المؤلفون: Josephine Moran, Liam Feltham, James Bagnall, Marie Goldrick, Elizabeth Lord, Catherine Nettleton, David G. Spiller, Ian Roberts, Pawel Paszek

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: Listeria monocytogenes, macrophage, single cell heterogeneity, phagocytosis, PrfA regulon, listeriolysin, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1235675/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/69fdee6a62aa4abfa1029b6156b2163f

المؤلفون: Eirini Kalliara, Malgorzata Kardynska, James Bagnall, David G. Spiller, Werner Müller, Dominik Ruckerl, Jarosław Śmieja, Subhra K. Biswas, Pawel Paszek

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: JAK-STAT network, STAT1 kinetics, interferons, pathway desensitisation, mathematical modelling, signal memory, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.947213/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/f18214bc8b124365b6050d91ca9f4e00

المؤلفون: Anna Paszek, Małgorzata Kardyńska, James Bagnall, Jarosław Śmieja, David G. Spiller, Piotr Widłak, Marek Kimmel, Wieslawa Widlak, Pawel Paszek

المصدر: Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-21 (2020)

مصطلحات موضوعية: Heat-shock, HSF1, NF-kappaB signalling, IKK signalosome, Single-cell analyses, Live-cell imaging, Medicine, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12964-020-00583-0; https://doaj.org/toc/1478-811X

URL الوصول: https://doaj.org/article/758c2e93f16345e197d175e447dfcac2

المؤلفون: Nan Yang, Nicola J Smyllie, Honor Morris, Cátia F Gonçalves, Michal Dudek, Dharshika R J Pathiranage, Johanna E Chesham, Antony Adamson, David G Spiller, Egor Zindy, James Bagnall, Neil Humphreys, Judith Hoyland, Andrew S I Loudon, Michael H Hastings, Qing-Jun Meng

المصدر: PLoS Genetics, Vol 16, Iss 4, p e1008729 (2020)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/43fa25b09c644bd38b2e46c67b3637c5

المؤلفون: Michael J. D. Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G. Spencer, William Watremez, Victoria Fasolino, Sophie J. Booth, Claire S. White, Alex G. Baldwin, Sally Freeman, Raymond Wong, Clare Latta, Shi Yu, Joshua Jackson, Nicolas Fischer, Violette Koziel, Thierry Pillot, James Bagnall, Stuart M. Allan, Pawel Paszek, James Galea, Michael K. Harte, Claudia Eder, Catherine B. Lawrence, David Brough

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/dca8360eb57c4ee588985f6c192c8a0c

المؤلفون: Antony Adamson, Christopher Boddington, Polly Downton, William Rowe, James Bagnall, Connie Lam, Apolinar Maya-Mendoza, Lorraine Schmidt, Claire V. Harper, David G. Spiller, David A. Rand, Dean A. Jackson, Michael R. H. White, Pawel Paszek

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1d4f418033bb45d7b771ae8b6ba8118e

المؤلفون: Nick E Phillips, Cerys S Manning, Tom Pettini, Veronica Biga, Elli Marinopoulou, Peter Stanley, James Boyd, James Bagnall, Pawel Paszek, David G Spiller, Michael RH White, Marc Goodfellow, Tobias Galla, Magnus Rattray, Nancy Papalopulu

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: Hes1, stochasticity, molecular oscillations, miR-9, neural stem cells, single cell heterogeneity, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/16118; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/abe0521a88b64a059ce015c962daaea4

المؤلفون: Alkisti Manousaki, James Bagnall, David Spiller, Laura Natalia Balarezo-Cisneros, Michael White, Daniela Delneri

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8532

مصطلحات موضوعية: protein quantification, yeast, FCS, haplo-insufficiency, mitochondrial proteins

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms23158532

الاتاحة: https://doi.org/10.3390/ijms23158532

المؤلفون: Josephine Moran, Liam Feltham, James Bagnall, Marie Goldrick, Elizabeth Lord, Catherine Nettleton, David G. Spiller, Ian Roberts, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, Listeria monocytogenes, macrophage, single cell heterogeneity, phagocytosis, PrfA regulon, listeriolysin

Relation: https://figshare.com/articles/figure/Image_3_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_tiff/24003480

الاتاحة: https://doi.org/10.3389/fimmu.2023.1235675.s004
https://figshare.com/articles/figure/Image_3_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_tiff/24003480

المؤلفون: Josephine Moran, Liam Feltham, James Bagnall, Marie Goldrick, Elizabeth Lord, Catherine Nettleton, David G. Spiller, Ian Roberts, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, Listeria monocytogenes, macrophage, single cell heterogeneity, phagocytosis, PrfA regulon, listeriolysin

Relation: https://figshare.com/articles/media/Video_3_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_mp4/24003504

الاتاحة: https://doi.org/10.3389/fimmu.2023.1235675.s010
https://figshare.com/articles/media/Video_3_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_mp4/24003504

المؤلفون: Josephine Moran, Liam Feltham, James Bagnall, Marie Goldrick, Elizabeth Lord, Catherine Nettleton, David G. Spiller, Ian Roberts, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, Listeria monocytogenes, macrophage, single cell heterogeneity, phagocytosis, PrfA regulon, listeriolysin

Relation: https://figshare.com/articles/dataset/DataSheet_1_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_xlsx/24003465

الاتاحة: https://doi.org/10.3389/fimmu.2023.1235675.s001
https://figshare.com/articles/dataset/DataSheet_1_Live-cell_imaging_reveals_single-cell_and_population-level_infection_strategies_of_Listeria_monocytogenes_in_macrophages_xlsx/24003465

المؤلفون: Josephine Moran, Liam Feltham, James Bagnall, Marie Goldrick, Elizabeth Lord, Catherine Nettleton, David G. Spiller, Ian Roberts, Pawel Paszek

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::77ab32209874f342bdd6f0294dd3ff85
https://doi.org/10.1101/2022.06.04.493993

المؤلفون: Eirini Kalliara, Malgorzata Kardynska, James Bagnall, David G. Spiller, Werner Müller, Dominik Ruckerl, Jarosław Śmieja, Subhra K. Biswas, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, JAK-STAT network, STAT1 kinetics, interferons, pathway desensitisation, mathematical modelling, signal memory, live-cell microscopy

Relation: https://figshare.com/articles/dataset/DataSheet_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_pdf/21215078

الاتاحة: https://doi.org/10.3389/fimmu.2022.947213.s001
https://figshare.com/articles/dataset/DataSheet_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_pdf/21215078

المؤلفون: Eirini Kalliara, Malgorzata Kardynska, James Bagnall, David G. Spiller, Werner Müller, Dominik Ruckerl, Jarosław Śmieja, Subhra K. Biswas, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, JAK-STAT network, STAT1 kinetics, interferons, pathway desensitisation, mathematical modelling, signal memory, live-cell microscopy

Relation: https://figshare.com/articles/media/Video_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_mp4/21215084

الاتاحة: https://doi.org/10.3389/fimmu.2022.947213.s003
https://figshare.com/articles/media/Video_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_mp4/21215084

المؤلفون: Eirini Kalliara, Malgorzata Kardynska, James Bagnall, David G. Spiller, Werner Müller, Dominik Ruckerl, Jarosław Śmieja, Subhra K. Biswas, Pawel Paszek

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, JAK-STAT network, STAT1 kinetics, interferons, pathway desensitisation, mathematical modelling, signal memory, live-cell microscopy

Relation: https://figshare.com/articles/dataset/Table_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_xlsx/21215081

الاتاحة: https://doi.org/10.3389/fimmu.2022.947213.s002
https://figshare.com/articles/dataset/Table_1_Post-transcriptional_regulatory_feedback_encodes_JAK-STAT_signal_memory_of_interferon_stimulation_xlsx/21215081

المؤلفون: John Blaikley, Gareth B. Kitchen, Tracy Hussell, Mudassar Iqbal, Robert Maidstone, Laura Matthews, Hannah J. Durrington, Peter S. Cunningham, James Bagnall, Nicola Begley, Matthew Baxter, Ben Saer, Toryn Poolman, Julie E. Gibbs, Andrew S. I. Loudon, David W. Ray, David H. Dockrell

المصدر: Kitchen, G B, Cunningham, P S, Poolman, T M, Iqbal, M, Maidstone, R, Baxter, M, Bagnall, J, Begley, N, Saer, B, Hussell, T, Matthews, L C, Dockrell, D H, Durrington, H J, Gibbs, J E, Blaikley, J F, Loudon, A S & Ray, D W 2020, ' The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia ', Proceedings of the National Academy of Sciences, vol. 117, no. 3, pp. 1543-1551 . https://doi.org/10.1073/pnas.1915932117

مصطلحات موضوعية: endocrine system, actin cytoskeleton, RHOA, Disease Resistance/genetics, Circadian Clocks/genetics, Lydia Becker Institute, Phagocytosis/drug effects, Phagocytosis, Motility, Cell Movement/drug effects, Cell morphology, Mice, 03 medical and health sciences, Macrophages/drug effects, 0302 clinical medicine, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, rhoA GTP-Binding Protein/metabolism, Animals, Macrophage, Cytoskeleton, Actin, ARNTL Transcription Factors/antagonists & inhibitors, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Multidisciplinary, biology, Circadian, RhoA, Pneumonia, Pneumococcal/metabolism, Streptococcus pneumoniae/pathogenicity, Actin cytoskeleton, 3. Good health, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Streptococcus pneumoniae, Actins/metabolism, biology.protein, Female, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2f3ec07d41a024bb148b8e2b4eb0d7
https://doi.org/10.1073/pnas.1915932117

المؤلفون: John Blaikley, Andrew S. I. Loudon, Peter Meijer, Andrew J. Fisher, Karen Piper-Hanley, Neil C. Henderson, Alicja Nazgiewicz, Rajamayier V. Venkateswaran, Gareth B. Kitchen, Martin K. Rutter, James Bagnall, Rachel C. Chambers, Lee A. Borthwick, Boris Hinz, Nicola Begley, Peter S. Cunningham, Rajesh Shah, Julie E. Gibbs, David W. Ray, Simon G. Anderson, Monika Lodyga, Paul F. Mercer, David A. Bechtold, Hannah J. Durrington

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Cunningham, P, Meijer, P, Nazgiewicz, A, Anderson, S, Borthwick, L A, Bagnall, J, Kitchen, G, Lodyga, M, Begley, N, Venkateswaran, R, Shah, R, Mercer, P F, Durrington, H, Henderson, N, Piper Hanley, K, Fisher, A, Chambers, R C, Bechtold, D, Gibbs, J, Loudon, A, Rutter, M K, Hinz, B, Ray, D & Blaikley, J 2020, ' The circadian clock protein REVERBα inhibits pulmonary fibrosis development ', Proceedings of the National Academy of Sciences, vol. 117, no. 2, pp. 1139-1147 . https://doi.org/10.1073/pnas.1912109117
Cunningham, P S, Meijer, P, Nazgiewicz, A, Anderson, S G, Borthwick, L A, Bagnall, J, Kitchen, G B, Lodyga, M, Begley, N, Venkateswaran, R V, Shah, R, Mercer, P F, Durrington, H J, Henderson, N C, Piper-hanley, K, Fisher, A J, Chambers, R C, Bechtold, D A, Gibbs, J E, Loudon, A S, Rutter, M K, Hinz, B, Ray, D W & Blaikley, J F 2020, ' The circadian clock protein REVERBα inhibits pulmonary fibrosis development ', Proceedings of the National Academy of Sciences, vol. 117, no. 2, pp. 1139-1147 . https://doi.org/10.1073/pnas.1912109117

مصطلحات موضوعية: Male, Integrins, Medical Sciences, Circadian clock, CLOCK Proteins, Integrin, Mice, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, Pulmonary fibrosis, Myofibroblasts, Lung, Mice, Knockout, 0303 health sciences, Multidisciplinary, Circadian, Biological Sciences, Circadian Rhythm, 3. Good health, Gene Knockdown Techniques, medicine.symptom, Myofibroblast, Cell type, integrin, Inflammation, Bleomycin, 03 medical and health sciences, Circadian Clocks, medicine, Animals, Humans, Circadian rhythm, sleep, 030304 developmental biology, Reverb alpha, pulmonary fibrosis, business.industry, Mesenchymal Stem Cells, Fibroblasts, medicine.disease, Idiopathic Pulmonary Fibrosis, circadian, Gene Expression Regulation, chemistry, Cancer research, TATA Box Binding Protein-Like Proteins, Transcriptome, Sleep, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c7fdf84cedf5c0195bf8bff0f86ab4
https://doi.org/10.1073/pnas.1912109117

المؤلفون: Michael H. Hastings, Korbinian Strimmer, Andrew S. I. Loudon, Nicola J. Smyllie, Alex A. Koch, Thomas House, Nicola Begley, Carrie L. Partch, Antony Adamson, David G. Spiller, Qing-Jun Meng, Jennifer L. Fribourgh, James Bagnall

مصطلحات موضوعية: PER2, endocrine system, chemistry.chemical_compound, Chemistry, Gene expression, Circadian clock, Circadian rhythm, Gene, Psychological repression, DNA, Atomic clock, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::331ede3812dadd198d35b62e38ea7712
https://doi.org/10.1101/2021.08.27.456017

المؤلفون: Piotr Widlak, Marek Kimmel, Wieslawa Widlak, Paszek A, David G. Spiller, James Bagnall, Jarosław Śmieja, Malgorzata Kardynska, Pawel Paszek

مصطلحات موضوعية: Hyperthermia, Cytokine, Kinase, Chemistry, medicine.medical_treatment, medicine, Tumor necrosis factor alpha, Heat shock, Beta (finance), HSF1, medicine.disease, Transcription factor, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9647b831cb5cd2dc407aece0713e902e
https://doi.org/10.1101/782516

المؤلفون: Pawel Paszek, Christopher M. Clark, Dean A. Jackson, Nissrin Alachkar, James Bagnall, James Roberts, Mark Muldoon, Hazel England, Mark Platt, William Rowe

المصدر: Bagnall, J, Rowe, W, Alachkar, N, Roberts, J, England, H, Clark, C, Platt, M, Jackson, D, Muldoon, M & Paszek, P 2020, ' Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling ', Cell Systems, vol. 11, no. 3, pp. 300-314.e8 . https://doi.org/10.1016/j.cels.2020.08.007

مصطلحات موضوعية: Histology, stochastic gene expression, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), cellular heterogeneity, Gene expression, Humans, RNA, Messenger, Receptor, Gene, 030304 developmental biology, Transcriptional bursting, 0303 health sciences, Messenger RNA, Toll-like receptor, Toll-Like Receptors, Cell Biology, Models, Theoretical, Chromatin, Cell biology, IL-1β, TNF-α, transcriptional bursting, toll-like receptor, single-cell transcriptomics, 030217 neurology & neurosurgery, Signal Transduction, stochastic modeling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895227e99b0e9bf89e5f102871fee92e
https://doi.org/10.1016/j.cels.2020.08.007