المؤلفون: Zabulica, Mihaela, Srinivasan, Raghuraman C, Akcakaya, Pinar, Allegri, Gabriella, Bestas, Burcu, Firth, Mike, Hammarstedt, Christina, Jakobsson, Tomas, Jakobsson, Towe, Ellis, Ewa, Jorns, Carl, Makris, Georgios, Scherer, Tanja, Rimann, Nicole, van Zuydam, Natalie R, Gramignoli, Roberto, Forslöw, Anna, Engberg, Susanna, Maresca, Marcello, Rooyackers, Olav, Thöny, Beat, Häberle, Johannes, Rosen, Barry, Strom, Stephen C

المصدر: Zabulica, Mihaela; Srinivasan, Raghuraman C; Akcakaya, Pinar; Allegri, Gabriella; Bestas, Burcu; Firth, Mike; Hammarstedt, Christina; Jakobsson, Tomas; Jakobsson, Towe; Ellis, Ewa; Jorns, Carl; Makris, Georgios; Scherer, Tanja; Rimann, Nicole; van Zuydam, Natalie R; Gramignoli, Roberto; Forslöw, Anna; Engberg, Susanna; Maresca, Marcello; Rooyackers, Olav; Thöny, Beat; Häberle, Johannes; Rosen, Barry; Strom, Stephen C (2021). Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes. Molecular Therapy, 29(5):1903-1917.

مصطلحات موضوعية: Medical Clinic, 610 Medicine & health, Molecular Medicine, Genetics, Molecular Biology, Pharmacology, Drug Discovery

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/198720/8/PIIS1525001621000241.pdf; info:pmid/33484963; urn:issn:1525-0016

الاتاحة: https://www.zora.uzh.ch/id/eprint/198720/
https://www.zora.uzh.ch/id/eprint/198720/8/PIIS1525001621000241.pdf
https://doi.org/10.1016/j.ymthe.2021.01.024

المؤلفون: Huang, Zhiqiang, Liang, Ning, Goñi, Saioa, Damdimopoulos, Anastasios, Wang, Cheng, Ballaire, Raphaelle, Jager, Jennifer, Niskanen, Henri, Han, Hongya, Jakobsson, Tomas, Bracken, Adrian, P, Aouadi, Myriam, Venteclef, Nicolas, Kaikkonen, Minna, U, Fan, Rongrong, Treuter, Eckardt

المساهمون: Karolinska Institutet Stockholm, Trinity College Dublin, University of Eastern Finland, Karolinska University Hospital Stockholm, Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)

المصدر: ISSN: 1097-2765.

مصطلحات موضوعية: GPS2, SMRT, chromatin remodeling, corepressor, eRNA, enhancer, epigenetics, inflammation, macrophage, silencer, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/33503407; hal-03124222; https://hal.sorbonne-universite.fr/hal-03124222; https://hal.sorbonne-universite.fr/hal-03124222/document; https://hal.sorbonne-universite.fr/hal-03124222/file/1-s2.0-S1097276520309618-main.pdf; PUBMED: 33503407

الاتاحة: https://hal.sorbonne-universite.fr/hal-03124222
https://hal.sorbonne-universite.fr/hal-03124222/document
https://hal.sorbonne-universite.fr/hal-03124222/file/1-s2.0-S1097276520309618-main.pdf
https://doi.org/10.1016/j.molcel.2020.12.040

المؤلفون: Liang, Ning, Damdimopoulos, Anastasius, Goñi, Saioa, Huang, Zhiqiang, Vedin, Lise-Lotte, Jakobsson, Tomas, Giudici, Marco, Ahmed, Osman, Pedrelli, Matteo, Barilla, Serena, Alzaid, Fawaz, Mendoza, Arturo, Schröder, Tarja, Kuiper, Raoul, Parini, Paolo, Hollenberg, Anthony, Lefebvre, Philippe, Francque, Sven, van Gaal, Luc, Staels, Bart, Venteclef, Nicolas, Treuter, Eckardt, Fan, Rongrong

المساهمون: Karolinska Institutet Stockholm, Department of Laboratory Medicine Karolinska Institutet, Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Weill Medical College of Cornell University New York, Inflammation and Infection Theme Karolinska University Hospital, Karolinska University Hospital Stockholm, Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Department of Gastroenterology and Hepatology, University of Antwerp (UA), Laboratory of Experimental Medicine and Pediatrics, Department of Endocrinology, Diabetology and Metabolism, E.T. was supported by grants from the Center for Innovative Medicine (CIMED) at the Karolinska Institutet, the Swedish Research Council, the Swedish Cancer Society, the Swedish Diabetes Foundation, the Novo Nordisk Foundation, and the European Union FP7 HEALTH project HUMAN. R.F. was supported by the European Foundation for the Study of Diabetes (EFSD)/Lilly research fellowship, Junior Diabetes Wellness Sverige grant and KI research foundation grants. R.K. and T.S. were supported by KI/SL and grants from CIMED. N.L. received a doctoral education grant (KID) from Karolinska Institutet. Z.H. was supported by Chinese Government Scholarship (CSC). N.V. was supported by grants from the French National Agency of Research (CONRAD and PROVIDE), Region Ile de France (CORDDIM), Paris city (EMERGENCE), the French Foundation for Diabetes (SFD), and the European Union H2020 framework (ERC-EpiFAT 725790). The human liver transcriptome study performed by P.L., F.A., N.V., and B.S. was supported by EU HEPADIP (Contract LSHM-CT-2005-018734) and RESOLVE (Contract FP7-305707) , the European Research Council (ERC Grant Immunobile, contract 694717), Fondation pour la Recherche Médicale (Equipe labellisée, DEQ20150331724) and Agence Nationale pour la Recherche (ANR-10-LBEX-46). B.S. is a recipient of an Advanced ERC Grant (694717), ANR-12-JSV1-0007,CONRAD,Le complexe répresseur SMRT-GPS2: senseur moléculaire de l'inflammation du tissu adipeux dans l'obésité humaine(2012), ANR-15-CE14-0029,PROVIDE,Compréhension des mécanismes inflammatoires protecteurs dans le diabète(2015), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: MESH: Animals, MESH: Biopsy, MESH: Non-alcoholic Fatty Liver Disease, MESH: PPAR alpha, MESH: Datasets as Topic, MESH: Diet, High-Fat, MESH: Disease Models, Animal, MESH: Disease Progression, MESH: Epigenesis, Genetic, MESH: Fibrosis, MESH: HEK293 Cells, MESH: Hepatocytes, MESH: Humans, MESH: Intracellular Signaling Peptides and Proteins, MESH: Lipid Metabolism, MESH: Liver, MESH: Male, MESH: Mice, Inbred C57BL, Knockout, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/30975991; info:eu-repo/grantAgreement//694717/EU/Bile acid, immune-metabolism, lipid and glucose homeostasis/ImmunoBile; PUBMED: 30975991; PUBMEDCENTRAL: PMC6459876

الاتاحة: https://inserm.hal.science/inserm-02154801
https://inserm.hal.science/inserm-02154801v1/document
https://inserm.hal.science/inserm-02154801v1/file/Liang%20Nat%20Commun.pdf
https://doi.org/10.1038/s41467-019-09524-z

المؤلفون: Fontana, Raffaella, Raccosta, Laura, Rovati, Lucrezia, Steffensen, Knut R., Paniccia, Aida, Jakobsson, Tomas, Melloni, Giulio, Bandiera, Alessandro, Mangili, Giorgia, Bergamini, Alice, Maggioni, Daniela, Doglioni, Claudio, Crocchiolo, Roberto, Cella, Marina, Mattioli, Michela, Battaglia, Cristina, Colonna, Marco, Russo, Vincenzo

المساهمون: R. Fontana, L. Raccosta, L. Rovati, K.R. Steffensen, A. Paniccia, T. Jakobsson, G. Melloni, A. Bandiera, G. Mangili, A. Bergamini, D. Maggioni, C. Doglioni, R. Crocchiolo, M. Cella, M. Mattioli, C. Battaglia, M. Colonna, V. Russo

مصطلحات موضوعية: dendritic cell, lung cancer, LXR nuclear receptor, ovarian cancer, RAR/RXR nuclear receptor, TREM-1, Immunology and Allergy, Immunology, Oncology, Settore BIO/10 - Biochimica

Relation: info:eu-repo/semantics/altIdentifier/pmid/30723587; info:eu-repo/semantics/altIdentifier/wos/WOS:000457625200014; volume:8; issue:3; firstpage:1; lastpage:17; numberofpages:17; journal:ONCOIMMUNOLOGY; http://hdl.handle.net/2434/627038; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85058711045

الاتاحة: http://hdl.handle.net/2434/627038
https://doi.org/10.1080/2162402X.2018.1554967

المؤلفون: Liang, Ning, Damdimopoulos, Anastasius, Goni, Saioa, Huang, Zhiqiang, Vedin, Lise-Lotte, Jakobsson, Tomas, Giudici, Marco, Ahmed, Osman, Pedrelli, Matteo, Barilla, Serena, Alzaid, Fawaz, Mendoza, Arturo, Schroder, Tarja, Kuiper, Raoul, Parini, Paolo, Hollenberg, Anthony, Lefebvre, Philippe, Francque, Sven, Van Gaal, Luc, Staels, Bart, Venteclef, Nicolas, Treuter, Eckardt, Fan, Rongrong

المصدر: 2041-1723 ; Nature communications

مصطلحات موضوعية: Engineering sciences. Technology

وصف الملف: pdf

Relation: info:eu-repo/semantics/altIdentifier/isi/000464093800015

الاتاحة: https://hdl.handle.net/10067/1593440151162165141
https://repository.uantwerpen.be/docman/irua/c5778d/159344.pdf

المؤلفون: Liang, Ning, Jakobsson, Tomas, Fan, Rongrong, Treuter, Eckardt

المساهمون: Vetenskapsrådet, Cancerfonden, Novo Nordisk Fonden, Diabetesfonden

المصدر: Frontiers in Endocrinology ; volume 10 ; ISSN 1664-2392

الاتاحة: http://dx.doi.org/10.3389/fendo.2019.00411
https://www.frontiersin.org/article/10.3389/fendo.2019.00411/full

المؤلفون: Fontana, Raffaella, Raccosta, Laura, Rovati, Lucrezia, Steffensen, Knut R., Paniccia, Aida, Jakobsson, Tomas, Melloni, Giulio, Bandiera, Alessandro, Mangili, Giorgia, Bergamini, Alice, Maggioni, Daniela, Doglioni, Claudio, Crocchiolo, Roberto, Cella, Marina, Mattioli, Michela, Battaglia, Cristina, Colonna, Marco, Russo, Vincenzo

المساهمون: Associazione Italiana per la Ricerca sul Cancro, Fondazione Umberto Veronesi, Ministero della Salute

المصدر: OncoImmunology ; volume 8, issue 3, page 1554967 ; ISSN 2162-402X

الاتاحة: http://dx.doi.org/10.1080/2162402x.2018.1554967
https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2018.1554967

المؤلفون: Treuter, Eckardt, Fan, Rongrong, Huang, Zhiqiang, Jakobsson, Tomas, Venteclef, Nicolas

المساهمون: Karolinska Institutet, Vetenskapsrådet, Cancerfonden, Novo Nordisk, Agence Nationale de la Recherche

المصدر: FEBS Letters ; volume 591, issue 19, page 2959-2977 ; ISSN 0014-5793 1873-3468

الاتاحة: http://dx.doi.org/10.1002/1873-3468.12850
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F1873-3468.12850
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.12850

المؤلفون: Jakobsson, Tomas, Vedin, Lise-Lotte, Parini, Paolo

المصدر: Drugs ; volume 77, issue 15, page 1613-1621 ; ISSN 0012-6667 1179-1950

الاتاحة: http://dx.doi.org/10.1007/s40265-017-0791-4
http://link.springer.com/article/10.1007/s40265-017-0791-4/fulltext.html
http://link.springer.com/content/pdf/10.1007/s40265-017-0791-4.pdf

المؤلفون: Jakobsson, Tomas

وصف الملف: electronic

URL الوصول: http://hdl.handle.net/10616/40631

المؤلفون: Zabulica, Mihaela, Jakobsson, Tomas, Ravaioli, Francesco, Vosough, Massoud, Gramignoli, Roberto, Ellis, Ewa, Rooyackers, Olav, Strom, Stephen C.

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1217, p 1217 (2021)

مصطلحات موضوعية: Induced Pluripotent Stem Cells, Models, Biological, Article, lcsh:Chemistry, urea cycle, Humans, Urea, genome editing, lcsh:QH301-705.5, Cells, Cultured, Genetic Association Studies, Gene Editing, iPSC, Gene Expression Profiling, Stem Cells, Genetic Variation, Cell Differentiation, Immunohistochemistry, disease modelling, Organoids, lcsh:Biology (General), lcsh:QD1-999, CRISPR, hepatocytes, Disease Susceptibility, CRISPR-Cas Systems, Biomarkers, Metabolic Networks and Pathways

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a7b03f534e6cc1a92366e9e2362171b2

المؤلفون: Venteclef, Nicolas, Jakobsson, Tomas, Ehrlund, Anna, Damdimopoulos, Anastasios, Mikkonen, Laura, Ellis, Ewa, Nilsson, Lisa-Mari, Parini, Paolo, Jänne, Olli A., Gustafsson, Jan-Åke, Steffensen, Knut R., Treuter, Eckardt

مصطلحات موضوعية: Research Papers

وصف الملف: text/html

Relation: http://genesdev.cshlp.org/cgi/content/short/24/4/381; http://dx.doi.org/10.1101/gad.545110

الاتاحة: http://genesdev.cshlp.org/cgi/content/short/24/4/381
https://doi.org/10.1101/gad.545110

المؤلفون: Jakobsson, Tomas, Venteclef, Nicolas, Toresson, Gudrun, Damdimopoulos, Anastasios E., Ehrlund, Anna, Lou, Xiaohua, Sanyal, Sabyasachi, Steffensen, Knut R., Gustafsson, Jan-Åke, Treuter, Eckardt

المصدر: Molecular Cell ; volume 34, issue 4, page 510-518 ; ISSN 1097-2765

الاتاحة: http://dx.doi.org/10.1016/j.molcel.2009.05.006
https://api.elsevier.com/content/article/PII:S1097276509003141?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1097276509003141?httpAccept=text/plain

المؤلفون: Antonson, Per, Jakobsson, Tomas, Almlöf, Tova, Guldevall, Karolin, Steffensen, Knut R., Gustafsson, Jan-Åke

المصدر: Journal of Biological Chemistry ; volume 283, issue 14, page 8995-9001 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m707203200
https://api.elsevier.com/content/article/PII:S0021925820528652?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820528652?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M707203200

المؤلفون: Alzaïd, Fawaz, Jakobsson, Tomas, Treuter, Eckardt, Venteclef, Nicolas

المصدر: Handbook of Nutrition, Diet, and Epigenetics ; page 233-263 ; ISBN 9783319555294 9783319555300

الاتاحة: http://dx.doi.org/10.1007/978-3-319-55530-0_116
http://link.springer.com/content/pdf/10.1007/978-3-319-55530-0_116

المؤلفون: Jakobsson, Tomas, Osman, Waffa, Gustafsson, Jan-Åke, Zilliacus, Johanna, Wärnmark, Anette

المساهمون: Department of Biosciences and Nutrition, Karolinska Institutet Stockholm

المصدر: ISSN: 0264-6021.

مصطلحات موضوعية: Life Sciences

Relation: hal-00478730; https://hal.archives-ouvertes.fr/hal-00478730; https://hal.archives-ouvertes.fr/hal-00478730/document; https://hal.archives-ouvertes.fr/hal-00478730/file/PEER_stage2_10.1042%252FBJ20070004.pdf

الاتاحة: https://hal.archives-ouvertes.fr/hal-00478730
https://hal.archives-ouvertes.fr/hal-00478730/document
https://hal.archives-ouvertes.fr/hal-00478730/file/PEER_stage2_10.1042%252FBJ20070004.pdf
https://doi.org/10.1042/BJ20070004

المؤلفون: Pramfalk, Camilla, Jakobsson, Tomas, Verzijl, Cristy R.C., Minniti, Mirko E., Obensa, Clara, Ripamonti, Federico, Olin, Maria, Pedrelli, Matteo, Eriksson, Mats, Parini, Paolo

المساهمون: Swedish Research Council, Swedish Heart-Lung Foundation, Stockholm City Council, Karolinska Institutet

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ; volume 1865, issue 6, page 158659 ; ISSN 1388-1981

الاتاحة: http://dx.doi.org/10.1016/j.bbalip.2020.158659
https://api.elsevier.com/content/article/PII:S1388198120300512?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1388198120300512?httpAccept=text/plain

المؤلفون: Santinha, Deolinda, Klopot, Anna, Marques, Igor, Ellis, Ewa, Jorns, Carl, Johansson, Helene, Melo, Tânia, Antonson, Per, Jakobsson, Tomas, Félix, Vítor, Gustafsson, Jan-Åke, Domingues, Maria Rosário, Mode, Agneta, Helguero, Luisa A.

المصدر: The Journal of Steroid Biochemistry and Molecular Biology ; volume 198, page 105558 ; ISSN 0960-0760

الاتاحة: http://dx.doi.org/10.1016/j.jsbmb.2019.105558
https://api.elsevier.com/content/article/PII:S0960076019302882?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960076019302882?httpAccept=text/plain

المؤلفون: Alzaïd, Fawaz, Jakobsson, Tomas, Treuter, Eckardt, Venteclef, Nicolas

المصدر: Handbook of Nutrition, Diet, and Epigenetics ; page 1-31 ; ISBN 9783319311432 9783319311432

الاتاحة: http://dx.doi.org/10.1007/978-3-319-31143-2_116-1
http://link.springer.com/content/pdf/10.1007/978-3-319-31143-2_116-1

المؤلفون: Venteclef, Nicolas, Jakobsson, Tomas, Treuter, Eckardt

المصدر: Compendium of Inflammatory Diseases ; page 994-1016 ; ISBN 9783764385309 9783764385507

الاتاحة: http://dx.doi.org/10.1007/978-3-7643-8550-7_207
http://link.springer.com/content/pdf/10.1007/978-3-7643-8550-7_207