المؤلفون: Gédéon Prince Manouana, Elangwe-Milo Sarah-Matio, Fanny Hellhammer, Julien Zahouli Bi Zahouli, Aurélien Sery Bahi Tapé, Yasmine Nandy Biré, Jean-Denis Kacou Dibo, Guiéno Edwige Houriaaidji, Gaël Darren Maganga, Jumafra Perside Koumba, Jeannot Frejus Zinsou, Grace Cherile Ongouta-Mafia, Terence Stravensky Boussougou-Sambe, Luc Salako Djogbenou, Adandé Medjigbodo, Oswald Djihinto, Jacques F. Mavoungou, Rodrigue Mintsa-Nguema, Ayola Akim Adegnika, Steffen Borrmann, Stefanie C. Becker

المصدر: Frontiers in Tropical Diseases, Vol 5 (2024)

مصطلحات موضوعية: arbovirus, vector, Benin, Gabon, Côte d’Ivoire, Arctic medicine. Tropical medicine, RC955-962

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fitd.2024.1355778/full; https://doaj.org/toc/2673-7515

URL الوصول: https://doaj.org/article/2a1af70fe5c94ecc8fc090d1ecc3e404

المؤلفون: Gédéon Prince Manouana, Eva Lorenz, Mirabeau Mbong Ngwese, Paul Alvyn Nguema Moure, Oumou Maiga Ascofaré, Charity Wiafe Akenten, John Amuasi, Njari Rakotozandrindrainy, Raphael Rakotozandrindrainy, Joyce Mbwana, John Lusingu, Natalie Byrne, Sophia Melhem, Jeannot Frejus Zinsou, Roméo Bayodé Adegbite, Benedikt Hogan, Doris Winter, Jurgen May, Peter Gottfried Kremsner, Steffen Borrmann, Daniel Eibach, Ayola Akim Adegnika

المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008448 (2020)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/d8d3df87bcda4d09bb6598f72e32b512

المؤلفون: Sèyigbéna P. Déo‑Gracias Berry, Yabo Josiane Honkpèhedji, Esther Ludwig, Saïdou Mahmoudou, Ulrich Fabien Prodjinotho, Rafiou Adamou, Odilon P. Nouatin, Bayode R. Adégbitè, Jean Claude Dejon‑Agobe, Romuald Beh Mba, Moustapha Maloum, Anne Marie Mouima Nkoma, Jeannot Fréjus Zinsou, Adrian J. F. Luty, Meral Esen, Ayôla Akim Adégnika, Clarissa Prazeres da Costa

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-024-70356-z; https://doaj.org/toc/2045-2322; https://doaj.org/article/20d1f5ec7f5847e3b35395e2a14fa648

الاتاحة: https://doi.org/10.1038/s41598-024-70356-z
https://doaj.org/article/20d1f5ec7f5847e3b35395e2a14fa648

المؤلفون: Jean Ronald Edoa, Bayodé Roméo Adégbitè, Yabo Josiane Honkpéhèdji, Jeannot Fréjus Zinsou, Stravensky Térence Boussougou-Sambe, Tamirat Gebru Woldearegai, Benjamin Mordmüller, Ayola Akim Adegnika, Jean Claude Dejon‑Agobé

مصطلحات موضوعية: Medicine, Microbiology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Anthelminthic treatment, Ascaris lumbricoides, Epidemiology, Gabon, Hookworm, Incidence, Prevalence, Trichuris trichiura

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Epidemiology_of_soil-transmitted_helminth_infections_and_the_differential_effect_of_treatment_on_the_distribution_of_helminth_species_in_rural_areas_of_Gabon/24923737

الاتاحة: https://doi.org/10.6084/m9.figshare.24923737.v1
https://figshare.com/articles/journal_contribution/Additional_file_1_of_Epidemiology_of_soil-transmitted_helminth_infections_and_the_differential_effect_of_treatment_on_the_distribution_of_helminth_species_in_rural_areas_of_Gabon/24923737

المؤلفون: Sèyigbéna P. Déo-Gracias Berry, Yabo Josiane Honkpèhedji, Esther Ludwig, Saïdou Mahmoudou, Ulrich Fabien Prodjinotho, Rafiou Adamou, Odilon P. Nouatin, Bayode R. Adégbitè, Jean Claude Dejon-Agobe, Romuald Beh Mba, Moustapha Maloum, Anne Marie Mouima Nkoma, Jeannot Fréjus Zinsou, Adrian J. F. Luty, Meral Esen, Ayôla Akim Adégnika, Clarissa Prazeres da Costa

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Sub-Saharan Africa, Helminth infections, Maternal, Newborn vitamin D, Pregnancy outcomes, Medicine, Science

Relation: https://doi.org/10.1038/s41598-024-65232-9; https://doaj.org/toc/2045-2322; https://doaj.org/article/6bb17c4933f04848a88f15e24b97cd8e

الاتاحة: https://doi.org/10.1038/s41598-024-65232-9
https://doaj.org/article/6bb17c4933f04848a88f15e24b97cd8e

المؤلفون: Jean Ronald Edoa, Bayodé Roméo Adégbitè, Yabo Josiane Honkpéhèdji, Jeannot Fréjus Zinsou, Stravensky Térence Boussougou-Sambe, Tamirat Gebru Woldearegai, Benjamin Mordmüller, Ayola Akim Adegnika, Jean Claude Dejon‑Agobé

المصدر: Tropical Medicine and Health, Vol 52, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Anthelminthic treatment, Ascaris lumbricoides, Epidemiology, Gabon, Hookworm, Incidence, Arctic medicine. Tropical medicine, RC955-962

Relation: https://doi.org/10.1186/s41182-023-00567-z; https://doaj.org/toc/1349-4147; https://doaj.org/article/6e663c4d11eb46bf942b1682b1b208d9

الاتاحة: https://doi.org/10.1186/s41182-023-00567-z
https://doaj.org/article/6e663c4d11eb46bf942b1682b1b208d9

المؤلفون: Stravensky Térence Boussougou-Sambe, Tamirat Gebru Woldearegai, Ange Gatien Doumba-Ndalembouly, Barclaye Ngossanga, Romuald Beh Mba, Jean Ronald Edoa, Jeannot Fréjus Zinsou, Yabo Josiane Honkpehedji, Ulysse Ateba Ngoa, Jean Claude Dejon-Agobé, Steffen Borrmann, Peter G. Kremsner, Benjamin Mordmüller, Ayôla A. Adegnika

المصدر: Parasites & Vectors, Vol 15, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Anopheles gambiae complex, Plasmodium species, Entomological inoculation rate, Moyen Ogooué Province, Gabon, Infectious and parasitic diseases, RC109-216

Relation: https://doi.org/10.1186/s13071-022-05320-9; https://doaj.org/toc/1756-3305; https://doaj.org/article/1beebe6e5a94437dbc9ca14944a9319f

الاتاحة: https://doi.org/10.1186/s13071-022-05320-9
https://doaj.org/article/1beebe6e5a94437dbc9ca14944a9319f

المؤلفون: Jean Claude Dejon-Agobé (5598059), Jeannot Fréjus Zinsou (5598062), Yabo Josiane Honkpehedji (5598065), Jean Ronald Edoa (10881610), Bayodé Roméo Adegbité (11469157), Romuald Beh-Mba (11469160), Peter Gottfried Kremsner (8551122), Ayola Akim Adegnika (9034340), Martin Peter Grobusch (9287756)

مصطلحات موضوعية: Medicine, Ecology, Cancer, Science Policy, Knowledge, Attitude, Practice, Schistosomiasis, Risk-enhancing practices, Lambaréné, Gabon

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Knowledge_attitudes_and_practices_pertaining_to_urogenital_schistosomiasis_in_Lambar_n_and_surrounding_areas_Gabon/16664308

الاتاحة: https://doi.org/10.6084/m9.figshare.16664308.v1

المؤلفون: Jean Claude Dejon-Agobé (5598059), Jeannot Fréjus Zinsou (5598062), Yabo Josiane Honkpehedji (5598065), Jean Ronald Edoa (10881610), Bayodé Roméo Adegbité (11469157), Romuald Beh-Mba (11469160), Peter Gottfried Kremsner (8551122), Ayola Akim Adegnika (9034340), Martin Peter Grobusch (9287756)

مصطلحات موضوعية: Medicine, Ecology, Cancer, Science Policy, Knowledge, Attitude, Practice, Schistosomiasis, Risk-enhancing practices, Lambaréné, Gabon

Relation: https://figshare.com/articles/journal_contribution/Additional_file_2_of_Knowledge_attitudes_and_practices_pertaining_to_urogenital_schistosomiasis_in_Lambar_n_and_surrounding_areas_Gabon/16664311

الاتاحة: https://doi.org/10.6084/m9.figshare.16664311.v1

المؤلفون: Jean Claude Dejon-Agobé (5598059), Jeannot Fréjus Zinsou (5598062), Yabo Josiane Honkpehedji (5598065), Jean Ronald Edoa (10881610), Bayodé Roméo Adegbité (11469157), Romuald Beh-Mba (11469160), Peter Gottfried Kremsner (8551122), Ayola Akim Adegnika (9034340), Martin Peter Grobusch (9287756)

مصطلحات موضوعية: Medicine, Ecology, Cancer, Science Policy, Knowledge, Attitude, Practice, Schistosomiasis, Risk-enhancing practices, Lambaréné, Gabon

Relation: https://figshare.com/articles/journal_contribution/Additional_file_3_of_Knowledge_attitudes_and_practices_pertaining_to_urogenital_schistosomiasis_in_Lambar_n_and_surrounding_areas_Gabon/16664314

الاتاحة: https://doi.org/10.6084/m9.figshare.16664314.v1

المؤلفون: Jean Claude Dejon-Agobé (5598059), Jeannot Fréjus Zinsou (5598062), Yabo Josiane Honkpehedji (5598065), Jean Ronald Edoa (10881610), Bayodé Roméo Adegbité (11469157), Romuald Beh-Mba (11469160), Peter Gottfried Kremsner (8551122), Ayola Akim Adegnika (9034340), Martin Peter Grobusch (9287756)

مصطلحات موضوعية: Medicine, Ecology, Cancer, Science Policy, Knowledge, Attitude, Practice, Schistosomiasis, Risk-enhancing practices, Lambaréné, Gabon

Relation: https://figshare.com/articles/journal_contribution/Additional_file_4_of_Knowledge_attitudes_and_practices_pertaining_to_urogenital_schistosomiasis_in_Lambar_n_and_surrounding_areas_Gabon/16664317

الاتاحة: https://doi.org/10.6084/m9.figshare.16664317.v1

المؤلفون: Odilon Nouatin (828356), Juliana Boex Mengue (10906209), Jean Claude Dejon-Agobé (5598059), Rolf Fendel (211799), Javier Ibáñez (3450593), Ulysse Ateba Ngoa (10906212), Jean Ronald Edoa (10881610), Bayodé Roméo Adégbité (10906215), Yabo Josiane Honkpéhédji (10906218), Jeannot Fréjus Zinsou (5598062), Aurore Bouyoukou Hounkpatin (10906221), Kabirou Moutairou (828360), Andreas Homoet (10906224), Meral Esen (211790), Andrea Kreidenweiss (365793), Stephen L. Hoffman (10038985), Michael Theisen (81720), Adrian J. F. Luty (7910207), Bertrand Lell (224978), Selidji Todagbe Agnandji (3358820), Ghyslain Mombo-Ngoma (265164), Michael Ramharter (297552), Peter Kremsner (229101), Benjamin Mordmüller (211841), Ayôla Akim Adegnika (5598074)

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, CHMI, Total vaccine-specific IgG concentr., Vaccine-specific antibody concentra., 35 days, helminth infection, PCR, DVI, efficacy, polymerase chain reaction, falciparum, GLURP, Cationic Adjuvant Formulation, malaria-exposed adult volunteers, asexual blood-stage malaria vaccine., GMZ 2 adjuvanted, MSP, asexual blood-stage antigens, CAF, GMZ 2 malaria vaccine candidate, anti-GMZ 2 IgG concentration

Relation: https://figshare.com/articles/journal_contribution/PCR_mix_optimized_for_our_Study_/14713113

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361.s002

المؤلفون: Odilon Nouatin (828356), Juliana Boex Mengue (10906209), Jean Claude Dejon-Agobé (5598059), Rolf Fendel (211799), Javier Ibáñez (3450593), Ulysse Ateba Ngoa (10906212), Jean Ronald Edoa (10881610), Bayodé Roméo Adégbité (10906215), Yabo Josiane Honkpéhédji (10906218), Jeannot Fréjus Zinsou (5598062), Aurore Bouyoukou Hounkpatin (10906221), Kabirou Moutairou (828360), Andreas Homoet (10906224), Meral Esen (211790), Andrea Kreidenweiss (365793), Stephen L. Hoffman (10038985), Michael Theisen (81720), Adrian J. F. Luty (7910207), Bertrand Lell (224978), Selidji Todagbe Agnandji (3358820), Ghyslain Mombo-Ngoma (265164), Michael Ramharter (297552), Peter Kremsner (229101), Benjamin Mordmüller (211841), Ayôla Akim Adegnika (5598074)

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, CHMI, Total vaccine-specific IgG concentr., Vaccine-specific antibody concentra., 35 days, helminth infection, PCR, DVI, efficacy, polymerase chain reaction, falciparum, GLURP, Cationic Adjuvant Formulation, malaria-exposed adult volunteers, asexual blood-stage malaria vaccine., GMZ 2 adjuvanted, MSP, asexual blood-stage antigens, CAF, GMZ 2 malaria vaccine candidate, anti-GMZ 2 IgG concentration

Relation: https://figshare.com/articles/journal_contribution/Oligonucleotides_List_for_the_real_time_amplification_/14713110

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361.s001

المؤلفون: Odilon Nouatin (828356), Juliana Boex Mengue (10906209), Jean Claude Dejon-Agobé (5598059), Rolf Fendel (211799), Javier Ibáñez (3450593), Ulysse Ateba Ngoa (10906212), Jean Ronald Edoa (10881610), Bayodé Roméo Adégbité (10906215), Yabo Josiane Honkpéhédji (10906218), Jeannot Fréjus Zinsou (5598062), Aurore Bouyoukou Hounkpatin (10906221), Kabirou Moutairou (828360), Andreas Homoet (10906224), Meral Esen (211790), Andrea Kreidenweiss (365793), Stephen L. Hoffman (10038985), Michael Theisen (81720), Adrian J. F. Luty (7910207), Bertrand Lell (224978), Selidji Todagbe Agnandji (3358820), Ghyslain Mombo-Ngoma (265164), Michael Ramharter (297552), Peter Kremsner (229101), Benjamin Mordmüller (211841), Ayôla Akim Adegnika (5598074)

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, CHMI, Total vaccine-specific IgG concentr., Vaccine-specific antibody concentra., 35 days, helminth infection, PCR, DVI, efficacy, polymerase chain reaction, falciparum, GLURP, Cationic Adjuvant Formulation, malaria-exposed adult volunteers, asexual blood-stage malaria vaccine., GMZ 2 adjuvanted, MSP, asexual blood-stage antigens, CAF, GMZ 2 malaria vaccine candidate, anti-GMZ 2 IgG concentration

Relation: https://figshare.com/articles/journal_contribution/Distribution_of_helminth_species_in_the_helminth_co-infected_group_in_individuals_who_did_or_did_not_develop_malaria_following_CHMI_/14713122

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361.s004

المؤلفون: Odilon Nouatin (828356), Juliana Boex Mengue (10906209), Jean Claude Dejon-Agobé (5598059), Rolf Fendel (211799), Javier Ibáñez (3450593), Ulysse Ateba Ngoa (10906212), Jean Ronald Edoa (10881610), Bayodé Roméo Adégbité (10906215), Yabo Josiane Honkpéhédji (10906218), Jeannot Fréjus Zinsou (5598062), Aurore Bouyoukou Hounkpatin (10906221), Kabirou Moutairou (828360), Andreas Homoet (10906224), Meral Esen (211790), Andrea Kreidenweiss (365793), Stephen L. Hoffman (10038985), Michael Theisen (81720), Adrian J. F. Luty (7910207), Bertrand Lell (224978), Selidji Todagbe Agnandji (3358820), Ghyslain Mombo-Ngoma (265164), Michael Ramharter (297552), Peter Kremsner (229101), Benjamin Mordmüller (211841), Ayôla Akim Adegnika (5598074)

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, CHMI, Total vaccine-specific IgG concentr., Vaccine-specific antibody concentra., 35 days, helminth infection, PCR, DVI, efficacy, polymerase chain reaction, falciparum, GLURP, Cationic Adjuvant Formulation, malaria-exposed adult volunteers, asexual blood-stage malaria vaccine., GMZ 2 adjuvanted, MSP, asexual blood-stage antigens, CAF, GMZ 2 malaria vaccine candidate, anti-GMZ 2 IgG concentration

Relation: https://figshare.com/articles/journal_contribution/Proportion_of_helminth_species_in_coinfected_groups_at_D0_and_or_at_D84_/14713119

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361.s003

المؤلفون: Odilon Nouatin (828356), Juliana Boex Mengue (10906209), Jean Claude Dejon-Agobé (5598059), Rolf Fendel (211799), Javier Ibáñez (3450593), Ulysse Ateba Ngoa (10906212), Jean Ronald Edoa (10881610), Bayodé Roméo Adégbité (10906215), Yabo Josiane Honkpéhédji (10906218), Jeannot Fréjus Zinsou (5598062), Aurore Bouyoukou Hounkpatin (10906221), Kabirou Moutairou (828360), Andreas Homoet (10906224), Meral Esen (211790), Andrea Kreidenweiss (365793), Stephen L. Hoffman (10038985), Michael Theisen (81720), Adrian J. F. Luty (7910207), Bertrand Lell (224978), Selidji Todagbe Agnandji (3358820), Ghyslain Mombo-Ngoma (265164), Michael Ramharter (297552), Peter Kremsner (229101), Benjamin Mordmüller (211841), Ayôla Akim Adegnika (5598074)

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, CHMI, Total vaccine-specific IgG concentr., Vaccine-specific antibody concentra., 35 days, helminth infection, PCR, DVI, efficacy, polymerase chain reaction, falciparum, GLURP, Cationic Adjuvant Formulation, malaria-exposed adult volunteers, asexual blood-stage malaria vaccine., GMZ 2 adjuvanted, MSP, asexual blood-stage antigens, CAF, GMZ 2 malaria vaccine candidate, anti-GMZ 2 IgG concentration

Relation: https://figshare.com/articles/journal_contribution/_i_Schistosoma_haematobium_i_egg_counts_per_subject_in_infected_volunteers_/14713125

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361.s005

المؤلفون: Jean Claude Dejon Agobé, Henry Curtis Kariuki, Jeannot Fréjus Zinsou, Yabo Josiane Honkpehedji, Martin Peter Grobusch, Ayola Akim Adegnika

المصدر: Tropical Medicine and Infectious Disease; Volume 7; Issue 1; Pages: 1

مصطلحات موضوعية: schistosomiasis, Schistosoma haematobium, Gabon, Bulinus spp., cercarial shedding

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/tropicalmed7010001

الاتاحة: https://doi.org/10.3390/tropicalmed7010001

المؤلفون: Odilon Nouatin, Juliana Boex Mengue, Jean Claude Dejon-Agobé, Rolf Fendel, Javier Ibáñez, Ulysse Ateba Ngoa, Jean Ronald Edoa, Bayodé Roméo Adégbité, Yabo Josiane Honkpéhédji, Jeannot Fréjus Zinsou, Aurore Bouyoukou Hounkpatin, Kabirou Moutairou, Andreas Homoet, Meral Esen, Andrea Kreidenweiss, Stephen L Hoffman, Michael Theisen, Adrian J F Luty, Bertrand Lell, Selidji Todagbe Agnandji, Ghyslain Mombo-Ngoma, Michael Ramharter, Peter Kremsner, Benjamin Mordmüller, Ayôla Akim Adegnika

المصدر: PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009361 (2021)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

Relation: https://doi.org/10.1371/journal.pntd.0009361; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735; https://doaj.org/article/bb9e94c7a35042c8863884855ee8d7a3

الاتاحة: https://doi.org/10.1371/journal.pntd.0009361
https://doaj.org/article/bb9e94c7a35042c8863884855ee8d7a3

المؤلفون: Jean Claude Dejon-Agobé, Jeannot Fréjus Zinsou, Yabo Josiane Honkpehedji, Jean Ronald Edoa, Bayodé Roméo Adegbité, Romuald Beh-Mba, Peter Gottfried Kremsner, Ayola Akim Adegnika, Martin Peter Grobusch

المصدر: Parasites & Vectors, Vol 14, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Knowledge, Attitude, Practice, Schistosomiasis, Risk-enhancing practices, Lambaréné, Infectious and parasitic diseases, RC109-216

Relation: https://doi.org/10.1186/s13071-021-04905-0; https://doaj.org/toc/1756-3305; https://doaj.org/article/da20a274463c44d4b32a63959201e0df

الاتاحة: https://doi.org/10.1186/s13071-021-04905-0
https://doaj.org/article/da20a274463c44d4b32a63959201e0df

المؤلفون: Jean Claude Dejon-Agobé, Jean Ronald Edoa, Yabo Josiane Honkpehedji, Jeannot Fréjus Zinsou, Bayodé Roméo Adégbitè, Mirabeau Mbong Ngwese, Ance Mangaboula, Bertrand Lell, Tamirat Gebru Woldearegai, Martin Peter Grobusch, Benjamin Mordmüller, Ayôla Akim Adegnika

المصدر: Parasites & Vectors, Vol 14, Iss 1, Pp 1-1 (2021)

مصطلحات موضوعية: Infectious and parasitic diseases, RC109-216

Relation: https://doi.org/10.1186/s13071-021-04815-1; https://doaj.org/toc/1756-3305; https://doaj.org/article/e0031ecfc98341e78053dc27464d47c6

الاتاحة: https://doi.org/10.1186/s13071-021-04815-1
https://doaj.org/article/e0031ecfc98341e78053dc27464d47c6