المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

المصدر: PLoS ONE, Vol 18, Iss 11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686484/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/551c09fde19346b8adeeea88bf4b74d2

المؤلفون: Svetlana V. Baranova, Polina V. Zhdanova, Anastasia D. Koveshnikova, Pavel E. Pestryakov, Ivan P. Vokhtantsev, Alexander A. Chernonosov, Vladimir V. Koval

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 19, p 10862 (2024)

مصطلحات موضوعية: CRISPR/Cas systems, Cas9 activity, sgRNA, oligonucleotide mismatch, cleavage, thermodynamics, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/19/10862; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/ef2c4557c74b425cac2a86543e39cd27

الاتاحة: https://doi.org/10.3390/ijms251910862
https://doaj.org/article/ef2c4557c74b425cac2a86543e39cd27

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/PCR_protocol_for_genomic_targets_amplification_/24663180

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s002
https://figshare.com/articles/journal_contribution/PCR_protocol_for_genomic_targets_amplification_/24663180

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Oligonucleotides_used_in_this_study_/24663177

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s001
https://figshare.com/articles/journal_contribution/Oligonucleotides_used_in_this_study_/24663177

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Protection_of_Cas9-generated_dsDNA1_2_cleavage_product_from_degradation_in_cell_extracts_/24663210

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s009
https://figshare.com/articles/journal_contribution/Protection_of_Cas9-generated_dsDNA1_2_cleavage_product_from_degradation_in_cell_extracts_/24663210

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Cleavage_of_the_pMSH2_plasmid_substrate_by_Cas9_sgRNApMSH2_in_the_presence_of_different_proteins_/24663222

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s012
https://figshare.com/articles/journal_contribution/Cleavage_of_the_pMSH2_plasmid_substrate_by_Cas9_sgRNApMSH2_in_the_presence_of_different_proteins_/24663222

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Cleavage_of_the_oligonucleotide_substrate_by_Cas9_nickase_mutants_in_the_presence_of_PARP1_and_PARP2_/24663186

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s004
https://figshare.com/articles/journal_contribution/Cleavage_of_the_oligonucleotide_substrate_by_Cas9_nickase_mutants_in_the_presence_of_PARP1_and_PARP2_/24663186

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Cleavage_of_the_plasmid_substrate_by_Cas9_nickase_mutants_in_the_presence_of_PARP1_and_PARP2_/24663192

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s005
https://figshare.com/articles/journal_contribution/Cleavage_of_the_plasmid_substrate_by_Cas9_nickase_mutants_in_the_presence_of_PARP1_and_PARP2_/24663192

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Substrates_used_in_the_Cas9_activity_assays_/24663183

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s003
https://figshare.com/articles/journal_contribution/Substrates_used_in_the_Cas9_activity_assays_/24663183

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Binding_of_PARP1_and_PARP2_to_the_dsDNA_substrate_of_Cas9_/24663201

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s007
https://figshare.com/articles/journal_contribution/Binding_of_PARP1_and_PARP2_to_the_dsDNA_substrate_of_Cas9_/24663201

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Binding_of_Cas9_and_its_mutant_forms_to_the_dsDNA_substrate_of_Cas9_/24663195

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s006
https://figshare.com/articles/journal_contribution/Binding_of_Cas9_and_its_mutant_forms_to_the_dsDNA_substrate_of_Cas9_/24663195

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Binding_of_dCas9_sgRNA_complex_PARP1_and_PARP2_to_plasmid_DNA_/24663204

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s008
https://figshare.com/articles/journal_contribution/Binding_of_dCas9_sgRNA_complex_PARP1_and_PARP2_to_plasmid_DNA_/24663204

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Effects_of_DNA_ligase_I_on_the_nickase_activity_of_Cas9_/24663213

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s010
https://figshare.com/articles/journal_contribution/Effects_of_DNA_ligase_I_on_the_nickase_activity_of_Cas9_/24663213

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Binding_of_Ku70_80_RPA_and_YB1_to_the_dsDNA_substrate_of_Cas9_/24663219

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s011
https://figshare.com/articles/journal_contribution/Binding_of_Ku70_80_RPA_and_YB1_to_the_dsDNA_substrate_of_Cas9_/24663219

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Effects_of_YB1_on_the_cleavage_activity_of_Cas9_/24663228

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s013
https://figshare.com/articles/journal_contribution/Effects_of_YB1_on_the_cleavage_activity_of_Cas9_/24663228

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/journal_contribution/Original_gel_images_/24663237

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.s015
https://figshare.com/articles/journal_contribution/Original_gel_images_/24663237

المؤلفون: Natalia A. Torgasheva, Evgeniia A. Diatlova, Inga R. Grin, Anton V. Endutkin, Grigory V. Mechetin, Ivan P. Vokhtantsev, Anna V. Yudkina, Dmitry O. Zharkov

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7286

مصطلحات موضوعية: DNA repair, base excision repair, DNA glycosylases, noncatalytic protein domains, intrinsically disordered protein regions, protein–protein interactions, post-translational modifications, DNA binding, lesion search in DNA

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms23137286

الاتاحة: https://doi.org/10.3390/ijms23137286

المؤلفون: Anna V. Yudkina, Anton V. Endutkin, Eugenia A. Diatlova, Nina A. Moor, Ivan P. Vokhtantsev, Inga R. Grin, Dmitry O. Zharkov

المصدر: Genes; Volume 11; Issue 8; Pages: 866

مصطلحات موضوعية: DNA damage, DNA repair, tight protein–DNA complexes, DNA polymerases, facilitated diffusion, molecular traffic

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes11080866

الاتاحة: https://doi.org/10.3390/genes11080866

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/figure/Cas9_sgRNA_PARP1_and_PARP2_binding_to_DNA_/24663246

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.g002
https://figshare.com/articles/figure/Cas9_sgRNA_PARP1_and_PARP2_binding_to_DNA_/24663246

المؤلفون: Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Developmental Biology, Mental Health, Space Science, Astronomical and Space Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, dependent gene editing, streptococcus pyogenes <, dna damage signalling, dna break sensing, div >< p, enzyme mostly orthogonal, dsb sensor ), closest homolog poly, repair p, mostly orthogonal, target dna, cellulo <, repair due, strand breaks, proteins involved, polymerase 2, polymerase 1, natural regulation

Relation: https://figshare.com/articles/figure/Effects_of_RPA_on_the_Cas9_activity_/24663264

الاتاحة: https://doi.org/10.1371/journal.pone.0294683.g007
https://figshare.com/articles/figure/Effects_of_RPA_on_the_Cas9_activity_/24663264