المؤلفون: István Ledneczki, Pál Tapolcsányi, Eszter Gábor, János Éles, Júlia Barabás, Zoltán Béni, Balázs Varga, Ottilia Balázs, Viktor Román, László Fodor, Judit Szikra, Mónika Vastag, György Lévay, Éva Schmidt, Balázs Lendvai, István Greiner, Béla Kiss, Zsolt Némethy, Sándor Mahó

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vitro functional tests, r activity together, predict binding modes, molecular docking studies, inverse agonist property, inverse agonist features, based sar considerations, inverse agonists steroid, vivo dipsogenia test, rat liver microsomes, hts hit molecules, based histamine h, 3 , novel steroid, vivo potency, vivo h, special emphasis, receptor antagonists, place recognition, considerably stable

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Novel_Steroid-Based_Histamine_H_sub_3_sub_Receptor_Antagonists_Inverse_Agonists/25276448

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c02117.s002
https://figshare.com/articles/journal_contribution/Discovery_of_Novel_Steroid-Based_Histamine_H_sub_3_sub_Receptor_Antagonists_Inverse_Agonists/25276448

المؤلفون: Zsolt, Némethy, Béla, Kiss, Natasha, Lethbridge, Paul, Chazot, Tünde, Hajnik, Attila, Tóth, László, Détári, Éva, Schmidt, András, Czurkó, Diána, Kostyalik, Vilmos, Oláh, István, Hernádi, Ottilia, Balázs, E Sylvester, Vizi, István, Ledneczki, Sándor, Mahó, Viktor, Román, Balázs, Lendvai, György, Lévay

المصدر: European journal of pharmacology. 916

مصطلحات موضوعية: Histamine Agonists, Cognition, Guanosine 5'-O-(3-Thiotriphosphate), Animals, Receptors, Histamine H3, Histamine, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d00db9c21eae4a299c02b5487aa1036b
https://pubmed.ncbi.nlm.nih.gov/34965389

المؤلفون: Zsolt Némethy, Béla Kiss, Natasha Lethbridge, Paul Chazot, Tünde Hajnik, Attila Tóth, László Détári, Éva Schmidt, András Czurkó, Diána Kostyalik, Vilmos Oláh, István Hernádi, Ottilia Balázs, E. Sylvester Vizi, István Ledneczki, Sándor Mahó, Viktor Román, Balázs Lendvai, György Lévay

المصدر: European Journal of Pharmacology. 916:174621

مصطلحات موضوعية: Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1beae2435563c1ece7c1fadf0cc0b9b3
https://doi.org/10.1016/j.ejphar.2021.174621

المؤلفون: Zsolt Némethy, Balázs Lendvai, Balázs Krámos, Katalin Dudás Molnár, Ottilia Balázs, Anita Horváth, Áron Szigetvári, György Lévay, János Kóti, János Éles, Istvan Vago, István Ledneczki, András Visegrády, Mónika Vastag, Marta Than, Pál Tapolcsányi, Diána Kostyalik, Sándor Mahó, Sándor Kolok, Patrik Holm, László Fodor, István Greiner, László Kiss

المصدر: European Journal of Medicinal Chemistry. 222:113560

مصطلحات موضوعية: Male, alpha7 Nicotinic Acetylcholine Receptor, High-throughput screening, Allosteric regulation, Computational biology, Structure-Activity Relationship, chemistry.chemical_compound, Allosteric Regulation, α7 nicotinic acetylcholine receptor, Drug Discovery, Animals, Humans, Structure–activity relationship, Rats, Wistar, Novel object recognition, Binding site, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Oxalic Acid, Organic Chemistry, General Medicine, Amides, High-Throughput Screening Assays, Rats, Docking (molecular), Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25756ef61e702aa21bdd1b8a5b62e5bf
https://doi.org/10.1016/j.ejmech.2021.113560

المؤلفون: Viktor Román, Pál Tapolcsányi, György Lévay, István Greiner, István Ledneczki, János Éles, Rita Kedves, Sándor Mahó, Eszter Gábor, Ottilia Balázs, Eva Schmidt, Zsolt Némethy

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4525-4530

مصطلحات موضوعية: 0301 basic medicine, Chemistry, medicine.medical_treatment, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro, Steroid, 03 medical and health sciences, Histamine receptor, 030104 developmental biology, In vivo, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Molecular Medicine, Inverse agonist, Histamine H3 receptor, Molecular Biology, Binding affinities

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a8bdc6b2dbb983ae0f39a39b3fd260e
https://doi.org/10.1016/j.bmcl.2017.08.060

المؤلفون: István, Ledneczki, Zsolt, Némethy, Pál, Tapolcsányi, János, Éles, István, Greiner, Eszter, Gábor, Balázs, Varga, Ottilia, Balázs, Viktor, Román, György, Lévay, Sándor, Mahó

المصدر: Bioorganicmedicinal chemistry letters. 29(20)

مصطلحات موضوعية: Male, Molecular Structure, Solubility, Histamine Antagonists, Animals, Humans, Receptors, Histamine H3, Steroids, Rats, Wistar, Amides, Receptors, Muscarinic, Muscle Contraction, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6f06502bad9ee854fbc29e3e4e010a5f
https://pubmed.ncbi.nlm.nih.gov/31492518

المؤلفون: Balázs Lendvai, Anna E. Káncz, Pál Tapolcsányi, Zoltán Béni, János Kóti, Marta Than, Éva Bozó, János Éles, István Greiner, Judit Laszy, Zsolt Némethy, Sándor Mahó, András Visegrády, Márton Vass, Gyula Bugovits, György Lévay, István Ledneczki, Anikó Pocsai, Balázs Krámos, Ágota Szájli, Mónika Vastag, Patrik Holm, Sándor Kolok, Eszter Gábor, Ottilia Balázs, Anita Horváth, József Nagy

المصدر: European Journal of Medicinal Chemistry. 214:113189

مصطلحات موضوعية: Male, alpha7 Nicotinic Acetylcholine Receptor, Scopolamine, Allosteric regulation, Administration, Oral, Computational biology, Scaffold hopping, 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, Allosteric Regulation, α7 nicotinic acetylcholine receptor, Drug Discovery, Animals, Humans, Structure–activity relationship, Nicotinic Agonists, Homology modeling, Rats, Wistar, Maze Learning, Receptor, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Rodent model, General Medicine, Rats, 0104 chemical sciences, HEK293 Cells, Nicotinic agonist, Microsomes, Liver, Pyrazoles, Amnesia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ad9ffda37f8a3d089c88187d8a3c0f
https://doi.org/10.1016/j.ejmech.2021.113189

المؤلفون: Eszter Gábor, Ottilia Balázs, Viktor Román, Pál Tapolcsányi, Zsolt Némethy, Sándor Mahó, István Greiner, János Éles, István Ledneczki, Balázs Varga, György Lévay

المصدر: Bioorganic & Medicinal Chemistry Letters. 29:126643

مصطلحات موضوعية: 010405 organic chemistry, medicine.drug_class, Chemistry, medicine.medical_treatment, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Pharmacology, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, Steroid, 010404 medicinal & biomolecular chemistry, In vivo, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Molecular Medicine, Inverse agonist, Histamine H3 receptor, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::46d39b1f94d035dec83076c38d8b8bf5
https://doi.org/10.1016/j.bmcl.2019.126643

المؤلفون: George A. Olah, G. K. Surya Prakash, István Ledneczki, Sujith Chacko, Shashank Ravi

المصدر: Journal of Fluorine Chemistry. 129:1036-1040

مصطلحات موضوعية: Inorganic Chemistry, chemistry.chemical_compound, Chemistry, Yield (chemistry), Organic Chemistry, Environmental Chemistry, Organic chemistry, Halogenation, Stereoselectivity, Physical and Theoretical Chemistry, Biochemistry, Methane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::030353a620208d5a24c00eeae10f82db
https://doi.org/10.1016/j.jfluchem.2008.04.013

المؤلفون: István Ledneczki, Árpád Molnár, Peter Forgo

المصدر: Catalysis Letters. 119:296-303

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, General Chemistry, Alkylation, Anisole, Toluene, Catalysis, chemistry.chemical_compound, Hydrocarbon, Organic chemistry, Superacid, Benzene, Triflic acid, Naphthalene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::60a9b7bbf1b543e951f51ad7ba96e686
https://doi.org/10.1007/s10562-007-9234-2

المؤلفون: István Pálinkó, István Ledneczki, Annamária Molnár, János Kiss, Peter Forgo

المصدر: Journal of Molecular Structure. :349-354

مصطلحات موضوعية: Quantitative Biology::Biomolecules, Nuclear Theory, Organic Chemistry, Ab initio, Force field (chemistry), Analytical Chemistry, Inorganic Chemistry, chemistry.chemical_compound, chemistry, Computational chemistry, Amide, Physics::Atomic and Molecular Clusters, Physics::Atomic Physics, Physics::Chemical Physics, Conformational isomerism, Spectroscopy, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dfd0a1b506601854cc09d92a7c0558a8
https://doi.org/10.1016/j.molstruc.2006.11.017

المؤلفون: István Ledneczki, Mária Darányi, Ferenc Fülöp, Árpád Molnár

المصدر: Catalysis Today. 100:437-440

مصطلحات موضوعية: inorganic chemicals, chemistry.chemical_classification, organic chemicals, Catalyst support, General Chemistry, Solid acid, Heterogeneous catalysis, Aldehyde, Catalysis, chemistry.chemical_compound, chemistry, Nafion, Organic chemistry, heterocyclic compounds, Organic synthesis, Superacid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2ec0f7bc3045f75b9908379bf96cbd67
https://doi.org/10.1016/j.cattod.2004.09.076

المؤلفون: István Ledneczki, Árpád Molnár

المصدر: Synthetic Communications. 34:3683-3690

مصطلحات موضوعية: chemistry.chemical_compound, Chemical engineering, chemistry, Nafion, Organic Chemistry, food and beverages, Organic chemistry, General Medicine, Silica nanocomposite, Solid acid, Superacid, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5881e804cde31801edd541bc7ed7b74
https://doi.org/10.1081/scc-200032419

المؤلفون: Mihály Bartók, István Ledneczki, Imre Bucsi, Árpád Molnár

المصدر: Catalysis Letters. 89:1-9

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Styrene oxide, Organic chemistry, Reactivity (chemistry), Ether, General Chemistry, Tetralin, Alkylation, Friedel–Crafts reaction, Triflic acid, Catalysis, Cyclohexene oxide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aba578c0ec89d6925fe8919b7fc2d2d2
https://doi.org/10.1023/a:1024865322544

المؤلفون: George A. Olah, G. K. Surya Prakash, István Ledneczki, Sujith Chacko, Shashank Ravi

المصدر: ChemInform. 40

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Yield (chemistry), Halogenation, Stereoselectivity, General Medicine, Medicinal chemistry, Methane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f564c63b905a6c136b03abdb99dd868
https://doi.org/10.1002/chin.200907088

المؤلفون: István Ledneczki, Árpád Molnár, Pal M. Agocs

المصدر: ChemInform. 35

مصطلحات موضوعية: Chemistry, Organic chemistry, General Medicine, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6d74be95e9e34339600db116d3e7dfe8
https://doi.org/10.1002/chin.200411087

المؤلفون: István Ledneczki, Zsolt Némethy, Katalin Dudásné Molnár, Pál Tapolcsányi, Viktor Ilkei, István Vágó, Sándor Kolok, Márta Thán, Judit Laszy, Ottilia Balázs, Balázs Krámos, Áron Szigetvári, Imre Bata, Attila Makó, András Visegrády, László Fodor, Mónika Vastag, György Lévay, Balázs Lendvai, István Greiner, János Éles

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Biotechnology, Sociology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, α7 nachrs appears, suboptimal metabolic stability, preclinical development candidate, induced amnesia test, improved metabolic stability, low kinetic solubility, 53 , kinetic solubility, vivo <, vitro <, viable approach, thorough modifications, promising results, positive modulation, pharmacological profile, new chemotype, lead series, high level, cognitive enhancement, balanced physicochemical, azetidinespirochromone family, also carried

Relation: https://figshare.com/articles/journal_contribution/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602871

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01635.s002
https://figshare.com/articles/journal_contribution/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602871

المؤلفون: István Ledneczki

المصدر: Synlett; 11/6/2003, Vol. 2003 Issue 14, p2255-2257, 3p

المؤلفون: Árpád Molnár, István Ledneczki, Pal M. Agocs

المصدر: Scopus-Elsevier

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Nafion, Yield (chemistry), fungi, Organic Chemistry, food and beverages, Organic chemistry, Silica nanocomposite, Carbocation, Brønsted–Lowry acid–base theory, Methanesulfonic acid, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c0ee5cbeb9bb8620296dd29d25a119
http://www.scopus.com/inward/record.url?eid=2-s2.0-0242408190&partnerID=MN8TOARS