المؤلفون: Izabella Góral, Tomasz Wichur, Emilia Sługocka, Justyna Godyń, Natalia Szałaj, Paula Zaręba, Monika Głuch-Lutwin, Barbara Mordyl, Dawid Panek, Anna Więckowska

المصدر: Molecules, Vol 29, Iss 11, p 2616 (2024)

مصطلحات موضوعية: GSK-3β, IKK-β, ROCK-1, anti-inflammatory activity, neuroprotective properties Alzheimer’s disease, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/11/2616; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/d794b4a155cb4c9da646e809bc8a5781

المؤلفون: Krzysztof Więckowski, Natalia Szałaj, Beata Gryzło, Tomasz Wichur, Izabella Góral, Emilia Sługocka, Joanna Sniecikowska, Gniewomir Latacz, Agata Siwek, Justyna Godyń, Adam Bucki, Marcin Kołaczkowski, Anna Więckowska

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9443

مصطلحات موضوعية: Alzheimer’s disease, cholinesterase inhibitors, AChE, BuChE, 5-HT 6 receptor ligands, antioxidant properties, metal-chelating properties, multifunctional ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms23169443

الاتاحة: https://doi.org/10.3390/ijms23169443

المؤلفون: Izabella Góral, Kamil Łątka, Marek Bajda

المصدر: Biomolecules; Volume 10; Issue 1; Pages: 102

مصطلحات موضوعية: norepinephrine transporter, homology modeling, ligand docking, reuptake inhibitors

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biomacromolecules: Proteins; https://dx.doi.org/10.3390/biom10010102

الاتاحة: https://doi.org/10.3390/biom10010102

المؤلفون: Krzysztof, Więckowski, Natalia, Szałaj, Beata, Gryzło, Tomasz, Wichur, Izabella, Góral, Emilia, Sługocka, Joanna, Sniecikowska, Gniewomir, Latacz, Agata, Siwek, Justyna, Godyń, Adam, Bucki, Marcin, Kołaczkowski, Anna, Więckowska

المصدر: International journal of molecular sciences. 23(16)

مصطلحات موضوعية: Serotonin, Structure-Activity Relationship, Amyloid beta-Peptides, Alzheimer Disease, Butyrylcholinesterase, Drug Design, Receptors, Serotonin, Acetylcholinesterase, Humans, Cholinesterase Inhibitors, Ligands, Antioxidants, Chelating Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6bd4358802443ef327e1978a76a7da5a
https://pubmed.ncbi.nlm.nih.gov/36012707

المؤلفون: Tomasz, Wichur, Anna, Pasieka, Justyna, Godyń, Dawid, Panek, Izabella, Góral, Gniewomir, Latacz, Ewelina, Honkisz-Orzechowska, Adam, Bucki, Agata, Siwek, Monika, Głuch-Lutwin, Damijan, Knez, Xavier, Brazzolotto, Stanislav, Gobec, Marcin, Kołaczkowski, Raimon, Sabate, Barbara, Malawska, Anna, Więckowska

المصدر: European journal of medicinal chemistry. 225

مصطلحات موضوعية: Amyloid beta-Peptides, Indoles, Dose-Response Relationship, Drug, Molecular Structure, tau Proteins, Hep G2 Cells, Ligands, Molecular Docking Simulation, Mice, Protein Aggregates, Structure-Activity Relationship, Butyrylcholinesterase, Receptors, Serotonin, Drug Discovery, Electrophorus, Acetylcholinesterase, Microsomes, Liver, Animals, Humans, Cholinesterase Inhibitors, Horses, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::077914f6dc7def7c5c689536d69bdbf6
https://pubmed.ncbi.nlm.nih.gov/34461507

المؤلفون: Tomasz, Wichur, Justyna, Godyń, Izabella, Góral, Gniewomir, Latacz, Adam, Bucki, Agata, Siwek, Monika, Głuch-Lutwin, Barbara, Mordyl, Joanna, Śniecikowska, Maria, Walczak, Damijan, Knez, Marko, Jukič, Kinga, Sałat, Stanislav, Gobec, Marcin, Kołaczkowski, Barbara, Malawska, Xavier, Brazzolotto, Anna, Więckowska

المصدر: European journal of medicinal chemistry. 225

مصطلحات موضوعية: Male, Models, Molecular, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, Cell Survival, Hep G2 Cells, Crystallography, X-Ray, Mice, Protein Aggregates, Structure-Activity Relationship, Neuroprotective Agents, Drug Development, Alzheimer Disease, Butyrylcholinesterase, Receptors, Serotonin, Electrophorus, Animals, Humans, Cholinesterase Inhibitors, Horses

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ee45fc25145a25e10b16d6f82c3ab957
https://pubmed.ncbi.nlm.nih.gov/34530376

المؤلفون: Dorota Stary, Marharyta Barbasevich, Jędrzej Kukułowicz, Izabella Góral, Marek Bajda, Hanna Baltrukevich, Justyna Godyń

مصطلحات موضوعية: chemistry.chemical_classification, Virtual screening, biology, Kinase, In silico, Organic Chemistry, Active site, Analytical Chemistry, Inorganic Chemistry, chemistry.chemical_compound, Enzyme, Biochemistry, chemistry, Ribose, biology.protein, Thymidine phosphorylase, Thymidine, Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd4540dc682851481ed93e8dee3b5c2
https://ruj.uj.edu.pl/xmlui/handle/item/283281

المؤلفون: Xavier Brazzolotto, Izabella Góral, Anna Pasieka, Gniewomir Latacz, Anna Więckowska, Adam Bucki, Dawid Panek, Barbara Malawska, Marcin Kołaczkowski, Tomasz Wichur, Raimon Sabaté, Damijan Knez, Monika Głuch-Lutwin, Justyna Godyń, Ewelina Honkisz-Orzechowska, Stanislav Gobec, Agata Siwek

المصدر: European Journal of Medicinal Chemistry. 225:113783

مصطلحات موضوعية: Pharmacology, Indole test, cholinesterase inhibitors, biology, CYP3A4, β-amyloid, Chemistry, Amyloid beta, Organic Chemistry, General Medicine, Alzheimer's disease, In vitro, Biochemistry, Tacrine, multifunctional agents, 5-HT6 antagonists, Drug Discovery, Tau protein, medicine, 5-HT6 receptor, biology.protein, Butyrylcholinesterase, medicine.drug, Cholinesterase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e6511bad0aaf428df90277374a636a
https://doi.org/10.1016/j.ejmech.2021.113783

المؤلفون: José Marco-Contelles, Mourad Chioua, Eva Ramos, Gniewomir Latacz, Izabella Góral, Águeda González-Rodríguez, Oscar M. Bautista-Aguilera, Víctor Farré Alins, Natalia Szałaj, Adam Bucki, Francisco López-Muñoz, Alejandro Romero, Anna Więckowska, Javier Egea, Katarzyna Kieć-Kononowicz

المساهمون: Instituto de Investigación Sanitaria Hospital Universitario de La Princesa (IIS-IP), Instituto Teófilo Hernando de I+D del Medicamento (ITH), Neurotransmisión y Neuroprotección Farmacológica Teófilo Hernando (BIO M-026)

المصدر: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
ACS Chemical Neuroscience

مصطلحات موضوعية: Physiology, Monoamine oxidase, Cognitive Neuroscience, In silico, Cytotoxicity, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Cytochrome P450 enzymes, ADME-tox, Viability assay, 030304 developmental biology, 0303 health sciences, ASS234, CYP3A4, Chemistry, PF9601N, Cell Biology, General Medicine, MAO inhibitors, Alzheimer's disease, Farmacia, In vitro, Contilisant, Multitarget directed ligands, Metabolism, Cell culture, Microsome, Alzheimer’s disease, 030217 neurology & neurosurgery, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa85a307aedfd9889b82ebe41f34bc9
https://ruj.uj.edu.pl/xmlui/handle/item/264594