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المؤلفون: Yuxiao Liu, Xiaozhen Dai, Xiao-Lin Liu, Aoyuan Cui, Feng Shen, Feng-Zhi Xin, Weitong Su, Jian-Gao Fan, Yamei Han, Ze-Hua Zhao, Feifei Zhang, Yaqian Xue, Yu Li, Genxiang Cai, Zhengshuai Liu, Zi-Xuan Wang, Qin Pan, Jinyun Bai, Zhimin Hu, Tian-Yi Ren, Fengguang Ma, Da Zhou
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, Hepatic Lipogenesis, RC799-869, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, GST, glutathione S-transferase, Mice, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Insulin, Phosphorylation, Insig, insulin-induced gene, Original Research, Chemistry, Kinase, Gastroenterology, Sodium butyrate, Diseases of the digestive system. Gastroenterology, 030211 gastroenterology & hepatology, medicine.medical_specialty, Insulin-Induced Gene, LKB1, ATP, adenosine triphosphate, MAP Kinase Signaling System, NaB, sodium butyrate, Butyrate, Diet, High-Fat, Models, Biological, 03 medical and health sciences, LKB1, liver kinase B1, NAFLD, Internal medicine, PYY, peptide YY, medicine, Animals, Humans, GLP-1, glucagon-like peptide 1, Protein kinase A, Hepatology, Lipogenesis, AMPK, Lipid Metabolism, medicine.disease, Sodium Butyrate, AMPK, AMP-activated protein kinase, Disease Models, Animal, 030104 developmental biology, Endocrinology, Gene Expression Regulation, AMP, adenosine monophosphate, Dietary Supplements, Hepatocytes, Butyric Acid, NAFLD, nonalcoholic fatty liver disease, Liver function, Steatosis
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المؤلفون: Tirthadipa Pradhan-Sundd
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1199-1201 (2021)مصطلحات موضوعية: Male, Arteriosclerosis, SREBP, sterol regulatory element-binding protein, CREB3L3, FGF21, fibroblast growth factor 21, Bioinformatics, CREB3L3, cAMP responsive element-binding protein 3 like 3, Mice, Enterohepatic Circulation, Cyclic AMP Response Element-Binding Protein, Insig, insulin-induced gene, Original Research, GFP, green fluorescent protein, Mice, Knockout, Sterol Regulatory Element Binding Proteins, TBA, total bile acid, WD, Western diet, TG, triglyceride, Chemistry, Gastroenterology, Editorial, Hyperlipidemia, LPL, lipoprotein lipase, Female, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 1, HDL, high-density lipoprotein, Hyperlipidemias, SREBP, ER, endoplasmic reticulum, Competition (economics), Tg, transgenic, FFA, free fatty acid, medicine, Animals, Humans, lcsh:RC799-869, KO, knockout, PPARα, peroxisome proliferator-activated receptor alpha, Hepatology, PLA, proximity ligation assay, S1P, site-1 protease, Lipogenesis, SREBF, sterol regulatory element-binding factor, VLDL, very-low-density lipoprotein, Atherosclerosis, Lipid Metabolism, medicine.disease, Sterol regulatory element-binding protein, Mice, Inbred C57BL, TC, total cholesterol, Gene Expression Regulation, Receptors, LDL, Apo, apolipoprotein, HPLC, high-performance liquid chromatography, HSV, herpes simplex virus, lcsh:Diseases of the digestive system. Gastroenterology, LXR, liver X receptor
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المؤلفون: Meljon, Anna, Wang, Yuqin, Griffiths, William J.
المصدر: Biochemical and Biophysical Research Communications
Meljon, A, Wang, Y & Griffiths, W J 2014, ' Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse ', Biochemical and Biophysical Research Communications, vol. 446, no. 3, pp. 768-774 . https://doi.org/10.1016/j.bbrc.2014.01.153مصطلحات موضوعية: Lxr, liver x receptor, Biophysics, MSn, mass spectrometry with multistage fragmentation, Biochemistry, Article, Mice, Oxysterol, RP, reversed phase, polycyclic compounds, Cholesterol 24-Hydroxylase, Brain/metabolism, Animals, Hydroxycholesterols/metabolism, FT, Fourier transform, Molecular Biology, SCAP, SREBP cleavage-activating protein, 24S,25-Epoxycholesterol, ComputingMethodologies_COMPUTERGRAPHICS, Mice, Knockout, LC, liquid chromatography, Brain, INSIG, insulin induced gene, Cell Biology, Steroid Hydroxylases/genetics, SREBP, sterol regulatory-element binding protein, RIC, reconstructed ion chromatogram, Hydroxycholesterols, Cyp, cytochrome P450, Cholesterol, Cyp46a1, SPE, solid phase extraction, MS, mass spectrometry or mass spectrum, 24S-Hydroxycholesterol, 24R-Hydroxycholesterol, Steroid Hydroxylases, ESI, electrospray ionisation, lipids (amino acids, peptides, and proteins), Female, Cholesterol/analogs & derivatives, wt, wild type, GP, Girard P reagent, MRM, multiple reaction monitoring, TLR, Toll-like receptor
وصف الملف: application/pdf
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المؤلفون: Wang, Yuchen, Karu, Kersti, Meljon, Anna, Turton, John, Yau, Joyce L., Seckl, Jonathan R., Wang, Yuqin, Griffiths, William J.
المصدر: Wang, Y, Karu, K, Meljon, A, Turton, J, Yau, J L, Seckl, J R, Wang, Y & Griffiths, W J 2014, ' 24S,25-Epoxycholesterol in mouse and rat brain ', Biochemical and Biophysical Research Communications, vol. 449, no. 2, pp. 229–234 . https://doi.org/10.1016/j.bbrc.2014.05.012
Biochemical and Biophysical Research Communicationsمصطلحات موضوعية: Male, RICs, reconstructed ion chromatogram, APCI, atmospheric pressure chemical ionisation, MSn, mass spectrometry with multistage fragmentation, Biochemistry, 25-epoxide, Rats, Sprague-Dawley, Mice, 24S-hydroxycholesterol, 3β,7α-Dihydroxycholest-5-en-24S,25-epoxide, HMG-CoA, 3-hydroxy-3-methyl-glutaryl-CoA, LIT, linear ion-trap, Ctx, cortex, Insig, insulin-induced gene, Mice, Knockout, LC, liquid chromatography, DDA, data dependent analysis, Brain, BBB, blood brain barrier, Sterols, Cholesterol, CYP or Cyp, cytochrome P450, 3β,7α-Dihydroxycholest-5-en-24S, SREBP-2, sterol regulatory element-binding protein-2, Female, wt, wild type, GC, gas chromatography, Metabolic Networks and Pathways, Spectrometry, Mass, Electrospray Ionization, LXRs or Lxrs, liver X receptors, Cytochrome P450 Family 7, Biophysics, Mevalonic Acid, GP, Girard P, CNS, central nervous system, Models, Biological, Article, ER, endoplasmic reticulum, Mice, Congenic, Cytochrome P450 7b1, Animals, SCAP, SREBP-cleavage activating protein, Molecular Biology, 24S,25-Epoxycholesterol, ComputingMethodologies_COMPUTERGRAPHICS, API, atmospheric pressure ionisation, Cell Biology, Rats, Mice, Inbred C57BL, MS, mass spectrometry or mass spectrum, Steroid Hydroxylases, ESI, electrospray ionisation, Vm, ventral midbrain, MRM, multiple reaction monitoring
وصف الملف: application/pdf