المؤلفون: Andres Chana-Munoz, Agnieszka Jendroszek, Malene Sønnichsen, Rune Kristiansen, Jan K Jensen, Peter A Andreasen, Christian Bendixen, Frank Panitz

المصدر: PLoS ONE, Vol 12, Iss 8, p e0182756 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5568229?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/c85ef3a191df4876bf5dfcf9a000ee68

المؤلفون: Daniel M Dupont, Cathrine K Thuesen, Kenneth A Bøtkjær, Manja A Behrens, Karen Dam, Hans P Sørensen, Jan S Pedersen, Michael Ploug, Jan K Jensen, Peter A Andreasen

المصدر: PLoS ONE, Vol 10, Iss 3, p e0119207 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4368798?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/71ab1028c4194de6a6c9ef9ae068d7e8

المؤلفون: Baoyu Zhao, Peng Xu, Longguang Jiang, Berit Paaske, Tobias Kromann-Hansen, Jan K Jensen, Hans Peter Sørensen, Zhuo Liu, Jakob T Nielsen, Anni Christensen, Masood Hosseini, Kasper K Sørensen, Niels Christian Nielsen, Knud J Jensen, Mingdong Huang, Peter A Andreasen

المصدر: PLoS ONE, Vol 9, Iss 12, p e115872 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4278837?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/902afd0657ad41e78840e6e39a76be6b

المؤلفون: Sine Godiksen, Christoffer Soendergaard, Stine Friis, Jan K Jensen, Jette Bornholdt, Katiuchia Uzzun Sales, Mingdong Huang, Thomas H Bugge, Lotte K Vogel

المصدر: PLoS ONE, Vol 8, Iss 10, p e77146 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3799725?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6a99365eb769456299d77c1bb823a3ae

المؤلفون: Andrés Chana-Muñoz, Agnieszka Jendroszek, Malene Sønnichsen, Tobias Wang, Michael Ploug, Jan K. Jensen, Peter A. Andreasen, Christian Bendixen, Frank Panitz

المصدر: BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-17 (2019)

مصطلحات موضوعية: Plasminogen, Plasminogen activation system, Evolution, Phylogenetic analysis, Chordates, Transcriptome analysis, QH359-425

Relation: http://link.springer.com/article/10.1186/s12862-019-1353-z; https://doaj.org/toc/1471-2148; https://doaj.org/article/f88326412f624cdaaf8c846c9f0c414b

الاتاحة: https://doi.org/10.1186/s12862-019-1353-z
https://doaj.org/article/f88326412f624cdaaf8c846c9f0c414b

المؤلفون: Rasmus K. Jensen, Rasmus Pihl, Trine A.F. Gadeberg, Jan K. Jensen, Kasper R. Andersen, Steffen Thiel, Nick S. Laursen, Gregers R. Andersen

المصدر: J Biol Chem
Jensen, R K, Pihl, R, Gadeberg, T A F, Jensen, J K, Andersen, K R, Thiel, S, Laursen, N S & Andersen, G R 2023, ' Correction : A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement ', The Journal of Biological Chemistry, vol. 299, no. 2, pp. 102951 . https://doi.org/10.1016/j.jbc.2023.102951

مصطلحات موضوعية: Additions and Corrections, Cell Biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e88aca1141047dd680b2adc6433e58e
https://europepmc.org/articles/PMC9932098/

المؤلفون: Tobias Kromann-Hansen, Eva Louise Lange, Hans Peter Sørensen, Gholamreza Hassanzadeh-Ghassabeh, Mingdong Huang, Jan K. Jensen, Serge Muyldermans, Paul J. Declerck, Elizabeth A. Komives, Peter A. Andreasen

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-017-03457-7; https://doaj.org/toc/2045-2322; https://doaj.org/article/409897e4334a4c2c81d516f9a73f9d64

الاتاحة: https://doi.org/10.1038/s41598-017-03457-7
https://doaj.org/article/409897e4334a4c2c81d516f9a73f9d64

المؤلفون: Lars Vitved, Evelina Stankevic, Jan K. Jensen, Annika W. Nonboe, Lotte K. Vogel, Ásdís K. Frost, Kristian W Goderum, Lasse Holt-Danborg, Signe Skovbjerg

المصدر: Holt-Danborg, L, Skovbjerg, S, Goderum, K W, Nonboe, A W, Stankevic, E, Frost, Á K, Vitved, L, Jensen, J K & Vogel, L K 2020, ' Insights into the regulation of the matriptase-prostasin proteolytic system ', The Biochemical journal, vol. 477, no. 22, pp. 4349-4365 . https://doi.org/10.1042/BCJ20200630

مصطلحات موضوعية: Proteases, endocrine system, serine proteases, animal structures, medicine.medical_treatment, Proteinase Inhibitory Proteins, Secretory, matriptase, Cleavage (embryo), medicine.disease_cause, Biochemistry, digestive system, Serine, Dual action, Zymogen, medicine, Humans, Matriptase, Molecular Biology, Enzyme Precursors, Membrane Glycoproteins, Protease, biology, zymogen activity, Chemistry, Serine Endopeptidases, virus diseases, HAI-1, Cell Biology, Cell biology, HAI-2, enzymes and coenzymes (carbohydrates), HEK293 Cells, Proteolysis, biology.protein, prostasin, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b8c827f7b28e660d41783f2da281d
https://pure.au.dk/portal/da/publications/insights-into-the-regulation-of-the-matriptaseprostasin-proteolytic-system(9ba711c0-6c63-42ce-ab5f-ef35d419d815).html

المؤلفون: Lotte K. Vogel, Annika W. Nonboe, Cecilia C. Thomas, Lars Vitved, Ásdís K. Frost, Lasse Holt-Danborg, Signe Skovbjerg, Jan K. Jensen, Zebin Hong, Christine R. Schar

المصدر: Skovbjerg, S, Holt-Danborg, L, Nonboe, A W, Hong, Z, Frost, Á K, Schar, C R, Thomas, C C, Vitved, L, Jensen, J K & Vogel, L K 2020, ' Inhibition of an active zymogen protease : the zymogen form of matriptase is regulated by HAI-1 and HAI-2 ', The Biochemical journal, vol. 477, no. 9, pp. 1779-1794 . https://doi.org/10.1042/BCJ20200182

مصطلحات موضوعية: Proteases, animal structures, medicine.medical_treatment, serine protease, Proteinase Inhibitory Proteins, Secretory, Hepatocyte Growth Factor Activator, matriptase, Biochemistry, Serine, Zymogen, medicine, Humans, Matriptase, Molecular Biology, Secretory pathway, Serine protease, Membrane Glycoproteins, Secretory Pathway, Protease, biology, zymogen activity, Chemistry, Cell Membrane, Serine Endopeptidases, virus diseases, HAI-1, Cell Biology, Cell biology, HAI-2, HEK293 Cells, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b62bac235b7508cd90b4bebc7689f5c
https://pure.au.dk/portal/da/publications/inhibition-of-an-active-zymogen-protease(c1e131da-975e-4df8-a670-6db09d2af227).html

المؤلفون: Peng Xu, Emil Oldenburg, Peter A. Andreasen, Jan K. Jensen, Longguang Jiang, Tobias Kromann-Hansen, Mingdong Huang

المصدر: Jiang, L, Oldenburg, E, Kromann-Hansen, T, Xu, P, Jensen, J K, Andreasen, P A & Huang, M 2018, ' Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition ', Biochimica et Biophysica Acta-General Subjects, vol. 1862, no. 9, pp. 2017-2023 . https://doi.org/10.1016/j.bbagen.2018.06.016

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Conformational change, Proteases, Protein Conformation, Stereochemistry, medicine.medical_treatment, Biophysics, Peptide, Crystallography, X-Ray, Cleavage (embryo), Peptides, Cyclic, Biochemistry, Substrate Specificity, 03 medical and health sciences, Catalytic Domain, medicine, Humans, Protease Inhibitors, Molecular Biology, chemistry.chemical_classification, Serine protease, Binding Sites, Protease, biology, Crystal structure, Enzyme catalysis, Urokinase-Type Plasminogen Activator, Cyclic peptide, 030104 developmental biology, Protease inhibitor, chemistry, biology.protein, Oxyanion hole, Crystallization, Substrate, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2116c4f0345700329fa5529d63b12037
https://doi.org/10.1016/j.bbagen.2018.06.016

المؤلفون: Jens Preben Morth, Ann-Marie Lawrence-Dörner, Bernd Thiede, Steffi Munack, Ian G. Mills, Hüseyin Besir, Matthias Wilmanns, Jan K. Jensen, Lisa Gerner, Koen Temmerman

المصدر: Data in Brief, Vol 8, Iss, Pp 733-740 (2016)
Data in Brief
Gerner, L, Munack, S, Temmerman, K, Lawrence-Dörner, A M, Besir, H, Wilmanns, M, Jensen, J K, Thiede, B, Mills, I G & Morth, J P 2016, ' Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli ', Data in Brief, vol. 8, pp. 733-740 . https://doi.org/10.1016/j.dib.2016.06.033
Gerner, L, Munack, S, Temmerman, K, Lawrence-Dörner, A-M, Besir, H, Wilmanns, M, Jensen, J K, Thiede, B, Mills, I G & Morth, J P 2016, ' Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli ', Data in brief, vol. 8, pp. 733-40 . https://doi.org/10.1016/j.dib.2016.06.033

مصطلحات موضوعية: 0301 basic medicine, SEC, size-exclusion chromatography, Calmodulin, Mutant, aa, amino acid, lac operon, Biology, AMPK, adenosine monophosphate-regulated kinase, CaMKK2, medicine.disease_cause, lcsh:Computer applications to medicine. Medical informatics, law.invention, TEV, tobacco etch virus, 03 medical and health sciences, chemistry.chemical_compound, law, LDS-PAGE, lithium dodecyl sulphate–polyacrylamide gel electrophoresis, medicine, LB, Luria broth, lcsh:Science (General), Escherichia coli, CAMKK2, Data Article, CaM, calmodulin, Multidisciplinary, Kinase, CaMKK2, calcium/calmodulin-dependent kinase kinase 2, E. coli, Escherichia coli, CaMKK2:CaM, CaMKK2-CaM complex, IPTG, β-D-1-thiogalactopyranoside, LIC, ligation-independent cloning, Molecular biology, CaMK, calcium/calmodulin-dependent kinase, OD, optical density, 030104 developmental biology, chemistry, Biochemistry, PMSF, phenylmethylsulfonyl fluoride, Fermentation, Recombinant DNA, biology.protein, lcsh:R858-859.7, PMSF, lcsh:Q1-390

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dcbe4776e9f0d59086e2d513eee037
http://www.sciencedirect.com/science/article/pii/S2352340916304012

المؤلفون: Laura De Meulemeester, Zebin Hong, Peter A. Andreasen, Jan K. Jensen, Annemarie Jacobi, Jan Skov Pedersen, J. Preben Morth

المصدر: Journal of Biological Chemistry. 291:14340-14355

مصطلحات موضوعية: 0301 basic medicine, Proteases, animal structures, Cell Biology, Plasma protein binding, Hepatocyte Growth Factor Activator, Biology, Biochemistry, Transmembrane protein, Protein tertiary structure, Protein–protein interaction, Cell biology, Serine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Protein structure, 030220 oncology & carcinogenesis, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ae70fd4bf5eb00c958181b1aeca392f
https://doi.org/10.1074/jbc.m115.707240

المؤلفون: Jesper S. Johansen, Lisbeth M. Andersen, Jan K. Jensen, Daniel M. Dupont, Peter A. Andreasen, Thomas J. D. Jørgensen, Morten Beck Trelle, Jeppe B. Madsen

المصدر: Madsen, J B, Andersen, L M, Dupont, D M, Trelle, M B, Johansen, J S, Jensen, J K, Jørgensen, T J D & Andreasen, P A 2016, ' An RNA Aptamer Inhibits a Mutation-Induced Inactivating Misfolding of a Serpin ', Cell Chemical Biology, vol. 23, no. 6, pp. 700–708 . https://doi.org/10.1016/j.chembiol.2016.04.013
Madsen, J B, Andersen, L M, Dupont, D M, Trelle, M B, Johansen, J S, Jensen, J K, Jørgensen, T J D & Andreasen, P A 2016, ' An RNA Aptamer Inhibits a Mutation-Induced Inactivating Misfolding of a Serpin ', Cell Chemical Biology, vol. 23, no. 6, pp. 700-708 . https://doi.org/10.1016/j.chembiol.2016.04.013

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Folding, Proteases, animal structures, Aptamer, medicine.medical_treatment, Clinical Biochemistry, Biology, Serpin, medicine.disease_cause, Biochemistry, Mass Spectrometry, Serine, 03 medical and health sciences, Drug Discovery, Journal Article, medicine, Humans, Molecular Biology, Serpins, Pharmacology, Mutation, Protease, 030102 biochemistry & molecular biology, Deuterium Exchange Measurement, RNA, Aptamers, Nucleotide, Surface Plasmon Resonance, 030104 developmental biology, embryonic structures, Molecular Medicine, Protein folding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5b1e44e7bae7e6d201257583c136fd
https://doi.org/10.1016/j.chembiol.2016.04.013

المؤلفون: Anni Christensen, Jeppe B. Madsen, Andrés Chana-Muñoz, Simon C. Lovell, Frank Panitz, Ernst-Martin Füchtbauer, Jan K. Jensen, Agnieszka Jendroszek, Daniel M. Dupont

المصدر: Jendroszek, A, Madsen, J B, Chana-Muñoz, A, Dupont, D M, Christensen, A, Panitz, F, Füchtbauer, E-M, Lovell, S C & Jensen, J K 2019, ' Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors ', The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA118.005419
Jendroszek, A, Madsen, J B, Chana-Muñoz, A, Dupont, D M, Christensen, A, Panitz, F, Füchtbauer, E-M, Lovell, S C & Jensen, J K 2019, ' Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors ', The Journal of Biological Chemistry, vol. 294, no. 10, pp. 3794-3805 . https://doi.org/10.1074/jbc.RA118.005419

مصطلحات موضوعية: Models, Molecular, Plasminogen Activator Inhibitor 1/metabolism, 0301 basic medicine, Protein Conformation, medicine.medical_treatment, Plasma protein binding, Serpin, Plasminogen Activators/antagonists & inhibitors, Biochemistry, Evolution, Molecular, Plasminogen Activators, Urokinase-Type Plasminogen Activator/metabolism, 03 medical and health sciences, Protein structure, Plasminogen Activator Inhibitor 1, medicine, Animals, Humans, Amino Acid Sequence, Molecular Biology, Peptide sequence, Urokinase, Serine protease, Protease, 030102 biochemistry & molecular biology, biology, Chemistry, Cell Biology, Urokinase-Type Plasminogen Activator, Cell biology, 030104 developmental biology, Enzymology, biology.protein, Plasminogen activator, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb67139be6c77514b369259ac730ad4f
https://doi.org/10.1074/jbc.RA118.005419

المؤلفون: Christine R. Schar, Jan K. Jensen, Trine Tamberg, Daniel M. Dupont, Lotte K. Vogel, Zebin Hong, Signe Skovbjerg, Karsten Skjoedt, Daphné De Schepper, Lars Vitved

المصدر: Tamberg, T, Hong, Z, De Schepper, D, Skovbjerg, S, Dupont, D M, Vitved, L, Schar, C R, Skjoedt, K, Vogel, L K & Jensen, J K 2019, ' Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors ', Journal of Biological Chemistry, vol. 294, no. 1, pp. 314-326 . https://doi.org/10.1074/jbc.RA118.004126

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, serine protease, HEPATOCYTE GROWTH-FACTOR, matriptase, Crystallography, X-Ray, Biochemistry, multi-domain protein, Serine, enzyme kinetics, CRYSTAL-STRUCTURE, chemistry.chemical_classification, Enzyme Precursors, biology, Serine Endopeptidases, Protease Inhibitors/chemistry, Antibodies, Monoclonal, Transmembrane protein, Cell biology, Enzyme Precursors/antagonists & inhibitors, SURVIVAL, cancer therapy, PROTEASE MATRIPTASE, EPITHELIAL DEVELOPMENT, surface plasmon resonance (SPR), Proteases, enzyme inhibitor, Antibodies, Monoclonal/chemistry, digestive system, 03 medical and health sciences, Protein Domains, Zymogen, medicine, Humans, Matriptase, Protease Inhibitors, PLASMINOGEN-ACTIVATOR, Molecular Biology, zymogen, TTSP, Serine protease, Serine Endopeptidases/chemistry, Protease, COMPLEX, 030102 biochemistry & molecular biology, CLEAVAGE, POTENT, Cell Biology, epitope mapping, 030104 developmental biology, Enzyme, HEK293 Cells, chemistry, Proteolysis, biology.protein, Enzymology, FACTOR ACTIVATOR INHIBITOR-1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995587780c383509d5d276e1e041795d
https://pubmed.ncbi.nlm.nih.gov/30409910

المؤلفون: Ian G. Mills, Steffi Munack, Hüseyin Besir, Bernd Thiede, Ann-Marie Lawrence-Dörner, Matthias Wilmanns, Jan K. Jensen, Jens Preben Morth, Lisa Gerner, Koen Temmerman

المصدر: Gerner, L, Munack, S, Temmerman, K, Lawrence-Dörner, A M, Besir, H, Wilmanns, M, Jensen, J K, Thiede, B, Mills, I G & Morth, J P 2016, ' Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2 ', Biochemical and Biophysical Research Communications, vol. 476, no. 2, pp. 102-107 . https://doi.org/10.1016/j.bbrc.2016.05.045
Gerner, L, Munack, S, Temmerman, K, Lawrence-Dörner, A-M, Besir, H, Wilmans, M, Jensen, J K, Thiede, B, Mills, I G & Morth, J P 2016, ' Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2 ', Biochemical and Biophysical Research Communications, vol. 476, no. 2, pp. 102-107 . https://doi.org/10.1016/j.bbrc.2016.05.045

مصطلحات موضوعية: 0301 basic medicine, Calmodulin, Drug Evaluation, Preclinical, Biophysics, Calcium-Calmodulin-Dependent Protein Kinase Kinase, Plasma protein binding, Biology, CaMKK2, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Fluorescent probe, Adenosine Triphosphate, SDG 3 - Good Health and Well-being, Humans, Amino Acid Sequence, Binding site, Phosphorylation, Protein Kinase Inhibitors, Molecular Biology, Fluorescent Dyes, CAMKK2, Binding Sites, 030102 biochemistry & molecular biology, Kinase, Cell Biology, STO-609, Recombinant Proteins, Kinome, Naphthalimides, Spectrometry, Fluorescence, 030104 developmental biology, Protein kinase domain, chemistry, Drug screening, biology.protein, Benzimidazoles, Adenosine triphosphate, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f437c64c7c1e7d14d7a8f79867d974
https://ora.ox.ac.uk/objects/uuid:6d314936-2e81-4dc5-b23f-555efe0b0092

المؤلفون: Steffen Thiel, Trine A.F. Gadeberg, Jan K. Jensen, Rasmus Pihl, Gregers R. Andersen, Rasmus K. Jensen, Kasper R. Andersen, Nick S. Laursen

المصدر: Jensen, R K, Pihl, R, Gadeberg, T A F, Jensen, J K, Andersen, K R, Thiel, S, Laursen, N S & Andersen, G R 2018, ' A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement ', Journal of Biological Chemistry, vol. 293, no. 17, pp. 6269-6281 . https://doi.org/10.1074/jbc.RA117.001179
The journal of biological chemistry 293(17), 6269-6281 (2018). doi:10.1074/jbc.RA117.001179

مصطلحات موضوعية: 0301 basic medicine, Glycan, Complement Pathway, Alternative, Complement factor I, Antigen-Antibody Complex, Crystallography, X-Ray, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Animals, Humans, Protein Structure, Quaternary, Molecular Biology, Innate immune system, biology, Chemistry, Cell Biology, Complement C3, Single-Domain Antibodies, Complement (complexity), Complement system, Cell biology, 030104 developmental biology, Structural biology, ddc:540, Protein Structure and Folding, Alternative complement pathway, biology.protein, Camelids, New World, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ff9f9be8df5b9b070788d76b6c6276

المؤلفون: Tobias Wang, Andrés C Muñoz, Malene Sønnichsen, Steen V. Petersen, Frank Panitz, Jan K. Jensen, Agnieszka Jendroszek, Christian Bendixen, Anni Christensen, Peter A. Andreasen, Kato Leyman

المصدر: Jendroszek, A, Sønnichsen, M, Chana Munoz, A, Leyman, K, Christensen, A, Petersen, S V, Bendixen, C, Panitz, F, Andreasen, P & Jensen, J K 2017, ' Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved. ', Thrombosis and Haemostasis, vol. 117, no. 9, pp. 1688-1699 . https://doi.org/10.1160/TH17-02-0102

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Folding, Glycosylation, medicine.medical_treatment, Proteolysis, Regulator, 030204 cardiovascular system & hematology, Biology, Conserved sequence, Evolution, Molecular, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Species Specificity, Plasminogen Activator Inhibitor 1, medicine, Animals, Amino Acid Sequence, Peptide sequence, Conserved Sequence, Phylogeny, Protopterus, Protease, medicine.diagnostic_test, Protein Stability, Hematology, biology.organism_classification, Recombinant Proteins, Squalus acanthias, Kinetics, 030104 developmental biology, chemistry, Biochemistry, Plasminogen activator inhibitor-1, Solvents, Protein folding, Protein Conformation, beta-Strand, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6148d9b66a06b9ee389553ef794f3f
https://pure.au.dk/portal/da/publications/latency-transition-of-plasminogen-activator-inhibitor-type-1-is-evolutionarily-conserved(d3dfa7e8-066c-41f8-a643-63c59db00af7).html

المؤلفون: James A. Huntington, Jan K. Jensen, Morten Kjeldgaard, Manja A. Behrens, Jan Skov Pedersen, Timothy J. Sendall

المصدر: Behrens, M A, Sendall, T J, Pedersen, J S, Kjeldgaard, M, Huntington, J A & Jensen, J K 2014, ' The Shapes of Z-α1-Antitrypsin Polymers in Solution Support the C-Terminal Domain-Swap Mechanism of Polymerization ', Biophysical Journal, vol. 107, no. 8, pp. 1905-1912 . https://doi.org/10.1016/j.bpj.2014.08.030

مصطلحات موضوعية: Stereochemistry, Pentamer, Molecular Sequence Data, Biophysics, Trimer, Molecular Dynamics Simulation, Protein structure, X-Ray Diffraction, Tetramer, Scattering, Small Angle, Humans, Amino Acid Sequence, Serine protease, chemistry.chemical_classification, biology, Chemistry, Small-angle X-ray scattering, fungi, Polymer, Protein Structure, Tertiary, Crystallography, Polymerization, alpha 1-Antitrypsin, Mutation, biology.protein, Protein Multimerization, Proteins and Nucleic Acids, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c7ba7c37caa5c56eb4d23281576676
https://doi.org/10.1016/j.bpj.2014.08.030

المؤلفون: Frans A. A. Mulder, Berit Paaske, Anni Christensen, Longguang Jiang, Niels Christian Nielsen, Peter A. Andreasen, Mingdong Huang, Knud J. Jensen, Jakob Nielsen, Renée Roodbeen, Jan K. Jensen

المصدر: ChemBioChem. 14:2179-2188

مصطلحات موضوعية: Stereochemistry, medicine.medical_treatment, Peptide, Crystallography, X-Ray, Peptides, Cyclic, Biochemistry, Protein Structure, Secondary, medicine, Humans, Peptide bond, Protease Inhibitors, Amino Acid Sequence, Molecular Biology, Serine protease, chemistry.chemical_classification, Binding Sites, Protease, Bicyclic molecule, biology, Organic Chemistry, Rational design, Isothermal titration calorimetry, Urokinase-Type Plasminogen Activator, Protein Structure, Tertiary, Kinetics, chemistry, Drug Design, biology.protein, Molecular Medicine, Plasminogen activator, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f736241fd38bdaa284a6bbfa67ac70
https://doi.org/10.1002/cbic.201300335