المؤلفون: Jinqi Liu, Joshua Curtin, Dan You, Stephen Hillerman, Bifang Li-Wang, Rukiye Eraslan, Jenny Xie, Jesse Swanson, Ching-Ping Ho, Simone Oppenheimer, Bethanne M Warrack, Colleen A McNaney, David M Nelson, Jordan Blum, Taeg Kim, Mark Fereshteh, Michael Reily, Petia Shipkova, Anwar Murtaza, Miguel Sanjuan, John T Hunt, Luisa Salter-Cid

المصدر: PLoS ONE, Vol 14, Iss 3, p e0212670 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/7604dc75ad594b68a709196c2f123df0

المؤلفون: Yue Hu, Jenny Xie

المصدر: AIP Advances, Vol 8, Iss 12, Pp 125211-125211-21 (2018)

مصطلحات موضوعية: Physics, QC1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2158-3226

URL الوصول: https://doaj.org/article/510623938d594f9398d1d07055facc9a

المؤلفون: Jenny Xie, Min Peng, Shawna Guillemette, Steven Quan, Stephanie Maniatis, Yuliang Wu, Aditya Venkatesh, Scott A Shaffer, Robert M Brosh, Sharon B Cantor

المصدر: PLoS Genetics, Vol 8, Iss 7, p e1002786 (2012)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3390368?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/55403aa009d0482db1dff30292132bf5

المؤلفون: John L. Gilmore (2864198), Hai-Yun Xiao (1429891), T. G. Murali Dhar (7542971), Michael Yang (660056), Zili Xiao (2123182), Xiaoxia Yang (625366), Tracy L. Taylor (1429903), Kim W. McIntyre (1429864), Bethanne M. Warrack (1436392), Hong Shi (177669), Paul C. Levesque (1429897), Anthony M. Marino (1429900), Georgia Cornelius (1429912), Arvind Mathur (144120), Ding Ren Shen (1429906), Jian Pang (1622326), Mary Ellen Cvijic (1429885), Lois D. Lehman-McKeeman (175275), Huadong Sun (6128699), Jenny Xie (153871), Luisa Salter-Cid (1429873), Percy H. Carter (1355331), Alaric J. Dyckman (1429909)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, S 1P 1 modulator BMS -986104, sphingosine -1-phosphate G-protein-., PK, Exploring Side Chain Modifications, alkyl side chain, PD, S 1P 1, Bicyclic Ligand-Biased Agonists, Safety Profiles Sphingosine -1-phos., phosphate metabolite, S 1P receptors, S 1P

Relation: https://figshare.com/articles/journal_contribution/Bicyclic_Ligand-Biased_Agonists_of_S1P_sub_1_sub_Exploring_Side_Chain_Modifications_to_Modulate_the_PK_PD_and_Safety_Profiles/13639218

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01109.s001

المؤلفون: Jenny Xie

المصدر: The Yale Review. 110:18-22

مصطلحات موضوعية: Literature and Literary Theory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::97cd7f799d5050b14c7c53b75a6b9289
https://doi.org/10.1353/tyr.2022.0002

المؤلفون: Sharon B. Cantor, Andrew Buermeyer, Candace Gilbert, Min Peng, Shawna Guillemette, Jenny Xie

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331d63881d41379ba710f2f5f3b954bd
https://doi.org/10.1158/1940-6207.22524789

المؤلفون: Sharon B. Cantor, Andrew Buermeyer, Candace Gilbert, Min Peng, Shawna Guillemette, Jenny Xie

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3a3962cbfbbf2173950954d24a4278
https://doi.org/10.1158/1940-6207.22524786

المؤلفون: Aberra Fura, Shiuhang Yip, Georgia Cornelius, Hai-Yun Xiao, Qingjie Liu, Sha Li, Ning Li, Nicholas A. Meanwell, Shailesh Dudhgaonkar, Max Ruzanov, Jenny Xie, Zili Xiao, Purnima Khandelwal, Carolyn A. Weigelt, David J. Shuster, Dauh-Rurng Wu, T. G. Murali Dhar, Tara Sherry, Yang Michael G, Kevin Stefanski, Jignesh Nagar, Rex Denton, Qihong Zhao, Peng Li, Silvi A. Chacko, Arun Govindarajan, Robert M. Borzilleri, John S. Sack, Yeheng Zhu, Yunling Song, Dawn Sun, Anjuman Rudra, Mary T. Obermeier, Jinhong Wang, Douglas G. Batt, Venkata Murali

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Membrane permeability, 010405 organic chemistry, Chemistry, Organic Chemistry, Pharmacology, medicine.disease, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, In vivo, RAR-related orphan receptor gamma, Psoriasis, Rheumatoid arthritis, Drug Discovery, medicine, Potency, Inverse agonist

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3296d470de82e26da82050921646783
https://doi.org/10.1021/acsmedchemlett.1c00112

المؤلفون: Alaric J. Dyckman, Lois D. Lehman-McKeeman, Huadong Sun, Hong Shi, Mary Ellen Cvijic, Ding Ren Shen, Xiaoxia Yang, Michael Yang, Tracy L. Taylor, Hai-Yun Xiao, Zili Xiao, Luisa Salter-Cid, Jian Pang, Percy H. Carter, Paul Levesque, Arvind Mathur, John L. Gilmore, Jenny Xie, T. G. Murali Dhar, Georgia Cornelius, Anthony M. Marino, Kim W. McIntyre, Bethanne M. Warrack

المصدر: Journal of Medicinal Chemistry. 64:1454-1480

مصطلحات موضوعية: Chemistry, Metabolite, Arthritis, Pharmacology, medicine.disease, Ligand (biochemistry), chemistry.chemical_compound, Immune system, Pharmacokinetics, In vivo, Drug Discovery, medicine, Molecular Medicine, Receptor, PK/PD models

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3c93ac373a666f79bb2e7b408fdbd2fc
https://doi.org/10.1021/acs.jmedchem.0c01109

المؤلفون: Mian Gao, David J. Shuster, Hai-Yun Xiao, Christine B. Goldstine, Jing Chen, Zhonghui Lu, Victor R. Guarino, Khehyong Ngu, Lisa M. Kopcho, Deepa Calambur, Kurt R. Gregor, Andrew J. Tebben, Jingwu Duan, Luisa Salter-Cid, Hao Lu, Joseph A. Tino, Ning Li, John Hynes, James R. Burke, Joseph Yanchunas, John E. Macor, Steven Sheriff, Dauh-Rurng Wu, Bin Jiang, Patrick J. Shaw, ChiehYing Y. Chang, Jenny Xie, Vojkan Susulic, T. G. Murali Dhar

المصدر: Journal of Medicinal Chemistry. 63:15050-15071

مصطلحات موضوعية: Arthritis, Trimer, Proof of Concept Study, 01 natural sciences, Arthritis, Rheumatoid, Structure-Activity Relationship, 03 medical and health sciences, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Potency, Structure–activity relationship, Naphthyridines, 030304 developmental biology, 0303 health sciences, Molecular Structure, Tumor Necrosis Factor-alpha, Chemistry, medicine.disease, Arthritis, Experimental, Small molecule, 0104 chemical sciences, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Drug Design, Microsomes, Liver, Quinolines, Biophysics, Molecular Medicine, Female, Tumor necrosis factor alpha

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4023f6e8b3a6052dbeee946d81173312
https://doi.org/10.1021/acs.jmedchem.0c01732

المؤلفون: Tara Sherry, John E. Macor, Jinhong Wang, Georgia Cornelius, Shiuhang Yip, Luisa Salter-Cid, Qingjie Liu, Purnima Khandelwal, Carolyn A. Weigelt, Max Ruzanov, John S. Sack, Kevin Stefanski, Jenny Xie, T. G. Murali Dhar, Sha Li, Melissa Yarde, Joseph A. Tino, Qihong Zhao, Dauh-Rurng Wu, Mary T. Obermeier, David J. Shuster, Aberra Fura, Douglas G. Batt, Rex Denton

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: chemistry.chemical_classification, Virtual screening, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Prodrug, Cyclohexanecarboxylic acid, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, RAR-related orphan receptor gamma, Drug Discovery, Moiety, Inverse agonist, Solubility, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cac25cddf4e8f7e9938641eae9eba1
https://doi.org/10.1021/acsmedchemlett.0c00496

المؤلفون: Kuan‐ju Lin, Shalabh Singhal, Shenita Basdeo, Huadong Sun, John Throup, Hannah Huang, Aberra Fura, Ang Liu, Sebastien Bihorel, Ihab G. Girgis, Elizabeth Ludwig, Diane E. Shevell, Jenny Xie, Santanu Dutta

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, Tetrahydronaphthalenes, Lymphocyte, Population, Pharmaceutical Science, Original Manuscript, Pharmacology, BMS‐986166, Placebo, 030226 pharmacology & pharmacy, Models, Biological, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Oral administration, Heart Rate, Heart rate, medicine, Humans, Pharmacology (medical), Computer Simulation, Lymphocyte Count, education, Sphingosine-1-Phosphate Receptors, PK/PD models, education.field_of_study, Dose-Response Relationship, Drug, business.industry, PK/PD, Articles, ALC, Middle Aged, Healthy Volunteers, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pharmacodynamics, Female, business, S1P1R

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bede4651619c4a35110c650d35f35e3
http://europepmc.org/articles/PMC7821288

المؤلفون: Thomas R. Malek, Alicia Santos Savio, Connor J. Dwyer, Jenny Xie, Aixin Yu, Rosmely Hernandez, Mary Struthers, Liping Yu, Jen Bon Lui, Natasha C. Ward, Sunnie Hsiung

المصدر: Diabetes

مصطلحات موضوعية: 0301 basic medicine, Recombinant Fusion Proteins, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, T cell, Mice, Inbred Strains, chemical and pharmacologic phenomena, 030209 endocrinology & metabolism, Immune tolerance, Mice, 03 medical and health sciences, 0302 clinical medicine, T-Lymphocyte Subsets, Diabetes Mellitus, Internal Medicine, medicine, Animals, Humans, IL-2 receptor, Autoantibodies, NOD mice, Type 1 diabetes, business.industry, Interleukin-2 Receptor alpha Subunit, Autoantibody, Receptors, Interleukin-2, hemic and immune systems, Immunotherapy, medicine.disease, 030104 developmental biology, Cytokine, medicine.anatomical_structure, Immunology, Interleukin-2, Female, Immunology and Transplantation, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bfdfe95b7de2b2a96cf36840be32d4
https://doi.org/10.2337/db20-0186

المؤلفون: John L. Gilmore, Kim W. McIntyre, Lois D. Lehman-McKeeman, David Marcoux, Hai-Yun Xiao, Georgia Cornelius, Alaric J. Dyckman, Mary Ellen Cvijic, Jenny Xie, Yang Michael G, T. G. Murali Dhar, Zili Xiao, Tracy L. Taylor, Anthony M. Marino, Ding Ren Shen, Percy H. Carter, Paul Levesque, Arvind Mathur, Huadong Sun, Hong Shi

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Bicyclic molecule, 010405 organic chemistry, Stereochemistry, Aryl, Sphingosine-1-phosphate receptor, Organic Chemistry, Ether, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Potency, PK/PD models, ED50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415fc075f357363f95afa2908797c5ae
https://doi.org/10.1021/acsmedchemlett.0c00333

المؤلفون: Jenny Xie

المصدر: Ploughshares. 46:158-162

مصطلحات موضوعية: Forgetting, General Medicine, Psychology, Cognitive psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83f7092da222e100aeae58366cdc4134
https://doi.org/10.1353/plo.2020.0095

المؤلفون: Carolyn A. Weigelt, Sha Li, David Marcoux, Georgia Cornelius, Qihong Zhao, Mary Ellen Cvijic, John E. Macor, Jingwu Duan, Melissa Yarde, Muthalagu Vetrichelvan, David J. Shuster, Qingjie Liu, Richard Rampulla, Kim W. McIntyre, Mary T. Obermeier, Shiuhang Yip, Purnima Khandelwal, Sureshbabu Vishwakrishnan, Anuradha Gupta, Virna Borowski, Peng Li, Kevin Stefanski, Sridharan Ramlingam, Myra Beaudoin-Bertrand, Nageswara Maddala, Sridhar Vanteru, Percy H. Carter, Arvind Mathur, Aberra Fura, Max Ruzanov, John Hynes, Dauh-Rurng Wu, Jinhong Wang, Luisa Salter-Cid, John S. Sack, Cornelius Lyndon A M, Anurag S. Srivastava, Robert J. Cherney, Kumaravel Selvakumar, Mushkin Basha, Arun Kumar Gupta, Douglas G. Batt, Rex Denton, Sukhen Karmakar, Qing Shi, Ananta Karmakar, Naveen Manjunath, Javed Khan, Jenny Xie, Joseph A. Tino, T. G. Murali Dhar

المصدر: Journal of Medicinal Chemistry. 62:9931-9946

مصطلحات موضوعية: Models, Molecular, Pyrrolidines, Drug Inverse Agonism, Protein Conformation, Pharmacology, 01 natural sciences, Jurkat Cells, Mice, Structure-Activity Relationship, 03 medical and health sciences, Psoriatic arthritis, RAR-related orphan receptor gamma, In vivo, Drug Discovery, medicine, Animals, Humans, Inverse agonist, Structure–activity relationship, Tissue Distribution, 030304 developmental biology, 0303 health sciences, Chemistry, Nuclear Receptor Subfamily 1, Group F, Member 3, medicine.disease, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Nuclear receptor, Drug Design, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eeada291586349dd371c5b816894adb
https://doi.org/10.1021/acs.jmedchem.9b01369

المؤلفون: Robyn H. Guymer, Caroline M. Markey, Ian L. McAllister, Mark C. Gillies, Alex P. Hunyor, Jennifer J. Arnold, Andrew Chang, Adil Syed, Geoffrey Broadhead, Thomas Pham, Thomas Hong, Lily Wong, Meidong Zhu, Shelley Burnett, Nichole Joachim, Wijeyanthy Wijeyakumar, Gabriel Manalang, Cleopatra Mhlanga, Nicole Joachim, Kimperly Spooner, Paul Mitchell, Suriya Foran, Christabel Wilson, Victoria Cossatto, Laskshmi Waniganayke, Vivien Mai, Rabiya Atif, Lakshmi Wa, Sapna Maharaj, David Liong, Christine Matic, Katherine Tran, Sheenal Jas, Danielle Gibbs, Sanj Wickremasinghe, Robyn Guymer, Lyndell Lim, Sukhpal Sandhu, Thanh Nguyen, Dania Qatarneh, Hessom Razavi, Elaine Chong, Matthew Little, Gaurav Bhardwau, Michael Ayres, Michael Chen, Daini Ong, Katarina Creese, Tricia Drew, Carly D'Sylva Parfett, Tanya Pejnovic, Thuy Chau, Sutha Sanmugasundram, Maria Kolic, Elizabeth Glatz, Tina-Marie Tonder, Alan Luckie, Stephen Heery, Timothy Steele, Jennifer Arnold, Bryan Matthews, Julie Croft, Alex Breen, Bronwyn Gabriel, Maegan Anderson, Michelle Dodds, Marcus Dwyer, Bev Brown, Jacinta Dwyer, Ivan Fu, Helen Macauley, James Wong, Rajeev Chalasani, Charmaine Lim, Son Huynh, Timothy Nolan, James Leong, Kit Lau, Swas Kumar, Trang Nguyen, Joseph Bitar, Hannah Ahern, Arooj Ali, Nuria Zamora, Angela Lai, Randa Moussa, Carmen Do, Nitin Verma, Guy Bylsma, Andrew Traill, Beverley Curry, Amy Paprotny, Alfonso Ayesa, Alyse Johns, Zanobia Ujjainwala, Andrew Maver, Derek Chan, John Chang, Hyong Kwon Kang, Gavin Stringfellow, Terence Tan, Helen Cass, Trish Forsyth, Anh Nguyen, Angela Chung, Harriette Ayson, Catherine Severino, Caroline Chahine, Lara Collis, Anita Cristy, Mona Mohmodian, Selina Webb, Muradiya Payir, Mara Garibaldi, Trazia Mekhail, Brendan Vote, Tze'Yo Toh, Nima Pakrou, Jennie Rossetto, Shannon Harris, Rachael Adams, Rachael Groves, Maddie Johns, Kristie Richards, Eliza Jenkins, Natalie Daley, James Baker, Mark Gorbatov, Lavaniya Rajanayagam, Ludmila Jitskaia, Jenny Xie, Anthony Nguyen, Ian McAllister, Fred Chen, Tim Isaacs, Tracey-Anne Dickens, Rachel Matthews, Amelia Jason, Ivy Tang, Gareth Lingham, Holly Brown, Alla Soloshenko, Max Cuypers, Anne McSweeney, Jolly Gilhotra, Shane Durkin, James Muecke, Kerin Haywood, Cathy Brko, Rinty Vincent, Carolyn Luscombe, Alex Hunyor, Christine Younan, Robert Chong, Rohan Merani, Adrian Fung, I-Van Ho, Gerald Liew, Vinnci Lee, Gerald Chan, Sarah Liu, Tharini Ganess, Susanthy Rajasundaran, Maryam Sadat, Godfrey Quin, Stephen Ong, Claire Hooper, Vivien Dihn, Ward Al-Ghurani, Sally Ngai, Maria Choi, Gordana Tisma, Anton Van Heerden, Anthony Hall, Kira Michalova, Natalie Coleman, Allanah Price, Mercy Nguyen, Clodia Hanna, Camille Collins, Elaina Dickeson, Annie Lee, Mela Bilyk, Theresa Lee, John Downie, Naggi Assaad, Leanne Cooper, Catherine Le, Amanda Armanssen, Zena Khalil

المصدر: Ophthalmology. 126:723-734

مصطلحات موضوعية: medicine.medical_specialty, Visual acuity, genetic structures, Bevacizumab, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Ophthalmology, Medicine, Prospective cohort study, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, business.industry, Retrospective cohort study, Macular degeneration, Fluorescein angiography, medicine.disease, 030221 ophthalmology & optometry, medicine.symptom, Ranibizumab, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f4e58757b22fd68b8620ac18ddf7063
https://doi.org/10.1016/j.ophtha.2018.11.025

المؤلفون: Han Feng, Xiaohong Zhao, Jenny Xie, Xue Bai, Weiwei Fu, Hairong Chen, Hong Tang, Xiaohu Wang, Chen Dong

المصدر: Science China. Life sciences. 65(6)

مصطلحات موضوعية: Mice, T Follicular Helper Cells, Influenza, Human, Animals, Cytokines, Humans, Cell Differentiation, T-Lymphocytes, Helper-Inducer, General Agricultural and Biological Sciences, Germinal Center, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, General Environmental Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee230825880088479fa944a67789298
https://pubmed.ncbi.nlm.nih.gov/35258743

المؤلفون: Yu Feng, Liguo Liu, Jing Li, Jia Huang, Jenny Xie, Laurence Menard, Yanfen Shi, Xiaohong Zhao, Shan Xie, Wenjuan Zang, Haidong Tan, Zhiying Yang, Ling Ni

المصدر: Oncology Reports

مصطلحات موضوعية: Adult, Aged, 80 and over, Male, Cancer Research, B-Lymphocytes, China, B cells, Carcinoma, Hepatocellular, antitumor immunity, Liver Neoplasms, General Medicine, Articles, hepatocellular carcinoma, Middle Aged, Oncology, programmed cell death protein-1/programmed death ligand-1, Tumor Microenvironment, Humans, Female, immunotherapy, HCC, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7516082c77de0ddd784526e03445c53
https://pubmed.ncbi.nlm.nih.gov/34958112

المؤلفون: John L. Gilmore, Hai-Yun Xiao, T. G. Murali Dhar, Michael Yang, Zili Xiao, Xiaoxia Yang, Tracy L. Taylor, Kim W. McIntyre, Bethanne M. Warrack, Hong Shi, Paul C. Levesque, Anthony M. Marino, Georgia Cornelius, Arvind Mathur, Ding Ren Shen, Jian Pang, Mary Ellen Cvijic, Lois D. Lehman-McKeeman, Huadong Sun, Jenny Xie, Luisa Salter-Cid, Percy H. Carter, Alaric J. Dyckman

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, S 1P 1 modulator BMS -986104, sphingosine -1-phosphate G-protein-, PK, Exploring Side Chain Modifications, alkyl side chain, PD, S 1P 1, Bicyclic Ligand-Biased Agonists, Safety Profiles Sphingosine -1-phos, phosphate metabolite, S 1P receptors, S 1P, envir, psy

Relation: https://doi.org/10.1021/acs.jmedchem.0c01109.s002

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01109.s002