المؤلفون: Sarah MacPherson, Sarah Keyes, Marisa K. Kilgour, Julian Smazynski, Vanessa Chan, Jessica Sudderth, Tim Turcotte, Adria Devlieger, Jessie Yu, Kimberly S. Huggler, Jason R. Cantor, Ralph J. DeBerardinis, Christopher Siatskas, Julian J. Lum

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 380-393 (2022)

مصطلحات موضوعية: T cell expansion, cell-based immunotherapy, culture media, phenotype, metabolism, 13C tracer analysis, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122000201; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/f33f2e28b0854ba7b43b89b360c06564

المؤلفون: Michael A. Leney-Greene, Arun K. Boddapati, Helen C. Su, Jason R. Cantor, Michael J. Lenardo

المصدر: iScience, Vol 23, Iss 1, Pp - (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004219305048; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/e825b6d6a754439592e615f1e91bba1e

المؤلفون: Kyle M. Flickinger, Jason R. Cantor

المصدر: The FASEB Journal. 36

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c60dd147cf18e2e856751fdd311de12e
https://doi.org/10.1096/fasebj.2022.36.s1.r3206

المؤلفون: Jason R. Cantor

المصدر: The FASEB Journal. 36

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10c931ef34bcdf00522aa32f190a96fd
https://doi.org/10.1096/fasebj.2022.36.s1.0i211

المؤلفون: Jason R. Cantor, Nicholas J. Rossiter, Kyle M Flickinger, Kimberly S. Huggler

المصدر: Methods in Molecular Biology ISBN: 9781071617199

مصطلحات موضوعية: Candidate gene, genomic DNA, education.field_of_study, Cas9, Population, RNA, CRISPR, Computational biology, Biology, education, Gene, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7ab3d9e4018e014205bbf38a4a8ea23a
https://doi.org/10.1007/978-1-0716-1720-5_2

المؤلفون: Kimberly S, Huggler, Nicholas J, Rossiter, Kyle M, Flickinger, Jason R, Cantor

المصدر: Methods in molecular biology (Clifton, N.J.). 2377

مصطلحات موضوعية: Genes, Essential, High-Throughput Nucleotide Sequencing, Humans, DNA, CRISPR-Cas Systems, Cell Line, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5076fe9020cb57f7551e013fc077c4fb
https://pubmed.ncbi.nlm.nih.gov/34709609

المؤلفون: Jason R. Cantor

المصدر: Trends Cell Biol

مصطلحات موضوعية: Cognitive science, 0303 health sciences, Human blood, Extramural, Cell Culture Techniques, Cell Biology, Biology, Article, Cell Line, Culture Media, Mice, Plasma, 03 medical and health sciences, 0302 clinical medicine, Plasma chemistry, Animals, Humans, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a4e89a45fe7395ab2d1cccc092cc96
https://doi.org/10.1016/j.tcb.2019.08.009

المؤلفون: Julian Smazynski, Kimberly S. Huggler, Jessica Sudderth, Adria Devlieger, Ralph J. DeBerardinis, Tim Turcotte, Marisa Kilgour, Christopher Siatskas, Sarah MacPherson, Sarah Keyes, Jason R. Cantor, Jessie Yu, Julian J. Lum

مصطلحات موضوعية: Glutamine, medicine.anatomical_structure, Chemistry, In vivo, medicine.medical_treatment, Glucose uptake, T cell, medicine, Immunotherapy, Metabolism, Phenotype, Ex vivo, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e4c1e9afdbfe1e024d7ee7e1bed12e8d
https://doi.org/10.1101/2021.08.24.457536

المؤلفون: Kelsey S. Williams, Russell G. Jones, Irem Kaymak, Jason R. Cantor

المصدر: Cancer Cell

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Tumor microenvironment, Stromal cell, Tumor cells, Cell Biology, Biology, Phenotype, Article, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immune system, Metabolomics, Oncology, 030220 oncology & carcinogenesis, Immune System, Neoplasms, Tumor Microenvironment, Animals, Humans, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edce6a55d6c5aeb341c30299167c8a6
https://europepmc.org/articles/PMC7837268/

المؤلفون: David M. Sabatini, Ross W. Soens, Nicholas J. Rossiter, Heather R. Keys, Charles H. Adelmann, Jason R. Cantor, Kimberly S. Huggler

المصدر: Cell Metab

مصطلحات موضوعية: 0301 basic medicine, Lineage (genetic), Physiology, Cancer, Cell Biology, Computational biology, Biology, medicine.disease, Phenotype, Article, Culture Media, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cell culture, Cell Line, Tumor, Genotype, medicine, CRISPR, Humans, CRISPR-Cas Systems, Molecular Biology, Gene, 030217 neurology & neurosurgery, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ee819f9dd1ec775d65d56f148f7d64
https://pubmed.ncbi.nlm.nih.gov/33651980

المؤلفون: Zhe Zhang, Gregory Stephanopoulos, Othon Iliopoulos, Woo Suk Ahn, David M. Sabatini, Wentao Dong, Jason R. Cantor

المصدر: AIChE Journal. 64:4289-4296

مصطلحات موضوعية: 0301 basic medicine, Environmental Engineering, Hypoxic tumor, Anabolism, biology, Chemistry, General Chemical Engineering, Hypoxia (medical), Pentose phosphate pathway, 03 medical and health sciences, 030104 developmental biology, Biochemistry, Anaerobic glycolysis, Cancer metabolism, biology.protein, medicine, medicine.symptom, Glyceraldehyde 3-phosphate dehydrogenase, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dadf60afea2d1e03c4480152badcd1da
https://doi.org/10.1002/aic.16423

المؤلفون: David M. Sabatini, Caroline A. Lewis, Elizaveta Freinkman, Tenzin Kunchok, Sze Ham Chan, Naama Kanarek, Lawrence D. Schweitzer, Jason R. Cantor, Heather R. Keys, Monther Abu-Remaileh

المصدر: Nature

مصطلحات موضوعية: Male, 0301 basic medicine, Ammonia-Lyases, Programmed cell death, Glutamate Formimidoyltransferase, Mice, SCID, Pharmacology, Article, Mice, Reduced Folate Carrier Protein, 03 medical and health sciences, Mice, Inbred NOD, In vivo, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Histidine, Tetrahydrofolates, chemistry.chemical_classification, Multidisciplinary, Nucleotides, Catabolism, Multifunctional Enzymes, Xenograft Model Antitumor Assays, 3. Good health, Tetrahydrofolate Dehydrogenase, Methotrexate, 030104 developmental biology, Enzyme, chemistry, Cell culture, Cancer cell, Folic Acid Antagonists, Female, CRISPR-Cas Systems, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bde0c880744c367010503f6e4817098
https://doi.org/10.1038/s41586-018-0316-7

المؤلفون: Arun K. Boddapati, Michael Alexander Leney-Greene, Jason R. Cantor, Michael J. Lenardo, Helen C. Su

المصدر: iScience, Vol 23, Iss 1, Pp-(2020)
iScience

مصطلحات موضوعية: 0301 basic medicine, Cell physiology, T cell, Immunology, chemistry.chemical_element, 02 engineering and technology, Calcium, Article, 03 medical and health sciences, Immune system, In vivo, Immunity, medicine, lcsh:Science, Biological sciences, Multidisciplinary, Immunological Methods, Chemistry, Biological Sciences, equipment and supplies, 021001 nanoscience & nanotechnology, T-lymphocyte activation, In vitro, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Human plasma, Antigen stimulation, lcsh:Q, 0210 nano-technology, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4c49ceb3520ab8798c7db33f2a249c
https://doi.org/10.1101/740845

المؤلفون: David M. Sabatini, Sonia M. Scaria, Kuang Shen, Rachel L. Wolfson, Robert A. Saxton, Lynne Chantranupong, Jason R. Cantor

المصدر: Science. 351:43-48

مصطلحات موضوعية: 0301 basic medicine, GTPase-activating protein, Guanosine, GTPase, mTORC1, Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Leucine, Humans, Protein kinase A, chemistry.chemical_classification, Multidisciplinary, TOR Serine-Threonine Kinases, GTPase-Activating Proteins, Nuclear Proteins, Proteins, Amino acid, 030104 developmental biology, chemistry, Biochemistry, Multiprotein Complexes, biological phenomena, cell phenomena, and immunity, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306867a76ae66c8cd43070eada3d5730
https://doi.org/10.1126/science.aab2674

المؤلفون: Abner Louissaint, Elizaveta Freinkman, Xin Gao, Naama Kanarek, Caroline A. Lewis, Monther Abu-Remaileh, David M. Sabatini, Jason R. Cantor

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Sabatini, David

المصدر: Elsevier

مصطلحات موضوعية: Male, 0301 basic medicine, Orotate Phosphoribosyltransferase, Metabolite, Orotidine-5'-Phosphate Decarboxylase, Cell Culture Techniques, Endogeny, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Multienzyme Complexes, Cell Line, Tumor, Uridine monophosphate, Metabolome, Animals, Humans, Aged, ATP synthase, Metabolism, Middle Aged, Culture Media, Uric Acid, Leukemia, Myeloid, Acute, Glucose, Pyrimidines, 030104 developmental biology, chemistry, Biochemistry, Cancer cell, biology.protein, Uric acid, Fluorouracil

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794de047b4b2d3da712c9fb0d444df92
https://orcid.org/0000-0002-1446-7256

المؤلفون: Aakanksha Dixit, Jason R. Cantor, Brent L. Iverson, Tae Hyeon Yoo, George Georgiou, Thomas G. Forsthuber

المصدر: Proceedings of the National Academy of Sciences. 108:1272-1277

مصطلحات موضوعية: Male, Models, Molecular, T-Lymphocytes, Epitopes, T-Lymphocyte, Heterologous, Mice, Transgenic, Computational biology, Biology, medicine.disease_cause, Epitope, Interferon-gamma, Mice, Peptide Library, Catalytic Domain, medicine, Animals, Asparaginase, Humans, Saturated mutagenesis, Deimmunization, Mutation, Multidisciplinary, Escherichia coli Proteins, Immunogenicity, Genetic Drift, Computational Biology, HLA-DR Antigens, Protein engineering, Biological Sciences, Flow Cytometry, Directed evolution, Molecular biology, Protein Structure, Tertiary, Female, Immunization, Directed Molecular Evolution, HLA-DRB1 Chains

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd34e319f265162cf6e565324aed16d
https://doi.org/10.1073/pnas.1014739108

المؤلفون: Lynne Chantranupong, George Georgiou, Jason R. Cantor, Everett Stone

المصدر: Biochemistry. 48:11026-11031

مصطلحات موضوعية: Models, Molecular, Dipeptidases, Methyltransferase, Molecular Sequence Data, Biology, Autoantigens, Biochemistry, Article, Amidohydrolases, Catalytic Domain, Asparaginase, Humans, ASPARAGINASE-LIKE PROTEIN 1, Amino Acid Sequence, chemistry.chemical_classification, Activity profile, Sequence Homology, Amino Acid, Dipeptides, Mammalian brain, biology.organism_classification, Molecular biology, Aspartyl Peptidase, Recombinant Proteins, Kinetics, Enzyme, Amino Acid Substitution, chemistry, Ntn hydrolase, Biocatalysis, Protein Processing, Post-Translational, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe9043f2cb634d2bc4f8f83568403c5
https://doi.org/10.1021/bi901397h

المؤلفون: George Georgiou, Brent L. Iverson, Navin Varadarajan, Jason R. Cantor

المصدر: Nature Protocols. 4:893-901

مصطلحات موضوعية: Models, Molecular, Proteases, Oligonucleotide, Escherichia coli Proteins, Cell Membrane, Active site, Drug design, Protein engineering, Computational biology, Cell sorting, Biology, Flow Cytometry, Protein Engineering, OmpT, General Biochemistry, Genetics and Molecular Biology, Enzymes, Substrate Specificity, Catalytic Domain, Escherichia coli, biology.protein, DNA microarray, Bacterial Outer Membrane Proteins, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714dd3524f1a84785d5258decec8910c
https://doi.org/10.1038/nprot.2009.60

المؤلفون: Alexander Shekhtman, Youn-Hi Woo, Jason R. Cantor, Julio A. Camarero, Richard H. Kimura

المصدر: ChemBioChem. 8:1363-1366

مصطلحات موضوعية: Thioredoxin reductase, Organic Chemistry, Cyclotides, Biology, Biochemistry, law.invention, Cyclotide, chemistry.chemical_compound, Biosynthesis, chemistry, law, Protein splicing, Recombinant DNA, Native state, Molecular Medicine, Amino Acid Sequence, Molecular Biology, Intracellular, Plant Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a991cfe4c63a0959d170261d10aab39
https://doi.org/10.1002/cbic.200700183

المؤلفون: Dohoon Kim, Jason R. Cantor, Matija Snuderl, Keith L. Ligon, David M. Sabatini, Brian P. Fiske, Manjae Kwon, Richard Possemato, Dan Y. Gui, Elizaveta Freinkman, Michael E. Pacold, Yakov Chudnovsky, Laura M. Shelton, Kıvanç Birsoy, Walter W. Chen, Matthew G. Vander Heiden, Kenjiro Kami, Shakti Ramkissoon, Seong Woo Anthony Kang

المصدر: Nature, 520, 7547, pp. 363-7
Nature, 520, 363-7
Nature

مصطلحات موضوعية: Cell Survival, Pyruvate Kinase, Glycine, PKM2, Biology, Article, Acetone, Serine, Mice, Necrosis, Oxygen Consumption, Ischemia, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Glycine Hydroxymethyltransferase, Tumor microenvironment, Multidisciplinary, Glycine cleavage system, Brain Neoplasms, Glycine Dehydrogenase (Decarboxylating), Pyruvaldehyde, Xenograft Model Antitumor Assays, Cell Hypoxia, 3. Good health, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Biochemistry, Cell culture, Serine hydroxymethyltransferase, Cancer cell, Cancer research, Female, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3acea0493e741cb6d583d545cc6781
https://hdl.handle.net/2066/152685