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1Academic Journal
المؤلفون: Israel Ríos, Baltasar López-Navarro, Mónica Torres-Torresano, Blanca Soler Palacios, Miriam Simón-Fuentes, Ángeles Domínguez-Soto, Ittai B. Muller, Gerrit Jansen, Ángel L. Corbí, Amaya Puig-Kröger
المصدر: Journal of Innate Immunity, Pp 1-14 (2022)
مصطلحات موضوعية: methotrexate, macrophages, macrophage reprogramming, Medicine, Internal medicine, RC31-1245
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: I Gede Putu Supadmanaba, Giulia Mantini, Ornella Randazzo, Mjriam Capula, Ittai B. Muller, Stella Cascioferro, Patrizia Diana, Godefridus J. Peters, Elisa Giovannetti
المصدر: Epigenetics, Vol 17, Iss 4, Pp 381-404 (2022)
مصطلحات موضوعية: pdac, splicing deregulation, mirna, interaction, splicing modulation, Genetics, QH426-470
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Ittai B. Muller, Stijn Meijers, Peter Kampstra, Steven van Dijk, Michel van Elswijk, Marry Lin, Anna M. Wojtuszkiewicz, Gerrit Jansen, Robert de Jonge, Jacqueline Cloos
المصدر: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)
مصطلحات موضوعية: Alternative splicing, RNA-sequencing, Computational performance, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1471-2105
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4Academic Journal
المؤلفون: Helen R. Gosselt, Maxime M. A. Verhoeven, Maurits C. F. J. de Rotte, Saskia M. F. Pluijm, Ittai B. Muller, Gerrit Jansen, Janneke Tekstra, Maja Bulatović-Ćalasan, Sandra G. Heil, Floris P. J. G. Lafeber, Johanna M. W. Hazes, Robert de Jonge
المصدر: Rheumatology and Therapy, Vol 7, Iss 4, Pp 837-850 (2020)
مصطلحات موضوعية: Arthritis, Health care, Methotrexate, Outcome assessment, Rheumatoid, Therapeutics, Diseases of the musculoskeletal system, RC925-935
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Bárbara Alonso, Enrique Capa-Sardón, Ittai B. Muller, Gerrit Jansen, Amaya Puig-Kröger, Miguel A. Vega, Antonio Castrillo, Ángel L. Corbí
المصدر: Frontiers in Immunology, Vol 13 (2022)
مصطلحات موضوعية: innate immunity, macrophage, macrophage polarization, LXR, inflammation, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Sara Fuentelsaz-Romero, Celia Barrio-Alonso, Raquel García Campos, Mónica Torres Torresano, Ittai B. Muller, Ana Triguero-Martínez, Laura Nuño, Alejandro Villalba, Rosario García-Vicuña, Gerrit Jansen, María-Eugenia Miranda-Carús, Isidoro González-Álvaro, Amaya Puig-Kröger
المصدر: Frontiers in Immunology, Vol 12 (2021)
مصطلحات موضوعية: macrophages, methotrexate, pemetrexed, sCD14, predictor biomarker, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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7Academic Journal
المؤلفون: Ittai B. Muller, Marry Lin, Robert Jonge, Nico Will, Baltasar López-Navarro, Conny van der Laken, Eduard A. Struys, Cees B. M. Oudejans, Yehuda G. Assaraf, Jacqueline Cloos, Amaya Puig-Kröger, Gerrit Jansen
المصدر: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9641
مصطلحات موضوعية: methotrexate, macrophages, gene expression, alternative splicing, folate metabolism, folylpolyglutamate synthetase
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Molecular Immunology; https://dx.doi.org/10.3390/ijms24119641
الاتاحة: https://doi.org/10.3390/ijms24119641
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8Academic Journal
المؤلفون: Ittai B. Muller (9238061), Stijn Meijers (11032200), Peter Kampstra (11032203), Steven van Dijk (11032206), Michel van Elswijk (11032209), Marry Lin (11032212), Anna M. Wojtuszkiewicz (11032215), Gerrit Jansen (3526331), Robert de Jonge (4926013), Jacqueline Cloos (11032218)
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9Academic Journal
المؤلفون: Helen R. Gosselt, Ittai B. Muller, Gerrit Jansen, Michel van Weeghel, Frédéric M. Vaz, Johanna M. W. Hazes, Sandra G. Heil, Robert de Jonge
المصدر: Journal of Personalized Medicine; Volume 10; Issue 4; Pages: 271
مصطلحات موضوعية: methotrexate, rheumatoid arthritis, metabolomics, biomarkers, treatment response
وصف الملف: application/pdf
Relation: https://dx.doi.org/10.3390/jpm10040271
الاتاحة: https://doi.org/10.3390/jpm10040271
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10
المؤلفون: Renske CF Hebing, Marry Lin, Maja Bulatovic Calasan, Ittai B Muller, Sohaila Mahmoud, Sandra Heil, Eduard A Struys, Bart JF van den Bemt, Jos WR Twisk, Willem Lems, Michael T Nurmohamed, Gerrit Jansen, Robert de Jonge
المساهمون: Rheumatology, AII - Inflammatory diseases, Clinical chemistry, Epidemiology and Data Science, APH - Health Behaviors & Chronic Diseases, APH - Methodology, AMS - Musculoskeletal Health, AMS - Tissue Function & Regeneration, ACS - Atherosclerosis & ischemic syndromes, Amsterdam Gastroenterology Endocrinology Metabolism, Clinical Chemistry
المصدر: Hebing, R C, Lin, M, Bulatovic Calasan, M, Muller, I B, Mahmoud, S, Heil, S, Struys, E A, van den Bemt, B J, Twisk, J W, Lems, W, Nurmohamed, M T, Jansen, G & de Jonge, R 2022, ' Pharmacokinetics of oral and subcutaneous methotrexate in red and white blood cells in patients with early rheumatoid arthritis : the methotrexate monitoring trial ', Annals of the Rheumatic Diseases . https://doi.org/10.1136/ard-2022-223398
Annals of the Rheumatic Diseases. BMJ Publishing Group
Annals of the Rheumatic Diseases, 82(4):223398, 460-467. BMJ Publishing Groupمصطلحات موضوعية: Rheumatology, Immunology, Immunology and Allergy, General Biochemistry, Genetics and Molecular Biology
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11
المؤلفون: Anna Wojtuszkiewicz, Yehuda G. Assaraf, Ittai B. Muller, Gerrit Jansen, Robert de Jonge, Michael T. Nurmohamed, Marieke M. ter Wee, Jacqueline Cloos, M. Lin, Willem F. Lems
المساهمون: Clinical chemistry, Rheumatology, AII - Inflammatory diseases, AMS - Musculoskeletal Health, AMS - Tissue Function & Regeneration, Epidemiology and Data Science, VU University medical center, ACS - Atherosclerosis & ischemic syndromes, Hematology laboratory, AII - Infectious diseases, Amsterdam Gastroenterology Endocrinology Metabolism, APH - Methodology, APH - Societal Participation & Health
المصدر: Muller, I B, Lin, M, Lems, W F, ter Wee, M M, Wojtuszkiewicz, A, Nurmohamed, M T, Cloos, J, Assaraf, Y G, Jansen, G & de Jonge, R 2021, ' Association of altered folylpolyglutamate synthetase pre-mRNA splicing with methotrexate unresponsiveness in early rheumatoid arthritis ', Rheumatology (Oxford, England), vol. 60, no. 3, pp. 1273-1281 . https://doi.org/10.1093/rheumatology/keaa428, https://doi.org/10.1093/rheumatology/keaa428
Rheumatology (Oxford, England), 60(3), 1273-1281. Oxford University Press
Rheumatology (Oxford, England)مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, treat-to-target, medicine.medical_specialty, drug response, Cobra, MTX, Real-Time Polymerase Chain Reaction, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Internal medicine, Acute lymphocytic leukemia, medicine, Humans, Pharmacology (medical), Treatment Failure, Peptide Synthases, Polyglutamylation, AcademicSubjects/MED00360, computer.programming_language, 030203 arthritis & rheumatology, business.industry, Folylpolyglutamate synthase, Intron, Genetic Variation, Clinical Science, Middle Aged, medicine.disease, Introns, Alternative Splicing, Methotrexate, 030104 developmental biology, Antirheumatic Agents, Rheumatoid arthritis, RNA splicing, Female, business, RA, disease activity, computer, medicine.drug
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12
المؤلفون: Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Bárbara Alonso, Enrique Capa-Sardón, Ittai B. Muller, Gerrit Jansen, Amaya Puig-Kröger, Miguel A. Vega, Antonio Castrillo, Ángel L. Corbí
مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, macrophage, macrophage polarization, LXR, inflammation
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13
المؤلفون: E.A. Struys, Renske C. F. Hebing, Ittai B. Muller, Gerrit Jansen, Willem F. Lems, Jacqueline Cloos, Conny J. van der Laken, Robert de Jonge, Paniz Heydari, Marry Lin, Michael T. Nurmohamed
المساهمون: Clinical chemistry, Medical oncology, AGEM - Endocrinology, metabolism and nutrition, AGEM - Inborn errors of metabolism, Rheumatology, ACS - Atherosclerosis & ischemic syndromes, AII - Inflammatory diseases, Amsterdam Movement Sciences - Rehabilitation & Development, Amsterdam Movement Sciences - Restoration and Development, CCA - Cancer biology and immunology, CCA - Cancer Treatment and quality of life, Hematology laboratory, CCA - Imaging and biomarkers
المصدر: Muller, I B, Lin, M, Struys, E A, Heydari, P, Hebing, R C F, Nurmohamed, M T, van der Laken, C, Lems, W F, Cloos, J, Jansen, G & de Jonge, R 2019, ' Development and validation of a sensitive UHPLC-MS/MS-based method for the analysis of folylpolyglutamate synthetase enzymatic activity in peripheral blood mononuclear cells : application in rheumatoid arthritis and leukemia patients ', Therapeutic Drug Monitoring, vol. 41, no. 5, pp. 598-606 . https://doi.org/10.1097/FTD.0000000000000638
Therapeutic Drug Monitoring, 41(5), 598-606. Lippincott Williams and Wilkinsمصطلحات موضوعية: musculoskeletal diseases, Drug, media_common.quotation_subject, Arthritis, Pharmacology, 030226 pharmacology & pharmacy, Peripheral blood mononuclear cell, Sensitivity and Specificity, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Tandem Mass Spectrometry, Cell Line, Tumor, medicine, Humans, Pharmacology (medical), Peptide Synthases, skin and connective tissue diseases, Chromatography, High Pressure Liquid, media_common, chemistry.chemical_classification, business.industry, Reproducibility of Results, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Leukemia, Enzyme, Methotrexate, chemistry, Cell culture, Rheumatoid arthritis, Leukocytes, Mononuclear, business, medicine.drug
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14
المؤلفون: Sara Fuentelsaz-Romero (10152872), Celia Barrio-Alonso (11652391), Raquel García Campos (11652394), Mónica Torres Torresano (11652397), Ittai B. Muller (9238061), Ana Triguero-Martínez (9031106), Laura Nuño (310348), Alejandro Villalba (627499), Rosario García-Vicuña (190000), Gerrit Jansen (3526331), María-Eugenia Miranda-Carús (312518), Isidoro González-Álvaro (118679), Amaya Puig-Kröger (312516)
مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, macrophages, methotrexate, pemetrexed, sCD14, predictor biomarker
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15
المؤلفون: Michal Stark, Elisa Giovannetti, Gerrit Jansen, Larry H. Matherly, Maria Gemelli, Godefridus J. Peters, Erik Thunnissen, Ittai B. Muller, Zhanjun Hou, P. A. Zucali, E. A. Struys, Niccola Funel, M. Perrino, Yehuda G. Assaraf
المساهمون: Medical oncology laboratory, CCA - Cancer biology and immunology, Pathology, Clinical chemistry, AGEM - Inborn errors of metabolism, AGEM - Endocrinology, metabolism and nutrition, Rheumatology, AGEM - Digestive immunity
المصدر: Annals of Oncology, 28(11), 2725-2732. Oxford University Press
Giovannetti, E, Zucali, P A, Assaraf, Y G, Funel, N, Gemelli, M, Stark, M, Thunnissen, E, Hou, Z, Muller, I B, Struys, E A, Perrino, M, Jansen, G, Matherly, L H & Peters, G J 2017, ' Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma : Clinical evidence and new pharmacological tools ', Annals of Oncology, vol. 28, no. 11, pp. 2725-2732 . https://doi.org/10.1093/annonc/mdx499مصطلحات موضوعية: Male, Mesothelioma, 0301 basic medicine, Oncology, Thymidylate synthase, Immunoenzyme Techniques, Reduced Folate Carrier Protein, chemistry.chemical_compound, 0302 clinical medicine, Tumor Cells, Cultured, Aged, 80 and over, biology, Hematology, Methylation, Middle Aged, Prognosis, Survival Rate, Pemetrexed, 030220 oncology & carcinogenesis, Antifolate, Immunohistochemistry, Female, Proton-Coupled Folate Transporter, medicine.drug, Adult, medicine.medical_specialty, Pleural Neoplasms, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, Gene silencing, Survival rate, Aged, Cell Proliferation, business.industry, Original Articles, Thymidylate Synthase, medicine.disease, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, biology.protein, Folic Acid Antagonists, business, Follow-Up Studies
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16
المصدر: Muller, I B, De Langen, A J, Giovannetti, E & Peters, G J 2017, ' Anaplastic lymphoma kinase inhibition in metastatic non-small cell lung cancer : Clinical impact of alectinib ', OncoTargets and Therapy, vol. 10, pp. 4535-4541 . https://doi.org/10.2147/OTT.S109493
OncoTargets and therapyمصطلحات موضوعية: 0301 basic medicine, Alectinib, Oncology, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Review, medicine.disease_cause, Tyrosine-kinase inhibitor, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, tyrosine kinase inhibitors, Medicine, Anaplastic lymphoma kinase, alectinib, Pharmacology (medical), Lung cancer, non-small cell lung cancer, crizotinib, Chemotherapy, Crizotinib, business.industry, acquired resistance, anaplastic lymphoma kinase, medicine.disease, ALK inhibitor, 030104 developmental biology, 030220 oncology & carcinogenesis, business, Carcinogenesis, medicine.drug
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17
المؤلفون: Gerrit Jansen, M. Lin, Jacqueline Cloos, Ittai B Muller, Willem F. Lems, Robert de Jonge, Yehuda G. Assaraf, Marieke M. ter Wee
المساهمون: Clinical chemistry, Medical oncology, Rheumatology, Amsterdam Movement Sciences - Rehabilitation & Development, Amsterdam Movement Sciences - Restoration and Development, AII - Inflammatory diseases, Epidemiology and Data Science, Hematology laboratory, AGEM - Endocrinology, metabolism and nutrition, AII - Infectious diseases
المصدر: Muller, I, Lin, M, Lems, W, Wee, M T, Cloos, J, Assaraf, Y, Jansen, G & Jonge, R D 2019, ' THU0063 PRE-MRNA SPLICING ALTERATIONS IN FOLYLPOLYGLUTAMATE SYNTHETASE IN BLOOD CELLS OF EARLY RHEUMATOID ARTHRITIS PATIENTS ARE ASSOCIATED WITH UNRESPONSIVENESS TO METHOTREXATE ' . https://doi.org/10.1136/annrheumdis-2019-eular.3215
مصطلحات موضوعية: medicine.medical_specialty, Arc (protein), business.industry, Cobra, medicine.disease, Gastroenterology, Folinic acid, Real-time polymerase chain reaction, Internal medicine, Rheumatoid arthritis, Toxicity, medicine, Methotrexate, business, computer, medicine.drug, computer.programming_language, Whole blood
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18
المؤلفون: Godefridus J. Peters, Richard J. Honeywell, Elisa Giovannetti, Ittai B. Muller, Adrianus J. de Langen
المساهمون: Medical oncology, Pulmonary medicine, CCA - Clinical Therapy Development, Medical oncology laboratory
المصدر: Muller, I B, De Langen, A J, Honeywell, R J, Giovannetti, E & Peters, G J 2016, ' Overcoming crizotinib resistance in ALK-rearranged NSCLC with the second-generation ALK-inhibitor ceritinib ', Expert Review of Anticancer Therapy, vol. 16, no. 2, pp. 147-157 . https://doi.org/10.1586/14737140.2016.1131612
Expert Review of Anticancer Therapy, 16(2), 147-157. Taylor and Francis Ltd.مصطلحات موضوعية: 0301 basic medicine, Alectinib, Lung Neoplasms, Brigatinib, Pyridines, medicine.drug_class, medicine.medical_treatment, Antineoplastic Agents, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Crizotinib, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Animals, Humans, Anaplastic lymphoma kinase, Medicine, Anaplastic Lymphoma Kinase, Pharmacology (medical), Sulfones, Protein Kinase Inhibitors, Chemotherapy, Ceritinib, business.industry, Receptor Protein-Tyrosine Kinases, ALK inhibitor, Pyrimidines, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, Tumor progression, 030220 oncology & carcinogenesis, Mutation, Cancer research, Pyrazoles, business, medicine.drug
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19
المؤلفون: Godefridus J. Peters, Elisa Giovannetti, Ittai B. Muller
المساهمون: CCA - Cancer biology and immunology, AGEM - Digestive immunity, Medical oncology laboratory, Clinical chemistry, AGEM - Re-generation and cancer of the digestive system
المصدر: Translational Cancer Research, 6, S1010-S1013. Society for Translational Medicine (STM)
Peters, G J, Muller, I B & Giovannetti, E 2017, ' Should alectinib or ceritinib be given as first line therapy for ALK positive non-small cell lung cancer patients instead of crizotinib? ', Translational Cancer Research, vol. 6, pp. S1010-S1013 . https://doi.org/10.21037/tcr.2017.06.54مصطلحات موضوعية: 0301 basic medicine, Oncology, Alectinib, Cancer Research, medicine.medical_specialty, Brigatinib, medicine.drug_class, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, medicine, Anaplastic lymphoma kinase, Radiology, Nuclear Medicine and imaging, Intensive care medicine, Lung cancer, Crizotinib, Ceritinib, business.industry, medicine.disease, Lorlatinib, ALK inhibitor, 030104 developmental biology, 030220 oncology & carcinogenesis, business, medicine.drug