-
1
المؤلفون: Douglas W. Morgan, H. Robin Heyman, Michael R. Michaelides, Jamie R. Stacey, Patrick A. Marcotte, Yan Guo, Steven K. Davidsen, Michael L. Curtin, Carole L. Goodfellow, Joseph F. Dellaria, Daniel H. Albert, Jane Gong, James H. Holms, Terrance J. Magoc, Jennifer J. Bouska, Ildiko B. Elmore, Carol K. Wada
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:1553-1556
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Antineoplastic Agents, Ether, Matrix Metalloproteinase Inhibitors, Hydroxamic Acids, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, chemistry.chemical_compound, Pharmacokinetics, Oral administration, Drug Discovery, Animals, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Hydroxamic acid, biology, Organic Chemistry, Bioavailability, Macaca fascicularis, Enzyme, chemistry, Enzyme inhibitor, Injections, Intravenous, biology.protein, Molecular Medicine, Half-Life
-
2
المؤلفون: Terrance J. Magoc, Douglas W. Morgan, Robert B. Garland, Michael L. Curtin, Douglas H. Steinman, Yan Guo, Paul Tapang, H. Robin Heyman, Carol K. Wada, James H. Holms, Ildiko B. Elmore, Steven K. Davidsen, Joy Bauch, Alan S. Florjancic, Patrick A. Marcotte, Daniel H. Albert, Joseph F. Dellaria, Carole L. Goodfellow, Jane Gong, Jennifer J. Bouska, Michael R. Michaelides, Kennan C. Marsh
المصدر: Bioorganicmedicinal chemistry letters. 11(12)
مصطلحات موضوعية: Matrix metalloproteinase inhibitor, Stereochemistry, Metabolic Clearance Rate, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biological Availability, Antineoplastic Agents, Matrix Metalloproteinase Inhibitors, Hydroxamic Acids, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Dogs, In vivo, Oral administration, Drug Discovery, Tumor Cells, Cultured, Structure–activity relationship, Animals, Enzyme Inhibitors, Molecular Biology, Hydroxamic acid, biology, Organic Chemistry, Biphenyl Compounds, Biological activity, Haplorhini, Neoplasms, Experimental, Rats, chemistry, Enzyme inhibitor, Area Under Curve, Injections, Intravenous, biology.protein, Molecular Medicine, Cell Division, Half-Life