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المؤلفون: Hassan, Amel, Lee, Pamela, Maggina, Paraskevi, Xu, Jin Hua, Moreira, Diana, Slatter, Mary, Nademi, Zohreh, Worth, Austen, Adams, Stuart, Jones, Alison, Cale, Catherine, Allwood, Zoe, Rao, Kanchan, Chiesa, Robert, Amrolia, Persis, Gaspar, Hubert, Davies, E. Graham, Veys, Paul, Gennery, Andrew, Qasim, Waseem
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Male, Transplantation Conditioning, MSD, Matched sibling donor, Immunology, allo-SCT, Allogeneic hematopoietic stem cell transplantation, Article, conditioning, T-Lymphocyte Subsets, Immune Deficiencies, Infection, and Systemic Immune Disorders, NK, Natural killer, Immunology and Allergy, Humans, Transplantation, Homologous, Cell Lineage, SCID, Severe combined immunodeficiency, MFD, Matched family donor, Transplantation Chimera, natural killer cells, Graft Survival, TREC, T-cell receptor excision circle, Hematopoietic Stem Cell Transplantation, Infant, Newborn, Infant, adenosine deaminase deficiency, ADA, Adenosine deaminase deficiency, JAK3, Janus kinase 3, Killer Cells, Natural, Severe combined immunodeficiency, chimerism, Female, engraftment
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2
المؤلفون: Calman A. MacLennan, Wilson L. Mandala, Esther N. Gondwe, Jenny M. MacLennan, Malcolm E. Molyneux, Steven A. Ward
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Male, Malawi, Lymphocyte, Physiology, HIV Infections, 0302 clinical medicine, T-Lymphocyte Subsets, NK, Natural killer, Immunology and Allergy, Medicine, 030212 general & internal medicine, Young adult, Child, Sida, Immunodeficiency, Aged, 80 and over, 0303 health sciences, education.field_of_study, biology, Middle Aged, 3. Good health, AIDS, medicine.anatomical_structure, Child, Preschool, Female, Adult, Adolescent, Lymphocyte subsets, Immunology, Population, B-Lymphocyte Subsets, WHO, World Health Organization, Young Adult, 03 medical and health sciences, immunophenotyping, Acquired immunodeficiency syndrome (AIDS), Immune Deficiencies, Infection, and Systemic Immune Disorders, Humans, education, Aged, 030304 developmental biology, business.industry, flow cytometry, Infant, Newborn, Infant, CD4 lymphocyte count, HIV, T lymphocyte, biology.organism_classification, medicine.disease, Africa, ART, Antiretroviral therapy, business
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3
المؤلفون: Cetica, Valentina, Hackmann, Yvonne, Grieve, Samantha, Sieni, Elena, Ciambotti, Benedetta, Coniglio, Maria Luisa, Pende, Daniela, Gilmour, Kimberly, Romagnoli, Paolo, Griffiths, Gillian M., Aricò, Maurizio
المساهمون: Griffiths, Gillian [0000-0003-0434-5842], Apollo - University of Cambridge Repository
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Cytotoxicity, Immunologic, Genetic Markers, Male, Models, Molecular, endocrine system, Adolescent, Albinism, Protein Conformation, CTL, Cytotoxic T lymphocyte, Immunology, DNA Mutational Analysis, Slp2a, Synaptotagmin-like protein 2a, Gene Expression, Skin Pigmentation, Hemophagocytic lymphohistiocytosis, cytotoxic T lymphocyte, Cell Degranulation, Lymphohistiocytosis, Hemophagocytic, rab27 GTP-Binding Proteins, Cell Line, Cohort Studies, Immune Deficiencies, Infection, and Systemic Immune Disorders, NK, Natural killer, Immunology and Allergy, GRA, Granule release assay, Humans, Child, Mlph, melanophilin, Adaptor Proteins, Signal Transducing, natural killer cells, Perforin, familial hemophagocytic lymphohistiocytosis, Infant, Membrane Proteins, Griscelli syndrome type 2, FHL, Familial Hemophagocytic lymphohistiocytosis, HLH, Hemophagocytic lymphohistiocytosis, melanophilin, Phenotype, rab GTP-Binding Proteins, Case-Control Studies, Child, Preschool, GFP, Green fluorescent protein, Mutation, Female, GS2, Griscelli syndrome type 2, GTP, Guanosine triphosphate, OMIM, Online Mendelian Inheritance in Man, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Jacek Majewski, Nada Jabado, Marina Cavazzana, Alain Fischer, Jeremy Schwartzentruber, Anne Durandy, Monique Forveille, Michel C. Nussenzweig, Sven Kracker, Necil Kutukculer, Cyrille Cuenin, Anna Gazumyan, Kevin M. McBride, Suranjith L. Seneviratne, Michela Di Virgilio, Zdenko Herceg, Bodo Grimbacher, Marie Céline Deau
المساهمون: Ege Üniversitesi
المصدر: Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunologyمصطلحات موضوعية: Cancer Research, DNA Repair, Chromosomal Proteins, Non-Histone, cohesin, Cell Cycle Proteins, DAPI, 4′,6-Diamidino-2-phenylindole, Immunoglobulin Switch Region, 0302 clinical medicine, ChIP, Chromatin immunoprecipitation, Activation-induced (cytidine) deaminase, AID, Activation-induced cytidine deaminase, Immunology and Allergy, CSR, Class-switch recombination, Gene Rearrangement, 0303 health sciences, 3. Good health, Raji cell, DNA-Binding Proteins, Immunoglobulin Isotypes, Protein Transport, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Protein Binding, Cell Survival, Immunology, CSR-Ds, CSR defects, chemical and pharmacologic phenomena, Biology, Models, Biological, Immunoglobulin Class Switch Recombination, Cell Line, Chromatin remodeling, class-switch recombination defect, 03 medical and health sciences, Immune Deficiencies, Infection, and Systemic Immune Disorders, medicine, GLT, Germ-line transcript, Humans, B cell, 030304 developmental biology, Cohesin, DNA Helicases, Immunologic Deficiency Syndromes, wt, Wild type, Genetic Variation, Gene rearrangement, NHEJ, Non-homologous end joining, Chromatin Assembly and Disassembly, Molecular biology, Immunoglobulin Class Switching, Immunoglobulin class switching, Gene Expression Regulation, TCR, T-cell receptor, CSR synapse, biology.protein, MMR, Mismatch repair, ATPases Associated with Diverse Cellular Activities, Carrier Proteins
وصف الملف: application/pdf
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المؤلفون: Kinga K, Smolen, Candice E, Ruck, Edgardo S, Fortuno, Kevin, Ho, Pedro, Dimitriu, William W, Mohn, David P, Speert, Philip J, Cooper, Monika, Esser, Tessa, Goetghebuer, Arnaud, Marchant, Tobias R, Kollmann
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Innate immunity, PGN, Peptidoglycan, infectious disease, Toll-Like Receptors, PCA, Principal-component analysis, Infant, PRR, Pattern-recognition receptor, Infections, global, Immunity, Innate, MDP, Muramyl dipeptide, Immune Deficiencies, Infection, and Systemic Immune Disorders, immune development, Child, Preschool, Receptors, Pattern Recognition, Infant Mortality, NOD, Nucleotide-binding oligomerization domain-containing protein, Cytokines, Humans, R848, Resiquimod, Disease Susceptibility, Poly I:C, Polyinosinic-polycytidylic acid, LPS, Lipopolysaccharide, TLR, Toll-like receptor
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المؤلفون: Chen, H, Handel, Ngeow, Huhn, Yang, Heindl, Berbers, Hegazy, A, Kionke, Yehia, Sack, Blaser, Rensing-Ehl, Reifenberger, Keith, J, Travis, S, Merkenschlager, Keiss, Wittekind, Walker, L, Ehl, Aretz, Dustin, Eng, Powrie, F, Uhlig, H
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Male, PTEN, Immunological Synapses, TMRE, Tetramethylrhodamine-ethylester, T-Lymphocytes, Regulatory, SHIP, Src homology domain 2–containing inositol phosphatase, CS, Cowden syndrome, PI3K, Phosphoinositide 3-kinase, Phosphoprotein Phosphatases, Immunology and Allergy, phosphatases, Child, Cells, Cultured, MALT, Mucosa-associated lymphoid tissue, Membrane Potential, Mitochondrial, B-Lymphocytes, autoimmunity, phosphoinositide 3-kinase, Nuclear Proteins, PHLPP, PH domain leucine-rich repeat protein phosphatase, Forkhead Transcription Factors, POD, Peroxidase, Regulatory T cells, Middle Aged, IC50, Inhibitory concentration of 50%, FACS, Fluorescence-activated cell sorting, FOXP3, Forkhead box P3, Protein Transport, CTLA-4, Cytotoxic T lymphocyte–associated antigen 4, Protein Binding, Signal Transduction, Adult, FITC, Fluorescein isothiocyanate, PH domain leucine-rich repeat protein phosphatase, HRM, High Resolution DNA Melting, Adolescent, APC, Allophycocyanin, ICAM-1, Intercellular adhesion molecule 1, Immunology, NHERF1, Na+/H+-exchanger 3 regulatory factor, chemical and pharmacologic phenomena, mTORC1, PTEN/AKT/mTOR complex 1, DLG1, Scaffold protein discs, large homolog 1, PerCP, Peridinin-chlorophyll-protein complex, PP2A, Protein phosphatase 2A, immunologic synapse, Young Adult, Immune Deficiencies, Infection, and Systemic Immune Disorders, Humans, Aged, PTEN, Phosphatase and tensin homologue deleted on chromosome 10, Hyperplasia, PTEN Phosphohydrolase, mTOR, Mammalian target of rapamycin, PE, Phycoerythrin, PHTS, PTEN hamartoma tumor syndrome, Lymphocyte Subsets, TCR, T-cell receptor, Tmem, Memory T, iTreg, In vitro induced regulatory T, Mutation, PHTS, Hamartoma Syndrome, Multiple
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المؤلفون: Coulter, TI, Chandra, A, Bacon, CM, Babar, J, Curtis, J, Screaton, N, Goodlad, JR, Farmer, G, Steele, CL, Leahy, TR, Doffinger, R, Baxendale, H, Bernatoniene, J, Edgar, JD, Longhurst, HJ, Ehl, S, Speckmann, C, Grimbacher, B, Sediva, A, Milota, T, Faust, SN, Williams, AP, Hayman, G, Kucuk, ZY, Hague, R, French, P, Brooker, R, Forsyth, P, Herriot, R, Cancrini, C, Palma, P, Ariganello, P, Conlon, N, Feighery, C, Gavin, PJ, Jones, A, Imai, K, Ibrahim, MA, Markelj, G, Abinun, M, Rieux-Laucat, F, Latour, S, Pellier, I, Fischer, A, Touzot, F, Casanova, JL, Durandy, A, Burns, SO, Savic, S, Kumararatne, DS, Moshous, D, Kracker, S, Vanhaesebroeck, B, Okkenhaug, K, Picard, C, Nejentsev, S, Condliffe, AM, Cant, AJ
المساهمون: Chandra, Anita [0000-0002-9061-879X], Okkenhaug, Klaus [0000-0002-9432-4051], Nezhentsev, Sergey [0000-0002-7528-4461], Apollo - University of Cambridge Repository
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Adult, Male, Adolescent, bronchiectasis, Class I Phosphatidylinositol 3-Kinases, International Cooperation, Immunology, PPV, Pneumococcal polysaccharide vaccine, HSCT, Hematopoietic stem cell transplantation, Cohort Studies, Mice, Young Adult, APDS, Activated phosphoinositide-3 kinase δ syndrome, phosphoinositide 3-kinase inhibitor, Immune Deficiencies, Infection, and Systemic Immune Disorders, Recurrence, PI3K, Phosphoinositide 3-kinase, Surveys and Questionnaires, BALF, Bronchoalveolar lavage fluid, Activated phosphoinositide 3-kinase δ syndrome, Animals, Humans, Immunology and Allergy, Enzyme Inhibitors, CMV, Cytomegalovirus, Child, HSV, Herpes simplex virus, Respiratory Tract Infections, CNS, Central nervous system, Hematopoietic Stem Cell Transplantation, Immunologic Deficiency Syndromes, Immunoglobulins, Intravenous, Infant, GOF, Gain of function, Herpesviridae Infections, Antibiotic Prophylaxis, Middle Aged, PIK3CD gene, Survival Analysis, Lymphoproliferative Disorders, Child, Preschool, Mutation, CT, Computed tomography, p110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency, Female, immunodeficiency, phosphoinositide 3-kinase δ, OR, Odds ratio
وصف الملف: application/pdf
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المؤلفون: Stefanie Scheu, Tak W. Mak, Stephanie Borkens, Gerben Bouma, Dieter Häussinger, Philipp A. Lang, Nadine Honke, Adrian J. Thrasher, Namir Shaabani, Carmen Barthuber, Sarah Booth, Andreas Meryk, Mike Recher, Dirk Brenner, Gillian M. Griffiths, Karl S. Lang, Pamela S. Ohashi
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: pfu, Plaque-forming units, Medizin, pDC, Plasmacytoid dendritic cell, Plasmacytoid dendritic cell, CD8-Positive T-Lymphocytes, cDC, Conventional dendritic cell, Mice, 0302 clinical medicine, NK, Natural killer, Interferon, Lymphocytic choriomeningitis virus, Immunology and Allergy, Immunodeficiency, Mice, Knockout, Wiskott-Aldrich syndrome protein, 0303 health sciences, diabetes, biology, Wiskott-Aldrich syndrome, Wiskott–Aldrich syndrome protein, IL-7R, IL-7 receptor, WASP, Wiskott-Aldrich syndrome protein, DC, Dendritic cell, FACS, Fluorescence-activated cell sorting, LCMV, Lymphocytic choriomeningitis virus, 3. Good health, WAS KO, WASP knockout, Interferon Type I, TLR, Toll-like receptor, medicine.drug, Immunology, CD8 T cells, virus, macromolecular substances, Lymphocytic choriomeningitis, Vesicular stomatitis Indiana virus, 03 medical and health sciences, Immune system, Immune Deficiencies, Infection, and Systemic Immune Disorders, YFP, Yellow fluorescent protein, Rhabdoviridae Infections, medicine, Animals, Arenaviridae Infections, Humans, dendritic cells, Type I interferon, 030304 developmental biology, IFN-I, Type I interferon, Poly(I:C), Polyinosine-polycytidylic acid, medicine.disease, Type I interferon production, Virology, Mice, Inbred C57BL, Disease Models, Animal, WAS, Wiskott-Aldrich syndrome, VSV, Vesicular stomatitis virus, biology.protein, Interferon type I, 030215 immunology
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المؤلفون: Shinji Toki, Kelli L. Boyd, Anne L. Hotard, Tina V. Hartert, Marc C. Quitalig, Melissa H. Bloodworth, Baohua Zhou, Andrew N. J. McKenzie, Kasia Goleniewska, Dawn C. Newcomb, Matthew T. Stier, Martin L. Moore, R. Stokes Peebles
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, respiratory syncytial virus, PAS, Periodic acid–Schiff, 0302 clinical medicine, MFI, Mean fluorescence intensity, Immunology and Allergy, Lymphocytes, Respiratory system, Lung, TSLP, Thymic stromal lymphopoietin, Plaque-forming unit, Mice, Knockout, Mice, Inbred BALB C, Interleukin-13, Group 2 innate lymphoid cells, Innate lymphoid cell, respiratory system, Viral Load, 3. Good health, IL-13, PFU, Plaque-forming units, Interleukin 13, Cytokines, RSV, Respiratory syncytial virus, Female, INSPIRE, Infant Susceptibility to Pulmonary Infections and Asthma Following RSV Exposure, Viral load, ILC2, Group 2 innate lymphoid cell, BAL, Bronchoalveolar lavage, Thymic stromal lymphopoietin, WT, Wild-type, TSLPR, Thymic stromal lymphopoietin receptor, Immunology, Respiratory Syncytial Virus Infections, Biology, Virus, 03 medical and health sciences, thymic stromal lymphopoietin, Immune Deficiencies, Infection, and Systemic Immune Disorders, ILC, Innate lymphoid cell, Animals, type 2 immunity (TH2), KO, Knockout, Interleukin-33, Interleukin 33, Mucus, 030104 developmental biology, IL-33, 030215 immunology
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المؤلفون: Franco Locatelli, Lorenzo Moretta, Concetta Micalizzi, Valentina Cetica, Elena Sieni, Carmen De Fusco, Franca Fagioli, Cesare Danesino, Maria Caterina Putti, Maurizio Aricò, Andrea Biondi, Lucio Luzzatto, Gillian M. Griffiths, Daniela Pende
المساهمون: Griffiths, Gillian [0000-0003-0434-5842], Apollo - University of Cambridge Repository, Cetica, V, Sieni, E, Pende, D, Danesino, C, De Fusco, C, Locatelli, F, Micalizzi, C, Putti, M, Biondi, A, Fagioli, F, Moretta, L, Griffiths, G, Luzzatto, L, Aricò, M
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, Male, PRF1, Hemophagocytic, immunologic tests, Disease, Hemophagocytic lymphohistiocytosis, HSCT, Hematopoietic stem cell transplantation, FHL, Familial hemophagocytic lymphohistiocytosis, NK, Natural killer, immunologic test, Immunology and Allergy, Registries, Child, Lymphohistiocytosis, biology, Familial Hemophagocytic Lymphohistiocytosis, Middle Aged, 3. Good health, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, Italy, Child, Preschool, Female, Hemophagocytosis, Hemophagocytic lymphohistiocytosi, Adult, Adolescent, Immunology, Lymphohistiocytosis, Hemophagocytic, 03 medical and health sciences, Young Adult, XLP, X-linked lymphoproliferative syndrome, UNC13D, Humans, Infant, Infant, Newborn, Membrane Proteins, Perforin, Genetic Predisposition to Disease, Immune Deficiencies, Infection, and Systemic Immune Disorders, medicine, Genetic predisposition, Preschool, business.industry, medicine.disease, Newborn, HLH, Hemophagocytic lymphohistiocytosis, 030104 developmental biology, Macrophage activation syndrome, biology.protein, hemophagocytic lymphohistiocytosis, MAS, Macrophage activation syndrome, business
وصف الملف: application/pdf
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المؤلفون: Cooper, Philip J., Chico, Martha E., Amorim, Leila D., Sandoval, Carlos, Vaca, Maritza, Strina, Agostino, Campos, Ana Clara, Rodrigues, Laura C., Barreto, Mauricio L., Strachan, David P.
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Male, Immunology, atopy, Eczema, Helminthiasis, epg, Eggs per gram, immune system diseases, Immune Deficiencies, Infection, and Systemic Immune Disorders, Pregnancy, Risk Factors, parasitic diseases, otorhinolaryngologic diseases, Hypersensitivity, Odds Ratio, Immunology and Allergy, Animals, Humans, HDM, House dust mite, Geohelminths, Respiratory Sounds, Pyroglyphidae, Infant, Newborn, Infant, SPT, Skin prick test, early childhood, Allergens, Patient Outcome Assessment, maternal infections, Maternal Exposure, wheeze, Child, Preschool, Female, OR, Odds ratio, Follow-Up Studies
وصف الملف: application/pdf
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المؤلفون: Paolo Uva, Mirjam van der Burg, Anna Villa, Immacolata Brigida, Francesca Ferrua, Lucia Piceni Sereni, Michael H. Albert, Giorgio Ottaviano, Marita Bosticardo, Alessandro Aiuti, Maria Carmina Castiello, Francesca Pala, Maria Grazia Roncarolo, Luigi Naldini, Samantha Scaramuzza
المساهمون: Castiello, Mc, Scaramuzza, S, Pala, F, Ferrua, F, Uva, P, Brigida, I, Sereni, L, van der Burg, M, Ottaviano, G, Albert, Mh, Grazia Roncarolo, M, Naldini, Luigi, Aiuti, Alessandro, Villa, A, Bosticardo, M., Immunology
المصدر: Journal of Allergy and Clinical Immunology, 136(3), 692-+. Mosby Inc.
The Journal of Allergy and Clinical Immunologyمصطلحات موضوعية: Male, VCN, Vector copy number, Transplantation Conditioning, Wiskott–Aldrich syndrome, medicine.medical_treatment, Gene Expression, Hematopoietic stem cell transplantation, Bone Marrow, Transduction, Genetic, B-Cell Activating Factor, Immunology and Allergy, Child, BM, Bone marrow, B cell, Wiskott-Aldrich syndrome, Hematopoietic Stem Cell Transplantation, Hematopoietic stem cell, gene therapy, 3. Good health, medicine.anatomical_structure, Child, Preschool, SDF-1α, Stromal cell–derived factor 1α, Stem cell, Wiskott-Aldrich Syndrome Protein, BAFF, B cell–activating factor, Recombinant Fusion Proteins, Genetic Vectors, Immunology, B-Lymphocyte Subsets, Immunoglobulins, Biology, primary immunodeficiency, Transplantation, Autologous, CD19, Immunophenotyping, Immune Deficiencies, Infection, and Systemic Immune Disorders, WASp, Wiskott-Aldrich syndrome protein, medicine, Humans, Progenitor cell, Autoantibodies, IVIg, Intravenous immunoglobulin, GT, Gene therapy, Gene Expression Profiling, Lentivirus, lentiviral vector, Infant, PB, Peripheral blood, Genetic Therapy, HSC, Hematopoietic stem cell, Hematopoietic Stem Cells, medicine.disease, WAS, Wiskott-Aldrich syndrome, biology.protein, Bone marrow, HD, Healthy donor
وصف الملف: application/pdf