المؤلفون: Ying Zhang (40767), Qingsong Yang (491467), Juan Ling (4803120), Lijuan Long (3138999), Hui Huang (4122), Jianping Yin (557395), Meilin Wu (2167708), Xiaoyu Tang (422481), Xiancheng Lin (10721367), Yanying Zhang (3422426), Junde Dong (544304)

مصطلحات موضوعية: Microbiology, Pocillopora damicornis, Beneficial bacterial consortium, High-throughput sequencing, Endozoicomonas

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Shifting_the_microbiome_of_a_coral_holobiont_and_improving_host_physiology_by_inoculation_with_a_potentially_beneficial_bacterial_consortium/14511404

الاتاحة: https://doi.org/10.6084/m9.figshare.14511404.v1

المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers

Relation: https://figshare.com/articles/journal_contribution/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336953

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02085.s004

المؤلفون: Ying Zhang (40767), Qingsong Yang (491467), Juan Ling (4803120), Lijuan Long (3138999), Hui Huang (4122), Jianping Yin (557395), Meilin Wu (2167708), Xiaoyu Tang (422481), Xiancheng Lin (10721367), Yanying Zhang (3422426), Junde Dong (544304)

مصطلحات موضوعية: Microbiology, Pocillopora damicornis, Beneficial bacterial consortium, High-throughput sequencing, Endozoicomonas

Relation: https://figshare.com/articles/dataset/Additional_file_2_of_Shifting_the_microbiome_of_a_coral_holobiont_and_improving_host_physiology_by_inoculation_with_a_potentially_beneficial_bacterial_consortium/14511407

الاتاحة: https://doi.org/10.6084/m9.figshare.14511407.v1

المؤلفون: Ying Zhang (40767), Qingsong Yang (491467), Juan Ling (4803120), Lijuan Long (3138999), Hui Huang (4122), Jianping Yin (557395), Meilin Wu (2167708), Xiaoyu Tang (422481), Xiancheng Lin (10721367), Yanying Zhang (3422426), Junde Dong (544304)

مصطلحات موضوعية: Microbiology, Pocillopora damicornis, Beneficial bacterial consortium, High-throughput sequencing, Endozoicomonas

Relation: https://figshare.com/articles/dataset/Additional_file_3_of_Shifting_the_microbiome_of_a_coral_holobiont_and_improving_host_physiology_by_inoculation_with_a_potentially_beneficial_bacterial_consortium/14511410

الاتاحة: https://doi.org/10.6084/m9.figshare.14511410.v1

المؤلفون: Ying Zhang (40767), Qingsong Yang (491467), Juan Ling (4803120), Lijuan Long (3138999), Hui Huang (4122), Jianping Yin (557395), Meilin Wu (2167708), Xiaoyu Tang (422481), Xiancheng Lin (10721367), Yanying Zhang (3422426), Junde Dong (544304)

مصطلحات موضوعية: Microbiology, Pocillopora damicornis, Beneficial bacterial consortium, High-throughput sequencing, Endozoicomonas

Relation: https://figshare.com/articles/dataset/Additional_file_4_of_Shifting_the_microbiome_of_a_coral_holobiont_and_improving_host_physiology_by_inoculation_with_a_potentially_beneficial_bacterial_consortium/14511413

الاتاحة: https://doi.org/10.6084/m9.figshare.14511413.v1

المؤلفون: Ying Zhang (40767), Qingsong Yang (491467), Juan Ling (4803120), Lijuan Long (3138999), Hui Huang (4122), Jianping Yin (557395), Meilin Wu (2167708), Xiaoyu Tang (422481), Xiancheng Lin (10721367), Yanying Zhang (3422426), Junde Dong (544304)

مصطلحات موضوعية: Microbiology, Pocillopora damicornis, Beneficial bacterial consortium, High-throughput sequencing, Endozoicomonas

Relation: https://figshare.com/articles/dataset/Additional_file_of_Shifting_the_microbiome_of_a_coral_holobiont_and_improving_host_physiology_by_inoculation_with_a_potentially_beneficial_bacterial_consortium/14511416

الاتاحة: https://doi.org/10.6084/m9.figshare.14511416.v1

المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers

Relation: https://figshare.com/articles/dataset/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336947

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02085.s002

المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers

Relation: https://figshare.com/articles/dataset/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336944

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02085.s001

المؤلفون: Malcolm P. Huestis (10493092), Darlene Dela Cruz (10493095), Antonio G. DiPasquale (1274730), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Alberto Gobbi (1508113), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Michael Siu (1503160), Joachim Rudolph (1464982)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, kinase selectivity, vivo evaluation, solubility, Combination Treatment, MEK inhibitor cobimetinib, tumor growth inhibition, NH functionality, pathway inhibition, Strategic substitution, fluoroquinazolinone hinge-binding motif, xenograft mouse model, C 5 position, RAF-specific residue interactions, aryl urea RAF inhibitors, type II pan-RAF inhibitor GNE -0749, Targeting KRAS Mutant Cancers

Relation: https://figshare.com/articles/dataset/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336950

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02085.s003

المؤلفون: Malcolm P. Huestis (10493092), Matthew R. Durk (7052600), Charles Eigenbrot (1346406), Paul Gibbons (114343), Thomas L. Hunsaker (3160575), Hank La (438084), Dennis H. Leung (2106256), Wendy Liu (2057074), Shiva Malek (1346394), Mark Merchant (282025), John G. Moffat (413533), Christine S. Muli (10493098), Christine J. Orr (10493101), Brendan T. Parr (2342548), Frances Shanahan (655624), Christopher J. Sneeringer (10493104), Weiru Wang (640332), Ivana Yen (1346373), Jianping Yin (557395), Joachim Rudolph (1464982), Michael Siu (1503160)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Developmental Biology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, Pyridopyridazinone pan-RAF Kinase I., kinase-selective RAF inhibitors, HCT 116 xenograft mouse model, Targeting KRAS Mutant Cancers, MEK inhibitor cobimetinib, Type II pan-RAF inhibitor GNE -9815, GNE -9815, MAPK pathway modulation, aryl urea RAF inhibitors

Relation: https://figshare.com/articles/journal_contribution/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_Pyridopyridazinone_pan-RAF_Kinase_Inhibitor/14460218

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00063.s001