المؤلفون: WonJin Kim, GeunHyung Kim

المصدر: Bioactive Materials, Vol 35, Iss , Pp 382-400 (2024)

مصطلحات موضوعية: Bioprinting, In situ electric field, Minispheroids, In vitro liver-tissue model, Hepatic lobule, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24000458; https://doaj.org/toc/2452-199X

URL الوصول: https://doaj.org/article/8b25651ce6e9492d96667a8a9f253ccc

المؤلفون: Lena Seidemann, Sarah Prinz, Jan-Constantin Scherbel, Christina Götz, Daniel Seehofer, Georg Damm

المصدر: EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 12-34 (2023)

مصطلحات موضوعية: in vitro liver models, primary human hepatocytes, extracellular matrix, collagen, matrigel, sandwich culture, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.excli.de/index.php/excli/article/view/5459; https://doaj.org/toc/1611-2156

URL الوصول: https://doaj.org/article/5f95ff161ca144f4a00a505c7521d57a

المؤلفون: Samantha V. Llewellyn, Gillian E. Conway, Ilaria Zanoni, Amalie Kofoed Jørgensen, Ume-Kulsoom Shah, Didem Ag Seleci, Johannes G. Keller, Jeong Won Kim, Wendel Wohlleben, Keld Alstrup Jensen, Anna Costa, Gareth J. S. Jenkins, Martin J. D. Clift, Shareen H. Doak

المصدر: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-24 (2021)

مصطلحات موضوعية: In vitro liver models, Engineered nanomaterials, Physiologically relevant exposure, Nanotoxicology, Genotoxicity, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1477-3155

URL الوصول: https://doaj.org/article/a7986442632e40378669f55646113773

المؤلفون: Serras, Ana S., Rodrigues, Joana S., Cipriano, Madalena, Rodrigues, Armanda V., Oliveira, Nuno G, Miranda, Joana P

مصطلحات موضوعية: in vitro liver model, fit-for-purpose models, hepatotoxicity, paracetamol, diclofenac, troglitazone, three-dimensional culture

Relation: info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FMED-TOX%2F29183%2F2017/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04138%2F2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FDTP%2F04138%2F2013/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04138%2F2020/PT; info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F144130%2F2019/PT; GA-845147-LIV-AD-ON-A-CHIP; TUBITAK/003/2014; https://www.frontiersin.org/articles/10.3389/fcell.2021.626805; Serras AS, Rodrigues JS, Cipriano M, Rodrigues AV, Oliveira NG, Miranda JP. A critical perspective on 3d liver models for drug metabolism and toxicology studies. Frontiers in Cell and Developmental Biology [Internet]. 2021;9:626805. Disponível em: https://www.frontiersin.org/article/10.3389/fcell.2021.626805; http://hdl.handle.net/10451/52314; cv-prod-2244360; https://doi.org/10.3389/fcell.2021.626805

الاتاحة: http://hdl.handle.net/10451/52314
https://doi.org/10.3389/fcell.2021.626805

المؤلفون: Jun Sang Yu (6599615), Louis-Félix Nothias (3236412), Mingxun Wang (1327497), Dong Hyun Kim (184121), Pieter C. Dorrestein (224907), Kyo Bin Kang (3096351), Hye Hyun Yoo (1838857)

مصطلحات موضوعية: Biochemistry, Genetics, Pharmacology, Biotechnology, Sociology, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vitro liver microsome, untargeted mass spectrometry, ms )/ ms, mass defect filtering, drug metabolite identification, drug metabolism studies, 27 known metabolites, 25 unknown metabolites, based metabolism study, detected metabolites, annotate metabolites, based postprocessing, based metabolomics, sildenafil generated, provided evidence, human labor, false positives, existing tools, existing strategies, effort required, efficient tool

Relation: https://figshare.com/articles/journal_contribution/Tandem_Mass_Spectrometry_Molecular_Networking_as_a_Powerful_and_Efficient_Tool_for_Drug_Metabolism_Studies/17894641

الاتاحة: https://doi.org/10.1021/acs.analchem.1c04925.s001

المؤلفون: Fang-Chun Liao, Yang-Kao Wang, Ming-Yang Cheng, Ting-Yuan Tu

المصدر: Polymers; Volume 14; Issue 9; Pages: 1923

مصطلحات موضوعية: HepaRG, 3D culture, spheroid, recombinant human collagen, in vitro liver model

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/polym14091923

الاتاحة: https://doi.org/10.3390/polym14091923

المؤلفون: Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian

المصدر: Gupta , R , Schrooders , Y , Hauser , D , van Herwijnen , M , Albrecht , W , ter Braak , B , Brecklinghaus , T , Castell , J V , Elenschneider , L , Escher , S , Guye , P , Hengstler , J G , Ghallab , A , Hansen , T , Leist , M , Maclennan , R , Moritz , W , Tolosa , L , Tricot , T , Verfaillie , C , Walker , P , van de Water , B , Kleinjans , J & Caiment ....

مصطلحات موضوعية: In vivo liver, In vitro liver, RNA-seq, CellNet, Non-DEGs, Non-DEGs(DTU), Pathway coverage, HEPARG CELLS, PRIMARY HEPATOCYTES, TOXICITY, DIFFERENTIATION, HEPATOTOXICITY, METABOLISM, INDUCTION, EVOLUTION, PLATFORM, SYSTEMS

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/c38fbec6-8055-4885-8173-d124c9970c62
https://doi.org/10.1007/s00204-020-02937-6

المؤلفون: Samantha V. Llewellyn (11039855), Gillian E. Conway (11039858), Ilaria Zanoni (11039861), Amalie Kofoed Jørgensen (11039864), Ume-Kulsoom Shah (11039867), Didem Ag Seleci (742346), Johannes G. Keller (9563743), Jeong Won Kim (796906), Wendel Wohlleben (1416550), Keld Alstrup Jensen (806562), Anna Costa (332124), Gareth J. S. Jenkins (3897589), Martin J. D. Clift (11039870), Shareen H. Doak (7164620)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Physiology, Pharmacology, Biotechnology, Ecology, Immunology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, In vitro liver models, Engineered nanomaterials, Physiologically relevant exposure, Nanotoxicology, Genotoxicity

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Understanding_the_impact_of_more_realistic_low-dose_prolonged_engineered_nanomaterial_exposure_on_genotoxicity_using_3D_models_of_the_human_liver/14870570

الاتاحة: https://doi.org/10.6084/m9.figshare.14870570.v1

المؤلفون: Alycia Abbott (5613725), Jeannine M. Coburn (8039474)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Ecology, Developmental Biology, Plant Biology, Computational Biology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, hepatic progenitor cells, Silk Fibroin Scaffolds, silk scaffolds, albumin secretion, scaffolded HepaRG cells, culture, RGD, Vitro Liver Model, lipid droplet accumulation, support HepaRG growth, ECM, HepaRG cell attachment, 14 days, liver cell growth, HepaRG cells, influence CYP 3A expression

Relation: https://figshare.com/articles/journal_contribution/HepaRG_Maturation_in_Silk_Fibroin_Scaffolds_Toward_Developing_a_3D_i_In_Vitro_i_Liver_Model/14755237

الاتاحة: https://doi.org/10.1021/acsbiomaterials.0c01584.s001

المؤلفون: Liza Dewyse, Hendrik Reynaert, Leo A. van Grunsven

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 13; Pages: 7137

مصطلحات موضوعية: PCLS, chronic liver disease, 3D, in vitro liver

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms22137137

الاتاحة: https://doi.org/10.3390/ijms22137137

المؤلفون: Andrea Zimmermann, René Hänsel, Kilian Gemünden, Victoria Kegel-Hübner, Jonas Babel, Hendrik Bläker, Madlen Matz-Soja, Daniel Seehofer, Georg Damm

المصدر: Biomedicines; Volume 9; Issue 4; Pages: 406

مصطلحات موضوعية: human liver, liver cell isolation, primary human liver cells, hepatic macrophages, Kupffer cells, monocyte-derived macrophages, macrophage heterogeneity, inflammatory liver diseases, in vitro liver model

وصف الملف: application/pdf

Relation: Immunology and Immunotherapy; https://dx.doi.org/10.3390/biomedicines9040406

الاتاحة: https://doi.org/10.3390/biomedicines9040406

المؤلفون: Georgia-Persephoni Voulgaridou, Theodora Mantso, Ioannis Anestopoulos, Ariel Klavaris, Christina Katzastra, Despoina-Eugenia Kiousi, Marini Mantela, Alex Galanis, Konstantinos Gardikis, Ibrahim M. Banat, Tony Gutierrez, Karina Sałek, Stephen Euston, Mihalis I. Panayiotidis, Aglaia Pappa

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 5; Pages: 2383

مصطلحات موضوعية: surface active agents, marine biosurfactants, toxicity profiling, antioxidant activity, anti-mutagenic activity, cytotoxicity, Marinobacter strains, Pseudomonas strains, in vitro skin model, in vitro liver model

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Role of Xenobiotics; https://dx.doi.org/10.3390/ijms22052383

الاتاحة: https://doi.org/10.3390/ijms22052383

المؤلفون: Noorlander, Annelies, Lautz, Leonie, Holleboom, Wendy Janssen, Mulder, Patrick P.J., Stoopen, Geert, Punt, Ans

المصدر: EFSA supporting publication, EN-8820, 92, (2024-07-25)

مصطلحات موضوعية: in vitro liver metabolism, liver S9, Integrated Approaches to Testing and Assessment (IATA), Physiologically based kinetic (PBK) modelling, risk assessment, allylalkoxybenzenes, species differences

Relation: https://doi.org/10.2903/sp.efsa.2024.EN-8820; https://zenodo.org/communities/efsa-kj; https://doi.org/10.5281/zenodo.12513914; https://doi.org/10.5281/zenodo.12513915; oai:zenodo.org:12513915

الاتاحة: https://doi.org/10.5281/zenodo.12513915

المؤلفون: Guillouzo, André

المصدر: Environmental Health Perspectives, 1998 Apr 01. 106, 511-532.

URL الوصول: https://www.jstor.org/stable/3433803

المؤلفون: Mazur, H., Merlavsky, V., Manko, B.O., Manko, V.V.

المصدر: Visnyk of Lviv University. Biological series; № 82 (2020): Випуск 82; 177-185 ; Вісник Львівського університету. Серія біологічна; № 82 (2020): Випуск 82; 177-185 ; 2075-5236 ; 0206-5657 ; 10.30970/vlubs.2020.82

مصطلحات موضوعية: the adaptive capacity of mitochondria, in situ liver perfusion, in vitro liver perfusion, hepatocytes, FCCP, адаптаційна здатність мітохондрій, перфузія печінки in situ, перфузія печінки in vitro, гепатоцити

وصف الملف: application/pdf

Relation: http://publications.lnu.edu.ua/bulletins/index.php/biology/article/view/11013/11282; http://publications.lnu.edu.ua/bulletins/index.php/biology/article/view/11013

الاتاحة: http://publications.lnu.edu.ua/bulletins/index.php/biology/article/view/11013
https://doi.org/10.30970/vlubs.2020.82.16

المؤلفون: Seidemann, Lena, Prinz, Sarah, Scherbel, Jan-Constantin, Götz, Christina, Seehofer, Daniel, Damm, Georg

مصطلحات موضوعية: primary human hepatocytes, collagen, Matrigel, extracellular matrix, in vitro liver models, sandwich culture

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bc6f307eb43d3df8fc1236ea0f397f

المؤلفون: Coll, Mar, Perea, Luis, Boon, Ruben, Leite, Sofia B, Vallverdú, Julia, Mannaerts, Inge, Smout, Ayla, El Taghdouini, Adil, Blaya, Delia, Rodrigo-Torres, Daniel, Graupera, Isabel, Aguilar-Bravo, Beatriz, Chesne, Christophe, Najimi, Mustapha, Sokal, Etienne, Lozano, Juan José, van Grunsven, Leo A, Verfaillie, Catherine M, Sancho-Bru, Pau

المساهمون: UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique

المصدر: Cell stem cell, Vol. 23, no.1, p. 101-113.e7 (2018)

مصطلحات موضوعية: Cell Differentiation, Cells, Cultured, Coculture Techniques, Female, Hepatic Stellate Cells, Humans, Infant, Newborn, Liver Cirrhosis, Male, Models, Biological, Pluripotent Stem Cells, Thioacetamide, Wound Healing, differentiation, disease modeling, in vitro liver model, liver fibrosis, liver spheroids, non-parenchymal cells, organoids, toxicity assessment

Relation: boreal:232108; http://hdl.handle.net/2078.1/232108; info:pmid/30049452; urn:ISSN:1934-5909; urn:EISSN:1875-9777

الاتاحة: http://hdl.handle.net/2078.1/232108
https://doi.org/10.1016/j.stem.2018.05.027

المؤلفون: Anna Luisa Costa, Johannes Keller, Wendel Wohlleben, Gareth J.S. Jenkins, Ume-Kulsoom Shah, Jeong Won Kim, Keld Alstrup Jensen, Samantha V. Llewellyn, Martin J. D. Clift, Didem Ag Seleci, Shareen H. Doak, Gillian E. Conway, Amalie Kofoed Jørgensen, Ilaria Zanoni

المصدر: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-24 (2021)
Journal of Nanobiotechnology

مصطلحات موضوعية: Engineered nanomaterials, DNA damage, Biomedical Engineering, Medicine (miscellaneous), Pharmaceutical Science, Bioengineering, 02 engineering and technology, Pharmacology, medicine.disease_cause, Applied Microbiology and Biotechnology, 03 medical and health sciences, In vivo, Albumins, In vitro liver models, Medical technology, Humans, Urea, Medicine, Particle Size, R855-855.5, Cytotoxicity, Nanotoxicology, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Mutagenicity Tests, business.industry, Research, Albumin, Hep G2 Cells, 021001 nanoscience & nanotechnology, Nanostructures, Liver, Toxicity, Cytokines, Molecular Medicine, Bolus (digestion), Genotoxicity, 0210 nano-technology, business, Hydrophobic and Hydrophilic Interactions, Physiologically relevant exposure, TP248.13-248.65, DNA Damage, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b53c9862987c5b53aa9fd3c93d886c
https://doaj.org/article/a7986442632e40378669f55646113773

المؤلفون: Akihito Tsubota, Akira Koibuchi, Atsuko Kamiichi, Hanae Morio, Hidetaka Akita, Hideyuki Ide, Kan Chiba, Meiyan Zhu, Minaka Shibuya, Naohiko Anzai, Tomomi Furihata

المصدر: Biological and Pharmaceutical Bulletin. 2018, 41(3):440

المؤلفون: Verma, Poonam, Verma, Vipin, Ray, Pratima, Ray, Alok R.

المصدر: In Vitro Cellular & Developmental Biology. Animal, 2007 Nov 01. 43(10), 328-337.

URL الوصول: https://www.jstor.org/stable/40205830