المؤلفون: Parisa Karimi Tari, Charles J. Cohen, Matthew Waldbrook, Christoph Martin Dehnhardt, Clint Young, Maegan Soriano, Rainbow Kwan, Matt Taron, Kristen Burford, Sultan Chowdhury, Noah G. Shuart, Lofstrand Verner Alexander, Michael D. Wilson, Karen Nelkenbrecher, Jean-Christophe Andrez, Michael Edward Grimwood, Wei Gong, Robert J. DeVita, J. P. Johnson, James Roy Empfield, Alla Yurevna Zenova, Luis Sojo, Andrea Lindgren, Thilo Focken, Shannon Decker, Gina de Boer, Samuel J. Goodchild, Wesolowski Steven Sigmund, Sophia Lin, Stephanie Lee

المصدر: Journal of Medicinal Chemistry. 62:9618-9641

مصطلحات موضوعية: Drug, 0303 health sciences, media_common.quotation_subject, Sodium channel, medicine.medical_treatment, Pregnane, Pharmacology, medicine.disease, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Epilepsy, chemistry.chemical_compound, Anticonvulsant, chemistry, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, Efflux, Penetrant (biochemical), 030304 developmental biology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::25eea9fc94c4d0a50d32b1585395b3e1
https://doi.org/10.1021/acs.jmedchem.9b01032

المؤلفون: Sultan Chowdhury, David Bogucki, Rostam Namdari, Girish Bankar, Wei Zhang, James Roy Empfield, Matthew Waldbrook, Stephanie M Lee, Lofstrand Verner Alexander, Karen Nelkenbrecher, Samuel J. Goodchild, Rhena Yoo, Noah G. Shuart, Wesolowski Steven Sigmund, Elaine Chang, Mandy Feng, Clint Young, Christoph Martin Dehnhardt, Jenny Li, Zhiwei Xie, Michael Edward Grimwood, Abid Hasan, Sophia Lin, Kristen Burford, Raymond J. Winquist, Charles J. Cohen, Alla Yurevna Zenova, Simon N. Pimstone, Michael R. Wilson, Parisa Karimi Tari, Kuldip Khakh, Celine Dube, Aaron M. Williams, Robin Sherrington, Luis Sojo, Andrea Lindgren, J. P. Johnson, Thilo Focken, Qi Jia, Jean-Christophe Andrez, Shannon Decker, Matthew Taron, Diana Weeratunge, Richard T. Dean, Janette Mezeyova, Shaoyi Sun, Wei Gong, Angela Hussainkhel, Gina de Boer, Alison Jane Cutts

مصطلحات موضوعية: Phenytoin, Glutamatergic, Lacosamide, Chemistry, Sodium channel, Excitatory postsynaptic potential, medicine, Carbamazepine, Pharmacology, Inhibitory postsynaptic potential, IC50, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32e2e6674136369f3abcd5070b52e762
https://doi.org/10.1101/2021.08.29.458125

المؤلفون: T. Grant, C.A. Frank, Daniel Ray Mayhugh, James Roy Empfield, C.J. Ohnmacht, Jack H. Li

المصدر: Bioorganic & Medicinal Chemistry Letters. 7:775-778

مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Haloalcohol, Biochemistry, Chemical synthesis, Potassium channel, Sulfonamide, chemistry, Drug Discovery, medicine, Molecular Medicine, Organic chemistry, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::45f91d22cf080ab0cf19d69300d93dc4
https://doi.org/10.1016/s0960-894x(97)00111-x

المؤلفون: C.J. Ohnmacht, Howard S. Shapiro, Frederick J. Brown, C.A. Frank, Christopher Ceccarelli, R. W. Smith, Keith Hopkinson Gibson, Kathleen L. Neilson, Keith Russell, Paul James Warwick, Janet M. Forst, James Hulsizer, Joseph James Lewis, Martin Dyroff, Tracy J. Halterman, Diane Amy Trainor, Jack H. Li, James Roy Empfield, Christopher L. Yochim, M. Kirkland, Sen T. Kau, T. Grant, Margaret M. Lin, Robert Joseph Harris, Burton B. Howe, Alexa L. Chun, S. Trivedi, Mclaren Frances Marie, Stuart M. Silverman, Brian Bernard Masek, Daniel Ray Mayhugh

المصدر: Journal of Medicinal Chemistry. 39:4592-4601

مصطلحات موضوعية: Potassium Channels, ATP-sensitive potassium channel, Stereochemistry, medicine.drug_class, Urinary Bladder, Carboxamide, In Vitro Techniques, Chemical synthesis, Sulfone, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cricetinae, Drug Discovery, medicine, Animals, Sulfonyl, chemistry.chemical_classification, Aryl, Muscle, Smooth, Amides, Potassium channel, Rats, Urinary Incontinence, chemistry, Molecular Medicine, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da246722b658b8996532067701cea520
https://doi.org/10.1021/jm960365n

المؤلفون: C.J. Ohnmacht, T. Grant, Daniel Ray Mayhugh, James Roy Empfield, C.A. Frank, Jack H. Li

المصدر: ChemInform. 28

مصطلحات موضوعية: Series (mathematics), Chemistry, General Medicine, Combinatorial chemistry, Chemical synthesis, Potassium channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::594b858582b9b7bdbcfa3acf440b98f9
https://doi.org/10.1002/chin.199734099

المؤلفون: L. Potter-Lee, Keith Russell, G.D. Yasay, Diane Amy Trainor, Li Jia-He, Sen T. Kau, S. Trivedi, James Roy Empfield, C.J. Ohnmacht

المصدر: Biochemical and biophysical research communications. 213(2)

مصطلحات موضوعية: medicine.medical_specialty, Potassium Channels, Charybdotoxin, Muscle Relaxation, Guinea Pigs, Urinary Bladder, Biophysics, Scorpion Venoms, Biochemistry, Potassium Chloride, Guinea pig, chemistry.chemical_compound, Internal medicine, medicine, Animals, Humans, Molecular Biology, Calcimycin, K channels, Urinary bladder, Electric Conductivity, Conductance, Muscle, Smooth, Cell Biology, Anatomy, Calcium dependent, medicine.anatomical_structure, Endocrinology, chemistry, Relaxation effect, Benzimidazoles, Calcium, Efflux, Peptides, Rubidium Radioisotopes, Chlorophenols

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7317696fb6040239dd67221fe51fae8f
https://pubmed.ncbi.nlm.nih.gov/7544120

المؤلفون: James Roy Empfield, Keith Russell

المصدر: Annual Reports in Medicinal Chemistry ISBN: 9780120405305

مصطلحات موضوعية: SK channel, chemistry.chemical_compound, BK channel, chemistry, biology, Inward-rectifier potassium ion channel, biology.protein, Cardiac action potential, Voltage-gated potassium channel, Pharmacology, Cromakalim, Calcium-activated potassium channel, Potassium channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a457235dae6277087d101b05cad7841f
https://doi.org/10.1016/s0065-7743(08)60922-7