المؤلفون: Yauheniya Cherkas, Michael K. McMillian, Dhammika Amaratunga, Nandini Raghavan, Jennifer C. Sasaki

المصدر: Toxicology Reports, Vol 3, Iss , Pp 252-261 (2016)

مصطلحات موضوعية: Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750016300099; https://doaj.org/toc/2214-7500

URL الوصول: https://doaj.org/article/aad297a1c8d14f82ab1844ff388aea3c

المؤلفون: Véronique Thybaud, Kerry L. Dearfield, Roland Froetschl, Jennifer C. Sasaki, Mirjam Luijten, George E. Johnson, John Nicolette, Michelle R. Embry, Laura Custer, Gladys Ouedraogo, Raja S. Settivari

المصدر: Environmental and Molecular Mutagenesis. 62:512-525

مصطلحات موضوعية: Pharmaceutical drug, Epidemiology, Health, Toxicology and Mutagenesis, Health authority, media_common.quotation_subject, medicine.medical_treatment, Genomics, Antineoplastic Agents, Phytogenic, Risk analysis (engineering), medicine, Animals, Humans, Quality (business), Technical committee, In patient, Genetics (clinical), Selection (genetic algorithm), Etoposide, DNA Damage, media_common, Genetic Toxicology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94a80d1984a7afa084ed6b9f60639c4
https://doi.org/10.1002/em.22467

المؤلفون: Danna Jennings, Sarah Huntwork-Rodriguez, Anastasia G. Henry, Jennifer C. Sasaki, René Meisner, Dolores Diaz, Hilda Solanoy, Xiang Wang, Elvira Negrou, Vitaliy V. Bondar, Rajarshi Ghosh, Michael T. Maloney, Nicholas E. Propson, Yuda Zhu, Romeo D. Maciuca, Laura Harris, Angela Kay, Peter LeWitt, T. Alex King, Drew Kern, Aaron Ellenbogen, Ira Goodman, Andrew Siderowf, Jason Aldred, Omid Omidvar, Shababa T. Masoud, Sonnet S. Davis, Annie Arguello, Anthony A. Estrada, Javier de Vicente, Zachary K. Sweeney, Giuseppe Astarita, Marie T. Borin, Bradley K. Wong, Harvey Wong, Hoang Nguyen, Kimberly Scearce-Levie, Carole Ho, Matthew D. Troyer

المصدر: Science Translational Medicine. 14

مصطلحات موضوعية: Mice, Mutation, Animals, Humans, Parkinson Disease, General Medicine, Phosphorylation, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d447b718b56152fa35afc4ad299bcf
https://doi.org/10.1126/scitranslmed.abj2658

المؤلفون: John Nicolette, Donald P. Quigley, Alejandra Trejo-Martin, David Woolley, Lidiya Stavitskaya, Lennart T. Anger, Dave Bower, Jennifer C. Sasaki, Candice Y. Johnson, Michelle O. Kenyon, Glenn J. Myatt, Sandy Weiner, Naomi L. Kruhlak, Susanne Glowienke, Véronique Gervais, Lisa Beilke, Angela White, Penny Leavitt, Roxanne Andaya, James Harvey, Joel P. Bercu, Andrew Teasdale, Jacky Van Gompel, Raymond Kemper, Kevin P. Cross, Scott Miller, Catrin Hasselgren, Barber Christopher Gordon, M. Vijayaraj Reddy, Joerg Wichard, Robert A. Jolly, Alessandro Brigo, Dennie S. Welch, Alexander Amberg, Russell Naven, Masamitsu Honma, Alexis Parenty, Stephen Gomez, Zoryanna Cammerer, Mark Powley, Laura Custer, Krista L. Dobo, Helga Gerets, Wolfgang Muster

المصدر: Regulatory toxicology and pharmacology : RTP

مصطلحات موضوعية: Drug Industry, Process (engineering), Computer science, Quantitative Structure-Activity Relationship, Guidelines as Topic, 010501 environmental sciences, Toxicology, computer.software_genre, Risk Assessment, 030226 pharmacology & pharmacy, 01 natural sciences, Article, Domain (software engineering), 03 medical and health sciences, Government Agencies, 0302 clinical medicine, Drug industry, 0105 earth and related environmental sciences, fungi, General Medicine, Drug product, Data mining, Drug Contamination, Indeterminate, computer, Mutagens, Applicability domain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc40f205a6b475a7fdd8889147e338e1
https://doi.org/10.1016/j.yrtph.2018.12.007

المؤلفون: Steven M. Bryce, Laura Custer, Kerry L. Dearfield, Carole L. Yauk, Giel Hendriks, Ashley Allemang, Sheila M. Galloway, Maik Schuler, Stefan Pfuhler, Patricia A Escobar, Azeddine Elhajouji, Gladys Ouedraogo, Albert J. Fornace, Heng-Hong Li, Jennifer C. Sasaki, Daniel J Roberts, Yasmin Dietz, Ulrike Hemmann, Jan van Benthem, Véronique Thybaud, Roland Froetschl, Lauren Peel, Mirjam Luijten

مصطلحات موضوعية: Epidemiology, Health, Toxicology and Mutagenesis, Population, Computational biology, 010501 environmental sciences, 01 natural sciences, Tubulin binding, 03 medical and health sciences, mode of action, Adverse Outcome Pathway, Animals, Humans, Mode of action, education, Genetics (clinical), Organism, 030304 developmental biology, 0105 earth and related environmental sciences, Aurora Kinase A, 0303 health sciences, education.field_of_study, Adverse Outcome Pathways, Mutagenicity Tests, genotoxicity, Chromosome Breakage, Aneuploidy, adverse outcome pathway, Mutation, Biological plausibility, Chromosome breakage, Genetic Toxicology, DNA Damage, Mutagens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94120698a05b8acf2acfae209b20a2b1
http://hdl.handle.net/10029/623463

المؤلفون: Harish Shankaran, Abhishek G. Sathe, Jennifer C. Sasaki, Aixiang Xue, Per E. Andrén, Selvi Pradeepan, Anna Nilsson, Richard J. A. Goodwin, Natalie Keirstead, Anshul Gupta, Richard T. Gallagher, John G. Swales

المصدر: Chemical Research in Toxicology. 28:1823-1830

مصطلحات موضوعية: Male, Spectrometry, Mass, Electrospray Ionization, Chemistry, medicine.drug_class, Polymyxin B1, Metabolite, Polymyxin, General Medicine, Pharmacology, Kidney, Toxicology, Mass spectrometry imaging, Rats, Nephrotoxicity, chemistry.chemical_compound, Colistin, medicine, Animals, lipids (amino acids, peptides, and proteins), Polymyxins, Rats, Wistar, Drug metabolism, Polymyxin B, Chromatography, Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6815c5fe363edb205bfddb745649e05
https://doi.org/10.1021/acs.chemrestox.5b00262

المؤلفون: Marie Blais, Douglas Ferguson, Mark Pietras, Jim Fikes, Abhishek G. Sathe, Sally A. Price, Anshul Gupta, Melanie Galvin, Michael R. Hale, Robert L. Walsky, Yvonne P. Dragan, Frank McGrath, Crystal Brown, Paul J. Ciaccio, Gunther Kern, Matthew Wagoner, Letitia Cheatham, Nakpangi Johnson, Patricia Bentley, Natalie Keirstead, Debra Snow, Wenli Luo, Jennifer C. Sasaki

المصدر: Toxicological Sciences. 137:278-291

مصطلحات موضوعية: Male, medicine.medical_specialty, Cell Survival, medicine.drug_class, Polymyxin, Pharmacology, Toxicology, Cell Line, Nephrotoxicity, medicine, Animals, Rats, Wistar, Intensive care medicine, Blood urea nitrogen, Polymyxin B, Kidney, Dose-Response Relationship, Drug, Colistin, business.industry, Acute kidney injury, Prognosis, medicine.disease, Anti-Bacterial Agents, Rats, Early Diagnosis, medicine.anatomical_structure, Data Interpretation, Statistical, Biomarker (medicine), Kidney Diseases, business, Biomarkers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e7ce12b5cc757b27009c075c2c9b9d
https://doi.org/10.1093/toxsci/kft247

المؤلفون: Wim Bert Griet Schepens, Judith Eva Baumeister, Tim H. M. Jonckers, Geerwin Yvonne Paul Haché, Sabine Hallenberger, Marie-Claude Rouan, Jennifer C. Sasaki

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4998-5002

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Pharmacokinetics, Amide, Drug Discovery, medicine, Animals, Cytochrome P-450 CYP3A, Humans, HIV Protease Inhibitor, Benzothiazoles, Molecular Biology, ADME, Benzoxazoles, CYP3A4, Organic Chemistry, HIV Protease Inhibitors, Benzoxazole, Amides, Rats, chemistry, Benzothiazole, HIV-1, Cytochrome P-450 CYP3A Inhibitors, Molecular Medicine, Ritonavir, Caco-2 Cells, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2d88d0d5d3ea91fb98899e19d056b0
https://doi.org/10.1016/j.bmcl.2012.06.022

المؤلفون: Jennifer C. Sasaki, Monica Seger, James H. Kim, Louise Parks Saldutti, Robert E. Chapin, Brian P. Enright, Keith Jarvi, David Gregory Hall, Mary L. Hixon, Jeffrey S. Moffit, William J. Breslin, Terri Mitchard

المصدر: Birth Defects Research Part B: Developmental and Reproductive Toxicology. 92:511-525

مصطلحات موضوعية: Male, Embryology, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Health, Toxicology and Mutagenesis, Drug Evaluation, Preclinical, MEDLINE, Pharmacology, Toxicology, Testis, Toxicity Tests, medicine, Animals, Humans, Intensive care medicine, business.industry, Incidence (epidemiology), Confounding, Omics, Clinical trial, Pharmaceutical Preparations, Drug development, Drug Design, Biomarker (medicine), Testicular toxicity, business, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc543787a7276fd3f89d203d2dd4c7f
https://doi.org/10.1002/bdrb.20338

المؤلفون: Paul Van Hummelen, Jennifer C. Sasaki

المصدر: Mutation Research/Reviews in Mutation Research. 705:165-171

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Drug Evaluation, Preclinical, Genomics, Context (language use), Biology, Toxicology, Toxicogenetics, Human health, Genetics, Animals, Combinatorial Chemistry Techniques, Humans, Technology, Pharmaceutical, Drug discovery, Gene Expression Profiling, fungi, food and beverages, Data interpretation, Preclinical data, Drug development, Drug Design, Carcinogens, Toxicogenomics, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3785e6993b93238568ae99e4840c63c
https://doi.org/10.1016/j.mrrev.2010.04.007

المؤلفون: Jan van Benthem, David Jacobson-Kram, Véronique Thybaud, Masamitsu Honma, Rosalie K. Elespuru, Richard M. Walmsley, Jiri Aubrecht, Russell T. Naven, Stephen D. Dertinger, Paul D. White, George R. Douglas, Jennifer C. Sasaki, Marilyn J. Aardema, R. Daniel Benz, Albert J. Fornace, Marlies De Boeck, Patricia A. Escobar, Anthony M. Lynch, Eiji Yamamura, Robert H. Schiestl, James H. Kim, James F. Rusling

المصدر: Environmental and Molecular Mutagenesis. 52:205-223

مصطلحات موضوعية: Technology, Weight of evidence, Mutagenicity Tests, Epidemiology, business.industry, Emerging technologies, Consensus Development Conferences as Topic, International Cooperation, Health, Toxicology and Mutagenesis, Risk Assessment, Hazard, Chromosome aberration, Biotechnology, Genotoxicity testing, Engineering management, Animals, Humans, Workgroup, business, Risk assessment, Genetics (clinical), Mutagens, Genetic Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b881580e5ed072abe6e0faea67f8c4
https://doi.org/10.1002/em.20614

المؤلفون: Kim Martea, Gunther Kern, Harish Shankaran, Michael R. Hale, John G. Swales, Tyler Grebe, Anshul Gupta, Natalie Keirstead, Richard J. A. Goodwin, Jennifer C. Sasaki, Nakpangi Johnson, Aixiang Xue

المصدر: The FASEB Journal. 29

مصطلحات موضوعية: business.industry, medicine.drug_class, Polymyxin, Toxicity, Genetics, Medicine, Toxicokinetics, Pharmacology, business, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15ec24998ca44caeb8a202c40228db2c
https://doi.org/10.1096/fasebj.29.1_supplement.779.6

المؤلفون: Michael E. Colvin, Raymond S Fellers, Jennifer C. Sasaki

المصدر: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. :79-89

مصطلحات موضوعية: Free Radicals, Health, Toxicology and Mutagenesis, Ab initio, In Vitro Techniques, Hückel method, Catalysis, Electron Transport, DNA Adducts, Electron transfer, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Computational chemistry, 2-Naphthylamine, Genetics, Humans, Molecular Biology, chemistry.chemical_classification, Fluorenes, Aryl, Aromatic amine, Charge density, Models, Theoretical, Monooxygenase, 1-Naphthylamine, Enzyme, chemistry, Carcinogens, Microsomes, Liver, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d34c93832d491d300b712761fb86f9f
https://doi.org/10.1016/s0027-5107(02)00154-9

المؤلفون: Jennifer C Sasaki, Janet Arey, Patricia T Phousongphouang, David A. Eastmond, Karyn K. Parks, Andrew J. Grosovsky

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 445:113-125

مصطلحات موضوعية: Hypoxanthine Phosphoribosyltransferase, Health, Toxicology and Mutagenesis, Naphthalenes, Biology, medicine.disease_cause, Thymidine Kinase, Isozyme, Cell Line, 2-Naphthylamine, Genetics, medicine, Humans, Lymphocytes, Epoxide hydrolase, Micronuclei, Chromosome-Defective, Micronucleus Tests, Dose-Response Relationship, Drug, Mutagenicity Tests, Transfection, Monooxygenase, Biochemistry, Mutagenesis, Hypoxanthine-guanine phosphoribosyltransferase, Cell culture, Thymidine kinase, Carcinogens, Oxidation-Reduction, Genotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22081d56fb3b974f03aa15c0c78276a2
https://doi.org/10.1016/s1383-5718(99)00118-7

المؤلفون: Michael E. Colvin, Jennifer C. Sasaki, Ngoc L. Tran

المصدر: Current Pharmaceutical Design. 5:645-663

مصطلحات موضوعية: Pharmacology, Drug Discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad066f30f2ac972cece5bc0be3bae71b
https://doi.org/10.2174/1381612805666230110215849

المؤلفون: Eric S. C. Kwok, Sara M. Aschmann, Roger Atkinson, Jennifer C Sasaki, Janet Arey

المصدر: Environmental Science & Technology. 31:3173-3179

مصطلحات موضوعية: chemistry.chemical_classification, Reaction mechanism, Chemistry, Radical, Polycyclic aromatic hydrocarbon, General Chemistry, Photochemistry, Mass spectrometry, Chemical reaction, law.invention, chemistry.chemical_compound, Hydrocarbon, law, Environmental Chemistry, Organic chemistry, Flame ionization detector, Naphthalene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bdbb26dc926fb4e858ccba091ce29ac2
https://doi.org/10.1021/es9701523

المؤلفون: Sarah N. Campion, Hanry Yu, William J. Breslin, Bruce K. Beyer, Aldert H. Piersma, Louise Parks Saldutti, Jennifer C. Sasaki, William Kelce, Robert E. Chapin, Katie J. Turner, Paul M. D. Foster, Xiaozhong Yu, James H. Kim, Elaine M. Faustman, David Seyler, Terry R. Brown, Brian P. Enright, Thomas Hartung, Elizabeth G. Loboa

المصدر: ALTEX. 30(3)

مصطلحات موضوعية: Pharmacology, Male, testicular toxicity, bioengineering, biomedical engineering, in vitro screening, Drug-Related Side Effects and Adverse Reactions, Alternatives to animal testing, Cell Culture Techniques, General Medicine, Bioinformatics, Animal Testing Alternatives, Models, Biological, Medical Laboratory Technology, Predictive Value of Tests, ddc:570, Toxicity, Testis, Toxicity Tests, Testicular toxicity, Animals, Humans, Environmental Pollutants, Biomarkers, Cells, Cultured

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7ce27b23027275a240a0ecb36ae57d
https://pubmed.ncbi.nlm.nih.gov/23861079

المؤلفون: Jennifer C Sasaki, Janet Arey, Willam P. Harger

المصدر: Environmental Science & Technology. 29:1324-1335

مصطلحات موضوعية: chemistry.chemical_classification, endocrine system, Chromatography, Chemistry, fungi, Environmental chamber, Nitro compound, food and beverages, Mutagen, General Chemistry, medicine.disease_cause, High-performance liquid chromatography, Ames test, Environmental chemistry, polycyclic compounds, medicine, Environmental Chemistry, Bioassay, Gas chromatography, Quantitative analysis (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1757376f9d9fcf6df121a4a2c3a589
https://doi.org/10.1021/es00005a027

المؤلفون: Bram Van Dijck, Monica Singer, Ann Lampo, Jan Snoeys, Sandra De Jonghe, Kristel Steemans, Nancy Bogdan, Sofie Starckx, Jennifer C. Sasaki, Peggy Guzzie-Peck, Lieve Lammens, Ameesha Batheja, Jacky Van Gompel, Petra Vinken, Geert R. Verheyen

المصدر: Toxicologic pathology. 41(5)

مصطلحات موضوعية: Male, Propanols, Pharmacology, Naphthalenes, Toxicology, Pathology and Forensic Medicine, Rats, Sprague-Dawley, chemistry.chemical_compound, medicine, MiR-122, Toxicity Tests, Acute, Animals, Doxorubicin, Allyl alcohol, Molecular Biology, Acetaminophen, Liver injury, business.industry, Cell Biology, medicine.disease, Rats, MicroRNAs, chemistry, Liver, Isothiocyanate, Biomarker (medicine), Phenobarbital, Chemical and Drug Induced Liver Injury, business, Biomarkers, medicine.drug, Isocyanates

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f33a7ff6dc8562167e223b8ad7a8ede
https://pubmed.ncbi.nlm.nih.gov/23143187

المؤلفون: Sandy K. Weiner, Peggy Guzzie-Peck, Jennifer C. Sasaki and

مصطلحات موضوعية: Computational biology, Biology, Genetic Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7302552fe144edeb0eaa53bbdd7eceb6
https://doi.org/10.1002/9780470909911.ch8