المؤلفون: Carol Ward, James Meehan, Mark E Gray, Alan F Murray, David J Argyle, Ian H Kunkler, Simon P Langdon

المصدر: Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 2, Pp 71-100 (2020)

مصطلحات موضوعية: tumour ph, acidosis, inhibitor, hypoxia, carbonic anhydrase ix, sodium-hydrogen exchanger 1, monocarboxylate transporter 1, monocarboxylate transporter 4, vacuolar-type h+-atpase proton pump, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.explorationpub.com/Journals/etat/Article/10025; https://doaj.org/toc/2692-3114

URL الوصول: https://doaj.org/article/433acbca338740a690220966460cdf67

المؤلفون: Mark Gray, Arran K. Turnbull, Carol Ward, James Meehan, Carlos Martínez-Pérez, Maria Bonello, Lisa Y. Pang, Simon P. Langdon, Ian H. Kunkler, Alan Murray, David Argyle

المصدر: Radiation Oncology, Vol 14, Iss 1, Pp 1-19 (2019)

مصطلحات موضوعية: Radioresistance, Breast cancer, Global gene analysis, ER and EGFR signalling, Characterisation of radioresistant cell lines, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13014-019-1268-2; https://doaj.org/toc/1748-717X

URL الوصول: https://doaj.org/article/f86ee81a892849e88ed5db0ce297194d

المؤلفون: James Meehan, Mark Gray, Carlos Martínez-Pérez, Charlene Kay, Jimi C. Wills, Ian H. Kunkler, J. Michael Dixon, Arran K. Turnbull

المصدر: Journal of Personalized Medicine; Volume 11; Issue 8; Pages: 796

مصطلحات موضوعية: breast cancer, radiotherapy, radiosensitivity biomarkers, secretome, radioresistance

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/jpm11080796

الاتاحة: https://doi.org/10.3390/jpm11080796

المؤلفون: Jamie R.K. Marland, Mark E. Gray, Camelia Dunare, Ewen O. Blair, Andreas Tsiamis, Paul Sullivan, Eva González-Fernández, Stephen N. Greenhalgh, Rachael Gregson, R. Eddie Clutton, Magdalena M. Parys, Alex Dyson, Mervyn Singer, Ian H. Kunkler, Mark A. Potter, Srinjoy Mitra, Jonathan G. Terry, Stewart Smith, Andrew R. Mount, Ian Underwood, Anthony J. Walton, David J. Argyle, Alan F. Murray

المصدر: Sensing and Bio-Sensing Research, Vol 30, Iss , Pp 100375- (2020)

مصطلحات موضوعية: Oxygen sensor, Tumour hypoxia, Implantable, Microfabrication, Engineering (General). Civil engineering (General), TA1-2040

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214180420301409; https://doaj.org/toc/2214-1804

URL الوصول: https://doaj.org/article/4d575ed143ff4ab788ad2253711af3ac

المؤلفون: James Meehan, Mark Gray, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, Jennifer A. Fraser, Amy V. Poole, Ian H. Kunkler, Simon P. Langdon, David Argyle, Arran K. Turnbull

المصدر: Frontiers in Oncology, Vol 10 (2020)

مصطلحات موضوعية: biomarkers of radiosensitivity, breast cancer, precision medicine, molecular signatures of radiosensitivity, biomarkers of radiation-induced toxicity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.00628/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/f1ccff91ed624c99bba0f0182c1ae428

المؤلفون: Boon H Chua, Emma K Link, Ian H Kunkler, Timothy J Whelan, A Helen Westenberg, Guenther Gruber, Guy Bryant, Verity Ahern, Kash Purohit, Peter H Graham, Mohamed Akra, Orla McArdle, Peter O'Brien, Jennifer A Harvey, Carine Kirkove, John H Maduro, Ian D Campbell, Geoff P Delaney, Joseph D Martin, T Trinh T Vu, Thierry M Muanza, Anthony Neal, Ivo A Olivotto

المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: The Lancet, 400(10350), 431-440. ELSEVIER SCIENCE INC
2022, ' Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01) : a randomised, factorial, multicentre, open-label, phase 3 study ', The Lancet, vol. 400, no. 10350, pp. 431-440 . https://doi.org/10.1016/S0140-6736(22)01246-6

مصطلحات موضوعية: Male, Canada, Radiation, Carcinoma, Intraductal, Neoplasm Recurrence, Local/etiology, Breast Neoplasms, Segmental, General Medicine, Mastectomy, Segmental, Radiation Dosage, Neoplasm Recurrence, Local/etiology, Carcinoma, Intraductal, Noninfiltrating, Humans, Female, Noninfiltrating/radiotherapy, Dose Fractionation, Radiation, Neoplasm Recurrence, Local, Dose Fractionation, Mastectomy, Breast Neoplasms/etiology, Carcinoma, Intraductal, Noninfiltrating/radiotherapy, Neoplasm Staging

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6121677becf3da155cf0d7b923fd3f72
https://doi.org/10.1016/s0140-6736(22)01246-6

المؤلفون: Ian H. Kunkler, Linda J. Williams, Wilma J.L. Jack, David A. Cameron, J. Michael Dixon

المصدر: Kunkler, I H, Williams, L, J.L Jack, W, Cameron, D A & Dixon, M J 2023, ' Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer ', New England Journal of Medicine, vol. 388, no. 7, pp. 585-594 . https://doi.org/10.1056/NEJMoa2207586

مصطلحات موضوعية: Surgery General, Breast Cancer, Surgery, General Medicine, Hematology/Oncology, Treatments in Oncology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3232ef2d8787ea673458be64bb7bd5b8
https://www.pure.ed.ac.uk/ws/files/325530882/PRIMEII22_07586.R3_41122Kunkler_DLL.pdf

المؤلفون: Nicola J. Farrer, Geoff S. Higgins, Ian H. Kunkler

المصدر: Farrer, N J, Higgins, G S & Kunkler, I 2022, ' Radiation-induced prodrug activation: extending combined modality therapy for some solid tumours ', British Journal of Cancer .

مصطلحات موضوعية: Cancer Research, Oncology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b29f511ea355a51eaf6df2bdeba696
https://hdl.handle.net/20.500.11820/0411b2b6-9b55-49fd-b08b-5d20aeef0095

المؤلفون: Nicola J, Farrer, Geoff S, Higgins, Ian H, Kunkler

المصدر: British journal of cancer. 126(9)

مصطلحات موضوعية: Doxorubicin, Neoplasms, Humans, Prodrugs, Chemoradiotherapy, Combined Modality Therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dcba9cf0724eaaecdad0eb569588c3ce
https://pubmed.ncbi.nlm.nih.gov/35217798

المؤلفون: Boon H, Chua, Emma K, Link, Ian H, Kunkler, Ivo A, Olivotto

المصدر: The Lancet. 401:24

مصطلحات موضوعية: General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b9dc2363d3586b68be0d599b690589
https://doi.org/10.1016/s0140-6736(22)02373-x

المؤلفون: Ian H, Kunkler, Boon H, Chua

المصدر: Current opinion in oncology. 33(6)

مصطلحات موضوعية: Postoperative Care, Meta-Analysis as Topic, Humans, Breast Neoplasms, Female, Radiotherapy, Adjuvant, Mastectomy, Randomized Controlled Trials as Topic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5b75837cb785f5a73af3fc0961b79011
https://pubmed.ncbi.nlm.nih.gov/34494609

المؤلفون: Peter Graham, Mohamed Akra, Emma Link, Boon Chua, Timothy J. Whelan, G. Bryant, Jennifer Harvey, J Ludbrook, Ivo A. Olivotto, Ian Campbell, Guenther Gruber, Kash Purohit, O. McArdle, Geoff P. Delaney, A. Helen Westenberg, Joseph Martin, John H. Maduro, Ian H. Kunkler, Claire Phillips, Verity Ahern, C. Kirkove

المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: Olivotto, I A, Link, E, Phillips, C, Whelan, T J, Bryant, G, Kunkler, I, Westenberg, H, Purohit, K, Ahern, V, H. Graham, P, Akra, M, McArdle, O, Ludbrook, J J, Harvey, J A, Maduro, J H, Kirkove, C, Gruber, G, Martin, J D, Campbell, I D & Delaney, G P & Chua, B H 2019, ' International comparison of cosmetic outcomes of breast conserving surgery and radiation therapy for women with ductal carcinoma in situ of the breast ', Radiotherapy and Oncology . https://doi.org/10.1016/j.radonc.2019.07.024
Radiotherapy and Oncology, 142, 180-185. ELSEVIER IRELAND LTD

مصطلحات موضوعية: Cosmetic outcomes, medicine.medical_treatment, Mastectomy, Segmental, 030218 nuclear medicine & medical imaging, Breast cancer, 0302 clinical medicine, QUALITY-OF-LIFE, BREAST CONSERVATION, SURGICAL-PROCEDURES, Breast-conserving surgery, Medicine, Fractionation, Boost, Randomized Controlled Trials as Topic, Aged, 80 and over, CONSERVATIVE SURGERY, Carcinoma, Ductal, Breast, Breast conservation, Hematology, Middle Aged, CANCER, cosmetic outcomes, RADIOTHERAPY START TRIALS, Oncology, 030220 oncology & carcinogenesis, Female, Radiology, boost, Carcinoma in Situ, Mastectomy, Adult, medicine.medical_specialty, Breast Neoplasms, PATIENT, 03 medical and health sciences, breast cancer, Whole Breast Irradiation, Humans, Radiology, Nuclear Medicine and imaging, fractionation, radiotherapy, Aged, Radiotherapy, business.industry, Carcinoma in situ, EORTC BOOST, Cosmesis, STANDARDIZATION, Ductal carcinoma, medicine.disease, IRRADIATION, Radiation therapy, Dose Fractionation, Radiation, FOLLOW-UP, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b666fc5cf437a6af83fe7a21bb4447
https://doi.org/10.1016/j.radonc.2019.07.024

المؤلفون: Ewen O. Blair, David Argyle, Mark Gray, Andreas Tsiamis, Camelia Dunare, Alan F. Murray, Ian H. Kunkler, Jamie R. K. Marland, Mark A Potter, Alex Dyson, Mervyn Singer, James Meehan

المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology
Gray, M E, Marland, J R K, Dunare, C, Blair, E O, Meehan, J, Tsiamis, A, Kunkler, I H, Murray, A, Argyle, D, Dyson, A, Singer, M & A Potter, M 2019, ' In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension ', American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 317, no. 2, pp. G242-G252 . https://doi.org/10.1152/ajpgi.00050.2019

مصطلحات موضوعية: Materials science, Physiology, Electrochemistry, Hypoxemia, Oxygen Consumption, In vivo, miniaturized electrochemical oxygen sensor, Ischemia, Mesenteric Artery, Superior, Physiology (medical), Materials Testing, Mesenteric Vascular Occlusion, medicine, Animals, Surface Tension, Monitoring, Physiologic, hypoxemia, Hepatology, Gastroenterology, Reproducibility of Results, Rodent model, intestinal serosal tissue oxygen tension, Oxygen tension, Rats, Intestines, Oxygen, intestinal resection and anastomosis, Dimensional Measurement Accuracy, Microtechnology, medicine.symptom, superior mesenteric artery occlusion, Oxygen sensor, Biomedical engineering, RC, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce413b8499919c4733d80945afb7c8b9
http://europepmc.org/articles/PMC6734375

المؤلفون: Simon P. Langdon, Andrea Angeli, Carol Ward, Marta Ferraroni, Silvia Bua, Ian H. Kunkler, Fabrizio Carta, Claudiu T. Supuran, Abdul-Malek S. Al-Tamimi, Murat Bozdag

المصدر: Bozdag, M, Ferraroni, M, Ward, C, Carta, F, Bua, S, Angeli, A, Langdon, S P, Kunkler, I H, Al-tamimi, A S & Supuran, C T 2019, ' Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells ', European Journal of Medicinal Chemistry, vol. 182, pp. 111600 . https://doi.org/10.1016/j.ejmech.2019.111600

مصطلحات موضوعية: Gene isoform, Sorafenib, Models, Molecular, Antineoplastic Agents, Breast Neoplasms, Crystallography, X-Ray, 01 natural sciences, Adduct, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Carbonic anhydrase, Drug Discovery, medicine, Tumor Cells, Cultured, Humans, Carbonic Anhydrase Inhibitors, 030304 developmental biology, Cell Proliferation, Pharmacology, 0303 health sciences, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Sulfonamide (medicine), General Medicine, Coumarin, 0104 chemical sciences, Crystallography, Enzyme inhibitor, Cell culture, Drug Design, biology.protein, Female, Drug Screening Assays, Antitumor, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02524e66fb34ba4df7b003ca77463b2d
https://pubmed.ncbi.nlm.nih.gov/31419777

المؤلفون: Carol, Ward, James, Meehan, Mark, Gray, Ian H, Kunkler, Simon P, Langdon, Alan, Murray, David, Argyle

المصدر: Current topics in microbiology and immunology.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::348ab80128ab862ff40cc10a99abfb9b
https://pubmed.ncbi.nlm.nih.gov/30859401

المؤلفون: James Meehan, Carol Ward, David Argyle, Mark Gray, Alan F. Murray, Simon P. Langdon, Ian H. Kunkler

المساهمون: Bagnoli, Fabio, Rappuoli, Rino

المصدر: Ward, C, Meehan, J, Gray, M, Kunkler, I, Langdon, S, Murray, A & Argyle, D 2019, Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment . in F Bagnoli & R Rappuoli (eds), Current Topics in Microbiology and Immunology . Current Topics in Microbiology and Immunology . https://doi.org/10.1007/82_2019_159

مصطلحات موضوعية: Drug, Tumor microenvironment, Clinical effectiveness, business.industry, media_common.quotation_subject, Cancer, Bioinformatics, medicine.disease, Precision medicine, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Cancer cell, medicine, In patient, business, 030215 immunology, media_common

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf850ab8f8a6c746ffd5f7cfc5d2ce43
https://hdl.handle.net/20.500.11820/006e1e3d-8015-4e24-8537-328f53e1616a

المؤلفون: Galina Velikova, Linda Jane Williams, Sarah Willis, J Michael Dixon, Juliette Loncaster, Matthew Hatton, Jacqueline Clarke, Ian H Kunkler, Nicola S Russell, A Alhasso, D Adamson, H Algurafi, R Allerton, C Anandadas, A Bahl, L Barraclough, P Barrett-Lee, U Barthakur, C Bedi, M Beresford, J Bishop, G Blackman, P Bliss, D Bloomfield, M Blunt, T Branson, L Brazil, A Brunt, A Chakrabarti, A Chittalie, M Churn, J Clarke, S Cleator, P Crellin, F Danwata, S De-Silva-Minor, A Dhadda, A Eicholz, I Fernando, J Forrest, J Fraser, K Geropantas, A Goodman, R Grieve, M Griffin, M Hadaki, A Hall, M Hatton, J Hicks, S Hignett, M Hogg, R Jyothirmayi, M Khan, S Kumar, P Lawton, D Lee, C Lewinski, C Lim, I Locke, J Loncaster, G Lumsden, S Lupton, B Magee, J Marshall, S Masinghe, C McGregor, M McLennan, P Memtsa, D Milanovic, V Misra, N Mithal, MB Mukesh, A Neal, S Needleman, M Persic, M Quigley, S Raj, P Riddle, D Ritchie, F Roberts, P Robson, H Roe, M Rolles, N Shah, R Sharma, E Sherwin, P Simmonds, G Skailles, S Skaria, W Soe, R Sripadam, A Stevens, A Stockdale, N Storey, I Syndikus, N Thorp, S Upadhyay, M Varughese, N Walji, R Welch, T Wells, V Wolstenholme, P Woodings, F Yuille

المصدر: Velikova, G, Williams, L J, Willis, S, Dixon, J M, Loncaster, J, Hatton, M, Clarke, J & Kunkler, I H & Russell, N S 2018, ' Quality of life after postmastectomy radiotherapy in patients with intermediate-risk breast cancer (SUPREMO): 2-year follow-up results of a randomised controlled trial ', The Lancet Oncology, vol. 19, no. 11, pp. 1516-1529 . https://doi.org/10.1016/S1470-2045(18)30515-1

مصطلحات موضوعية: Adult, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Breast Neoplasms, Hospital Anxiety and Depression Scale, law.invention, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Randomized controlled trial, Quality of life, law, Internal medicine, Surveys and Questionnaires, Clinical endpoint, Medicine, Humans, 030212 general & internal medicine, Mastectomy, Aged, Neoplasm Staging, Intention-to-treat analysis, business.industry, Middle Aged, medicine.disease, R1, Radiation therapy, Europe, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Quality of Life, Lymph Node Excision, Female, Radiotherapy, Adjuvant, Dose Fractionation, Radiation, Neoplasm Grading, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7eefbeb3155fb3d0fff68395c27216
https://hdl.handle.net/20.500.11820/d9fb43b0-f195-426b-9cad-a09a048fb401

المؤلفون: Mark E, Gray, James, Meehan, Ewen O, Blair, Carol, Ward, Simon P, Langdon, Linda R, Morrison, Jamie R K, Marland, Andreas, Tsiamis, Ian H, Kunkler, Alan, Murray, David, Argyle

المصدر: Journal of Biomedical Materials Research. Part B, Applied Biomaterials

مصطلحات موضوعية: Polymers, foreign body response, Transplantation, Heterologous, Biocompatible Materials, Biosensing Techniques, Xylenes, Original Research Report, Mice, biocompatibility, Original Research Reports, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Platinum, implantable biosensor, tumor xenograft model, Epoxy Resins, Foreign-Body Reaction, Silicon Compounds, Neoplasms, Experimental, Prostheses and Implants, Silicon Dioxide, Fluorocarbon Polymers, Smart Materials, innate immune response, Female, Collagen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9991c3ec749c59048c9f4f7ec8563623
https://pubmed.ncbi.nlm.nih.gov/30367816

المؤلفون: Ian H. Kunkler, John R. Benson, Ismail Jatoi

المصدر: NPJ Breast Cancer
npj Breast Cancer, Vol 4, Iss 1, Pp 1-8 (2018)
Jatoi, I, Benson, J R & Kunkler, I 2018, ' Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality? ', Clinical breast cancer, vol. 4, no. 1 . https://doi.org/10.1038/s41523-018-0061-y

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, medicine.medical_treatment, lcsh:RC254-282, law.invention, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Randomized controlled trial, law, Internal medicine, medicine, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, Survival analysis, business.industry, Abscopal effect, Immunotherapy, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Radiation therapy, 030104 developmental biology, 030220 oncology & carcinogenesis, Perspective, Immunogenic cell death, business, Adjuvant

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93698a41da5ed1aba381824510bc656a
https://arro.anglia.ac.uk/id/eprint/702911/1/Benson_2018.pdf

المؤلفون: Joyce Tait, Theresa Ikegwuonu, Ian H. Kunkler, Alan F. Murray, Gill Haddow

المصدر: Ikegwuonu, T, Haddow, G, Tait, J, Murray, A F & Kunkler, I H 2018, ' Horizon scanning implanted biosensors in personalising breast cancer management : First pilot study of breast cancer patients views ', Health Science Reports, vol. 1, no. 4, e30, pp. 1-9 . https://doi.org/10.1002/hsr2.30
Health Science Reports

مصطلحات موضوعية: Oncology, medicine.medical_specialty, medicine.medical_treatment, biosensor, Systemic therapy, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, breast cancer, Internal medicine, Cancer centre, medicine, cancer, 030212 general & internal medicine, Horizon scanning, Research Articles, Adjuvant radiotherapy, business.industry, Cancer, General Medicine, medicine.disease, patient acceptability, 3. Good health, Radiation therapy, implantable technology, 030220 oncology & carcinogenesis, oncology, business, adjuvant radiotherapy, adjuvant radiography, Mastectomy, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace64168656ce43cf162a6107e6eb2d1
https://www.pure.ed.ac.uk/ws/files/57107488/hsr2.30.pdf