المؤلفون: Adelphe M. Mfuh, Jeffrey A. Boerth, Gayathri Bommakanti, Christina Chan, Alex J. Chinn, Erin Code, Patrick J. Fricke, Kathryn A. Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J. Hughes, Meizhong Jin, Vasudev Kantae, Stefan L. Kavanagh, Michelle L. Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R. Quinn, Iswarya Reddy, Graeme R. Robb, Kevin J. Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J. Walsh, Jamie Ware, Iain D. G. Watson, Min-Wei Ye, Gail L. Wrigley, Andrew X. Zhang, Yun Zhang, Neil P. Grimster

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Plant Biology, Virology, Chemical Sciences not elsewhere classified, provided direct evidence, downstream signal within, mediated protein modulation, b negatively regulates, b ligase activity, 31 , based drug discovery, 50 , cellular modulation, b inhibitors, b autoubiquitination, b ), therapeutic potential, tcr axis, targeting approaches, regulating effector, lymphoma proto, induces il

Relation: https://figshare.com/articles/journal_contribution/Discovery_Optimization_and_Biological_Evaluation_of_Arylpyridones_as_Cbl_b_Inhibitors/25006678

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c02083.s001
https://figshare.com/articles/journal_contribution/Discovery_Optimization_and_Biological_Evaluation_of_Arylpyridones_as_Cbl_b_Inhibitors/25006678

المؤلفون: Emily Murrell (8415951), Junchao Tong (1291809), David Smil (1294233), Taira Kiyota (2507788), Ahmed M. Aman (1884958), Methvin B. Isaac (3040443), Iain D. G. Watson (10693014), Neil Vasdev (1291818)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Mental Health, Chemical Sciences not elsewhere classified, brain penetrant ALK 2 inhibitor, Preliminary Neuroimaging, drug discovery, science approach, brain permeability, PET imaging, pontine glioma, positron emission tomography, DIPG, ALK 2, SUV, 11 C-methylation, Inhibitor, Leveraging Open Science Drug Develo., brain uptake, ALK 2 inhibitors, gene encoding activin receptor-like., brainstem cancer, 11 C-labeled radiotracers

Relation: https://figshare.com/articles/journal_contribution/Leveraging_Open_Science_Drug_Development_for_PET_Preliminary_Neuroimaging_of_sup_11_sup_C_Labeled_ALK2_Inhibitors/14477904

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00127.s001

المؤلفون: Junchao Tong, Iain D. G. Watson, Methvin Isaac, Emily Murrell, Ahmed Aman, Neil Vasdev, Taira Kiyota, David Smil

المصدر: ACS Medicinal Chemistry Letters. 12:846-850

مصطلحات موضوعية: medicine.diagnostic_test, Drug discovery, business.industry, Organic Chemistry, Cancer, Blood–brain barrier, medicine.disease, Biochemistry, Pons, medicine.anatomical_structure, Drug development, Neuroimaging, Positron emission tomography, Drug Discovery, medicine, Cancer research, Brainstem, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6c8099703a0402af62cb019ae550fc9a
https://doi.org/10.1021/acsmedchemlett.1c00127

المؤلفون: Emily, Murrell, Junchao, Tong, David, Smil, Taira, Kiyota, Ahmed M, Aman, Methvin B, Isaac, Iain D G, Watson, Neil, Vasdev

المصدر: ACS Medicinal Chemistry Letters

مصطلحات موضوعية: Positron emission tomography, Letter, DIPG, Carbon-11, ALK2, Blood-brain barrier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b97348232ab1a42754269731421d12b7
https://pubmed.ncbi.nlm.nih.gov/34055235

المؤلفون: Iain D. G. Watson, Methvin Isaac, Emily Murrell, Neil Vasdev, Junchao Tong, David Smil

المصدر: Nuclear Medicine and Biology. :S41

مصطلحات موضوعية: Cancer Research, Open science, Neuroimaging, Chemistry, Molecular Medicine, Radiology, Nuclear Medicine and imaging, Neuroscience, Receptor like kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7842334a4cd5e0d6fcb25f879357e5e9
https://doi.org/10.1016/s0969-8051(21)00330-9

المؤلفون: Brian J. Wilson, Methvin Isaac, Ayome Abibi, Michael Prakesch, Ratheesh Subramaniam, Ahmed Aman, Doug Kuntz, Rima Al-awar, Elijus Undzys, Justin Morin, Jeffrey Winston, Neil C. Pomroy, Craig Strathdee, Carly Griffin, Pandiaraju Subramanian, Herman Cheung, Gil G. Privé, Iain D. G. Watson, Taira Kiyota, Manuel Chan, Richard Marcellus, Anh Chau, Gennady Poda, Babu Joseph, David Uehling, Brigitte L. Thériault, Ahmed Mamai

المصدر: Cancer Research. 79:7-7

مصطلحات موضوعية: Cancer Research, Cellular activity, Oncology, immune system diseases, hemic and lymphatic diseases, Philosophy, Cancer research, medicine, Germinal center, BCL6, B-cell lymphoma, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2715de60b777616a8c4dfd559d76036b
https://doi.org/10.1158/1538-7445.am2019-7

المؤلفون: Robert H. Morris, Marco Zimmer-De Iuliis, Iain D. G. Watson, Andrei K. Yudin

المصدر: Canadian Journal of Chemistry. 87:54-62

مصطلحات موضوعية: Allylic rearrangement, Olefin fiber, Stereochemistry, Organic Chemistry, Regioselectivity, chemistry.chemical_element, General Chemistry, Aziridine, Medicinal chemistry, Catalysis, chemistry.chemical_compound, chemistry, Nucleophile, Phosphine, Amination, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::810d096ec8e3d1fe3310b3f774efaf4d
https://doi.org/10.1139/v08-078

المؤلفون: Andrei K. Yudin, Lily Yu, Iain D. G. Watson

المصدر: Accounts of Chemical Research. 39:194-206

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, chemistry.chemical_element, Organic chemistry, Stereoselectivity, General Medicine, General Chemistry, Aziridine, Ring (chemistry), Combinatorial chemistry, Nitrogen, Enamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9662e6c8c01bdc3d8c4044cc7d4ec80e
https://doi.org/10.1021/ar050038m

المؤلفون: Andrei K. Yudin, Iain D. G. Watson

المصدر: Journal of the American Chemical Society. 127:17516-17529

مصطلحات موضوعية: Allylic rearrangement, Reaction mechanism, chemistry.chemical_element, Regioselectivity, General Chemistry, Biochemistry, Catalysis, Colloid and Surface Chemistry, chemistry, Nucleophile, Organic chemistry, Solvent effects, Isomerization, Amination, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dd95553ba0251e61577d4585bbcc5c
https://doi.org/10.1021/ja055288c

المؤلفون: Ian W. J. Still, Iain D. G. Watson

المصدر: Synthetic Communications. 31:1355-1359

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Sodium, Aryl, Organic Chemistry, chemistry.chemical_element, Organic chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28f6b43e58e6e315ed18d423af4e8a8c
https://doi.org/10.1081/scc-100104044

المؤلفون: Doris Tang, Rima S. Al-awar, Pandiaraju Subramanian, M. Monzur Morshed, Iain D. G. Watson, Matthäus Getlik, Brian J. Wilson

المصدر: ChemInform. 44

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Nucleophilic aromatic substitution, Rearrangement reaction, General Medicine, Halo, Triethylamine, Medicinal chemistry, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a925814f0fcf09c1b63b4ca709296d9
https://doi.org/10.1002/chin.201341164

المؤلفون: Iain D. G. Watson, Andrei K. Yudin, Igor Dubovyk

المصدر: ChemInform. 44

مصطلحات موضوعية: Allylic rearrangement, Ligand, fungi, food and beverages, chemistry.chemical_element, General Medicine, Combinatorial chemistry, humanities, Pyrrole derivatives, Catalysis, Solvent, chemistry, Selectivity, Amination, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::49dc10784886a13cc610f08b61aefa4e
https://doi.org/10.1002/chin.201329031

المؤلفون: Doris Tang, Matthäus Getlik, Rima S. Al-awar, M. Monzur Morshed, Pandiaraju Subramanian, Iain D. G. Watson, Brian J. Wilson

المصدر: The Journal of organic chemistry. 78(11)

مصطلحات موضوعية: Substitution reaction, Models, Molecular, Radical-nucleophilic aromatic substitution, Molecular Structure, Stereochemistry, Pyridines, Organic Chemistry, Crystallography, X-Ray, Medicinal chemistry, chemistry.chemical_compound, chemistry, Nucleophilic aromatic substitution, Acetamides, Nucleophilic substitution, Ethylamines, Hydrocarbons, Chlorinated, Molecule, Rearrangement reaction, Triethylamine, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6ff095e4f219cf3602b8819df2623a
https://pubmed.ncbi.nlm.nih.gov/23700973

المؤلفون: F. Dean Toste, Iain D. G. Watson

المصدر: ChemInform. 44

مصطلحات موضوعية: chemistry.chemical_classification, Olefin fiber, Cycloisomerization, chemistry, Enyne, Carbon–carbon bond, Intramolecular force, Enantioselective synthesis, Hydroacylation, General Medicine, Combinatorial chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09decf8c67f2dcd273a5692b970becf8
https://doi.org/10.1002/chin.201310218

المؤلفون: Igor Dubovyk, Iain D. G. Watson, Andrei K. Yudin

المصدر: The Journal of organic chemistry. 78(4)

مصطلحات موضوعية: Allylic rearrangement, Chemistry, Organic Chemistry, Electrophile, Organic chemistry, Regioselectivity, chemistry.chemical_element, Metathesis, Isomerization, Amination, Catalysis, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bc414fb1ccf0fc709ca384ca73ceba
https://pubmed.ncbi.nlm.nih.gov/23327430

المؤلفون: Iain D. G. Watson, Nicholas Afagh, Andrei K. Yudin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c3823f7107c4688772df36fe2c2e4226
https://doi.org/10.1002/0471264229.os087.17

المؤلفون: Ian W. J. Still, Iain D. G. Watson

المصدر: ChemInform. 32

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Aryl, General Medicine, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe0e86997cebddd930820590a14419d7
https://doi.org/10.1002/chin.200143104

المؤلفون: F. Dean Toste, Iain D. G. Watson, Mikimoto Katsukawa, Minoru Uemura

المصدر: ChemInform. 40

مصطلحات موضوعية: Allylic rearrangement, Chemistry, Propargyl, Enantioselective synthesis, General Medicine, Carbocation, Benzopyrans, Oxonium ion, Medicinal chemistry, Stereocenter, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6663fcef3b9c8cdc52d3494e8a9ddda7
https://doi.org/10.1002/chin.200929139

المؤلفون: Stefanie Ritter, F. Dean Toste, Iain D. G. Watson

المصدر: ChemInform. 40

مصطلحات موضوعية: Cyclopropanation, Chemistry, Intramolecular force, Yield (chemistry), Polymer chemistry, Enantioselective synthesis, General Medicine, Ring (chemistry), Carbenoid, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bd5ddf2c0304f2056b4aa22876ea3afb
https://doi.org/10.1002/chin.200926105

المؤلفون: F. Dean Toste, Iain D. G. Watson, David J. Gorin

المصدر: ChemInform. 39

مصطلحات موضوعية: Annulation, Chemistry, Organic chemistry, General Medicine, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c897a6a7fe31490542c5abd492bf1f9
https://doi.org/10.1002/chin.200831122