المؤلفون: Shitalben Patel, Marie Karlsson, Joseph T. Klahn, Frank Gambino, Jr., Helena Costa, Kathleen A. McGuire, Christina K. Baumgartner, Jon Williams, Sarah Sandoz, James E. Kath

المصدر: SLAS Discovery, Vol 29, Iss 2, Pp 100135- (2024)

مصطلحات موضوعية: CETSA, Target engagement, Blood, RIPK1, Medicine (General), R5-920, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472555223000977; https://doaj.org/toc/2472-5552

URL الوصول: https://doaj.org/article/80857a2b20534901930e128e510dcb8b

المؤلفون: Elizabeth S. Thrall, James E. Kath, Seungwoo Chang, Joseph J. Loparo

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d3bdcb38b59846ff94dc46e555e13faf

المؤلفون: Michelle K Scotland, Justin M H Heltzel, James E Kath, Jung-Suk Choi, Anthony J Berdis, Joseph J Loparo, Mark D Sutton

المصدر: PLoS Genetics, Vol 11, Iss 9, p e1005507 (2015)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4564189?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/a93f1e5911504317a3253dcdaa0248cf

المؤلفون: Michael C. Jewett, William D. Wiseman, Rajesh R. Naik, Jasmine M. Hershewe, Chelsea C. Buck, Maneesh K. Gupta, James E. Kath, Patrick B. Dennis

المصدر: ACS synthetic biology. 9(12)

مصطلحات موضوعية: Protein Folding, Fluorophore, Phenylalanine, Biomedical Engineering, Supramolecular chemistry, Nanotechnology, Conjugated system, Biochemistry, Genetics and Molecular Biology (miscellaneous), chemistry.chemical_compound, Escherichia coli, Animals, Point Mutation, Protein secondary structure, chemistry.chemical_classification, Cycloaddition Reaction, Decapodiformes, Proteins, General Medicine, Hydrogen-Ion Concentration, Recombinant Proteins, Characterization (materials science), Amino acid, chemistry, Solubility, PEGylation, Protein Conformation, beta-Strand, Salts, Self-assembly

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519244aeb4c58500101f9fadcc8f797f
https://pubmed.ncbi.nlm.nih.gov/33201684

المؤلفون: Aleksandra Baranczak, James E. Kath

المصدر: Chemical communications (Cambridge, England). 55(63)

مصطلحات موضوعية: Computer science, Chemical biology, Computational biology, 010402 general chemistry, 01 natural sciences, Catalysis, Materials Chemistry, Animals, Drug Interactions, Enzyme Inhibitors, Protein Kinase Inhibitors, 010405 organic chemistry, Drug candidate, Metals and Alloys, Target engagement, Late stage, General Chemistry, Small molecule, Therapeutic modalities, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Pharmaceutical Preparations, Biological target, Direct binding, Models, Animal, Ceramics and Composites

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae0cec3a703a7c7b09b712f5ebf5087
https://pubmed.ncbi.nlm.nih.gov/31328738

المؤلفون: Joseph J. Loparo, Slobodan Jergic, Elizabeth S. Thrall, Seungwoo Chang, Karel Naiman, Nicholas E. Dixon, James E. Kath, Robert P. P. Fuchs

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: DNA Replication, DNA, Bacterial, Exonuclease, DNA Repair, Protein subunit, DNA-Directed DNA Polymerase, Lesion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Escherichia coli, medicine, Polymerase, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, DNA synthesis, Escherichia coli Proteins, DNA replication, Biological Sciences, Cell biology, chemistry, biology.protein, Replisome, Proofreading, medicine.symptom, 030217 neurology & neurosurgery, DNA, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5584d9851ab733dd7d4154c96b1151a

المؤلفون: Aravind Natarajan, Jessica C. Stark, Jasmine M. Hershewe, Michael C. Jewett, James E. Kath, Jennifer A. Schoborg, Thapakorn Jaroentomeechai, Weston Kightlinger, Matthew P. DeLisa

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Glycan, Glycosylation, biology, 030302 biochemistry & molecular biology, biology.organism_classification, Campylobacter jejuni, carbohydrates (lipids), 03 medical and health sciences, Transmembrane domain, chemistry.chemical_compound, Synthetic biology, Enzyme, chemistry, Campylobacter lari, Biochemistry, Protein biosynthesis, biology.protein, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd59628d19e3a12a2d5dc0a2015373da

المؤلفون: Thapakorn Jaroentomeechai, Aravind Natarajan, Jessica C. Stark, Matthew P. DeLisa, Weston Kightlinger, James E. Kath, Jasmine M. Hershewe, Michael C. Jewett, Jennifer A. Schoborg

المصدر: Biotechnology and bioengineering. 115(3)

مصطلحات موضوعية: 0301 basic medicine, Glycan, Glycosylation, Bioengineering, Applied Microbiology and Biotechnology, Campylobacter jejuni, 03 medical and health sciences, chemistry.chemical_compound, Synthetic biology, Bacterial Proteins, Cell-free protein synthesis, 030102 biochemistry & molecular biology, biology, Cell-Free System, Chemistry, Oligosaccharyltransferase, Glycosyltransferases, Campylobacter, biology.organism_classification, carbohydrates (lipids), Transmembrane domain, 030104 developmental biology, Biochemistry, Membrane protein, biology.protein, Desulfovibrio, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2a4780c79e096aa696b5e28e6199f8
https://pubmed.ncbi.nlm.nih.gov/29178580

المؤلفون: James E. Kath, Mark D. Sutton, Joseph J. Loparo, Slobodan Jergic, Deena T. Jacob, Justin M. H. Heltzel, Nicholas E. Dixon, Graham C. Walker

المصدر: Proceedings of the National Academy of Sciences. 111:7647-7652

مصطلحات موضوعية: Multidisciplinary, DNA clamp, Models, Genetic, biology, DNA polymerase, DNA polymerase II, DNA replication, dnaN, DNA, Processivity, Biological Sciences, Microfluidic Analytical Techniques, DNA polymerase delta, Molecular biology, Statistics, Nonparametric, Cell biology, Escherichia coli, biology.protein, SOS Response, Genetics, DNA polymerase mu, DNA Polymerase beta, DNA Polymerase III, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca14188473de1a405e8a61798502978
https://doi.org/10.1073/pnas.1321076111

المؤلفون: Elizabeth S. Thrall, Joseph J. Loparo, James E. Kath

المصدر: Biophysical Journal. 110(3)

مصطلحات موضوعية: biology, DNA polymerase, DNA replication, biology.protein, Biophysics, Replisome, Base excision repair, Processivity, DNA polymerase delta, Molecular biology, RNA polymerase III, Polymerase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610c21688309d5d5f960f45400f71ecd

المؤلفون: Mark D. Sutton, Nicholas E. Dixon, Joseph J. Loparo, Seungwoo Chang, Slobodan Jergic, James E. Kath, Michelle K. Scotland, Johannes H. Wilbertz

المصدر: Nucleic Acids Research

مصطلحات موضوعية: 0301 basic medicine, DNA Replication, DNA Repair, DNA polymerase, DNA polymerase II, viruses, Genome Integrity, Repair and Replication, DNA polymerase delta, RNA polymerase III, 03 medical and health sciences, Genetics, Escherichia coli, DNA Polymerase beta, DNA Polymerase III, DNA clamp, biology, DNA replication, Base excision repair, Processivity, DNA, DNA Polymerase II, Molecular biology, Cell biology, Protein Structure, Tertiary, 030104 developmental biology, Multiprotein Complexes, biology.protein, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c39eafb5bc1b071f5b4a1d2e7edd0a
https://pubmed.ncbi.nlm.nih.gov/26657641

المؤلفون: Anthony J. Berdis, Jung Suk Choi, Joseph J. Loparo, Michelle K. Scotland, Justin M. H. Heltzel, James E. Kath, Mark D. Sutton

المصدر: PLoS Genetics, Vol 11, Iss 9, p e1005507 (2015)
PLoS Genetics

مصطلحات موضوعية: DNA Replication, Cancer Research, DNA Repair, lcsh:QH426-470, DNA polymerase, DNA repair, viruses, RNA polymerase III, Catalytic Domain, Genetics, Escherichia coli, Selection, Genetic, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, DNA Polymerase beta, DNA clamp, biology, Escherichia coli Proteins, DNA replication, Base excision repair, Processivity, Molecular biology, lcsh:Genetics, DNA polymerase IV, biology.protein, DNA Damage, Protein Binding, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8522fea00e1f978b350e2e5b9a866a6
http://europepmc.org/articles/PMC4564189?pdf=render

المؤلفون: Joseph J. Loparo, Slobodan Jergic, Deena T. Jacob, Nicholas E. Dixon, Graham C. Walker, Justin M. H. Heltzel, James E. Kath, Mark D. Sutton

المصدر: The FASEB Journal. 29

مصطلحات موضوعية: biology, Chemistry, DNA polymerase, media_common.quotation_subject, Genetics, Biophysics, biology.protein, Molecule, Molecular Biology, Biochemistry, Competition (biology), Biotechnology, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2e1d8a2e9331d13b46948e2f3fdf3014
https://doi.org/10.1096/fasebj.29.1_supplement.561.6

المؤلفون: Pallavi Ghosh, Felix Manuel Zörgiebel, Graham F. Hatfull, Hua Bai, Mingxuan Sun, Nigel D. F. Grindley, James E. Kath, John F. Marko

مصطلحات موضوعية: Substrate Specificity, chemistry.chemical_compound, Motion, Deoxyribonuclease I, Humans, Enzyme kinetics, chemistry.chemical_classification, Multidisciplinary, DNA, Superhelical, DNA, Biological Sciences, Transition state, Enzymes, Kinetics, Enzyme, chemistry, Biochemistry, DNA Topoisomerases, Type I, Models, Chemical, Brownian dynamics, Biophysics, Particle, Nucleic Acid Conformation, Algorithms, Macromolecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6cb195298607e0c0417ca9d47cd3df
https://europepmc.org/articles/PMC3478594/

المؤلفون: Felix Zorgebiel, Nigel D. F. Grindley, Hua Bai, James E. Kath, John F. Marko

المصدر: Biophysical Journal. 102(3)

مصطلحات موضوعية: chemistry.chemical_classification, Drag coefficient, Stereochemistry, Biophysics, Biology, Stress (mechanics), Coupling (electronics), chemistry.chemical_compound, Enzyme, chemistry, Nucleic acid, Particle, Molecule, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd37762353eac9e69852c651fed1944

المؤلفون: James E. Kath

المصدر: Biophysical Journal. 102:281a

مصطلحات موضوعية: chemistry.chemical_classification, Genetics, DNA synthesis, biology, DNA polymerase, Biophysics, RNA polymerase III, chemistry.chemical_compound, Enzyme, chemistry, biology.protein, Replisome, Polymerase, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d89706b91d0860cd2ac1f7cc88b95a
https://doi.org/10.1016/j.bpj.2011.11.1553