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المؤلفون: Shabih Shakeel, Christopher J. Russo, Gianluca Degliesposti, Pablo Alcón, Eeson Rajendra, J.M. Skehel, Ketan J. Patel, Sarah L. Maslen, Carol V. Robinson, Chris H. Hill, Dror S. Chorev, Francis J. O’Reilly, Juri Rappsilber, Shaoda He, Sjors H.W. Scheres, Lori A. Passmore
المصدر: Shakeel, S, Rajendral, E, Alcón, P, O’Reilly, F J, Chorev, D S, Maslen, S, Degliesposti, G, Russo, C J, He, S, Hill, C H, Skehel, J M, Scheres, S H W, Patel, K J, Rappsilber, J, Robinson, C V & Passmore, L A 2019, ' Structure of the fanconi anaemia monoubiquitin ligase complex ', Nature, vol. 575, pp. 234-237 . https://doi.org/10.1038/s41586-019-1703-4
Natureمصطلحات موضوعية: Models, Molecular, Protein subunit, Fanconi Anemia Complementation Group L Protein, medicine.disease_cause, Article, Mass Spectrometry, Ligases, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, FANCD2, Ring finger, medicine, Humans, Animals, FANCL, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Mutation, Multidisciplinary, biology, Fanconi Anemia Complementation Group D2 Protein, Cryoelectron Microscopy, Ubiquitination, Fanconi Anemia Complementation Group Proteins, Ubiquitin ligase, Cell biology, FANCB, Protein Subunits, Fanconi Anemia, medicine.anatomical_structure, chemistry, Multiprotein Complexes, biology.protein, Protein Multimerization, Chickens, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Bettina Böttcher, M. Wingender, Sebastian Geibel, Gianluca Degliesposti, Andreas Schlosser, Angel Rivera-Calzada, J.M. Skehel, Rafael Fernandez-Leiro, Oscar Llorca, N. Famelis, Nicole Mietrach
المصدر: Nature
مصطلحات موضوعية: Models, Molecular, Mycobacterium smegmatis, Thermomonospora, Protein domain, Virulence, Article, Structure-Activity Relationship, 03 medical and health sciences, Adenosine Triphosphate, Protein structure, Protein Domains, Secretion, Protein Structure, Quaternary, 030304 developmental biology, Adenosine Triphosphatases, 0303 health sciences, Multidisciplinary, biology, 030306 microbiology, Chemistry, Cryoelectron Microscopy, Periplasmic space, biology.organism_classification, Cell biology, Actinobacteria, Protein Subunits, Membrane protein, Type VII Secretion Systems, Domain of unknown function
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المصدر: ESMO Open. 3:A24-A25
مصطلحات موضوعية: Cancer Research, Methyltransferase, Arginine, biology, Chemistry, DNA damage, RAD51, Wild type, Methylation, Cell biology, Deubiquitinating enzyme, Oncology, Ubiquitin, biology.protein