe Lefebvre

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::82428bc2b02da8b5af2a3b389dba340b
https://doi.org/10.1101/2023.04.05.535334

المؤلفون: Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Hepatology. WILEY
Hepatology
Hepatology, 77(4), 1287-1302. Wiley

مصطلحات موضوعية: Hepatology, Human medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9031fa80e16b9c64c0eac989dc31f93e
http://hdl.handle.net/1887/3479797

المؤلفون: Joel T. Haas, Jan Albert Kuivenhoven, Justina C. Wolters, Andrzej J. Rzepiela, Mathilde Varret, Ann Verhaegen, Valérie Carreau, Szymon Stoma, Anne Philippi, Alaa Othman, Jerome Robert, N. Dalila, Belle V. van Rosmalen, An Verrijken, Arnold von Eckardstein, Bart van de Sluis, Silvija Radosavljevic, Paolo Zanoni, Simon F. Norrelykke, Roger Meier, M. Yalcinkaya, Bart Staels, Andreas Geier, Lucia Rohrer, Michael Stebler, Michele Visentin, Antoine Rimbert, Catherine Boileau, Antonio Gallo, Melinde Wijers, Nicolette C. A. Huijkman, Steve E. Humphries, Jonas Weyler, Freerk van Dijk, Michaela Keel, Srividya Velagapudi, Jean-Pierre Rabès, Marieke Smit, Anne Tybjærg-Hansen, Adriaan van der Graaf, Luisa Vonghia, Yara Abou-Khalil, Sven Francque, Grigorios Panteloglou, Marta Futema, Luc Van Gaal

المساهمون: University hospital of Zurich [Zurich], Universität Zürich [Zürich] = University of Zurich (UZH), Institute for Molecular Systems Biology [ETH Zurich] (IMSB), Department of Biology [ETH Zürich] (D-BIOL), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHU Lille, Scientific Center for Optical and Electron Microscopy (ScopeM), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), University of Groningen [Groningen], unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), St George's, University of London, Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Saint-Joseph de Beyrouth (USJ), University of Copenhagen = Københavns Universitet (UCPH), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), AP-HP. Université Paris Saclay, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Antwerp University Hospital [Edegem] (UZA), University of Antwerp (UA), University of Amsterdam [Amsterdam] (UvA), Columbia University [New York], University Hospital of Würzburg, University College of London [London] (UCL), 603091, ANR-10-LABX-46, 2015T068, CVON2017-2020, AOM06024, 2014/267, Pfizer: 24052829, European Molecular Biology Organization, EMBO: ALTF277-2014, Seventh Framework Programme, FP7, Sixth Framework Programme, FP6: LSHM-CT-2005-018734, Fondation Maladies Rares, FMR, International Atherosclerosis Society, IAS, British Heart Foundation, BHF, European Commission, EC, European Research Council, ERC: 694717, ANR 16-RHUS-0006, Agence Nationale de la Recherche, ANR: ANR-16-RHUS-0007, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF: 310030-185109, 31003A-160126, Fonds De La Recherche Scientifique - FNRS, FNRS, Fonds Wetenschappelijk Onderzoek, FWO: 1802154 N, PG008/08, RG3008, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO: 184.021.007, Universität Zürich, UZH: FK-20-037, We acknowledge the use of data from BIOS-consortium ( http://wiki.bbmri.nl/wiki/BIOS_bios ) which is funded by BBMRI-NL (NWO project 184.021.007). Flow cytometry was performed with equipment of the flow cytometry facility, University of Zurich., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein’s team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 [Medical Research and Development (MRD)] HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose [AGLA] and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Ministère de l’Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHM-CT-2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children’s FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., This work was conducted as part of the TransCard project of the seventh Framework Program (FP7) granted by the European Commission, to J. Albert Kuivenhoven, A. Tybjaerg-Hansen, and A. von Eckardstein (number 603091) as well as partially the FP7 RESOLVE project (to J.T. Haas, B. Staels, A. Verhaegen, S. Francque, L. Van Gaal, and A. von Eckardstein) and the European Genomic Institute for Diabetes (EGID, ANR-10-LABX-46 to B. Staels). Additional work by A. von Eckardstein's team was funded by the Swiss National Science Foundation (31003A-160126, 310030-185109) and the Swiss Systems X program (2014/267 [Medical Research and Development (MRD)] HDL-X). P. Zanoni received funding awards from the Swiss Atherosclerosis Society (Arbeitsgruppe Lipide und Atherosklerose [AGLA] and the DACH Society for Prevention of Cardiovascular Diseases). G. Panteloglou received funding from the University of Zurich (Forschungskredit, grant no. FK-20-037). J. Albert Kuivenhoven is an Established Investigator from the Dutch Heart Foundation (2015T068). J. Albert Kuivenhoven was also supported by GeniusII (CVON2017-2020). The Laboratory for Vascular Translational Science (L.V.T.S.) team is supported by Fondation Maladies Rares, Programme Hospitalier de Recherche Clinique (PHRC) (AOM06024), and the national project CHOPIN (CHolesterol Personalized Innovation), granted by the Agence Nationale de la Recherche (ANR-16-RHUS-0007). Y. Abou Khalil is supported by a grant from Minist?re de l'Education Nationale et de la Technologie (France). J.T. Haas was supported by an EMBO Long Term Fellowship (ALTF277-2014). B. Staels is a recipient of an ERC Advanced Grant (no. 694717). Both are also supported by PreciNASH (ANR 16-RHUS-0006). Research at the Antwerp University Hospital was supported by the European Union: FP6 (HEPADIP Contract LSHMCT- 2005-018734). S. Francque has a senior clinical research fellowship from the Fund for Scientific Research (FWO) Flanders (1802154 N). S.E. Humphries received grants RG3008 and PG008/08 from the British Heart Foundation, and the support of the UCLH NIHR BRC. S.E. Humphries directs the UK Children's FH Register which has been supported by a grant from Pfizer (24052829) given by the International Atherosclerosis Society., ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-16-RHUS-0007,CHOPIN,CHOPIN(2016), Center for Liver, Digestive and Metabolic Diseases (CLDM), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), HAL UVSQ, Équipe, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Service d'Endocrinologie, Métabolisme et Prévention des Maladies Cardio-vasculaires [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

المصدر: Zanoni, P, Panteloglou, G, Othman, A, Haas, J T, Meier, R, Rimbert, A, Futema, M, Khalil, Y A, Norrelykke, S F, Rzepiela, A J, Stoma, S, Stebler, M, Van Dijk, F, Wijers, M, Wolters, J C, Dalila, N, Huijkman, N C A, Smit, M, Gallo, A, Carreau, V, Philippi, A, Rabès, J P, Boileau, C, Visentin, M, Vonghia, L, Weyler, J, Francque, S, Verrijken, A, Verhaegen, A, Van Gaal, L, Van Der Graaf, A, Van Rosmalen, B V, Robert, J, Velagapudi, S, Yalcinkaya, M, Keel, M, Radosavljevic, S, Geier, A, Tybjaerg-Hansen, A, Varret, M, Rohrer, L, Humphries, S E, Staels, B, Van De Sluis, B, Kuivenhoven, J A & Von Eckardstein, A 2022, ' Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome ', Circulation Research, vol. 130, no. 1, pp. 80-95 . https://doi.org/10.1161/CIRCRESAHA.120.318141
Circulation Research
Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩
Circulation research
Circulation research, 130(1), 80-95. LIPPINCOTT WILLIAMS & WILKINS

مصطلحات موضوعية: Spliceosome, Physiology, RNA Splicing, Population, Hypercholesterolemia, Familial hypercholesterolemia, 030204 cardiovascular system & hematology, Biology, 03 medical and health sciences, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Gene expression, medicine, Humans, education, Gene, 030304 developmental biology, 0303 health sciences, Gene knockdown, education.field_of_study, Intron, Nuclear Proteins, Hep G2 Cells, medicine.disease, Molecular biology, Endocytosis, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Lipoproteins, LDL, Cholesterol, HEK293 Cells, Cardiovascular diseases, Liver, Receptors, LDL, Mutation, LDL receptor, Hepatocytes, Spliceosomes, lipids (amino acids, peptides, and proteins), Human medicine, Cardiology and Cardiovascular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7252f24e599e74af7d4245ca33b8f0
https://curis.ku.dk/portal/da/publications/posttranscriptional-regulation-of-the-human-ldl-receptor-by-the-u2spliceosome(80ba810e-1e80-4fb5-8616-1532e1482dba).html

المؤلفون: Hector Alex Saka, J Will Thompson, Yi-Shan Chen, Laura G Dubois, Joel T Haas, Arthur Moseley, Raphael H Valdivia

المصدر: PLoS ONE, Vol 10, Iss 4, p e0124630 (2015)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC4409204?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/562ef71b62a34423b299a931d1120780

الاتاحة: https://doi.org/10.1371/journal.pone.0124630
https://doaj.org/article/562ef71b62a34423b299a931d1120780

المؤلفون: Anne-Françoise Burnol, Tiffany Fougeray, Walter Wahli, Arnaud Polizzi, Lorraine Smith, Hervé Guillou, Marion Régnier, Nicolas Loiseau, Léonie Dopavogui, Yannick Lippi, Benani A, Marine Huillet, Frédéric Lasserre, Joel T. Haas, Anne Fougerat, Pierre Gourdy, Caroline Sommer, Catherine Postic, Blandine Tramunt, Claire Naylies, Sarra Smati, Sandrine Ellero-Simatos, Laurence Gamet-Payrastre, Alexandra Montagner, Duez H

مصطلحات موضوعية: Insulin, medicine.medical_treatment, Circadian clock, Biology, medicine.disease, Cell biology, Insulin receptor, Insulin resistance, Gene expression, medicine, biology.protein, Glucose homeostasis, Circadian rhythm, Homeostasis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a0f301939e50833061859e4910fc8153
https://doi.org/10.1101/2021.02.05.430014

المؤلفون: Tiffany Fougeray, Arnaud Polizzi, Marion Régnier, Anne Fougerat, Sandrine Ellero-Simatos, Yannick Lippi, Sarra Smati, Frédéric Lasserre, Blandine Tramunt, Marine Huillet, Léonie Dopavogui, Juliette Salvi, Emmanuelle Nédélec, Vincent Gigot, Lorraine Smith, Claire Naylies, Caroline Sommer, Joel T. Haas, Walter Wahli, Hélène Duez, Pierre Gourdy, Laurence Gamet-Payrastre, Alexandre Benani, Anne-Françoise Burnol, Nicolas Loiseau, Catherine Postic, Alexandra Montagner, Hervé Guillou

المساهمون: ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut des Maladies Métaboliques et Casdiovasculaires (UPS/Inserm U1297 - I2MC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Transcriptomic impact of Xenobiotics (E23 TRiX), Plateforme Génome & Transcriptome (GET), Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-ToxAlim (ToxAlim), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Service Diabétologie [CHU Toulouse], Pôle Cardiovasculaire et Métabolique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Université Bourgogne Franche-Comté [COMUE] (UBFC), Plateforme Ezop (Ezop), European Genomic Institute for Diabetes - FR 3508 (EGID), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Unité de biologie moléculaire, cellulaire et du développement - UMR5077 (MCD), Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Center for Integrative Genomics - Institute of Bioinformatics, Génopode (CIG), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne = University of Lausanne (UNIL)-Université de Lausanne = University of Lausanne (UNIL), Lee Kong Chian School of Medicine, Nanyang Technological University [Singapour], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Tunisian Ministry of Higher Education, Scientific Research and Technology., LESUR, Hélène, Lee Kong Chian School of Medicine (LKCMedicine), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-ToxAlim (ToxAlim), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Institut Européen de Génomique du Diabète - European Genomic Institute for Diabetes - FR 3508 (EGID), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Cell Reports
Cell Reports, 2022, 39 (2), pp.110674. ⟨10.1016/j.celrep.2022.110674⟩

مصطلحات موضوعية: Insulin Receptor, [SDV]Life Sciences [q-bio], CLOCK, CLOCK Proteins, Gene Expression, General Biochemistry, Genetics and Molecular Biology, Mice, Circadian Clocks, hepatocyte, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Animals, Insulin, Medicine [Science], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, insulin receptor, Circadian, ARNTL Transcription Factors, CP: Metabolism, Receptor, Insulin, Circadian Rhythm, [SDV] Life Sciences [q-bio], [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, circadian, Gene Expression Regulation, Liver, Hepatocytes, CP: Molecular biology, metabolism, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc07a1da7f2a91230aaa9ab4cb824aac
https://pubmed.ncbi.nlm.nih.gov/35508701

المؤلفون: Bart Staels, Audrey Deprince, Joel T. Haas

المساهمون: Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM), Derudas, Marie-Hélène, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, PreciNASH - - PreciNASH2016 - ANR-16-RHUS-0006 - RHUS - VALID, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID

المصدر: Molecular Metabolism, Vol 42, Iss, Pp 101092-(2020)
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101092. ⟨10.1016/j.molmet.2020.101092⟩
Molecular metabolism, 2020, 42, pp.101092. ⟨10.1016/j.molmet.2020.101092⟩
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, lcsh:Internal medicine, [SDV]Life Sciences [q-bio], 030209 endocrinology & metabolism, Review, Disease, Type 2 diabetes, Bioinformatics, digestive system, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Non-alcoholic Fatty Liver Disease, Risk Factors, NAFLD, medicine, Humans, Obesity, lcsh:RC31-1245, Molecular Biology, Dyslipidemias, business.industry, Hypertriglyceridemia, Fatty liver, nutritional and metabolic diseases, Lipid metabolism, Cell Biology, Lipid Metabolism, medicine.disease, Cardiovascular disease, Lipids, Metabolic syndrome, digestive system diseases, 3. Good health, [SDV] Life Sciences [q-bio], 030104 developmental biology, Liver, Dyslipidemia, Cardiovascular Diseases, lipids (amino acids, peptides, and proteins), business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e04192dcef3c8be78adac35b176c283
http://www.sciencedirect.com/science/article/pii/S2212877820301666

المؤلفون: Luisa Vonghia, Sven Francque, Réjane Paumelle, Luc Van Gaal, Marie Joncquel-Chevalier Curt, Jonas Weyler, Guillaume Grzych, Bart Staels, Anne Tailleux, Joel T. Haas, Eveline Dirinck, Marie-Adélaïde Bout, An Verrijken

المصدر: The journal of clinical endocrinology and metabolism

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Cross-sectional study, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Context (language use), Biochemistry, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Insulin resistance, Sex Factors, Non-alcoholic Fatty Liver Disease, Tandem Mass Spectrometry, Internal medicine, Nonalcoholic fatty liver disease, Medicine, Humans, Insulin, Obesity, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, business.industry, Biochemistry (medical), Confounding, nutritional and metabolic diseases, Middle Aged, medicine.disease, Cross-Sectional Studies, Cohort, Homeostatic model assessment, 030211 gastroenterology & hepatology, Female, Human medicine, Insulin Resistance, business, Body mass index, Amino Acids, Branched-Chain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f05c918f511f37bbc03c9f09b58e71
https://pubmed.ncbi.nlm.nih.gov/32271385

المؤلفون: Audrey Deprince, David Dombrowicz, Artemii Nikitin, Bart Staels, Ann Driessen, Sébastien Fleury, An Verrijken, Denis A. Mogilenko, Hélène Dehondt, Samuel Pic, Luisa Vonghia, Bruno Derudas, Sven Francque, Joel T. Haas, Philippe Lefebvre, Luc Van Gaal, Olivier Molendi-Coste, Céline Gheeraert, Lucie Ducrocq-Geoffroy, Eloise Woitrain

المساهمون: Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Department of Gastroenterology and Hepatology [Antwerp, Belgium], Antwerp University Hospital [Edegem] (UZA), Department of Endocrinology, Diabetology and Metabolism [Antwerp, Belgium], Department of Pathology [Antwerp, Belgium], ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), Derudas, Marie-Hélène, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID

المصدر: NATURE METABOLISM
Nature Metabolism
Nature Metabolism, 2019, 1 (6), pp.604-614. ⟨10.1038/s42255-019-0076-1⟩
Nature Metabolism, Nature Publishing Group, 2019, 1 (6), pp.604-614. ⟨10.1038/s42255-019-0076-1⟩

مصطلحات موضوعية: [SDV.IMM] Life Sciences [q-bio]/Immunology, Transcription, Genetic, Endocrinology, Diabetes and Metabolism, Antigen presentation, Inflammation, Biology, Diet, High-Fat, digestive system, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Non-alcoholic Fatty Liver Disease, Physiology (medical), Internal Medicine, medicine, Cytotoxic T cell, Animals, Humans, Gene Regulatory Networks, 030304 developmental biology, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 0303 health sciences, Microarray analysis techniques, Fatty liver, nutritional and metabolic diseases, Cell Biology, Gene signature, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, medicine.disease, digestive system diseases, 3. Good health, Mice, Inbred C57BL, Liver, Cancer research, [SDV.IMM]Life Sciences [q-bio]/Immunology, 030211 gastroenterology & hepatology, Human medicine, Steatohepatitis, medicine.symptom

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca5e9835a5ff6194bbaf51520abadec
https://pubmed.ncbi.nlm.nih.gov/32694642