المؤلفون: Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::22628225105d10e01b1823421dc49781
https://doi.org/10.1158/1535-7163.c.6536578.v1

المؤلفون: Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b26de16f0ee5d751321264d9d15621d
https://doi.org/10.1158/1535-7163.22498848

المؤلفون: Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b531576d023873277f8bbc6e15fa91
https://doi.org/10.1158/1535-7163.22498851

المؤلفون: Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22324d5e3fb3ac4e9a4d4c1e89f1bae3
https://doi.org/10.1158/1535-7163.22500817.v1

المؤلفون: Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32264138e74601170f5f533f626867e
https://doi.org/10.1158/1535-7163.22500811.v1

المؤلفون: Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb62eb48bfbf19159c380c73cb9da0d
https://doi.org/10.1158/1535-7163.22500105.v1

المؤلفون: Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b0837c46c6fb9854d5f51893366d9a
https://doi.org/10.1158/1535-7163.22498845.v1

المؤلفون: Sheng-Bin Peng, Richard P. Beckmann, James J. Starling, Edward M. Chan, Sean G. Buchanan, Youyan Zhang, Robert D. Van Horn, Lysiane Huber, Teresa F. Burke, Vipin Yadav

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bd36236a130dcd815e4329a2a4012f
https://doi.org/10.1158/1535-7163.22501512.v1

المؤلفون: Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d956222196f28eb3db5494e81e7cc02
https://doi.org/10.1158/1535-7163.22500814.v1

المؤلفون: Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70fa29c964bb208bbfee904a5d0548e
https://doi.org/10.1158/1535-7163.22500102

المؤلفون: Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b805b19504f4ca7d3dd3ca23723e6c77
https://doi.org/10.1158/1535-7163.c.6536355

المؤلفون: Sheng-Bin Peng, Gregory D. Plowman, James J. Starling, James R. Henry, Ilaria Conti, Lysiane Huber, Yong Gang Yue, Swee Seong Wong, Igor Mochalkin, Vipin Yadav, Sean Buchanan, Tinggui Yin, Robert D. Van Horn, Youyan Zhang, Shih-Hsun Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436628872cb0b1f40e19a206dbd41888
https://doi.org/10.1158/2159-8290.22531479

المؤلفون: Bmc Genomics, Yuefeng Chen, Tao Wei, Lei Yan, Frank Lawrence, Hui-rong Qian, Timothy P Burkholder, James J Starling, Jonathan M Yingling, Jianyong Shou

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d5/47/BMC_Genomics_2008_Jun_2_9_264.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.6318

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.6318

المؤلفون: Ilaria Conti, Sheng-Bin Peng, James J. Starling, Igor Mochalkin, Henry James Robert, Sean Buchanan, Robert D. Van Horn, Lysiane Huber, Gregory D. Plowman, Swee Seong Wong, Youyan Zhang, Vipin Yadav, Yong Gang Yue, Shih-Hsun Chen, Tinggui Yin

المصدر: Cancer Discovery. 6:300-315

مصطلحات موضوعية: Models, Molecular, Proto-Oncogene Proteins B-raf, 0301 basic medicine, MAPK/ERK pathway, endocrine system diseases, MAP Kinase Signaling System, Protein Conformation, Gene Expression, Antineoplastic Agents, Biology, medicine.disease_cause, Ectopic Gene Expression, Mice, 03 medical and health sciences, Cell Line, Tumor, Pancreatic cancer, medicine, Animals, Humans, Protein Interaction Domains and Motifs, skin and connective tissue diseases, Vemurafenib, Protein Kinase Inhibitors, neoplasms, Cell growth, Phenylurea Compounds, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Molecular biology, digestive system diseases, Disease Models, Animal, enzymes and coenzymes (carbohydrates), Cell Transformation, Neoplastic, Pyrimidines, 030104 developmental biology, Oncology, Protein kinase domain, Drug Resistance, Neoplasm, Cancer research, KRAS, Protein Multimerization, Gene Deletion, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9df17f6f1a5156205a0c57a556fafec
https://doi.org/10.1158/2159-8290.cd-15-0896

المؤلفون: Bryan D. Smith, Xiwen Ma, Ilaria Conti, Daniel L. Flynn, Yue Webster, Subha Vogeti, Xiaoyi Zhang, Lisa Kays, Robert D. Van Horn, Phenil J. Patel, Youyan Zhang, Gregory P. Donoho, Shih-Hsun Chen, Sean Buchanan, Lawrence Chun, Lysiane Huber, Thomas J. Rutkoski, Tinggui Yin, Vipin Yadav, Denis J. McCann, Igor Mochalkin, Gregory D. Plowman, Henry James Robert, James J. Starling, Jennie L. Walgren, Sheng-Bin Peng, Wei-Ping Lu, Michael Kaufman, Xueqian Gong, Scott C. Wise

المصدر: Cancer Cell. 28:384-398

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, MAPK/ERK pathway, Cancer Research, endocrine system diseases, MAP Kinase Signaling System, Antineoplastic Agents, Cell Line, Tumor, Neoplasms, medicine, Humans, Protein Isoforms, Phosphorylation, Kinase activity, Vemurafenib, Protein Kinase Inhibitors, neoplasms, Chemistry, Phenylurea Compounds, Dabrafenib, Cell Biology, Molecular biology, digestive system diseases, Proto-Oncogene Proteins c-raf, enzymes and coenzymes (carbohydrates), Pyrimidines, Oncology, Mutation, ras Proteins, Cancer research, Mitogen-Activated Protein Kinases, ARAF, Dimerization, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379b4cb9cd03085b2f838a879bfaa16a
https://doi.org/10.1016/j.ccell.2015.08.002

المؤلفون: Kevin Robert Fales, Emiko L. Kreklau, Graham N. Wishart, Bart W. Halstead, Shuyu Li, Tinggui Yin, Alfonso De Dios, Robert T. Foreman, Raquel Torrres, Timothy I. Meier, Sean E. Sissons, Aimee B. Lin, Rose T. Ajamie, Richard B. Gaynor, Xiang S. Ye, Damien M. Cronier, Maria Jose Lallena, Yue-Wei Qian, Gregory P. Donoho, Song Wu, Phillip W Iversen, Amit Aggarwal, Santiago Carballares, Jian Du, James J. Starling, Douglas J. Zeckner

المصدر: Molecular Cancer Therapeutics. 13:1442-1456

مصطلحات موضوعية: Cancer Research, Indazoles, Chronic lymphocytic leukemia, Antineoplastic Agents, Apoptosis, RNA polymerase II, Cell Line, Tumor, Serine, medicine, Humans, MCL1, Phosphorylation, Cyclohexylamines, Leukemia, biology, Kinase, Myeloid leukemia, Cancer, medicine.disease, Cyclin-Dependent Kinase 9, enzymes and coenzymes (carbohydrates), Oncology, Immunology, Cancer research, biology.protein, Myeloid Cell Leukemia Sequence 1 Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d9a575dfcb90b4735766d28d4f8e14
https://doi.org/10.1158/1535-7163.mct-13-0849

المؤلفون: Courtney M. Tate, Enrique Jambrina, Harold B. Brooks, Raymond Gilmour, Yong Wang, Jeremy R. Graff, Bryan D. Anderson, Stephen Parsons, Juan A. Velasco, Susan E. Pratt, Edward M. Chan, Songqing Na, Mary M. Mader, James J. Starling, Nathan A. Brooks, Robert M. Campbell, Alfonso De Dios, Louis Stancato, Xiang S. Ye, Denis J. McCann, Chuan Shih

المصدر: Molecular Cancer Therapeutics. 13:364-374

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Pyridines, p38 mitogen-activated protein kinases, Blotting, Western, Melanoma, Experimental, Pharmacology, p38 Mitogen-Activated Protein Kinases, Cell Line, HeLa, Mice, Adenosine Triphosphate, In vivo, Cell Line, Tumor, Neoplasms, Animals, Humans, Interleukin 8, Phosphorylation, Cells, Cultured, Tumor microenvironment, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, biology, Macrophages, Imidazoles, biology.organism_classification, Xenograft Model Antitumor Assays, Treatment Outcome, Oncology, Cancer cell, Cytokines, RNA Interference, Tumor necrosis factor alpha, Anisomycin, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f320ef68b5c49f221ffe773c0f0cce
https://doi.org/10.1158/1535-7163.mct-13-0513

المؤلفون: Henry James Robert, Shawn T. Estrem, Shuyu Li, Xiaoyi Zhang, Vipin Yadav, Sheng-Bin Peng, James J. Starling, Xueqian Gong, Sean Buchanan, Jiangang Liu

المصدر: Journal of Biological Chemistry. 287:28087-28098

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, MAPK/ERK pathway, Indoles, MAP Kinase Signaling System, Mutation, Missense, Biochemistry, Cell Line, Tumor, Anti-apoptotic Ras signalling cascade, medicine, Humans, Receptor, Fibroblast Growth Factor, Type 3, Vemurafenib, Melanoma, Molecular Biology, Sulfonamides, biology, Molecular Bases of Disease, Cell Biology, Fibroblast growth factor receptor 3, medicine.disease, Enzyme Activation, Amino Acid Substitution, Drug Resistance, Neoplasm, Tumor progression, Mitogen-activated protein kinase, Immunology, ras Proteins, biology.protein, Cancer research, V600E, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6754d410a45f3ee78b0dce344f17593f
https://doi.org/10.1074/jbc.m112.377218

المؤلفون: Philip W. Iversen, Joseph A. Jakubowski, James J. Starling, Lorrene A. Buckley, Mary Pat Knadler, Atsushi Sanbuissho

المصدر: International Journal of Toxicology. 31:317-325

مصطلحات موضوعية: Blood Platelets, Male, Prasugrel, Thienopyridine, Drug Evaluation, Preclinical, Thiophenes, Pharmacology, Toxicology, Piperazines, Adenoma, Liver Cell, Mice, P2Y12, Risk Factors, Cell Line, Tumor, medicine, Animals, Humans, Platelet activation, Cell Proliferation, Mice, Inbred ICR, Prasugrel Hydrochloride, Cell growth, business.industry, Liver Neoplasms, Xenograft Model Antitumor Assays, Rats, Inbred F344, Rats, Cell culture, Carcinogens, Platelet aggregation inhibitor, Female, business, Platelet Aggregation Inhibitors, DNA Damage, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ae432d900c01ac7e6508604a7570a1
https://doi.org/10.1177/1091581812445073

المؤلفون: Yangwei J. Pu, Everett J. Perkins, William D. Diseroad, David M. Bender, Anne H. Dantzig, Jeffrey A. Peterson, Deyi Zhang, Jingqi Bao, Kevin L. Law, Radhe K. Vaid, Nicholas A. Magnus, David Michael Remick, Mccarthy James R, Gregory A. Stephenson, Susan M. Reutzel-Edens, James J. Starling

المصدر: Journal of Medicinal Chemistry. 52:6958-6961

مصطلحات موضوعية: Models, Molecular, medicine.medical_treatment, Molecular Conformation, Administration, Oral, Antineoplastic Agents, Cytidine, Pharmacology, Crystallography, X-Ray, Deoxycytidine, Chemical synthesis, Mice, Intestinal mucosa, Oral administration, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Prodrugs, Chemotherapy, Chemistry, Biological activity, Prodrug, Gemcitabine, Bioavailability, Cell Transformation, Neoplastic, Solubility, Biochemistry, Colonic Neoplasms, Molecular Medicine, Crystallization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6826ce1900e7d8561ae2eb5ee2eacd99
https://doi.org/10.1021/jm901181h