المؤلفون: Sunil Kumar Saini, Andreas Due Ørskov, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Staffan Holmberg-Thydén, Annie Borch, Kathrine Valentini Jensen, Govardhan Anande, Amalie Kai Bentzen, Andrea Marion Marquard, Tripti Tamhane, Marianne Bach Treppendahl, Anne Ortved Gang, Inge Høgh Dufva, Zoltan Szallasi, Nicola Ternette, Anders Gorm Pedersen, Aron Charles Eklund, John Pimanda, Kirsten Grønbæk, Sine Reker Hadrup

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d34a194f6b844353a08c2553d7fdeaee

المؤلفون: Michael Stangegaard, Inge Høgh Dufva, Martin Dufva

المصدر: BioTechniques, Vol 40, Iss 5, Pp 649-657 (2006)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

URL الوصول: https://doaj.org/article/7fcae8de65fb4dd7aa43ba7e00672afd

المؤلفون: Lars Möllgård, Leonie Saft, Marianne Bach Treppendahl, Ingunn Dybedal, Jan Maxwell Nørgaard, Jan Astermark, Elisabeth Ejerblad, Hege Garelius, Inge Høgh Dufva, Monika Jansson, Martin Jädersten, Lars Kjeldsen, Olle Linder, Lars Nilsson, Hanne Vestergaard, Anna Porwit, Kirsten Grønbæk, Eva Hellström Lindberg

المصدر: Haematologica, Vol 96, Iss 7 (2011)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/6025; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/141d2a56ccab4820add460edcc817c01

المؤلفون: Anne Ortved Gang, Kirsten Grønbæk, Mette K. Andersen, Marie Fredslund Breinholt, Mohammad Kadivar, Inge Marie Svane, Staffan Holmberg-Thydén, Sine Reker Hadrup, Lone Schejbel, Daniel El Fassi, Inge Høgh Dufva

المصدر: Cancer immunology, immunotherapy : CII. 71(2)

مصطلحات موضوعية: Male, Cancer Research, Antimetabolites, Antineoplastic, Combination therapy, Maximum Tolerated Dose, medicine.medical_treatment, Immunology, Azacitidine, Cancer Vaccines, Epigenesis, Genetic, Antigens, Neoplasm, medicine, Immunology and Allergy, Humans, Tissue Distribution, Aged, PRAME, business.industry, Immunotherapy, Prognosis, Oncology, Myelodysplastic Syndromes, Peptide vaccine, Cancer research, Cancer/testis antigens, Drug Therapy, Combination, Female, Cancer vaccine, business, Epigenetic therapy, medicine.drug, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cafa8b62e56b380748d6b92a2839dd2
https://pubmed.ncbi.nlm.nih.gov/34218294

المؤلفون: Marie Fredslund Breinholt, Staffan Holmberg-Thydén, Mohammad Kadivar, Inge Høgh Dufva, Daniel El Fassi, Inge Marie Svane, Kirsten Grønbæk, Mette K. Andersen, Sine Reker Hadrup, Lone Schejbel, Anne Ortved Gang

المصدر: Blood. 136:23-24

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Immunology, Azacitidine, Phases of clinical research, Cancer, Cell Biology, Hematology, medicine.disease, Biochemistry, Tumor associated antigen, Vaccination, Internal medicine, medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a95807d74ae0cb3c572a00fee050664a
https://doi.org/10.1182/blood-2020-142806

المؤلفون: Véronique Maguer-Satta, Sandrine Hayette, Martin C. Müller, Wei Zhou, Eric Lippert, Jane F. Apperley, Gabriel Etienne, Charles Chuah, Catherine Roche-Lestienne, Jorge E. Cortes, Michael J. Mauro, Mauricette Michallet, Dong-Wook Kim, Franç ois X. Mahon, Simona Soverini, Franck E. Nicolini, Stephane Morisset, John M. Goldman, Andreas Hochhaus, Inge Høgh Dufva, Amr R. Ibrahim, David Marin, Senaka Peter, Giovanni Martinelli, Hélène Labussière

المساهمون: Nicolini FE, Ibrahim AR, Soverini S, Martinelli G, Müller MC, Hochhaus A, Dufva IH, Kim DW, Cortes J, Mauro MJ, Chuah C, Labussière H, Morisset S, Roche-Lestienne C, Lippert E, Hayette S, Peter S, Zhou W, Maguer-Satta V, Michallet M, Goldman J, Apperley JF, Mahon FX, Marin D, Etienne G.

المصدر: Haematologica. 98:1510-1516

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Adolescent, Fusion Proteins, bcr-abl, Genes, abl, Chronic phase chronic myelogenous leukemia, Cohort Studies, Young Adult, hemic and lymphatic diseases, Internal medicine, TYROSINE KINASE INHIBITORS, Humans, Medicine, Prospective Studies, BCR-ABL, Protein Kinase Inhibitors, Survival rate, Aged, Retrospective Studies, ABL, business.industry, Imatinib, Articles, Hematology, Middle Aged, medicine.disease, Survival Rate, Leukemia, Imatinib mesylate, Drug Resistance, Neoplasm, Leukemia, Myeloid, Chronic-Phase, Mutation, Immunology, ABL MUTATIONS, Female, business, Tyrosine kinase, medicine.drug, Chronic myelogenous leukemia

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1493c0de2e8c7d3d789fd82875965edc
https://doi.org/10.3324/haematol.2012.080234

المؤلفون: Peter A. Jones, Anne-Mette Bjerregaard, Sunil Kumar Saini, Inge Høgh Dufva, Marianne Bach Treppendahl, Gangning Liang, Hitoshi Otani, Andreas Due Ørskov, Kirsten Grønbæk, Staffan Holmberg, Anne Ortved Gang, Aron Charles Eklund, Sine Reker Hadrup

المصدر: Leukemia Research. 55:S66-S67

مصطلحات موضوعية: Cancer Research, Oncology, Antigen specific, Cancer research, Endogeny, Hematology, Epigenetics, Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::faf54685530923c38fbed822c6dc100c
https://doi.org/10.1016/s0145-2126(17)30220-5

المؤلفون: Andreas Due Ørskov, Johanne B. Mogensen, Lykkesfeldt Jens, Hitoshi Otani, Kirsten Grønbæk, Petra Hajkova, Linn Gillberg, Peter A. Jones, Ammar Nasif, Inge Høgh Dufva, Minmin Liu, Jakob Werner Hansen, Zachary Madaj

المصدر: Blood. 132:3079-3079

مصطلحات موضوعية: medicine.medical_specialty, Myeloid, Vitamin C, business.industry, Immunology, Azacitidine, Cell Biology, Hematology, Ascorbic acid, Biochemistry, Endocrinology, medicine.anatomical_structure, Internal medicine, Oral vitamin, Medicine, In patient, Epigenetics, Ascorbic Acid Deficiency, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fedcd487354dccba182b83d019b7bd07
https://doi.org/10.1182/blood-2018-99-111525

المؤلفون: Jan Maxwell Nørgaard, Mette K. Andersen, Birgitte Preiss, Lone Smidstrup Friis, Marianne Tang Severinsen, Lene Sofie Granfeldt Østgård, Mette Nørgaard, Inge Høgh Dufva, Claus Werenberg Marcher, Bruno C. Medeiros, H Sengeløv, Eigil Kjeldsen

المصدر: Granfeldt Østgård, L S, Medeiros, B C, Sengeløv, H, Nørgaard, M, Andersen, M K, Dufva, I H, Friis, L S, Kjeldsen, E, Marcher, C W, Preiss, B, Severinsen, M & Nørgaard, J M 2015, ' Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia : A National Population-Based Cohort Study ', Journal of Clinical Oncology, vol. 33, no. 31, pp. 3641-3649 . https://doi.org/10.1200/JCO.2014.60.0890
Granfeldt Østgård, L S, Medeiros, B C, Sengeløv, H, Nørgaard, M, Andersen, M K, Dufva, I H, Friis, L S, Kjeldsen, E, Marcher, C W, Preiss, B, Severinsen, M & Nørgaard, J M 2015, ' Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia : A National Population-Based Cohort Study ', Journal of Clinical Oncology, vol. 33, no. 31, pp. 3641-9 . https://doi.org/10.1200/JCO.2014.60.0890

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Myeloid, Adolescent, Denmark, Population, Chronic myelomonocytic leukemia, Antineoplastic Agents, Therapy-Related Acute Myeloid Leukemia, Kaplan-Meier Estimate, Cohort Studies, Young Adult, Internal medicine, hemic and lymphatic diseases, Neoplasms, medicine, Humans, Registries, education, Aged, Aged, 80 and over, education.field_of_study, Myeloproliferative Disorders, business.industry, Myelodysplastic syndromes, Remission Induction, Myeloid leukemia, Neoplasms, Second Primary, Middle Aged, medicine.disease, Prognosis, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Treatment Outcome, Hematologic disease, Karyotyping, Myelodysplastic Syndromes, Immunology, Regression Analysis, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a4a4040d585673f48bcae56638cf03
https://pubmed.ncbi.nlm.nih.gov/26304885

المؤلفون: Inge Høgh Dufva, K Brøndum-Nielsen, Lars Kjeldsen, J Pedersen-Bjergaard, Mette K. Andersen

المصدر: Leukemia. 16:1390-1393

مصطلحات موضوعية: Cancer Research, Chemotherapy, medicine.medical_treatment, Aneuploidy, Chromosomal translocation, Hematology, Biology, Philadelphia chromosome, medicine.disease, Trisomy 8, Haematopoiesis, Imatinib mesylate, Oncology, hemic and lymphatic diseases, Immunology, medicine, Cancer research, Trisomy, neoplasms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bb6e130afb06ec31975cd91a4b831c2e
https://doi.org/10.1038/sj.leu.2402634

المؤلفون: Henrik Sengeløv, Mette Nørgaard, Lone Smidstrup Friis, Marianne Tang Severinsen, Claus Werenberg Marcher, Lene Sofie Granfeldt Østgård, Inge Høgh Dufva, Jan Maxwell Nørgaard

المصدر: Ostgård, L S G, Nørgaard, J M, Sengeløv, H, Severinsen, M, Smidstrup Friis, L, Werenberg Marcher, C, Høgh Dufva, I & Nørgaard, M 2015, ' Comorbidity and performance status in acute myeloid leukemia patients : a nation-wide population-based cohort study ', Leukemia, vol. 29, no. 3, pp. 548-555 . https://doi.org/10.1038/leu.2014.234
Østgård, L S G, Nørgaard, J M, Sengeløv, H, Severinsen, M, Friis, L S, Marcher, C W, Dufva, I H & Nørgaard, M 2015, ' Comorbidity and performance status in acute myeloid leukemia patients : a nation-wide population-based cohort study ', Leukemia, pp. 548-55 . https://doi.org/10.1038/leu.2014.234
Ostgård, L S G, Nørgaard, J M, Sengeløv, H, Severinsen, M, Friis, L S, Marcher, C W, Dufva, I H & Nørgaard, M 2015, ' Comorbidity and performance status in acute myeloid leukemia patients : a nation-wide population-based cohort study ', Leukemia, vol. 29, no. 3, pp. 548–555 . https://doi.org/10.1038/leu.2014.234

مصطلحات موضوعية: Adult, Lung Diseases, Male, Cancer Research, medicine.medical_specialty, Adolescent, Denmark, Leukemia, Myeloid, Acute/drug therapy, Antineoplastic Agents, Comorbidity, Cohort Studies, Internal medicine, mental disorders, Lung Diseases/drug therapy, medicine, Humans, Registries, Survival analysis, Aged, Aged, 80 and over, Performance status, business.industry, Mortality rate, Remission Induction, Antineoplastic Agents/therapeutic use, Age Factors, Myeloid leukemia, Hematology, Middle Aged, medicine.disease, Survival Analysis, Denmark/epidemiology, Confidence interval, Leukemia, Leukemia, Myeloid, Acute, Oncology, Cardiovascular Diseases, Physical therapy, Female, Cardiovascular Diseases/drug therapy, business, Cohort study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e110351e80a26f002d5e79cf13f8d53d
https://pubmed.ncbi.nlm.nih.gov/25092141

المؤلفون: Niklas Brywe, Börje Ridell, Jan Carneskog, Inge Høgh Dufva, L. Vilén, Hans Wadenvik, Ulf-Henrik Mellqvist, Hans Wedel, Jack Kutti

المصدر: European Journal of Haematology. 65:267-271

مصطلحات موضوعية: education.field_of_study, medicine.medical_specialty, Pediatrics, business.industry, Incidence (epidemiology), Population, Retrospective cohort study, Hematology, General Medicine, medicine.disease, Chronic myeloproliferative disorders, Epidemiology, medicine, European standard, education, Myelofibrosis, business, Case analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b0ea0a22937ceb28c471b2433c09c547
https://doi.org/10.1034/j.1600-0609.2000.065004267.x

المؤلفون: K Brøndum-Nielsen, Hans Karle, H O Madsen, Hans Erik Johnsen, Inge Høgh Dufva, Maria Andersen

المصدر: Leukemia. 19:671-673

مصطلحات موضوعية: Cancer Research, business.industry, Complete remission, Hematology, Imatinib therapy, Chronic myeloid leukaemia, Fusion gene, Transformation (genetics), Remission induction, Oncology, hemic and lymphatic diseases, Immunology, Cancer research, Medicine, Leukocytosis, medicine.symptom, NODAL, business, neoplasms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9da50b339872a2108d3e9902f53ecc5a
https://doi.org/10.1038/sj.leu.2403662

المؤلفون: Ulla Olsson-Strömberg, Inge Høgh Dufva, Anna-Maria Andersson, Kimmo Porkka, Ole Weis Bjerrum, Katrine Bay

المصدر: Andrology-Open Access.

مصطلحات موضوعية: medicine.medical_specialty, Leydig cell, biology, business.industry, Myeloid leukemia, Imatinib, General Medicine, medicine.disease, Follicle-stimulating hormone, medicine.anatomical_structure, Endocrinology, Sex hormone-binding globulin, Gynecomastia, hemic and lymphatic diseases, Internal medicine, medicine, biology.protein, Luteinizing hormone, business, Testosterone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b14bb48aa51a87a12b55a810797948a1
https://doi.org/10.4172/2167-0250.1000105

المؤلفون: Andreas Hochhaus, Stephane Morisset, Charles Chuah, Grzegorz W. Basak, Sandrine Hayette, Mauricette Michallet, Martin C. Müller, Inge Høgh Dufva, Senaka Peter, Gabriel Etienne, Giuseppe Saglio, Giovanni Martinelli, Franck E. Nicolini, Hélène Labussière, Wei Zhou, Simona Soverini, Jorge E. Cortes, Giovanna Rege-Cambrin, Michael J. Mauro, Eduardo Olavarria, Jane F. Apperley

المساهمون: Nicolini F.E., Basak G.W., Soverini S., Martinelli G., Mauro M.J., Müller M.C., Hochhaus A., Chuah C., Dufva I.H., Rege-Cambrin G., Saglio G., Michallet M., Labussière H., Morisset S., Hayette S., Etienne G., Olavarria E., Zhou W., Peter S., Apperley J.F., Cortes J.

مصطلحات موضوعية: Oncology, Male, Clinical Trials and Observations, medicine.medical_treatment, bcr-abl, Fusion Proteins, bcr-abl, Drug Resistance, Graft vs Host Disease, Hematopoietic stem cell transplantation, Adolescent, Adult, Aged, Drug Resistance, Neoplasm, Female, Follow-Up Studies, Hematopoietic Stem Cell Transplantation, Humans, Middle Aged, Prognosis, Registries, Transplantation, Homologous, Young Adult, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematology, Biochemistry, Cell Biology, Immunology, hemic and lymphatic diseases, Medicine, Chronic, Leukemia, Hazard ratio, Myeloid leukemia, Stem cell, Tyrosine kinase, Homologous, medicine.medical_specialty, Myelogenous, Internal medicine, Transplantation, business.industry, Fusion Proteins, medicine.disease, Neoplasm, BCR-ABL Positive, business

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9be51553aa173c2a9a27062c783f63b
http://hdl.handle.net/2318/157518

المؤلفون: Malene, Risum, Inge Høgh, Dufva

المصدر: Ugeskrift for laeger. 172(6)

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Leukemia, Myeloid, Acute, Risk Factors, Tumor Necrosis Factor-alpha, Myelodysplastic Syndromes, Humans, Antineoplastic Agents, Prognosis, Lenalidomide, Thalidomide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::17a4de79719be30fd1d992b60d418e17
https://pubmed.ncbi.nlm.nih.gov/20146910

المؤلفون: Franck E. Nicolini, John M. Goldman, Cesar Sanz Rodriguez, Inge Høgh Dufva, Jay D. Pearson, Senaka Peter, Jorge E. Cortes, Claude Preudhomme, Fumiharu Yagasaki, Andreas Hochhaus, Simona Soverini, Dong-Wook Kim, Martin C. Müller, Michael J. Mauro, Charles Chuah, Jane F. Apperley, Francis J. Giles, Giovanni Martinelli, Wei Zhou

المساهمون: Nicolini FE, Mauro MJ, Martinelli G, Kim DW, Soverini S, Muller MC, Hochhaus A, Cortes J, Chuah C, Dufva IH, Apperley JF, Yagasaki F, Pearson JD, Peter S, Sanz Rodriguez C, Preudhomme C, Giles F, Goldman JM, Zhou W.

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Adolescent, Clinical Trials and Observations, Immunology, Kaplan-Meier Estimate, Genes, abl, Biology, Philadelphia chromosome, Biochemistry, Disease-Free Survival, Young Adult, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Internal medicine, hemic and lymphatic diseases, medicine, Humans, Aged, Retrospective Studies, Aged, 80 and over, CHRONIC MYELOID LEUKEMIA, Hematology, T315I MUTATION, ACUTE LYMPHOBLASTIC LEUKEMIA, Myeloid leukemia, Imatinib, Cell Biology, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Transplantation, Leukemia, Drug Resistance, Neoplasm, Mutation, Cancer research, Cytarabine, Female, medicine.drug, Chronic myelogenous leukemia

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ffb45af214242a01b7527550eab469
http://hdl.handle.net/11585/82907

المؤلفون: Hans Carl, Hasselbalch, Henrik, Birgens, Inge Høgh, Dufva, Anne-Marie, Dalseg, Peter de Nully, Brown, Morten Krogh, Jensen, Anette, Vangsted

المصدر: Ugeskrift for laeger. 170(24)

مصطلحات موضوعية: Anemia, Hemolytic, Indoles, Lymphoma, Recombinant Fusion Proteins, Carbazoles, Dasatinib, Antineoplastic Agents, Receptors, Fc, Antibodies, Monoclonal, Humanized, Benzoates, Piperazines, Bortezomib, Antibodies, Monoclonal, Murine-Derived, Humans, Immunologic Factors, Furans, Cyclophosphamide, Lenalidomide, Leukemia, Antibodies, Monoclonal, Boronic Acids, Gemtuzumab, Hematologic Diseases, Leukemia, Lymphocytic, Chronic, B-Cell, Thalidomide, Leukemia, Myeloid, Acute, Thiazoles, Aminoglycosides, Hydrazines, Pyrimidines, Purpura, Thrombocytopenic, Thrombopoietin, Myelodysplastic Syndromes, Pyrazines, Benzamides, Imatinib Mesylate, Pyrazoles, Carrier Proteins, Multiple Myeloma, Rituximab, Vidarabine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e0a657c25ec02eca8da931c159e5321a
https://pubmed.ncbi.nlm.nih.gov/18565291

المؤلفون: Ole Weis, Bjerrum, Inge Høgh, Dufva, Jesper, Stentoft, Hans Carl, Hasselbalch

المصدر: Ugeskrift for laeger. 170(5)

مصطلحات موضوعية: Thiazoles, Pyrimidines, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Dasatinib, Humans, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::13eaa62309a5cee3ef073b6fed0153ea
https://pubmed.ncbi.nlm.nih.gov/18252160

المؤلفون: P. Watson, Giovanni Martinelli, Philippe Rousselot, Timothy P. Hughes, Francis J. Giles, Mahon Fx, Inge Høgh Dufva, Cristina Papayannidis, John F. Seymour, Arnon Nagler, A. Haregewoin, Jorge E. Cortes, Eric J. Rubin, Dong-Wook Kim, Jason Clark, J. L. Jimenez

المساهمون: Seymour, J.F, Kim, D.W., Rubin, E., Haregewoin, A., Clark, J., Watson, P., Hughes, T., Dufva, I., Jimenez, J.L., Mahon, F.-X., Rousselot, P., Cortes, J., Martinelli, G., Papayannidis, C., Nagler, A., Giles, F.J.

المصدر: Blood Cancer Journal

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Fusion Proteins, bcr-abl, Mutation, Missense, Philadelphia chromosome, Gastroenterology, Piperazines, Myelogenous, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Philadelphia Chromosome, Protein Kinase Inhibitors, Aged, ABL, business.industry, Hematology, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Hematologic Response, Leukemia, Amino Acid Substitution, Oncology, Immunology, Female, Original Article, business, Complete Hematologic Response, Febrile neutropenia, Chronic myelogenous leukemia

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d779a6ba9e8994bcd2ef48839f7980f
https://doi.org/10.1038/bcj.2014.60