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1Academic Journal
المؤلفون: Joe M. Segal, Deniz Kent, Daniel J. Wesche, Soon Seng Ng, Maria Serra, Bénédicte Oulès, Gozde Kar, Guy Emerton, Samuel J. I. Blackford, Spyros Darmanis, Rosa Miquel, Tu Vinh Luong, Ryo Yamamoto, Andrew Bonham, Wayel Jassem, Nigel Heaton, Alessandra Vigilante, Aileen King, Rocio Sancho, Sarah Teichmann, Stephen R. Quake, Hiromitsu Nakauchi, S. Tamir Rashid
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2Academic Journal
المؤلفون: Oliver J. Culley, Blaise Louis, Christina Philippeos, Bénédicte Oulès, Matthieu Tihy, Joe M. Segal, Della Hyliands, Gail Jenkins, Ranjit K. Bhogal, Richard C. Siow, Fiona M. Watt
المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
مصطلحات موضوعية: skin, fibroblasts, signalling, epidermis, cell culture, IGF1, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Davide Danovi, S. Ng, S. Sahdeo, L. Chao Zheng, S. J. I. Blackford, Joe M. Segal, Daniel Ebner, A. M. Syanda, V. Chowdary, C. Mueller, Payam Khoshkenar, S. T. Rashid, D. Kent, T. Ismali, Stephanie B Hatch, C. Greer, M. Zieger
مصطلحات موضوعية: Mutation, Kinase, In vivo, business.industry, medicine, Cancer research, Protein degradation, Kinase activity, medicine.disease_cause, business, LRRK2, Small molecule, Proinflammatory cytokine
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المؤلفون: Sven R Quist, Philippe Grange, Matthieu Tihy, Lydia Deschamps, Bénédicte Oulès, Joe M. Segal, Giacomo Donati, Ana-Maria Cujba, Fiona M. Watt, Christina Philippeos, Matteo Vietri Rudan, Ken Natsuga, Nicolas Dupin
المصدر: Nature Communications
Nature Communications, Vol. 11, No 1 (2020) P. 5067
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, Cellular differentiation, Retinoic acid, General Physics and Astronomy, Acne Vulgaris/genetics/metabolism/pathology/physiopathology, Human skin, ddc:616.07, Interleukin-10/genetics/metabolism, B7-H1 Antigen, Pathogenesis, 030207 dermatology & venereal diseases, chemistry.chemical_compound, 0302 clinical medicine, GATA6 Transcription Factor, Acne Vulgaris, Homeostasis, lcsh:Science, Acne, Skin, Multidisciplinary, GATA6, integumentary system, Cell Differentiation, Interleukin-10, Humans, Sebaceous Glands, GATA6 Transcription Factor/genetics/metabolism, Skin/cytology/metabolism/pathology, Mechanisms of disease, medicine.anatomical_structure, Keratinocyte, endocrine system, Science, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, B7-H1 Antigen/genetics/metabolism, medicine, Sebaceous Glands/cytology/metabolism/pathology, business.industry, General Chemistry, medicine.disease, Keratinocytes/cytology/metabolism/pathology, 030104 developmental biology, chemistry, Immunology, lcsh:Q, business
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المؤلفون: Aras N. Mattis, Valerie M. Weaver, Lan Wei, Steve S. Ho, Yusuf A. Hannun, Lorena Pantano, Meghan S. Mooring, Bryan C. Fuchs, Jennifer Y. Chen, Alan C. Mullen, Regina Español-Suñer, Diego dos Santos Ferreira, Dean Yimlamai, Andrew M. Tager, Daniel Canals, Raymond T. Chung, Joe M. Segal, Vikram R. Rao, Amy Yu, Johanna R. Schaub, Mai Sedki, Caroline C. Duwaerts, Sarani Ghoshal, Hsiao-Yen Ma, Nadia M. E. Ayad, Scott M. Turner, Jimmy Kuang-Hsien Hu, Benjamin Newcomb, Megan M. Marlow, Stephanie A. Christenson, Izolda Mileva, Dean Sheppard, Sarah Alsamman
المصدر: Sci Transl Med
Science translational medicine, vol 12, iss 557مصطلحات موضوعية: 0301 basic medicine, Ceramide, Acid Ceramidase, Medical and Health Sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Fibrosis, medicine, Hepatic Stellate Cells, 2.1 Biological and endogenous factors, Animals, Humans, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, biology, Chemistry, Signal Transducing, Signal transducing adaptor protein, Adaptor Proteins, General Medicine, Biological Sciences, medicine.disease, Sphingolipid, Ubiquitin ligase, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Hepatic stellate cell, Hepatic fibrosis, Signal Transduction
وصف الملف: application/pdf
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6Image
المؤلفون: Oliver J. Culley (10527977), Blaise Louis (7522430), Christina Philippeos (667732), Bénédicte Oulès (10527980), Matthieu Tihy (10527983), Joe M. Segal (10527986), Della Hyliands (10527989), Gail Jenkins (10527992), Ranjit K. Bhogal (10527995), Richard C. Siow (10527998), Fiona M. Watt (7522439)
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المؤلفون: Oliver J. Culley (10527977), Blaise Louis (7522430), Christina Philippeos (667732), Bénédicte Oulès (10527980), Matthieu Tihy (10527983), Joe M. Segal (10527986), Della Hyliands (10527989), Gail Jenkins (10527992), Ranjit K. Bhogal (10527995), Richard C. Siow (10527998), Fiona M. Watt (7522439)
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المؤلفون: Nicholas Schaum, Ashley Maynard, Kenneth I. Weinberg, Ishita Bansal, Annie Lo, Christin S. Kuo, Hamid Ebadi, Norma Neff, Bryan D. Merrill, Gunsagar S. Gulati, Michelle B. Chen, Nathalie Khoury, Song E. Lee, Martin J. Zhang, Michael N. Wosczyna, Linda J. van Weele, Lakshmi P. Yerra, James Zou, Matt Fish, Michael F. Clarke, Antoine de Morrée, Lucas M. Waldburger, Kyle J. Travaglini, Maria F. Lugo-Fagundo, Yan Hang, Rasika Patkar, Kerwyn Casey Huang, Weng Chuan Peng, Wan Jin Lu, Astrid Gillich, Andrew May, Aaron Demers, Tony Wyss-Coray, Benoit Lehallier, William Kong, Douglas Brownfield, Robert C. Jones, Katharine M. Ng, Ankit S. Baghel, Patricia K. Nguyen, Rafael Gòmez-Sjöberg, Katherine S. Pollard, Ling Liu, Kevin S. Kao, Róbert Pálovics, Taichi Isobe, Chunyu Zhao, Roel Nusse, Eric J. Rulifson, Maya E. Kumar, Bruce Wang, Philip A. Beachy, Tessa Divita, Ross J. Metzger, Cristina M. Tato, Thomas A. Rando, Marina McKay, Hui Zhang, Oliver Hahn, Jinyi Xiang, Jane Antony, Aaron McGeever, Daniel Staehli, Macy E. Zardeneta, Tal Iram, Olivia Leventhal, Qingyun Li, Angela Oliveira Pisco, Lolita Penland, Krissie Tellez, Marco Mignardi, Brian Yu, Shaheen S. Sikandar, Lincoln Harris, Nicole Almanzar, Corey Cain, Geraldine Genetiano, Foad Green, Davis P. Lee, Carolina Tropini, Laughing Bear Torrez Dulgeroff, Rahul Sinha, Zhen Qi, Stephen R. Quake, Charles Chan, Irving L. Weissman, Sean M. Wu, Jim Karkanias, Ahmad N. Nabhan, Andreas Keller, Margaret Tsui, Alexander Zee, Guruswamy Karnam, Michael S. Haney, Haley du Bois, Robert Puccinelli, Ben A. Barres, Justin L. Sonnenburg, F. Hernan Espinoza, Fabio Zanini, Qiang Gan, Joseph Noh, Lu Zhou, Isaac Bakerman, Aaron M. Kershner, Mark A. Krasnow, Kubilay Demir, Feather Ives, Benson M. George, Guang Li, Dullei Min, Justin Youngyunpipatkul, Mu He, Rene V. Sit, Bernhard M. Kiss, Stephanie D. Conley, Seung K. Kim, Weilun Tan, Soso Xue, M. Windy McNerney, Andrew C. Yang, Kevin A. Yamauchi, Albin Huang, Joe M. Segal, Krzysztof Szade, Michelle Tan, Biter Bilen, Fan Zhang, Spyros Darmanis, Shayan Hosseinzadeh, Xueying Gu, Jonathan K. Lam, Anoop Manjunath, Daniela Berdnik
المصدر: Nature
مصطلحات موضوعية: Male, Aging, T-Lymphocytes, DNA Mutational Analysis, Cell, Computational biology, Biology, Article, Genomic Instability, Transcriptome, Mice, medicine, Animals, Cellular Senescence, Multidisciplinary, Atlas (topology), Immunity, Gene Expression Regulation, Developmental, medicine.anatomical_structure, Liver, Organ Specificity, Ageing, Models, Animal, Female, Single-Cell Analysis
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المؤلفون: Soon Seng, Ng, Kourosh, Saeb-Parsy, Samuel J I, Blackford, Joe M, Segal, Maria Paola, Serra, Marta, Horcas-Lopez, Da Yoon, No, Sotiris, Mastoridis, Wayel, Jassem, Curtis W, Frank, Nam Joon, Cho, Hiromitsu, Nakauchi, Jeffrey S, Glenn, S Tamir, Rashid
المصدر: Biomaterials
مصطلحات موضوعية: Organogenesis, Biomimetic materials, CLF, cholyl-lysyl-flourescence, Biocompatible Materials, IH, iPSC derived hepatic progenitors, ECAM, epithelial cell adhesion molecule, HUVEC, human umbilical endothelial cell, MSC, mesenchymal stem cell, HSGP, heparin sulfate glycoprotein, Polyethylene Glycols, CLDN1, claudin 1, 2D, two-dimensional, TGFβ, transforming growth factor beta, DE, iPSC derived definitive endoderm, Cells, Cultured, Liver stem cells, AFP, alpha-fetoprotein, HNF4a, hepatocyte nuclear factor 4-alpha, Tissue Scaffolds, RNA-seq, RNA-sequence, ZO-1, tight junction protein 1, TGZ, Troglitazone, ICC, inverted colloidal crystal, OCLN, occludin, ECM, extracellular matrix, Organoids, ASGR1, asialoglycoprotein receptor 1, Liver, BSEP, bile-salt efflux pump, HCV, hepatitis C virus, LDLR, low-density lipoprotein receptor, H&E, haematoxylin and eosin, CYC, cyclopamine, Crystallization, SCARB1, scavenger receptor class B type 1, iPSC, induced pluripotent stem cell, Induced Pluripotent Stem Cells, Ln, laminin, Bioengineering, RT-qPCR, reverse transcription-quantitative polymerase chain reaction, Article, CK19, keratin 19, MRP2, multidrug resistance protein 1, Humans, ALB, albumin, PEG, polyethylene glycol, Tissue Engineering, 3D, three-dimensional, Col, collagen, PCA, principle component analysis, FDA, food and drug administration, Fn, fibronectin
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10Validation of a library of cGMP-compliant human pluripotent stem cell lines for use in liver therapy
المؤلفون: Dusko Ilic, Ragai R. Mitry, Michael Sheldon, Soon Seng Ng, Sji Blackford, Ajf King, Joe M. Segal, Jennifer C. Moore, Anil Dhawan, Sheikh Tamir Rashid
مصطلحات موضوعية: Hepatic function, Scaffold, Liver therapy, Hepatic tissue, Progenitor cell, Biology, Induced pluripotent stem cell, Biocompatible material, Phenotype, Cell biology
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المؤلفون: Samuel J I, Blackford, Soon Seng, Ng, Joe M, Segal, Aileen J F, King, Amazon L, Austin, Deniz, Kent, Jennifer, Moore, Michael, Sheldon, Dusko, Ilic, Anil, Dhawan, Ragai R, Mitry, S Tamir, Rashid
المصدر: Stem Cells Translational Medicine
مصطلحات موضوعية: Pluripotent Stem Cells, iPSC, Cellular therapy, Cell Culture Techniques, Cell- and Tissue-Based Therapy, Cell Differentiation, Bioengineering, Hepatocyte differentiation, Cell Line, cGMP, Mice, Liver, hESC, Liver therapy, Hepatocytes, Animals, Humans, Cell transplantation
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المؤلفون: Curtis W. Frank, Da Yoon No, Kourosh Saeb-Parsy, Sheikh Tamir Rashid, Joe M. Segal, Nam-Joon Cho, Blackford Sji, Lopez Mh, Hiromitsu Nakauchi, Seng Ng S, Jeffrey S. Glenn, Maria Paola Serra
مصطلحات موضوعية: 0303 health sciences, Scaffold, Matrigel, Chemistry, Cell biology, Cell therapy, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Organoid, Progenitor cell, Induced pluripotent stem cell, Immortalised cell line, Developmental biology, 030304 developmental biology
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المؤلفون: Joe M. Segal, Deniz Kent, Hiromitsu Nakauchi, Gozde Kar, Tu Vinh, S. Tamir Rashid, Alessandra Vigilante, Samuel J.I. Blackford, Guy Emerton, Bénédicte Oulès, Ryo Yamamoto, Spyros Darmanis, Andrew Bonham, Maria Paola Serra, Daniel J. Wesche, Stephen R. Quake, Rosa Miquel, Soon Seng Ng, Sarah A. Teichmann
مصطلحات موضوعية: Liver injury, 0303 health sciences, Bile duct, Cell, Biology, medicine.disease, In vitro, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Single-cell analysis, 030220 oncology & carcinogenesis, Hepatocyte, medicine, Progenitor cell, 030304 developmental biology, Progenitor
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المؤلفون: Fiona M. Watt, Matthieu Tihy, Philippe Grange, Ken Natsuga, Joe M. Segal, Bénédicte Oulès, Sven R Quist, Giacomo Donati, Nicolas Dupin, Christina Philippeos
المصدر: Journal of Investigative Dermatology. 139:S316
مصطلحات موضوعية: medicine.medical_specialty, GATA6, business.industry, Human skin, Cell Biology, Dermatology, medicine.disease, Biochemistry, Pathogenesis, medicine, business, Molecular Biology, Acne
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المؤلفون: Joe M. Segal, Christopher M. Ward
المصدر: Scientific Reports
Ward, C & Segal, J 2017, ' Novel peptides for deciphering structural and signalling functions of E-cadherin in mouse embryonic stem cells ', Scientific Reports, vol. 7, 41827 . https://doi.org/10.1038/srep41827مصطلحات موضوعية: 0301 basic medicine, Homeobox protein NANOG, Pluripotent Stem Cells, STAT3 Transcription Factor, Transcription, Genetic, Cell Survival, Gene Expression, Cell Communication, Article, 03 medical and health sciences, Kruppel-Like Factor 4, Mice, Structure-Activity Relationship, Gene expression, Animals, Phosphorylation, STAT3, Multidisciplinary, biology, Chemistry, Cadherin, Mouse Embryonic Stem Cells, Nanog Homeobox Protein, Cadherins, Embryonic stem cell, Molecular biology, Hedgehog signaling pathway, Cell biology, 030104 developmental biology, KLF4, biology.protein, Peptides, Signal Transduction
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المؤلفون: Christopher M. Ward, Joe M. Segal, Nicoletta Bobola, Kate Hawkins, Sarah Ritson, Lisa Mohamet, Natalie J Miazga, Francesca Soncin, Catherine L.R. Merry, Maria Keramari
المصدر: Stem cells (Dayton, Ohio). 32(11)
مصطلحات موضوعية: Pluripotent Stem Cells, Mice, 129 Strain, Rex1, Cellular differentiation, Cell Separation, Biology, Leukemia Inhibitory Factor, Epigenesis, Genetic, Animals, Humans, Induced pluripotent stem cell, Promoter Regions, Genetic, Cell potency, Cells, Cultured, Embryonic Stem Cells, Induced stem cells, Cell Differentiation, Cell Biology, DNA Methylation, Cadherins, Embryonic stem cell, Cell biology, Molecular Medicine, Stem cell, Developmental Biology, Adult stem cell, Signal Transduction