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1Academic Journal
المؤلفون: Peter Hoogerhout, Willem Kamphuis, Humphrey F Brugghe, Jacqueline A Sluijs, Hans A M Timmermans, Janny Westdijk, Gijsbert Zomer, Claire J P Boog, Elly M Hol, Germie P J M van den Dobbelsteen
المصدر: PLoS ONE, Vol 6, Iss 4, p e19110 (2011)
وصف الملف: electronic resource
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المؤلفون: Janny Westdijk, Amy Kogelman, Robert van der Put, Zaskia Eksteen, Diego Suarez, Gideon F.A. Kersten, Bernard Metz, Maarten Danial
المصدر: Journal of Pharmaceutical Sciences, 111(4), 1058-1069
مصطلحات موضوعية: Poliovirus, Poliovirus Vaccine, Inactivated, Poliovirus Vaccine, Oral, viruses, Humans, Pharmaceutical Science, Antibodies, Viral, Antigens, Viral, complex mixtures, Poliomyelitis
وصف الملف: application/pdf
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المؤلفون: Philippe J. Sansonetti, Armelle Phalipon, Jacob Atsmon, Anya Bialik, Alexandra Dorman, Shiri Meron-Sudai, Cecile Artaud, Carla W G Hoitink, Shai Ashkenazi, Valeria Asato, Arava Reizis, Marie-Lise Gougeon, Laurence A. Mulard, Ortal Ariel-Cohen, Dani Cohen, Sophy Goren, Janny Westdijk
المساهمون: Tel Aviv University (TAU), Centre de Recherche Translationnelle - Center for Translational Science (CRT), Institut Pasteur [Paris] (IP), Immunité Innée - Innate Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Translational Vaccinology (INTRAVACC), Ariel University, Pathogénie microbienne moléculaire, Chimie des Biomolécules - Chemistry of Biomolecules, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This Article is dedicated to the late John B Robbins and to Rachel Schneerson formerly at the National Institute of Child Health and Human Development, National Institutes of Health, for their groundbreaking achievements and inspiring visionary leadership in the field of shigella glycoconjugate vaccine development. We thank the members of the Centre de Recherche Translationnelle—Coordination Clinique, Institut Pasteur: Mohand Ait Ahmed for his help in site trial implementation, Nathalie Jolly for helpful discussions about trial conduct, and Hélène Lafolly for her help at the early stages of the clinical project. We acknowledge Odile Launay (CIC Cochin Pasteur), Beatrice De Vos (Consultant), and Eli Somekh (Wolfson Medical Center) for agreeing to be members of the independent data monitoring committee.
المصدر: The Lancet Infectious Diseases
The Lancet Infectious Diseases, 2021, 21 (4), pp.546-558. ⟨10.1016/S1473-3099(20)30488-6⟩مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Population, Dose-Response Relationship, Immunologic, Placebo-controlled study, Aluminum Hydroxide, Placebo, Injections, Intramuscular, Shigella flexneri, Young Adult, 03 medical and health sciences, Immunogenicity, Vaccine, 0302 clinical medicine, Adjuvants, Immunologic, Shigella Vaccines, Conjugate vaccine, Internal medicine, Humans, Medicine, media_common.cataloged_instance, Single-Blind Method, 030212 general & internal medicine, European union, education, Adverse effect, Dysentery, Bacillary, media_common, Vaccines, Synthetic, education.field_of_study, Vaccines, Conjugate, business.industry, Immunogenicity, O Antigens, Middle Aged, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Antibodies, Bacterial, Healthy Volunteers, 030104 developmental biology, Infectious Diseases, Tolerability, Female, business
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المؤلفون: Robert M F, van der Put, Carolien, Smitsman, Alex, de Haan, Martin, Hamzink, Hans, Timmermans, Joost, Uittenbogaard, Janny, Westdijk, Michiel, Stork, Olga, Ophorst, Françoise, Thouron, Catherine, Guerreiro, Philippe J, Sansonetti, Armelle, Phalipon, Laurence A, Mulard
المصدر: ACS central science. 8(4)
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المؤلفون: Rebecca Riches-Duit, Alexandre Dobly, Laura Hassall, Bazbek Davletov, Shalini Rajagopal, Ciara Doran, Antoine Francotte, Amy Kogelman, Paul Stickings, Janny Westdijk
المصدر: Biologicals
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Diphtheria Toxoid, Bioengineering, Monoclonal antibody, Applied Microbiology and Biotechnology, Epitope, 03 medical and health sciences, 0302 clinical medicine, Antigen, medicine, Potency, 030212 general & internal medicine, Vaccine Potency, Pharmacology, Immunoassay, General Immunology and Microbiology, medicine.diagnostic_test, biology, Chemistry, Toxoid, Antibodies, Monoclonal, Diphtheria, General Medicine, Virology, 3. Good health, 030104 developmental biology, biology.protein, Antibody, Biotechnology
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المؤلفون: Nanda Spruit, Wichard Tilstra, Janny Westdijk, Bernard Metz, Coenraad F.M. Hendriksen, Gideon F.A. Kersten, Johan van der Gun
المصدر: Biologicals, 47, 69-75
مصطلحات موضوعية: 0301 basic medicine, Antigenicity, Diphtheria Toxoid, medicine.drug_class, Antigenic fingerprinting, Bioengineering, Monoclonal antibody, complex mixtures, Applied Microbiology and Biotechnology, Epitope, Phosphates, Microbiology, Antibodies, Monoclonal, Murine-Derived, 03 medical and health sciences, chemistry.chemical_compound, Immunogenicity, Vaccine, 0302 clinical medicine, Adsorption, Antigen, medicine, Aluminium phosphate, 030212 general & internal medicine, Aluminum Compounds, Pharmacology, Diphtheria toxin, Antigens, Bacterial, Chromatography, General Immunology and Microbiology, Chemistry, Toxoid, General Medicine, Antibodies, Bacterial, 030104 developmental biology, ELISA, Consistency, Biotechnology
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المؤلفون: Humphrey F. Brugghe, Wichard Tilstra, Peter Hoogerhout, Harry van Steeg, Janny Westdijk, Cornelis Kees Mulder, Ulrich L. M. Eisel, Yun Dong, Elly van Riet, Hans A. M. Timmermans
المساهمون: Eisel lab
المصدر: Journal of Alzheimer's Disease
Journal of Alzheimer’s Disease, 52(3), 1111-1123. IOS Pressمصطلحات موضوعية: 0301 basic medicine, Male, PROTEIN, amyloid-beta protein (1-42), Pharmacology, Active immunization, Nucleus basalis, chemistry.chemical_compound, 0302 clinical medicine, RAT NUCLEUS BASALIS, Choline, PEPTIDE, stereotactic injection, amyloid-β protein (1–42), MONOPHOSPHORYL-LIPID-A, HYPOTHESIS, General Neuroscience, Neurodegeneration, Neurodegenerative Diseases, General Medicine, Alzheimer's disease, ALZHEIMERS-DISEASE, Psychiatry and Mental health, Clinical Psychology, Basal Nucleus of Meynert, Stereotactic injection, NEUROFIBRILLARY TANGLES, Alzheimer’s disease, Research Article, mice, cholinergic fibers, Enzyme-Linked Immunosorbent Assay, Biology, cyclopeptides, immunization, nucleus basalis of Meynert, Peptides, Cyclic, Choline O-Acetyltransferase, 03 medical and health sciences, Immune system, In vivo, medicine, Animals, IMMUNOTHERAPY, Amyloid beta-Peptides, IN-VITRO, medicine.disease, Peptide Fragments, Mice, Inbred C57BL, PATHOLOGY, Disease Models, Animal, 030104 developmental biology, chemistry, Immunology, Cholinergic, Geriatrics and Gerontology, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Wilfried A.M. Bakker, Benjamin P. Steil, Robert E. Johnston, Mario Barro, Patricia A. Jorquera, Janny Westdijk
المصدر: Vaccine. 32:558-563
مصطلحات موضوعية: viruses, medicine.medical_treatment, Antibodies, Viral, medicine.disease_cause, behavioral disciplines and activities, Article, Virus, Immunoglobulin G, Mice, Immune system, Adjuvants, Immunologic, Antigen, medicine, Animals, Immunity, Mucosal, Mice, Inbred BALB C, General Veterinary, General Immunology and Microbiology, biology, business.industry, Poliovirus, Public Health, Environmental and Occupational Health, social sciences, Antibodies, Neutralizing, Virology, Immunoglobulin A, Rats, Poliovirus Vaccine, Inactivated, Infectious Diseases, Antibody Formation, Immunology, Inactivated Poliovirus Vaccine, biology.protein, Molecular Medicine, Female, Antibody, business, Adjuvant
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المؤلفون: Mario Barro, Thomas S. Vedvick, Benjamin P. Steil, Gideon F.A. Kersten, Nicolas Collin, Janny Westdijk, Patrick Koedam, Wilfried A.M. Bakker, Peter van der Ley
المصدر: Vaccine, 31(9), 1298-1304
Vaccine, vol. 31, no. 9, pp. 1298-1304مصطلحات موضوعية: Serotype, medicine.medical_treatment, Antibodies, Viral, medicine.disease_cause, complex mixtures, Article, Microbiology, Adjuvants, Immunologic, Antigen, Neutralization Tests, medicine, Animals, Potency, Sabin IPV, Oil-in water, PagL, AlOH3, Replicon particles, MPL, General Veterinary, General Immunology and Microbiology, biology, business.industry, Poliovirus, Public Health, Environmental and Occupational Health, medicine.disease, Antibodies, Neutralizing, Virology, Rats, Poliomyelitis, Poliovirus Vaccines, Poliovirus Vaccine, Inactivated, Infectious Diseases, Immunization, biology.protein, Molecular Medicine, Antibody, business, Adjuvant
وصف الملف: application/pdf
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المؤلفون: Laurence A. Mulard, Catherine Guerreiro, Philippe J. Sansonetti, Françoise Thouron, Peter Hoogerhout, Michiel Stork, Tae Hee Kim, Armelle Phalipon, Janny Westdijk, Robert M. F. van der Put
المساهمون: Institute for Translational Vaccinology (INTRAVACC), Chimie des Biomolécules - Chemistry of Biomolecules, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Pathogénie microbienne moléculaire, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Chaire Microbiologie et Maladies infectieuses, Collège de France (CdF (institution)), The research leading to these results has received funding from Institut Pasteur, Agence Nationale pour la Recherche (ANR (France), Grant ANR-06-EMPB-013-02, GLYCOVAX), Korea Science and Engineering Foundation (KOSEF, Postdoctoral fellowship to T.H.K.), the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (Grant No. ANR-10-LABX-62-IBEID), and the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement No. 261472-STOPENTERICS., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-06-EMPB-0013,GLYCOVAX-SF2A,Validation d'un vaccin glycoconjugué chimiquement défini(2006), European Project: 261472,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,STOPENTERICS(2010), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Collège de France - Chaire Microbiologie et Maladies infectieuses
المصدر: Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2016, 27 (4), pp.883-92. ⟨10.1021/acs.bioconjchem.5b00617⟩
Bioconjugate Chemistry, 2016, 27 (4), pp.883-92. ⟨10.1021/acs.bioconjchem.5b00617⟩مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, Biomedical Engineering, Carbohydrates, Pharmaceutical Science, Bioengineering, chemical and pharmacologic phenomena, 01 natural sciences, complex mixtures, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Shigella flexneri, Adjuvants, Immunologic, Conjugate vaccine, Dysentery, Bacillary, Pharmacology, Vaccines, Synthetic, Bioconjugation, biology, 010405 organic chemistry, Alum, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Immunogenicity, Organic Chemistry, Toxoid, Reproducibility of Results, biology.organism_classification, 3. Good health, 0104 chemical sciences, 030104 developmental biology, chemistry, Biochemistry, Chromatography, Gel, Alum Compounds, Shigella, [SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology, Hapten, Biotechnology, Conjugate
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المصدر: Methods in molecular biology (Clifton, N.J.). 1387
مصطلحات موضوعية: Poliovirus, Poliovirus Vaccine, Inactivated, Immunogenicity, Vaccine, Humans, Enzyme-Linked Immunosorbent Assay, Surface Plasmon Resonance, Antigens, Viral, Poliomyelitis
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المؤلفون: Ahd Hamidi, Janny Westdijk, Jan Hendriks, Gideon F.A. Kersten, Aart G. van ’t Oever, Eelco Sleeman, Wilfried A.M. Bakker, Peter van’t Veld, Monique G.C.T. van Oijen, Yvonne E. Thomassen, Nico van den Heuvel, Leo A. van der Pol, Fred W. van Nimwegen, Lars C. Sundermann
المصدر: Vaccine. 29:7188-7196
مصطلحات موضوعية: Economic growth, Vaccine Production, medicine.disease_cause, complex mixtures, World health, Cell Line, Technology Transfer, Poliomyelitis eradication, medicine, Animals, Humans, Technology, Pharmaceutical, Netherlands, General Veterinary, General Immunology and Microbiology, business.industry, Poliovirus, Public Health, Environmental and Occupational Health, Haplorhini, Biocontainment, medicine.disease, Inactivated polio vaccine, Biotechnology, Poliomyelitis, Poliovirus Vaccine, Inactivated, Infectious Diseases, Poliovirus Vaccine, Oral, Technology transfer, Molecular Medicine, business
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المؤلفون: Javier Martin, Aart G. van ’t Oever, Wilfried A.M. Bakker, Lonneke Levels, Janny Westdijk, Debbie Brugmans, Gideon F.A. Kersten
المصدر: Vaccine. 29:3390-3397
مصطلحات موضوعية: Antigenicity, Antigen Unit, education, Biology, Antibodies, Viral, behavioral disciplines and activities, complex mixtures, Virus, Antigen, mental disorders, Animals, Antigens, Viral, General Veterinary, General Immunology and Microbiology, Immunogenicity, Public Health, Environmental and Occupational Health, Wild type, social sciences, Reference Standards, Antibodies, Neutralizing, Virology, Rats, Poliovirus Vaccines, Poliovirus, Titer, Infectious Diseases, Immunology, biology.protein, Molecular Medicine, Antibody
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المصدر: Methods in Molecular Biology ISBN: 9781493932917
مصطلحات موضوعية: 0301 basic medicine, Antigenicity, Chromatography, Chemistry, Poliovirus, medicine.disease_cause, Virology, 03 medical and health sciences, Polio vaccine, 030104 developmental biology, 0302 clinical medicine, medicine, Potency, 030212 general & internal medicine, Surface plasmon resonance, Calibration free
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المؤلفون: Janny Westdijk, Patrick Koedam, R. ten Have, Martin R.J. Hamzink, Gideon F.A. Kersten, Bernard Metz, A. de Haan, L.M.A.R. Levels
المصدر: Biologicals : journal of the International Association of Biological Standardization. 43(6)
مصطلحات موضوعية: Serotype, Hot Temperature, Dose-Response Relationship, Immunologic, Bioengineering, Enzyme-Linked Immunosorbent Assay, Biosensing Techniques, medicine.disease_cause, Antibodies, Viral, Applied Microbiology and Biotechnology, Polio vaccine, Antigen, Chlorocebus aethiops, medicine, Potency, Bioassay, Animals, Trypsin, Vero Cells, Pharmacology, General Immunology and Microbiology, Virulence, business.industry, Poliovirus, General Medicine, medicine.disease, Virology, Antibodies, Neutralizing, Poliomyelitis, Rats, Europe, Poliovirus Vaccine, Inactivated, Practice Guidelines as Topic, Biological Assay, Capsid Proteins, business, Biotechnology, medicine.drug
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المؤلفون: Jan van den IJssel, Coen Beuvery, Wim Jiskoot, Marcel Thalen, Janny Westdijk
المصدر: Journal of Immunoassay. 18:267-284
مصطلحات موضوعية: Bordetella pertussis, Immunology, Cell, Enzyme-Linked Immunosorbent Assay, Bacterial growth, Pertussis toxin, Microbiology, Antigen, medicine, Virulence Factors, Bordetella, Adhesins, Bacterial, Pertussis Vaccine, Pharmacology, Antigens, Bacterial, Bacteriological Techniques, biology, Strain (chemistry), Reproducibility of Results, biology.organism_classification, Culture Media, Hemagglutinins, medicine.anatomical_structure, Pertactin, Bacterial outer membrane, Bacterial Outer Membrane Proteins, Protein Binding
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المؤلفون: Aart G. van ’t Oever, Gideon F.A. Kersten, Jan Hendriks, Wilfried A.M. Bakker, Leo A. van der Pol, Nico van den Heuvel, Rudy Hertroys, Yvonne E. Thomassen, Janny Westdijk, Monique G.C.T. van Oijen
المصدر: Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 ISBN: 9789400708839
مصطلحات موضوعية: Clinical trial, Polio vaccine, business.industry, Process development, Poliomyelitis eradication, Who guidelines, Technology transfer, Medicine, Operations management, business, Virology, Inactivated polio vaccine, Oral Poliovirus Vaccine
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المؤلفون: Carmen Arigita, Wim E. Hennink, Wim Jiskoot, Cor van Ingen, Janny Westdijk, Gideon F.A. Kersten, Daan J.A. Crommelin
المصدر: Vaccine. 22(5-6)
مصطلحات موضوعية: Antigenicity, Protein Denaturation, Chemical Phenomena, Drug Storage, Blotting, Western, Porins, Enzyme-Linked Immunosorbent Assay, Meningococcal Vaccines, Neisseria meningitidis, Microbiology, Mice, Drug Stability, Animals, Denaturation (biochemistry), Serum Bactericidal Test, Particle Size, Polyacrylamide gel electrophoresis, Guanidine, Mice, Inbred BALB C, General Veterinary, General Immunology and Microbiology, biology, Chemistry, Chemistry, Physical, Immunogenicity, Vesicle, Public Health, Environmental and Occupational Health, Tryptophan, biology.organism_classification, Infectious Diseases, Freeze Drying, Spectrometry, Fluorescence, Biophysics, Molecular Medicine, Neisseriaceae, Electrophoresis, Polyacrylamide Gel, Bacterial outer membrane, Bacterial Outer Membrane Proteins
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المصدر: Luykx, D M A M, Casteleijn, M G, Jiskoot, W, Westdijk, J & Jongen, P M J M 2004, ' Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material ', European Journal of Pharmaceutical Sciences, vol. 23, no. 1, pp. 65-75 . https://doi.org/10.1016/j.ejps.2004.05.007
مصطلحات موضوعية: Circular dichroism, Immunodiffusion, Protein Denaturation, animal structures, Chemical Phenomena, Spectrophotometry, Infrared, Protein Conformation, viruses, Fluorescence spectrometry, Pharmaceutical Science, Hemagglutinin Glycoproteins, Influenza Virus, Biology, complex mixtures, Fluorescence spectroscopy, Protein structure, SDG 3 - Good Health and Well-being, Drug Stability, Freezing, Humans, Denaturation (biochemistry), Protein secondary structure, Influenza virus haemagglutinin, Chemistry, Physical, Circular Dichroism, Circular dichroism spectroscopy, Temperature, food and beverages, virus diseases, Hemagglutinin, Hydrogen-Ion Concentration, Protein tertiary structure, Crystallography, Spectrometry, Fluorescence, Influenza Vaccines, Physicochemical characterisation, Indicators and Reagents, Spectrophotometry, Ultraviolet, Stability