المؤلفون: Zhou Chen, Sandra Zakrzewska, Holly S. Hajare, J. Du Bois, Daniel L. Minor, Jr.

المصدر: STAR Protocols, Vol 5, Iss 1, Pp 102792- (2024)

مصطلحات موضوعية: Protein Biochemistry, Protein expression and purification, Structural Biology, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166723007591; https://doaj.org/toc/2666-1667

URL الوصول: https://doaj.org/article/31608f98045f4bf78d28744aa82a16b1

المؤلفون: Anna V. Elleman, Gabrielle Devienne, Christopher D. Makinson, Allison L. Haynes, John R. Huguenard, J. Du Bois

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/bf380589f814439eb42a94b2247df74e

المؤلفون: Anna V. Elleman, Gabrielle Devienne, Christopher D. Makinson, Allison L. Haynes, John R. Huguenard, J. Du Bois

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/449049f0a23341bca426eafa669d5b54

المؤلفون: Mengyuan Xu, Torben Neelands, Alexander S Powers, Yan Liu, Steven D Miller, Grigore D Pintilie, J Du Bois, Ron O Dror, Wah Chiu, Merritt Maduke

المصدر: eLife, Vol 12 (2024)

مصطلحات موضوعية: ion channel mechanisms, voltage-dependent gating, ion channel pharmacology, cryo-electron microscopy, electrophysiology, molecular dynamics simulations, Medicine, Science, Biology (General), QH301-705.5

Relation: https://elifesciences.org/articles/90648; https://doaj.org/toc/2050-084X; RP90648; https://doaj.org/article/ff8936247b544286b1d7a57aab5b1a3c

الاتاحة: https://doi.org/10.7554/eLife.90648
https://doaj.org/article/ff8936247b544286b1d7a57aab5b1a3c

المؤلفون: Jeremy D. Griffin (1534675), David B. Vogt (5931428), J. Du Bois (8173920), Matthew S. Sigman (1306671)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Evolutionary Biology, Inorganic Chemistry, Infectious Diseases, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, Mechanistic Guidance, site, dichloroacetic acid, methylene, Site-selectivity, Enhanced Site-Selectivity, Ruthenium, acid-stable, choice, functionalization, parameter, oxidation, bi, Electronic differences, Complexe, catalyst, correlates product selectivity outcomes, Catalyzed, product selectivity, electron-richnes, model

Relation: https://figshare.com/articles/journal_contribution/Mechanistic_Guidance_Leads_to_Enhanced_Site-Selectivity_in_C_H_Oxidation_Reactions_Catalyzed_by_Ruthenium_bis_Bipyridine_Complexes/15134802

الاتاحة: https://doi.org/10.1021/acscatal.1c02593.s001

المؤلفون: James B. C. Mack (4180939), John D. Gipson (2693029), J. Du Bois (8173920), Matthew S. Sigman (1306671)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Neuroscience, Pharmacology, Biotechnology, Evolutionary Biology, Sociology, Cancer, Infectious Diseases, Space Science, Chemical Sciences not elsewhere classified, Enable, Hydroxylation, Correction, Aqueou, Amine, Functionalization, Derivative, Ruthenium-Catalyzed

Relation: https://figshare.com/articles/journal_contribution/Correction_to_Ruthenium-Catalyzed_C_H_Hydroxylation_in_Aqueous_Acid_Enables_Selective_Functionalization_of_Amine_Derivatives_/13924004

الاتاحة: https://doi.org/10.1021/jacs.1c00564.s001

المؤلفون: Hassan Pajouhesh, Anton Delwig, Jacob T. Beckley, Sheri Klas, Dennis Monteleone, Xiang Zhou, George Luu, J. Du Bois, John C. Hunter, John V. Mulcahy

المصدر: ACS Medicinal Chemistry Letters. 13:1763-1768

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::102cff2de10cc253178902476de0b6ce
https://doi.org/10.1021/acsmedchemlett.2c00378

المؤلفون: Apurva A. Oak, Tifany Chu, Pattareeya Yottasan, Parth D. Chhetri, Jie Zhu, J. Du Bois, Onur Cil

المصدر: Molecular Pharmacology. 102:106-115

مصطلحات موضوعية: Pharmacology, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::091ca4eca9231b65c879a824b9281a4e
https://doi.org/10.1124/molpharm.122.000542

المؤلفون: Husniye Kantarci, Pablo D. Elvira, Arun P. Thottumkara, Manasi Iyer, Lauren J. Donovan, Micaela Quinn Dugan, Nicholas Ambiel, Emma M. O’Connell, Alejandro Granados, Hong Zeng, Nay L. Saw, Amanda Brosius Lutz, Steven A. Sloan, Erin E. Gray, Khanh V. Tran, Aditi Vichare, Ashley K. Yeh, Alexandra E. Münch, Max Huber, Aditi Agrawal, Maurizio Morri, Mehrdad Shamloo, Thomas Anthony Anderson, Vivianne L. Tawfik, J. Du Bois, J. Bradley Zuchero

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c649b8270dfe1ec4fc02b52106804825
https://doi.org/10.2139/ssrn.4405268

المؤلفون: Zhou Chen, Sandra Zakrzewska, Holly S. Hajare, Aurora Alvarez-Buylla, Fayal Abderemane-Ali, Maximiliana Bogan, Dave Ramirez, Lauren A. O’Connell, J. Du Bois, Daniel L. Minor

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 44

مصطلحات موضوعية: anuran, Multidisciplinary, Rana catesbeiana, saxiphilin, Neurotoxins, Biophysics, saxitoxin, toxin resistance, Ligands, Animals, Carrier Proteins, Guanidine, Saxitoxin

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025c106450d858e7d469c2c41b558667
https://pubmed.ncbi.nlm.nih.gov/36279441

المؤلفون: David B. Vogt, Matthew S. Sigman, Jeremy D. Griffin, J. Du Bois

المصدر: ACS Catalysis. 11:10479-10486

مصطلحات موضوعية: Bipyridine, chemistry.chemical_compound, Chemistry, Site selectivity, chemistry.chemical_element, General Chemistry, Combinatorial chemistry, Redox, Catalysis, Ruthenium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6adbfab416e672f3db05feedaf57b067
https://doi.org/10.1021/acscatal.1c02593

المؤلفون: Keri A. McKiernan, J. Du Bois, Yuri A. Kuryshev, Austin L. Reese, John R. Huguenard, Merritt Maduke, Xianlan Wen, Caiyun Wu, Anna K. Koster, Erin E. Gray

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Patch-Clamp Techniques, Central nervous system, Drug Evaluation, Preclinical, CHO Cells, Hippocampal formation, Hippocampus, Cell Line, Small Molecule Libraries, Structure-Activity Relationship, Cricetulus, Organ Culture Techniques, Chloride Channels, medicine, Extracellular, Animals, Humans, Receptor, Mice, Knockout, Binding Sites, Multidisciplinary, Dose-Response Relationship, Drug, urogenital system, Chemistry, Pyramidal Cells, Transporter, Biological Sciences, Cell biology, CLC-2 Chloride Channels, Mice, Inbred C57BL, Molecular Docking Simulation, Electrophysiology, medicine.anatomical_structure, Knockout mouse, Chloride channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f76bda7caae528ac1e2742ad4cab3c
https://doi.org/10.1073/pnas.2009977117

المؤلفون: James B. C. Mack, Matthew S. Sigman, Sophia G. Robinson, J. Du Bois, Sara N. Alektiar

المصدر: Organic Letters. 22:7060-7063

مصطلحات موضوعية: chemistry.chemical_element, Hydroxylation, 010402 general chemistry, Electrochemistry, 01 natural sciences, Biochemistry, Catalysis, Ruthenium, chemistry.chemical_compound, Polymer chemistry, Amines, Physical and Theoretical Chemistry, Amine derivatives, Aqueous solution, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Water, 0104 chemical sciences, chemistry, Solvents, Protons, Oxidation-Reduction, Hydrogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076108f456da6c1ea4f1dc4033fbd7db
https://doi.org/10.1021/acs.orglett.0c01313

المؤلفون: Anna V. Elleman, J. Du Bois

المصدر: Chembiochem

مصطلحات موضوعية: Nociception, Organic Chemistry, Molecular Medicine, Humans, Pain, Voltage-Gated Sodium Channels, Molecular Biology, Biochemistry, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8648802c64a3e22240bf5fc750fbbd
https://pubmed.ncbi.nlm.nih.gov/35315190

المؤلفون: Doris T. Y. Tang, Jeffrey E. Merit, T. Aaron Bedell, J. Du Bois

المصدر: J Org Chem

مصطلحات موضوعية: Biological Products, Organic Chemistry, Oxidation-Reduction, Article, Saxitoxin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5504141443e671df5280a6c3ab31e151
https://europepmc.org/articles/PMC8857915/

المؤلفون: Nicholas D. Chiappini, Kerry Betz, J. Du Bois

المصدر: Organic Letters. 22:1687-1691

مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Organic Chemistry, Intermolecular force, Alkyl bromide, Physical and Theoretical Chemistry, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Biochemistry, Medicinal chemistry, Amination, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43e390cbcced29a2584c59cd78ff9179
https://doi.org/10.1021/acs.orglett.9b04096

المؤلفون: Claire M. Colleran, Robert A. Craig, Catherine E. Garrison, Megan E. Kobiela, Zhou Chen, John P. Dumbacher, Lauren A. O’Connell, Fayal Abderemane-Ali, Daniel L. Minor, Nathan D. Rossen, J. Du Bois

المصدر: The Journal of general physiology, vol 153, iss 9
The Journal of General Physiology

مصطلحات موضوعية: Amphibian, Phyllobates, Molecular Pharmacology, Physiology, Medical Physiology, Biophysics, medicine.disease_cause, complex mixtures, Article, Poisons, Sodium Channels, Molecular Physiology, Birds, chemistry.chemical_compound, biology.animal, medicine, Animals, Batrachotoxins, Genetics, Saxitoxin, Mutation, biology, Toxin, Sodium channel, biology.organism_classification, chemistry, Pitohui, Batrachotoxin, Anura

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8851458c1711bcba644a3cefa40512
https://pubmed.ncbi.nlm.nih.gov/34491263

المؤلفون: Megan E. Kobiela, Nathan D. Rossen, Robert A. Craig, John P. Dumbacher, Catherine E. Garrison, Lauren A. O’Connell, J. Du Bois, Fayal Abderemane-Ali, Daniel L. Minor

مصطلحات موضوعية: Genetics, Phyllobates, Mutation, biology, Toxin, Sodium channel, Context (language use), biology.organism_classification, medicine.disease_cause, complex mixtures, chemistry.chemical_compound, chemistry, Pitohui, Toxin resistance, medicine, Batrachotoxin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17a82f7af96a94cb21e083854fcfc90f
https://doi.org/10.1101/2020.10.29.361212

المؤلفون: H. S. Hajare, Anton Delwig, Dennis Monteleone, G. Luu, J. Du Bois, Jacob T. Beckley, John Mulcahy, David C. Yeomans, Bryan D. Moyer, Joseph Ligutti, Xiang Zhou, S. Amagasu, Hassan Pajouhesh

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

مصطلحات موضوعية: Gene isoform, Multidisciplinary, Drug discovery, business.industry, Chemistry, Pain medicine, Sodium channel, lcsh:R, lcsh:Medicine, Pharmacology, Ligand (biochemistry), Small molecule, Article, Cell biology, medicine.anatomical_structure, Nociception, Dorsal root ganglion, NAV1, Extracellular, medicine, lcsh:Q, lcsh:Science, business, Receptor, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1b7580668f9d44787ac5084735fe50
https://doi.org/10.1038/s41598-020-71135-2

المؤلفون: James B. C. Mack, Matthew S. Sigman, J. Du Bois, Katherine L. Walker, Richard N. Zare, Robert M. Waymouth, Sophia G. Robinson

المصدر: Journal of the American Chemical Society. 141:972-980

مصطلحات موضوعية: Substituent, chemistry.chemical_element, General Chemistry, Electrochemistry, Biochemistry, Combinatorial chemistry, Catalysis, Dissociation (chemistry), Turnover number, Ruthenium, Hydroxylation, chemistry.chemical_compound, Bipyridine, Colloid and Surface Chemistry, chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8380bc40eda27a2712ea4d878be9301f
https://doi.org/10.1021/jacs.8b10950