المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/journal_contribution/Quality_control_metrics_for_each_biological_replicate_/17710109

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.s001

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/journal_contribution/Cell_type_assignment_of_clusters_/17710112

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.s002

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/journal_contribution/Supplementary_methods_/17710121

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.s005

المؤلفون: Dong Hao Wang (3188649), Hui Gyu Park (7360718), Zhen Wang (72451), R. J. Scott Lacombe (10893443), Vadim V. Shmanai (1754725), Andrei V. Bekish (1854985), Karsten Schmidt (9997), Mikhail S. Shchepinov (1854982), J. Thomas Brenna (63512)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Biotechnology, Developmental Biology, Plant Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, EPA, allylic D-HUFA production, methyl end deuterates, allylic position, D 9-11 DHA, allylic D isotopologues, bi, Sodiated PB D-HUFA result, isotopomer-specific D composition, Unsaturated Hydrocarbon Chains, CID, allylic positions, isotopologues D 5-7 linolenic acid, D 9-11 docosahexaenoic acid, ARA

Relation: https://figshare.com/articles/journal_contribution/Toward_Quantitative_Sequencing_of_Deuteration_of_Unsaturated_Hydrocarbon_Chains_in_Fatty_Acids/14700176

الاتاحة: https://doi.org/10.1021/acs.analchem.1c01016.s001

المؤلفون: Dong Hao Wang (3188649), Zhen Wang (72451), Raymond Chen (1588603), K. S. D. Kothapalli (8905667), J. Thomas Brenna (63512)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Biotechnology, Ecology, Sociology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chia Seeds, 32 mg BCFA, three-ion monitoring method, Long-Chain Branched-Chain Fatty Acids, anteiso levels, long-chain BCFA, prebiotic role, Plant-derived BCFA, hair functionality, VLC BCFA, plant oils, Few studies, chia seed oil, branch position, nonfermented plant-derived BCFA, Topical administration

Relation: https://figshare.com/articles/journal_contribution/Very_Long-Chain_Branched-Chain_Fatty_Acids_in_Chia_Seeds_Implications_for_Human_Use/13218879

الاتاحة: https://doi.org/10.1021/acs.jafc.0c05612.s001

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/figure/Clustering_and_cell_type_identification_of_cells_in_epididymal_and_inguinal_adipose_depots_/17710124

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.g001

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/figure/Differential_accessibility_of_peaks_with_transcription_factor_motifs_in_response_to_VSG_/17710130

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.g003

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/figure/Adipose_depot_specific_differences_in_cells_from_SHAM_surgery_mice_/17710127

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.g002

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/figure/Accessibility_changes_in_genes_after_VSG_in_inguinal_mature_adipocytes_/17710133

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.g004

المؤلفون: Blaine Harlan (11890751), Hui Gyu Park (7360718), Roman Spektor (237094), Bethany Cummings (11890754), J. Thomas Brenna (63512), Paul D. Soloway (51469)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Physiology, Immunology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vertical sleeve gastrectomy, term weight loss, received sham surgery, precede weight loss, fatty acid desaturase, dependent metabolic shift, cell atac sequencing, treat obesity resulting, specific cellular composition, chromatin accessibility patterns, cell chromatin accessibility, div >< p, epididymal adipose depots, epididymal depots, specific reduction, attenuate obesity, adipose plays, substantially reduced, reduced accumulation, observed depot, mechanisms underlying, mature adipocytes, lipid profiling

Relation: https://figshare.com/articles/figure/Reduced_accessibility_in_Scd1_leads_to_less_accumulation_of_unsaturated_fatty_acids_/17710139

الاتاحة: https://doi.org/10.1371/journal.pone.0261783.g005

المؤلفون: Dong Hao Wang (3188649), Hui Gyu Park (7360718), Zhen Wang (72451), R. J. Scott Lacombe (10893443), Vadim V. Shmanai (1754725), Andrei V. Bekish (1854985), Karsten Schmidt (9997), Mikhail S. Shchepinov (1854982), J. Thomas Brenna (63512)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Biotechnology, Developmental Biology, Plant Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, EPA, allylic D-HUFA production, methyl end deuterates, allylic position, D 9-11 DHA, allylic D isotopologues, bi, Sodiated PB D-HUFA result, isotopomer-specific D composition, Unsaturated Hydrocarbon Chains, CID, allylic positions, isotopologues D 5-7 linolenic acid, D 9-11 docosahexaenoic acid, ARA

Relation: https://figshare.com/articles/dataset/Toward_Quantitative_Sequencing_of_Deuteration_of_Unsaturated_Hydrocarbon_Chains_in_Fatty_Acids/14700179

الاتاحة: https://doi.org/10.1021/acs.analchem.1c01016.s002

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/figure/QQ_plots_for_Stage_1_1df_interaction_term_i_P_i_-values_and_2df_joint_test_i_P_i_-values_for_lipid_traits_/14293789

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s002

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/figure/Fish_oil_supplementation_taken_at_two_time_points_/14293792

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s003

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/figure/Manhattan_plots_for_Stage_1_1df_interaction_term_i_P_i_-values_and_2df_joint_test_i_P_i_-values_for_lipid_traits_/14293786

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s001

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/dataset/Participant_characteristics_/14293798

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s005

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/figure/Visualization_of_the_G_E_interaction_regression_model_/14293795

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s004

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/dataset/Numbers_of_stage_1_significant_variants_/14293801

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s006

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/figure/Overview_of_the_analysis_performed_in_this_study_/14293822

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.g001

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/dataset/Numbers_of_genome-wide_significance_loci_in_only_Stage_1_/14293807

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s008

المؤلفون: Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233)

مصطلحات موضوعية: Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C

Relation: https://figshare.com/articles/dataset/Numbers_of_replicated_variants_/14293804

الاتاحة: https://doi.org/10.1371/journal.pgen.1009431.s007