المؤلفون: Joey L. Methot (1822573), Hua Zhou (50017), Meredeth A. McGowan (1995799), Neville John Anthony (10522303), Matthew Christopher (9661265), Yudith Garcia (6618500), Abdelghani Achab (2177274), Kathryn Lipford (10522306), Benjamin Wesley Trotter (6618527), Michael D. Altman (1302795), Xavier Fradera (2585029), Charles A. Lesburg (1834624), Chaomin Li (1976134), Stephen Alves (10522309), Craig P. Chappell (3863689), Renu Jain (10522312), Ruban Mangado (10522315), Elaine Pinheiro (9470096), Sybill M. G. Williams (10522318), Peter Goldenblatt (4640101), Armetta Hill (6618512), Lynsey Shaffer (4640083), Dapeng Chen (528941), Vincent Tong (1570804), Robbie L. McLeod (2351071), Hyun-Hee Lee (4255930), Hongshi Yu (1730716), Sanjiv Shah (1412503), Jason D. Katz (2188990)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Physiology, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, dose, Treg cell proliferation, C 57BL reporter mice, ovalbumin-challenged Brown Norway rats, bronchoalveolar lavage inflammation., heterocycloalkyl purine inhibitors, Hydroxypyrrolidine Purine PI 3K Imm., 3 c, PI 3K pathway, mg, MSD, PI 3K inhibitors

Relation: https://figshare.com/articles/journal_contribution/Projected_Dose_Optimization_of_Amino-_and_Hydroxypyrrolidine_Purine_PI3K_Immunomodulators/14368261

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00237.s001

المؤلفون: Joey L. Methot (1822573), Hua Zhou (50017), Meredeth A. McGowan (1995799), Neville John Anthony (10522303), Matthew Christopher (9661265), Yudith Garcia (6618500), Abdelghani Achab (2177274), Kathryn Lipford (10522306), Benjamin Wesley Trotter (6618527), Michael D. Altman (1302795), Xavier Fradera (2585029), Charles A. Lesburg (1834624), Chaomin Li (1976134), Stephen Alves (10522309), Craig P. Chappell (3863689), Renu Jain (10522312), Ruban Mangado (10522315), Elaine Pinheiro (9470096), Sybill M. G. Williams (10522318), Peter Goldenblatt (4640101), Armetta Hill (6618512), Lynsey Shaffer (4640083), Dapeng Chen (528941), Vincent Tong (1570804), Robbie L. McLeod (2351071), Hyun-Hee Lee (4255930), Hongshi Yu (1730716), Sanjiv Shah (1412503), Jason D. Katz (2188990)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Physiology, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, dose, Treg cell proliferation, C 57BL reporter mice, ovalbumin-challenged Brown Norway rats, bronchoalveolar lavage inflammation., heterocycloalkyl purine inhibitors, Hydroxypyrrolidine Purine PI 3K Imm., 3 c, PI 3K pathway, mg, MSD, PI 3K inhibitors

Relation: https://figshare.com/articles/dataset/Projected_Dose_Optimization_of_Amino-_and_Hydroxypyrrolidine_Purine_PI3K_Immunomodulators/14368264

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00237.s002

المؤلفون: Katrina M. Mennie (4180024), Michael H. Reutershan (2470597), Catherine White (7960844), Bruce Adams (10879327), Bridget Becker (10879330), James Deng (10879333), Jason D. Katz (2188990), Elisabeth LaBlue (10879336), Kaila Margrey (10879339), Josep Saurí (1523239)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Sociology, Developmental Biology, Cancer, Inorganic Chemistry, Infectious Diseases, Chemical Sciences not elsewhere classified, drug-like compounds, serendipitous discovery, regioselective synthesis, heterocyclic motifs, regioselective formation, pyridines Nitrogenous heterocycles, regioselective method

Relation: https://figshare.com/articles/journal_contribution/Divergent_and_Regioselective_Synthesis_of_Pyrazolo_1_5_i_a_i_pyridines_and_Imidazo_1_5_i_a_i_pyridines/14681545

الاتاحة: https://doi.org/10.1021/acs.orglett.1c01431.s001