المؤلفون: Diana D. Shi, Joyce H. Lee, Adam C. Wang, Januka Khanal, Wenhua Gao, William G. Kaelin, Jr., Samuel K. McBrayer

المصدر: STAR Protocols, Vol 4, Iss 2, Pp 102281- (2023)

مصطلحات موضوعية: Cancer, Model Organisms, Neuroscience, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166723002484; https://doaj.org/toc/2666-1667

URL الوصول: https://doaj.org/article/28d231ea93034d8da81fffb340a70d54

المؤلفون: Januka Khanal, Daniel P. Cahill, Joseph Buehler, Diana D. Shi, Yu-Fen Lin, Misty S. Martin-Sandoval, Michael M Levitt, Keith L. Ligon, Harley I. Kornblum, Adam C. Wang, Sungwoo Lee, Dennis M. Bonal, John M. Asara, Mark A. Lehrman, Isaac S. Harris, Andreas Janzer, Cylaina E. Bird, Michael Jeffers, Ralph J. DeBerardinis, William G. Kaelin, Tammie Dang, Nathalie Y. R. Agar, Sylwia A. Stopka, Lauren C. Gattie, Stefan Gradl, Lauren G. Zacharias, Michael S. Regan, Quang-Dé Nguyen, Tak W. Mak, Sabina Signoretti, Kalil G. Abdullah, Peter Ly, Andreas Sutter, Timothy E. Richardson, Samuel K. McBrayer, Thomas P. Mathews, Milan R. Savani, Jennifer E. Endress, Min Xu, Wenhua Gao, Bofu Huang, Rebecca B. Jennings, Ryan E. Looper

مصطلحات موضوعية: Purine, IDH1, Mutant, Synthetic lethality, Biology, medicine.disease, chemistry.chemical_compound, Isocitrate dehydrogenase, chemistry, Glioma, Pyrimidine metabolism, Cancer research, medicine, Dihydroorotate dehydrogenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ef99b65b0828b3d636a1f8cfa0b31ac5
https://doi.org/10.1101/2021.11.30.470443

المؤلفون: Diana D. Shi, Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina E. Bird, Joseph Buehler, Sylwia A. Stopka, Michael S. Regan, Yu-Fen Lin, Vinesh T. Puliyappadamba, Wenhua Gao, Januka Khanal, Laura Evans, Joyce H. Lee, Lei Guo, Yi Xiao, Min Xu, Bofu Huang, Rebecca B. Jennings, Dennis M. Bonal, Misty S. Martin-Sandoval, Tammie Dang, Lauren C. Gattie, Amy B. Cameron, Sungwoo Lee, John M. Asara, Harley I. Kornblum, Tak W. Mak, Ryan E. Looper, Quang-De Nguyen, Sabina Signoretti, Stefan Gradl, Andreas Sutter, Michael Jeffers, Andreas Janzer, Mark A. Lehrman, Lauren G. Zacharias, Thomas P. Mathews, Julie-Aurore Losman, Timothy E. Richardson, Daniel P. Cahill, Ralph J. DeBerardinis, Keith L. Ligon, Lin Xu, Peter Ly, Nathalie Y.R. Agar, Kalil G. Abdullah, Isaac S. Harris, William G. Kaelin, Samuel K. McBrayer

المصدر: Cancer Cell. 40:939-956.e16

مصطلحات موضوعية: Mice, Cancer Research, Leukemia, Pyrimidines, Oncology, Brain Neoplasms, Mutation, Animals, Glioma, Enzyme Inhibitors, Triazoles, Salicylanilides, Isocitrate Dehydrogenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8efc2185c0705640ff71c554ff4fe6
https://doi.org/10.1016/j.ccell.2022.07.011

المؤلفون: Sabina Signoretti, Kalil G. Abdullah, Januka Khanal, Quang-Dé Nguyen, Daniel P. Cahill, Dennis M. Bonal, Keith L. Ligon, Diana D. Shi, William G. Kaelin, Adam C. Wang, Samuel K. McBrayer, Michael M Levitt, Wenhua Gao, Rebecca B. Jennings

المصدر: Neuro Oncol

مصطلحات موضوعية: Cancer Research, Oncology, Oncogene, Genetically Engineered Mouse, Tumor Models, Cancer research, medicine, Neurology (clinical), IDH1 R132H, Biology, medicine.disease, neoplasms, Anaplastic astrocytoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5487eeccfdf9bb1c290f7324dd38aa81
https://europepmc.org/articles/PMC7651090/

المؤلفون: Andreas Sutter, Harley I. Kornblum, Jennifer E. Endress, Isaac S. Harris, William G. Kaelin, Adam C. Wang, Daniel P. Cahill, Min Xu, Diana D. Shi, Januka Khanal, Wenhua Gao, Stefan Gradl, Dennis M. Bonal, Quang-Dé Nguyen, Keith L. Ligon, Samuel K. McBrayer, Michael Jeffers, Michael M Levitt, Andreas Janzer, Kalil G. Abdullah

المصدر: Neuro-oncology Advances

مصطلحات موضوعية: Mutation, Mutant, Astrocytoma, Metabolic Drug Targets, Resistance, Biology, medicine.disease, medicine.disease_cause, Supplement Abstracts, Isocitrate dehydrogenase, Cell culture, Glioma, Pyrimidine metabolism, Pyrimidine Synthesis Inhibition, medicine, Cancer research, AcademicSubjects/MED00300, AcademicSubjects/MED00310

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c10160a44ca8baa2c38c07d960be79
http://europepmc.org/articles/PMC7992238

المؤلفون: Samuel K, McBrayer, Benjamin A, Olenchock, Gabriel J, DiNatale, Diana D, Shi, Januka, Khanal, Rebecca B, Jennings, Jesse S, Novak, Matthew G, Oser, Alissa K, Robbins, Rebecca, Modiste, Dennis, Bonal, Javid, Moslehi, Roderick T, Bronson, Donna, Neuberg, Quang-De, Nguyen, Sabina, Signoretti, Julie-Aurore, Losman, William G, Kaelin

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(16)

مصطلحات موضوعية: Jumonji Domain-Containing Histone Demethylases, Integrases, Heart Septal Defects, Recombinant Fusion Proteins, Fibroblasts, Retinoblastoma Protein, eye diseases, Neoplasm Proteins, DNA-Binding Proteins, Enzyme Activation, Histone Code, Mice, Inbred C57BL, Mice, Tamoxifen, PNAS Plus, Echocardiography, Animals, Pituitary Neoplasms, Molecular Targeted Therapy, Thyroid Neoplasms, Transgenes, Genes, Retinoblastoma, Alleles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5c9505a7016bf0317e2ac52b97e29028
https://pubmed.ncbi.nlm.nih.gov/29610306

المؤلفون: Matthew G. Oser, Rebecca B. Jennings, Januka Khanal, Javid Moslehi, Donna Neuberg, Jesse Novak, William G. Kaelin, Julie-Aurore Losman, Dennis M. Bonal, Benjamin A. Olenchock, Roderick T. Bronson, Samuel K. McBrayer, Rebecca Modiste, Gabriel J. DiNatale, Diana D. Shi, Quang-Dé Nguyen, Sabina Signoretti, Alissa Robbins

المصدر: Proceedings of the National Academy of Sciences. 115

مصطلحات موضوعية: 0301 basic medicine, Phenocopy, Multidisciplinary, biology, Retinoblastoma protein, Pituitary neoplasm, medicine.disease_cause, eye diseases, 03 medical and health sciences, 030104 developmental biology, KDM5A, Cancer research, biology.protein, medicine, Demethylase, Histone code, Epigenetics, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1732f1fb274ba2f1b2b214a74c78c4
https://doi.org/10.1073/pnas.1716029115

المؤلفون: Ruben D. Carrasco, Jared R. Mayers, William G. Kaelin, Neela H. Yennawar, Daniel P. Cahill, John M. Asara, Diana D. Shi, Sarah J. Shareef, Kimberly J. Briggs, Alissa Robbins, Samuel K. McBrayer, Kensuke Tateishi, Christian M. Metallo, Ryan E. Looper, Januka Khanal, Jessica B. Spinelli, Matthew G. Vander Heiden, Marcia C. Haigis, Kristopher A. Sarosiek, Mirazul Islam, Keith L. Ligon, Seth J. Parker, Abhishek A. Chakraborty, Bradley E. Bernstein, Tomasz Sewastianik, Benjamin A. Olenchock, Gabriel J. DiNatale

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT

المصدر: PMC

مصطلحات موضوعية: 0301 basic medicine, Mutant, Glutamic Acid, Biology, Pregnancy Proteins, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Glutarates, Minor Histocompatibility Antigens, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Glioma, Cell Line, Tumor, medicine, Homeostasis, Humans, Transaminases, chemistry.chemical_classification, Glutaminase, Glutamate receptor, Glutathione, medicine.disease, Isocitrate Dehydrogenase, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Mutation, Oxidation-Reduction, Oxidative stress

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4117d114cfe81c571c69cd6b4f2f9c6
https://pubmed.ncbi.nlm.nih.gov/30220459

المؤلفون: V. Daniel Castracane, Robert R. Kraemer, Christopher Oglesby, Penny E. Shockett, Alina Sitaula, Januka Khanal, William A. Meachum

المصدر: Physiological Reports

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Mitochondrial DNA, Time Factors, Physiology, Plasma Cells, Inflammation, cell‐free mitochondrial DNA, Plasma cell, Biology, Systemic inflammation, DNA, Mitochondrial, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Aerobic exercise, DAMP, Humans, Young adult, Cell‐free DNA, Original Research, exercise, Damage-associated molecular pattern, VO2 max, 030229 sport sciences, damage‐associated molecular pattern, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, inflammation, Immunology, Exercise Test, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc309af0b458d297529e4cfd0335ac6c
http://europepmc.org/articles/PMC4760406

المؤلفون: Penny Shockett, Januka Khanal, Alina Sitaula, Robert Kraemer

المصدر: The Journal of Immunology. 194:52.31-52.31

مصطلحات موضوعية: Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b43448d416738799d15b51e5ae69f6a8
https://doi.org/10.4049/jimmunol.194.supp.52.31