المؤلفون: Anton Lindberg, Emily Murrell, Junchao Tong, N. Scott Mason, Daniel Sohn, Johan Sandell, Peter Ström, Jeffrey S. Stehouwer, Brian J. Lopresti, Jenny Viklund, Samuel Svensson, Chester A. Mathis, Neil Vasdev

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/565281a593e843aeae917584e9015b15

المؤلفون: Brian J. Lopresti, N. Scott Mason, Laszlo Rakos, Anton Lindberg, Johan Sandell, William E. Klunk, Chester A. Mathis, Neil Vasdev, Daniel Sohn, Jeffrey S. Stehouwer, Ashley C Knight, April Radelet, Alexander Sandberg, Per Hammarström, Junchao Tong, Samuel P.S. Svensson

المصدر: ACS Chemical Neuroscience. 12:596-602

مصطلحات موضوعية: Brain uptake, Genetically modified mouse, 0303 health sciences, Physiology, Chemistry, Cognitive Neuroscience, Radiosynthesis, Standardized uptake value, Cell Biology, General Medicine, Human brain, Biochemistry, Molecular biology, In vitro, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, In vivo, medicine, Radioligand, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93ac8efd7517f2803edd4e060ec244db
https://doi.org/10.1021/acschemneuro.0c00801

المؤلفون: Brian J. Lopresti, Guo-feng Huang, William E. Klunk, Chester A. Mathis, Jeffrey S. Stehouwer, Milos D. Ikonomovic, Eric E. Abrahamson, Alberto L. Vazquez, N. Scott Mason

المصدر: Nucl Med Biol

مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Amyloid, Amyloid beta, Article, 030218 nuclear medicine & medical imaging, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, mental disorders, medicine, Radioligand, Animals, Radiology, Nuclear Medicine and imaging, Radioactive Tracers, biology, Chemistry, Amyloidosis, Brain, Human brain, medicine.disease, Congo red, Cerebral Amyloid Angiopathy, medicine.anatomical_structure, Positron-Emission Tomography, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Thioflavin, Cerebral amyloid angiopathy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2103317576b37ef8ffa7c576a8f28759
https://doi.org/10.1016/j.nucmedbio.2020.05.001

المؤلفون: Anton, Lindberg, Ashley C, Knight, Daniel, Sohn, Laszlo, Rakos, Junchao, Tong, April, Radelet, N Scott, Mason, Jeffrey S, Stehouwer, Brian J, Lopresti, William E, Klunk, Johan, Sandell, Alexander, Sandberg, Per, Hammarström, Samuel, Svensson, Chester A, Mathis, Neil, Vasdev

المصدر: ACS Chem Neurosci

مصطلحات موضوعية: Mice, Radiochemistry, Tauopathies, Positron-Emission Tomography, Animals, Brain, tau Proteins, Radiopharmaceuticals, Article, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::2a1e1c145f58314eb744adf59f1e2505
https://pubmed.ncbi.nlm.nih.gov/33497190

المؤلفون: Ronald J. Voll, Michael A. Wassef, Jeffrey S. Stehouwer, Clinton D. Kilts, Michael J. Owens, Chase H. Bourke, Susan J Plott, Mark M. Goodman, Matthew S. Birnbaum

المصدر: Bioorganic & Medicinal Chemistry. 28:115660

مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Crf1 receptor, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry, Alkyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a2ddcc57abd33d50b41facdb52689805
https://doi.org/10.1016/j.bmc.2020.115660

المؤلفون: Ronald J. Voll, Clinton D. Kilts, Jeffrey S. Stehouwer, Chase H. Bourke, Mark M. Goodman, Michael J. Owens

المصدر: Bioorganic & Medicinal Chemistry Letters. 25:5111-5114

مصطلحات موضوعية: Male, Fluorine Radioisotopes, Stereochemistry, Clinical Biochemistry, Aminopyridines, Pharmaceutical Science, Ligands, Heterocyclic Compounds, 2-Ring, Receptors, Corticotropin-Releasing Hormone, Biochemistry, Article, Cell Line, Corticotropin-releasing hormone receptor 1, chemistry.chemical_compound, Amide, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, Brain uptake, Organic Chemistry, Crf1 receptor, Brain, Pet imaging, Peptide Fragments, Macaca fascicularis, chemistry, Positron-Emission Tomography, Pyrazines, Molecular Medicine, Radiopharmaceuticals

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9890c7d2dd35d3fbeb3de918257e52
https://doi.org/10.1016/j.bmcl.2015.10.010

المؤلفون: Mark M. Goodman, Jeffrey S. Stehouwer

المصدر: Tetrahedron Letters. 56:4480-4482

مصطلحات موضوعية: biology, medicine.diagnostic_test, Chemistry, Organic Chemistry, Biochemistry, Combinatorial chemistry, Article, Ion, Positron emission tomography, Drug Discovery, biology.protein, Nortropanes, medicine, Nuclear chemistry, Dopamine transporter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246017b0717a1b649443973392740c9f
https://doi.org/10.1016/j.tetlet.2015.05.100

المؤلفون: Mark M. Goodman, Jeffrey S. Stehouwer

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 56:114-119

مصطلحات موضوعية: biology, medicine.diagnostic_test, Chemistry, Serotonin reuptake inhibitor, Organic Chemistry, Tropane, Pet imaging, Pharmacology, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Positron emission tomography, Drug Discovery, biology.protein, medicine, Radiology, Nuclear Medicine and imaging, Spectroscopy, Serotonin transporter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90f74ada009bcc39db4a14dc1fe42cc4
https://doi.org/10.1002/jlcr.3011

المؤلفون: Vasiliki Michopoulos, Ronald J. Voll, John R. Votaw, Mark M. Goodman, Jiyoung Mun, Molly Embree, Mar M. Sanchez, Mark E. Wilson, Jeffrey S. Stehouwer

المصدر: Neuroscience. 228:83-100

مصطلحات موضوعية: medicine.medical_specialty, Genotype, Emotions, Hippocampus, Amygdala, Article, Internal medicine, medicine, Animals, Humans, Social Behavior, Anterior cingulate cortex, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Social stress, biology, General Neuroscience, Brain, Macaca mulatta, Dorsolateral prefrontal cortex, medicine.anatomical_structure, Endocrinology, Receptor, Serotonin, 5-HT1A, biology.protein, Female, Orbitofrontal cortex, Raphe nuclei, Psychology, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b90671493128cd25e3fa02cc4c7b358
https://doi.org/10.1016/j.neuroscience.2012.10.016

المؤلفون: Kelly P. Cosgrove, Andrei O. Koren, John Seibyl, Olivier Barret, Mark M. Goodman, David Alagille, Gilles Tamagnan, Jeffrey S. Stehouwer, Jeffery Batis

المصدر: Nuclear Medicine and Biology. 39:1137-1141

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Sertraline, biology, business.industry, Binding potential, Citalopram, Serotonergic, Bolus (medicine), Endocrinology, In vivo, Internal medicine, Radioligand, medicine, biology.protein, Molecular Medicine, Radiology, Nuclear Medicine and imaging, business, Serotonin transporter, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e795bd09cf0e5fabe4617702d7f0274a
https://doi.org/10.1016/j.nucmedbio.2012.07.006

المؤلفون: Jeffrey S. Stehouwer, Heather L. Kimmel, Ronald J. Voll, Leonard L. Howell, John R. Votaw, Mark M. Goodman, Frank I. Carroll, Jiyoung Mun, Jonathon A. Nye

المصدر: Synapse. 66:501-508

مصطلحات موضوعية: Male, Microdialysis, Dopamine, Dopamine Plasma Membrane Transport Proteins, Pharmacology, Article, Cellular and Molecular Neuroscience, Cocaine, Dopamine Uptake Inhibitors, parasitic diseases, mental disorders, medicine, Animals, Saimiri, Dopamine transporter, biology, Squirrel monkey, Brain, biology.organism_classification, Monoamine neurotransmitter, nervous system, Positron-Emission Tomography, Systemic administration, biology.protein, Extracellular Space, Psychology, Reinforcement, Psychology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1578c4c8f45f7b4e7287af15a06afc
https://doi.org/10.1002/syn.21536

المؤلفون: Jeffrey S. Stehouwer, Alice Nicol, Donald M. Hadley, Mark M. Goodman, Sally L. Pimlott, Gilles Tamagnan, Sue Champion, Rajeev Krishnadas

المصدر: European Journal of Nuclear Medicine and Molecular Imaging. 39:786-791

مصطلحات موضوعية: Biodistribution, biology, business.industry, Serotonin reuptake inhibitor, General Medicine, Spect imaging, Serotonin Plasma Membrane Transport Proteins, biology.protein, Radioligand, Medicine, Radiology, Nuclear Medicine and imaging, Serotonin, Nuclear medicine, business, Serotonin Uptake Inhibitors, Serotonin transporter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af9561d338c64280647a04ed790d43f4
https://doi.org/10.1007/s00259-011-2056-x

المؤلفون: Mark M. Goodman, John R. Votaw, Jeffrey S. Stehouwer, Thomas Wichmann, Rosa M. Villalba, Yoland Smith, Ronald J. Voll, Leonard L. Howell, Gunasingh J. Masilamoni

المصدر: Experimental Neurology. 226:265-273

مصطلحات موضوعية: Calbindins, Fluorine Radioisotopes, medicine.medical_specialty, Time Factors, Tyrosine 3-Monooxygenase, Nortropanes, Substantia nigra, Behavioral Symptoms, Striatum, Ligands, Midbrain, chemistry.chemical_compound, S100 Calcium Binding Protein G, Developmental Neuroscience, Dopamine, Internal medicine, Dopaminergic Cell, medicine, Animals, Dopamine transporter, Dopamine Plasma Membrane Transport Proteins, biology, Chemistry, MPTP, Dopaminergic, Brain, MPTP Poisoning, Reproducibility of Results, Macaca mulatta, Endocrinology, nervous system, Neurology, Positron-Emission Tomography, biology.protein, Autoradiography, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63d0278ca7904c6406cf9d9d509478e
https://doi.org/10.1016/j.expneurol.2010.08.024

المؤلفون: Ping Helen Chen, Lauryn M. Daniel, John R. Votaw, Michael J. Owens, Lawrence E. Williams, Jeffrey S. Stehouwer, Mark M. Goodman, Susan J Plott, Leonard L. Howell, Ronald J. Voll

المصدر: Journal of Medicinal Chemistry. 53:5549-5557

مصطلحات موضوعية: Fluorine Radioisotopes, medicine.medical_specialty, Nortropanes, Stereochemistry, Dopamine Plasma Membrane Transport Proteins, Caudate nucleus, chemistry.chemical_element, Ligands, Binding, Competitive, Article, Structure-Activity Relationship, Cerebellum, Internal medicine, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Dopamine transporter, medicine.diagnostic_test, biology, Chemistry, Putamen, Brain, Stereoisomerism, Macaca fascicularis, Endocrinology, nervous system, Positron emission tomography, Positron-Emission Tomography, Fluorine, biology.protein, Molecular Medicine, Caudate Nucleus, Radiopharmaceuticals, Preclinical imaging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c788930da864e17a1af9c201457a6635
https://doi.org/10.1021/jm100269c

المؤلفون: Heather L. Kimmel, Kristin M. Wilcox, John R. Votaw, S. Stevens Negus, Leonard L. Howell, Nancy K. Mello, Jeffrey S. Stehouwer, F. Ivy Carroll, Sarah B. Ewing, Mark M. Goodman

المصدر: Pharmacology Biochemistry and Behavior. 90:453-462

مصطلحات موضوعية: Male, Drug, Reinforcement Schedule, Substance-Related Disorders, media_common.quotation_subject, Clinical Biochemistry, Self Administration, Pharmacology, Toxicology, Biochemistry, Article, Behavioral Neuroscience, Discrimination, Psychological, Cocaine, Dopamine Uptake Inhibitors, Pharmacokinetics, Dopamine, medicine, Animals, Biological Psychiatry, media_common, Brain Chemistry, Dopamine Plasma Membrane Transport Proteins, Behavior, Animal, Dose-Response Relationship, Drug, Monoamine transporter, biology, Brain, Macaca mulatta, Phenyltropane, Monoamine neurotransmitter, Positron-Emission Tomography, Pharmacodynamics, biology.protein, Conditioning, Operant, Radiopharmaceuticals, Self-administration, Psychology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6a7d76b4118d3087f1595ed0cdc178
https://doi.org/10.1016/j.pbb.2008.03.032

المؤلفون: Michael J. Owens, Charles B. Nemeroff, Jeffrey S. Stehouwer, Nachwa Jarkas, Clinton D. Kilts, Fanxing Zeng, Mark M. Goodman, Ronald J. Voll

المصدر: Bioorganic & Medicinal Chemistry. 16:783-793

مصطلحات موضوعية: Primates, Fluorine Radioisotopes, Stereochemistry, Morpholines, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Radioligand Assay, Reboxetine, Drug Discovery, Radioligand, medicine, Animals, Humans, Carbon Radioisotopes, Molecular Biology, Fluoroethyl, Serotonin transporter, Dopamine transporter, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Norepinephrine Plasma Membrane Transport Proteins, Molecular Structure, biology, Chemistry, Organic Chemistry, Brain, Norepinephrine transporter, Positron-Emission Tomography, Vesicular Monoamine Transport Proteins, biology.protein, Molecular Medicine, Radiopharmaceuticals, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef974358ddf53d1cb1f595a219f56ca2
https://doi.org/10.1016/j.bmc.2007.10.025

المؤلفون: Jeffrey S. Stehouwer, Mark M. Goodman

المصدر: ChemInform. 46

مصطلحات موضوعية: Chemistry, General Medicine, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::97fe305e9af67440077276549e0e14ae
https://doi.org/10.1002/chin.201544078

المؤلفون: Chase H. Bourke, Jeffrey S. Stehouwer, Susan J Plott, Ronald J. Voll, Michael A. Wassef, Clinton D. Kilts, Michael J. Owens, Mark M. Goodman, Matthew S. Birnbaum

المصدر: Bioorganicmedicinal chemistry. 23(15)

مصطلحات موضوعية: Male, Fluorine Radioisotopes, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Chemistry Techniques, Synthetic, Ligands, Biochemistry, Binding, Competitive, Receptors, Corticotropin-Releasing Hormone, Article, Corticotropin-releasing hormone receptor 1, Rats, Sprague-Dawley, chemistry.chemical_compound, Diagnostic Uses of Chemicals, Drug Discovery, PEG ratio, medicine, Animals, Humans, Receptor, Molecular Biology, Alkyl, chemistry.chemical_classification, Chemistry, Organic Chemistry, Crf1 receptor, Anatomy, In vitro, Macaca fascicularis, medicine.anatomical_structure, Isotope Labeling, Positron-Emission Tomography, Molecular Medicine, Bone marrow, Radiopharmaceuticals, Fluoride

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9877d13242d3b3db1c781aec793332ca
https://pubmed.ncbi.nlm.nih.gov/32747078

المؤلفون: Nachwa Jarkas, Eugene J. Malveaux, Michael J. Owens, Vernon M. Camp, Leonard L. Howell, Ronald Voll, Jeffrey S. Stehouwer, Mark M. Goodman, Larry A Williams, John Votaw, Fanxing Zeng

المصدر: Journal of Medicinal Chemistry. 49:6760-6767

مصطلحات موضوعية: Nortropanes, Stereochemistry, Ligands, Binding, Competitive, Radioligand Assay, Structure-Activity Relationship, In vivo, Drug Discovery, Radioligand, Animals, Humans, Carbon Radioisotopes, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Norepinephrine Plasma Membrane Transport Proteins, biology, Chemistry, Radiosynthesis, Brain, Stereoisomerism, Macaca fascicularis, Isotope Labeling, Positron-Emission Tomography, biology.protein, Molecular Medicine, Serotonin, Radiopharmaceuticals, Preclinical imaging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8262054a723f8ab7c26918a6601a8a6f
https://doi.org/10.1021/jm060641q

المؤلفون: Nachwa Jarkas, John R. Votaw, Ronald J. Voll, Mark M. Goodman, Laurent Martarello, Fanxing Zeng, Jeffrey S. Stehouwer, Gilles Tamagnan, Lawrence E. Williams, Christophe Plisson

المصدر: Journal of Medicinal Chemistry. 48:7080-7083

مصطلحات موضوعية: Fluorine Radioisotopes, Nortropanes, Stereochemistry, Ligands, Binding, Competitive, Cell Line, Radioligand Assay, Structure-Activity Relationship, In vivo, Drug Discovery, Radioligand, Animals, Humans, Carbon Radioisotopes, Furans, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Norepinephrine Plasma Membrane Transport Proteins, biology, Bicyclic molecule, Chemistry, Radiosynthesis, Brain, Ligand (biochemistry), Macaca mulatta, Macaca fascicularis, Positron-Emission Tomography, biology.protein, Molecular Medicine, Radiopharmaceuticals, Preclinical imaging, Tropanes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0a1cbaaa3c144735192c07d7ba08ff
https://doi.org/10.1021/jm0504095