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المؤلفون: Bihua Li, Liesbeth van Emst, Isabel J. Latorre, Leo A. B. Joosten, Heather A. Kang, Vasiliki Matzaraki, Ramnik J. Xavier, Mihai G. Netea, Lingjia Kong, Simone J.C.F.M. Moorlag, Ariel Lefkovith, Martin Jaeger
المصدر: Cell Reports, 37, 7
Cell Rep
Cell Reports, 37
Cell Reports, Vol 37, Iss 7, Pp 110028-(2021)مصطلحات موضوعية: Male, Lipopolysaccharide, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Gene Expression, Systemic inflammation, Monocytes, trained immunity, chemistry.chemical_compound, 0302 clinical medicine, Biology (General), 0303 health sciences, Vaccination, Healthy Volunteers, 3. Good health, BCG vaccination, BCG Vaccine, Cytokines, Female, Inflammation Mediators, medicine.symptom, Adult, QH301-705.5, humanin, Heterologous, CCL3, single-cell sequencing, Biology, complex mixtures, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Immune system, Immunity, medicine, Humans, 030304 developmental biology, Humanin, Inflammation, Gene Expression Profiling, Immunity, Innate, Gene Expression Regulation, chemistry, Immunology, Transcriptome, Immunologic Memory, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52719b08df3cad238ea049c041e500c2
https://doi.org/10.1016/j .celrep.2021.110028 -
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المؤلفون: Casey T. Weaver, Charles O. Elson, Hein M. Tun, Henrietta Turner, James J. Moon, Trenton R. Schoeb, Raivo Kolde, Stacey N. Harbour, Qing Zhao, Isabel J. Latorre, Ehsan Khafipour, Ramnik J. Xavier
المصدر: The Journal of Immunology. 199:312-322
مصطلحات موضوعية: 0301 basic medicine, Cholera Toxin, Segmented filamentous bacteria, Immunology, Population, Inflammation, Biology, medicine.disease_cause, Inflammatory bowel disease, Article, Microbiology, Transcriptome, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Vancomycin, Intestine, Small, medicine, Animals, Germ-Free Life, Homeostasis, Immunology and Allergy, Intestinal Mucosa, education, education.field_of_study, Gene Expression Profiling, Cholera toxin, IgA Deficiency, Inflammatory Bowel Diseases, medicine.disease, Small intestine, Gastrointestinal Microbiome, Immunoglobulin A, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Th17 Cells, medicine.symptom, 030215 immunology
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المؤلفون: Andrew C. Tolonen, Mukund Varma, Isabel J. Latorre, Kara L. Conway, Betsabeh Khoramian Tusi, Aylwin Ng, Ariel Lefkovith, Bernard Khor, Vishnu Mohanan, Motohiko Kadoki, Daniel B. Graham, Kevin Gao, Ramnik J. Xavier
المصدر: J Immunol
مصطلحات موضوعية: Risk, Transcriptional Activation, Cell type, Genotype, T-Lymphocytes, Immunology, Autophagy-Related Proteins, Steroid biosynthesis, Biology, Article, Mice, Immune system, Crohn Disease, Genetic variation, Immunology and Allergy, Animals, Humans, Genetic Predisposition to Disease, Gene, ATG16L1, Cells, Cultured, Genetic association, Genetics, Mice, Knockout, Polymorphism, Genetic, Dendritic Cells, Mice, Inbred C57BL, Phenotype, Organ Specificity
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المؤلفون: Tarjei S. Mikkelsen, Daniel J. O’Connell, Matthew Sooknah, Daniel B. Graham, Thomas B. Sundberg, Raivo Kolde, Isabel J. Latorre, Ramnik J. Xavier
المصدر: Cell Systems. 2:323-334
مصطلحات موضوعية: 0301 basic medicine, Histology, Pathology and Forensic Medicine, Transcriptome, 03 medical and health sciences, Gene expression, STAT1, Transcription factor, Genetics, Regulation of gene expression, Reporter gene, Base Sequence, biology, Sequence Analysis, RNA, Gene Expression Profiling, NF-kappa B, High-Throughput Nucleotide Sequencing, Cell Biology, Cell biology, Gene expression profiling, 030104 developmental biology, Gene Expression Regulation, biology.protein, RNA, Signal transduction
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المؤلفون: Alykhan F. Shamji, Ramnik J. Xavier, Gautam Goel, Szu Yu Kuo, Adam B. Castoreno, Jaime H. Cheah, Petric Kuballa, Matthew G. Rees, Stuart L. Schreiber, Isabel J. Latorre, Leslie N. Aldrich, Brinton Seashore-Ludlow
المصدر: Journal of the American Chemical Society
مصطلحات موضوعية: Cell physiology, Vacuolar Proton-Translocating ATPases, Mannose 6-phosphate receptor, Cell Survival, Chemistry, Small Molecule Libraries, General Chemistry, Biochemistry, Small molecule, Article, Catalysis, Colloid and Surface Chemistry, medicine.anatomical_structure, Cell Line, Tumor, Lysosome, Organelle, medicine, Humans, V-ATPase, Macrolides, Enzyme Inhibitors, Lysosomes, Function (biology)
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المؤلفون: Liv Johannessen, Andrew J. Phillips, Isabel J. Latorre, Thomas B. Sundberg, Alykhan F. Shamji, Nathanael S. Gray, James Berstler, José Carlos Rodríguez Pérez, Raivo Kolde, Ramnik J. Xavier, Daniel B. Graham, Caitlin N. Russell, Stuart L. Schreiber, Brinton Seashore-Ludlow, Anne Fassl, Bernard Khor, Katelyn J Billings, Daniel J. O’Connell, Piotr Sicinski, Baishan Jiang
مصطلحات موضوعية: 0301 basic medicine, Phenotypic screening, medicine.medical_treatment, Regulator, Inflammation, Biology, Article, Small Molecule Libraries, 03 medical and health sciences, Mice, Structure-Activity Relationship, medicine, Animals, Humans, Myeloid Cells, Molecular Biology, Cells, Cultured, Innate immune system, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Cell Biology, Cyclin-Dependent Kinase 8, Cell biology, Interleukin-10, Mice, Inbred C57BL, Interleukin 10, 030104 developmental biology, Cytokine, medicine.symptom, Chemical genetics
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المؤلفون: Andrew J. Phillips, Adam Petrone, Daniel B. Graham, Alykhan F. Shamji, Huixian Wu, Thomas B. Sundberg, Stuart L. Schreiber, Isabel J. Latorre, Taebo Sim, Hwan Geun Choi, Ramnik J. Xavier, Nam Doo Kim, José Carlos Rodríguez Pérez, Bernard Khor, Liv Johannessen, Nathanael S. Gray, Yanke Liang
المصدر: ACS chemical biology. 11(8)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Biology, Pharmacology, Protein Serine-Threonine Kinases, Biochemistry, Article, 03 medical and health sciences, Inhibitory Concentration 50, Mice, In vivo, medicine, Animals, Phosphorylation, IC50, Protein Kinase Inhibitors, Cells, Cultured, Mice, Knockout, Innate immune system, Kinase, General Medicine, 030104 developmental biology, Cytokine, Molecular Probes, Knockout mouse, Molecular Medicine, Function (biology)
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المؤلفون: Laurel A. Monticelli, Jesper B. Moeller, Frederike Schmitz, Melanie Schirmer, Naomi Yudanin, David Artis, Isabel J. Latorre, Ramnik J. Xavier, Anne-Laure Flamar, Donna L. Farber, Elia D. Tait Wojno, Joseph J.C. Thome
المصدر: Immunity. 50:505-519.e4
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, Adolescent, Immunology, Inflammation, Biology, Article, Limited access, Genetic Heterogeneity, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Immunity, medicine, Animals, Humans, Immunology and Allergy, Lymphocytes, Child, skin and connective tissue diseases, Tissue homeostasis, Aged, Genetic heterogeneity, Innate lymphoid cell, Infant, Newborn, Infant, Middle Aged, Immunity, Innate, Cell biology, body regions, Tissue specificity, 030104 developmental biology, Infectious Diseases, Anatomical sites, Organ Specificity, Child, Preschool, 030220 oncology & carcinogenesis, Female, medicine.symptom, Transcriptome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c28d059d94101c24e1a84fa0e13fc6f
https://doi.org/10.1016/j .immuni.2019.01.012 -
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المؤلفون: L. Dick, Mark S. Guyer, D. Mecenas, William C. Spencer, Ming Sin Cheung, Sebastian D. Mackowiak, Tao Liu, A. Vielle, Abby F. Dernburg, Mitzi Morris, Bradley I. Arshinoff, Sheldon J. McKay, Amber Leahey, Thea A. Egelhofer, Lukas Habegger, Michael Snyder, Teruaki Takasaki, Roger P. Alexander, Stuart K. Kim, Ashish Agarwal, Ting Han, A. Leo Iniguez, Eric L. Van Nostrand, Gos Micklem, S. Taing, Ekta Khurana, Joel Rozowsky, Beijing Wu, Steven Henikoff, Adrian Carr, Philip Green, Angie S. Hinrichs, A. Muroyama, Jason D. Lieb, Paul Lloyd, Yaniv Lubling, P. Scheid, Kevin Y. Yip, Stefan R. Henz, Chao Cheng, Jiang Du, Mei Zhong, P. Alves, Elicia Preston, Zhi John Lu, Vishal Khivansara, Robert H. Waterston, J. Janette, C. Slightam, Frank J. Slack, David M. Miller, Eo Stinson, Nikolaus Rajewsky, Eran Segal, Jing Leng, Tony Hyman, R. Robilotto, C. Shou, Gunnar Rätsch, Eric C. Lai, Mihail Sarov, X. Shirley Liu, Isabel J. Latorre, A. Chateigner, Francois Gullier, Raymond K. Auerbach, W. James Kent, Sergio Contrino, Jeremy Brouillet, Lincoln Stein, T. Phippen, Andrea Sboner, Marco Mangone, Georg Zeller, Hoang Pham, Mark Gerstein, Michael J. MacCoss, Siew Loon Ooi, Cathleen M. Brdlik, D. Vafeados, Nicole L. Washington, Andreas Rechtsteiner, Peter J. Good, Susan Strome, Galt P. Barber, Kristin C. Gunsalus, John I. Murray, Valerie Reinke, Luke Dannenberg, Masaomi Kato, M. Jensen, X. Feng, John Kim, Kahn Rhrissorrakrai, H. Holster, Kohta Ikegami, Christina M. Whittle, M. Gutwein, Rachel Lyne, Wei Niu, Richard J.H. Smith, LaDeana W. Hillier, P. Kolasinska-Zwierz, Heidi Rosenbaum, Andréa C. Dosé, Xingliang Zhou, Marc D. Perry, Rajkumar Sasidharan, Rebecca F. Lowdon, Arshad Desai, Z. Zha, J. Brennan, Guilin Wang, P. Ruzanov, Brent Ewing, Gennifer E. Merrihew, Kim Rutherford, Reto Gassmann, Elise A. Feingold, Fabio Piano, Julie Ahringer, E. Kephart, Lucas Lochovsky, Sevinc Ercan, Suzanna E. Lewis, Ksenia Voronina, Koon-Kiu Yan, Jorja G. Henikoff, Hyunjin Shin, Hiram Clawson, Ghia Euskirchen
المصدر: Science. 330:1775-1787
مصطلحات موضوعية: Gene expression profiling, Genetics, Multidisciplinary, biology, Chromosome, Genomics, Genome project, biology.organism_classification, Gene, Genome, Caenorhabditis elegans, Chromatin
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المؤلفون: Gautam Goel, Szu Yu Kuo, Kara L. Conway, Kara G. Lassen, Dorothea Maetzel, Rudolf Jaenisch, Petric Kuballa, Sovan Sarkar, Alykhan F. Shamji, Leslie N. Aldrich, Vlado Dančík, Isabel J. Latorre, Paul A. Clemons, Adam B. Castoreno, Ramnik J. Xavier, Stuart L. Schreiber
المصدر: Proceedings of the National Academy of Sciences. 112
مصطلحات موضوعية: Genetics, Medical, Green Fluorescent Proteins, Induced Pluripotent Stem Cells, Interleukin-1beta, Cellular homeostasis, Context (language use), Biology, Models, Biological, Small Molecule Libraries, Niemann-Pick C1 Protein, Autophagy, medicine, Humans, Enhancer, Cell Aggregation, Neurons, Membrane Glycoproteins, Multidisciplinary, Bacteria, Neurodegeneration, Intracellular Signaling Peptides and Proteins, Niemann-Pick Disease, Type C, medicine.disease, Phenotype, Human genetics, Cell aggregation, High-Throughput Screening Assays, Cell biology, PNAS Plus, Carrier Proteins, Peptides, HeLa Cells
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المؤلفون: Ronald T. Javier, Craig C. Garner, Lawrence A. Donehower, Monica J. Justice, Kristopher K. Frese, Sang-Hyuk Chung, Stephen N. Jones, Alan Bernstein, Georgina Caruana, Isabel J. Latorre
المصدر: The EMBO Journal. 25:1406-1417
مصطلحات موضوعية: Tumor suppressor gene, Class I Phosphatidylinositol 3-Kinases, Nerve Tissue Proteins, Phosphatidylinositol 3-Kinases, Biology, Transfection, Article, General Biochemistry, Genetics and Molecular Biology, law.invention, Discs Large Homolog 1 Protein, Mice, law, Animals, Humans, Molecular Biology, PI3K/AKT/mTOR pathway, General Immunology and Microbiology, Tumor Suppressor Proteins, General Neuroscience, Cell Membrane, Oncogene Proteins, Viral, Cell Transformation, Viral, Molecular biology, SAP90-PSD95 Associated Proteins, Transport protein, Cell biology, Protein Transport, Genes, ras, DLG1, biology.protein, Suppressor, Function (biology)
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المؤلفون: Michael H. Roh, Robert S. Weiss, Isabel J. Latorre, Kristopher K. Frese, Ronald T. Javier, Ben Margolis
المصدر: Journal of Cell Science. 118:4283-4293
مصطلحات موضوعية: Polarity (physics), PDZ domain, Plasma protein binding, Biology, DNA-binding protein, Article, Tight Junctions, Dogs, Chlorocebus aethiops, Cell polarity, Animals, Humans, Eye Proteins, Claudin, Tight Junction Proteins, Tight junction, Membrane Proteins, Epithelial Cells, Oncogene Proteins, Viral, Cell Biology, Cell biology, DNA-Binding Proteins, Membrane protein, COS Cells, DNA, Viral, Adenovirus E4 Proteins, Plasmids, Protein Binding
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المؤلفون: Thea A. Egelhofer, Maxwell W. Libbrecht, Michael M. Hoffman, Ju Han Kim, David M. MacAlpine, William Stafford Noble, Charles B. Epstein, Alex Appert, Q. Brent Chen, Michael J. Pazin, Peter J. Park, Manolis Kellis, Aki Minoda, Sheng'en Shawn Hu, Moritz Herrmann, Chitra V. Kotwaliwale, Jason A. Belsky, Jason D. Lieb, Susan Strome, Sasha A. Langley, Tingting Gu, Sevinc Ercan, Youngsook L. Jung, Kyung-Ah Sohn, Joshua W. K. Ho, Daniel He, Xikun Duan, Gary H. Karpen, Erica Larschan, Noam Shoresh, Isabel J. Latorre, Tao Liu, Bradley E. Bernstein, Bo Qin, Artyom A. Alekseyenko, Ron A.-J. Chen, Nicole C. Riddle, Przemyslaw Stempor, A. Vielle, Jacob M. Garrigues, Andreas Rechtsteiner, Huiling Xue, Tess E. Jeffers, Xiaole Shirley Liu, Burak H. Alver, Sarah K. Bowman, Anshul Kundaje, Stephen C. J. Parker, Peter V. Kharchenko, Soohyun Lee, Richard W. Park, Kohta Ikegami, Elise A. Feingold, Julie Ahringer, Psalm Haseley, Annette Plachetka, P. Kolasinska-Zwierz, Sarah C. R. Elgin, Vincenzo Pirrotta, Abby F. Dernburg, Eric Bishop, Yan Dong, Peter J. Good, Michael Y. Tolstorukov, Francesco Ferrari, Thomas D. Tullius, Xueqiu Lin, Yuri B. Schwartz, Chengyang Wang, Daniel S. Day, Dalal Asker, Andréa C. Dosé, Nischay Kumar, Christina M. Whittle, Robert E. Kingston, Nils Gehlenborg, Mitzi I. Kuroda, Hoang N. Pham
المساهمون: Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science, Kundaje, Anshul, Kumar, Nischay, Kellis, Manolis, Day, Daniel S.
المصدر: Nature, vol 512, iss 7515
Natureمصطلحات موضوعية: DNA Replication, Histone-modifying enzymes, Enhancer Elements, Heterochromatin, General Science & Technology, 1.1 Normal biological development and functioning, Centromere, Article, Cell Line, Histones, Promoter Regions, Species Specificity, Genetic, Underpinning research, Genetics, Nucleosome, Animals, Humans, Caenorhabditis elegans, Pericentric heterochromatin, ChIA-PET, Epigenomics, Multidisciplinary, Nuclear Lamina, biology, Human Genome, Molecular Sequence Annotation, Chromatin Assembly and Disassembly, Chromatin, Nucleosomes, Histone, Drosophila melanogaster, Evolutionary biology, Generic Health Relevance, biology.protein, Immunization, Epigenesis
وصف الملف: application/pdf
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المؤلفون: Leslie L. Domier, Isabel J. Latorre, Cleora J. D'Arcy
المصدر: Canadian Journal of Plant Pathology. 18:424-428
مصطلحات موضوعية: Barley Yellow Dwarf Viruses, Botany, Plant Science, Biology, Agronomy and Crop Science
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المؤلفون: Sarah C. R. Elgin, Tingting Gu, Daniel S. Day, Yuri B. Schwartz, Peter V. Kharchenko, Gregory A. Shanower, Gary H. Karpen, Vincenzo Pirrotta, Ying Luu, Daniela Linder-Basso, Ming Sin Cheung, P. Kolasinska-Zwierz, Andrey A. Gorchakov, Jason D. Lieb, Susan Strome, Artyom A. Alekseyenko, Aki Minoda, A. Vielle, R. David Hawkins, Kyungjoon Lee, Marc D. Perry, Sarah Gadel, Que-Minh Ngo, Isabel J. Latorre, Nicole C. Riddle, Sarit Klugman, Mitzi I. Kuroda, Andreas Rechtsteiner, Julie Ahringer, Peter J. Park, Bing Ren, Thea A. Egelhofer, Samantha Kuan
المصدر: Nature structural & molecular biology, vol 18, iss 1
Nature structural & molecular biologyمصطلحات موضوعية: Quality Control, Chromatin Immunoprecipitation, Blotting, Western, Immunoblotting, Biophysics, Dot blot, Biology, Medical and Health Sciences, Article, Antibodies, Histones, 03 medical and health sciences, 0302 clinical medicine, Western blot, Structural Biology, Antibody Specificity, medicine, Genetics, Animals, Drosophila Proteins, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, Protein Processing, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, Blotting, Post-Translational, Reproducibility of Results, Biological Sciences, biology.organism_classification, Molecular biology, 3. Good health, Blot, Histone, Drosophila melanogaster, Chemical Sciences, biology.protein, Generic health relevance, Antibody, Chromatin immunoprecipitation, Protein Processing, Post-Translational, Western, 030217 neurology & neurosurgery, Drosophila Protein, Biotechnology, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: X. Shirley Liu, Isabel J. Latorre, Tao Liu, P. Kolasinska-Zwierz, Thomas A. Down, Julie Ahringer
المصدر: Nature genetics
مصطلحات موضوعية: Transcription, Genetic, Biology, Exon shuffling, Methylation, Article, Histones, 03 medical and health sciences, Splicing factor, Exon, Open Reading Frames, 0302 clinical medicine, Histone H1, Genetics, Histone code, Animals, Gene Silencing, Protein Methyltransferases, Caenorhabditis elegans, 030304 developmental biology, 0303 health sciences, Binding Sites, Lysine, Alternative splicing, Chromosome Mapping, Exons, Histone-Lysine N-Methyltransferase, Chromatin, Introns, Alternative Splicing, Gene Expression Regulation, RNA splicing, Histone Methyltransferases, Tandem exon duplication, 030217 neurology & neurosurgery, Protein Binding
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المؤلفون: Kristopher K. Frese, Ronald T. Javier, Isabel J. Latorre
المصدر: Tight Junctions ISBN: 9780387332017
مصطلحات موضوعية: Tight junction, Cell culture, Gene expression, medicine, Motility, Signal transduction, Biology, medicine.disease, Barrier function, In vitro, Metastasis, Cell biology
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المؤلفون: Nancy K. McCoppin, Isabel J. Latorre, Todd A. Steinlage, Glen L. Hartman, Leslie L. Domier
المصدر: Archives of virology. 148(10)
مصطلحات موضوعية: Asia, Potyvirus, Soybean mosaic virus, law.invention, Viral Proteins, law, Virology, Animals, Peptide sequence, Polymerase chain reaction, Phylogeny, Plant Diseases, Genetics, biology, Phylogenetic tree, Potyviridae, General Medicine, Sequence Analysis, DNA, biology.organism_classification, Aphis, Cysteine Endopeptidases, Aphids, North America, Capsid Proteins, Soybeans, Restriction fragment length polymorphism, Polymorphism, Restriction Fragment Length
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المؤلفون: Isabel J. Latorre, Julie Ahringer, Thomas A. Down, Ming Sin Cheung
المساهمون: Ahringer, Julie [0000-0002-7074-4051], Apollo - University of Cambridge Repository
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Chromatin Immunoprecipitation, DNA nanoball sequencing, Sequence assembly, Computational biology, Biology, DNA sequencing, Deep sequencing, 03 medical and health sciences, 0302 clinical medicine, Genetics, Animals, Caenorhabditis elegans, Illumina dye sequencing, ChIP-exo, 030304 developmental biology, Base Composition, 0303 health sciences, Shotgun sequencing, High-Throughput Nucleotide Sequencing, Sequence Analysis, DNA, DNA, Helminth, ChIP-sequencing, Methods Online, Algorithms, 030217 neurology & neurosurgery
وصف الملف: application/pdf