المؤلفون: Gittings, Lauren M, Foti, Sandrine C, Benson, Bridget C, Gami-Patel, Priya, Isaacs, Adrian M, Lashley, Tammaryn

المصدر: Translational Neuroscience

مصطلحات موضوعية: FTLD, FUS, Frontotemporal lobar degeneration, Heterogeneous nuclear ribonucleoprotein, hnRNP Q, hnRNP R, Adult, Aged, 80 and over, Female, Frontotemporal Lobar Degeneration (metabolism, pathology), Heterogeneous-Nuclear Ribonucleoproteins (metabolism), Hippocampus (metabolism, Humans, Inclusion Bodies (metabolism, Intranuclear Inclusion Bodies (metabolism, Male, Middle Aged, RNA-Binding Protein FUS (metabolism), Temporal Lobe (metabolism

Relation: https://scholar.barrowneuro.org/neurobiology/2310; https://doi.org/10.1186/s40478-019-0673-y

الاتاحة: https://scholar.barrowneuro.org/neurobiology/2310
https://doi.org/10.1186/s40478-019-0673-y

المؤلفون: Mizielinska, Sarah, Ridler, Charlotte E, Balendra, Rubika, Thoeng, Annora, Woodling, Nathan S, Grässer, Friedrich A, Plagnol, Vincent, Lashley, Tammaryn, Partridge, Linda, Isaacs, Adrian M

المصدر: Mizielinska , S , Ridler , C E , Balendra , R , Thoeng , A , Woodling , N S , Grässer , F A , Plagnol , V , Lashley , T , Partridge , L & Isaacs , A M 2017 , ' Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration ' , Acta Neuropathologica Communications , vol. 5 , no. 1 , 29 . https://doi.org/10.1186/s40478-017-0432-x

مصطلحات موضوعية: Animals, Genetically Modified, C9orf72 Protein, Cell Nucleolus/metabolism, Cell Nucleus Size/genetics, DNA Repeat Expansion, Drosophila, Fluorescent Antibody Technique, Frontal Lobe/metabolism, Frontotemporal Lobar Degeneration/genetics, Humans, Imaging, Three-Dimensional, In Situ Hybridization, Fluorescence, Intranuclear Inclusion Bodies/metabolism, Microscopy, Confocal, Neurons/metabolism, Proteins/genetics, Stress, Physiological/genetics

وصف الملف: application/pdf

Relation: https://kclpure.kcl.ac.uk/portal/en/publications/54381054-d4ae-49c6-87e5-c3ff9ada4067

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/54381054-d4ae-49c6-87e5-c3ff9ada4067
https://doi.org/10.1186/s40478-017-0432-x
https://kclpure.kcl.ac.uk/ws/files/98315632/Mizielinska_et_al_Acta_Comm_2017_C9_Nucleolar_Dysfunction.pdf

المؤلفون: Voisset, Edwige, Moravcsik, Eva, Stratford, Eva W, Jaye, Amie, Palgrave, Christopher J, Hills, Robert K, Salomoni, Paolo, Kogan, Scott C, Solomon, Ellen, Grimwade, David

المصدر: Blood 131(6), 636-648 (2018). doi:10.1182/blood-2017-07-794784

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Animals, Cell Transformation, Neoplastic: genetics, Neoplastic: metabolism, DNA Damage: genetics, DNA End-Joining Repair: genetics, DNA Repair: genetics, Intranuclear Inclusion Bodies: genetics, Intranuclear Inclusion Bodies: metabolism, Leukemia, Promyelocytic, Acute: genetics, Acute: metabolism, Acute: pathology, Mice, Transgenic, Mutagenesis: genetics, Oncogene Proteins, Fusion: genetics, Fusion: metabolism, Promyelocytic Leukemia Protein: genetics, Promyelocytic Leukemia Protein: physiology, Signal Transduction: genetics, Fusion, Pml protein, mouse, Promyelocytic Leukemia Protein, promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0006-4971; info:eu-repo/semantics/altIdentifier/issn/1528-0020; info:eu-repo/semantics/altIdentifier/pmid/pmid:29191918; https://pub.dzne.de/record/139784; https://pub.dzne.de/search?p=id:%22DZNE-2020-06106%22

الاتاحة: https://pub.dzne.de/record/139784
https://pub.dzne.de/search?p=id:%22DZNE-2020-06106%22

المؤلفون: Daniels, Matthew J, Marson, Alexander, Venkitaraman, Ashok R

المصدر: Daniels , M J , Marson , A & Venkitaraman , A R 2004 , ' PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein ' , Nature Structural and Molecular Biology , vol. 11 , no. 11 , pp. 1114-21 . https://doi.org/10.1038/nsmb837

مصطلحات موضوعية: Animals, Cell Cycle, Cell Cycle Proteins/metabolism, Cell Line, Cell Nucleus/metabolism, Chromosome Aberrations, Cloning, Molecular, DNA, Complementary/metabolism, Fluorescence Resonance Energy Transfer, Green Fluorescent Proteins/metabolism, Humans, Immunoprecipitation, Intranuclear Inclusion Bodies/metabolism, Mice, Microscopy, Fluorescence, Mitosis, Models, Genetic, Mutation, Neoplasm Proteins/chemistry, Nuclear Proteins/chemistry, Poly-ADP-Ribose Binding Proteins, Promyelocytic Leukemia Protein, Protein Binding, Recombinant Fusion Proteins/metabolism, Time Factors, Transcription Factors/chemistry

الاتاحة: https://research.manchester.ac.uk/en/publications/a731e7e4-58a2-486d-b083-53bfc1973e6c
https://doi.org/10.1038/nsmb837