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المؤلفون: Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: MSC, mesenchymal stem cells, MDSCs, myeloid-derived suppressor cells, Angiogenesis, PDAC, pancreatic ductal adenocarcinoma, Cell, Review, Exosomes, hTERT, human telomerase reverse transcriptase, Metastasis, PCC, pheochromocytoma, HTR, hormone therapy-resistant, 0302 clinical medicine, DNM3, dynamin 3, DC, dendritic cells, miRNA, microRNA, Tumor immunity, CDH3, cadherin 3, NKEXOs, natural killer cell-derived exosomes, PA, phosphatidic acid, CD-UPRT, cytosine deaminase-uracil phosphoribosyltransferase, General Pharmacology, Toxicology and Pharmaceutics, HA, hyaluronic acid, HIF1, hypoxia-inducible factor 1, 0303 health sciences, PS, phosphatidylserine, ECM, extracellular matrix, medicine.anatomical_structure, PGL, paraganglioma, circRNAs, circular RNAs, 030220 oncology & carcinogenesis, CRC, colorectal cancer, MVB, multivesicular body, Drug delivery, APCs, antigen-presenting cells, RCC, renal cell carcinoma, ESCRT, endosomal sorting complex required for transport, Signal transduction, DLBCL, diffuse large B-cell lymphoma, EMT, epithelial–mesenchymal transition, ILVs, intraluminal vesicles, HUVECs, human umbilical vein endothelial cells, PD-L1, programmed cell death receptor ligand 1, CCRCC, clear-cell renal cell carcinoma, Del-1, developmental endothelial locus-1, TSG101, tumor susceptibility gene 101, RM1-950, ABCA3, ATP-binding cassette transporter A3, Biology, PI, phosphatidylinositol, 03 medical and health sciences, Immune system, DEXs, DC-derived exosomes, NSCLC, non-small cell lung cancer, MIF, migration inhibitory factor, medicine, PTRF, polymerase I and transcript release factor, 030304 developmental biology, GPC1, glypican-1, SM, sphingomyelin, lncRNAs, long non-coding RNAs, Cancer, NNs, nanoparticles, medicine.disease, TEX, tumor-derived exosomes, Microvesicles, mtDNA, mitochondrial DNA, SNARE, soluble NSF-attachment protein receptor, Drug resistance, lamp2b, lysosome-associated membrane glycoprotein 2b, ncRNA, non-coding RNAs, Cancer research, dsDNA, double stranded DNA, Therapeutics. Pharmacology, HCC, hepatocellular carcinoma, Tumor metastasis, Biomarkers, CAFs, cancer-associated fibroblasts
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المؤلفون: Xiaohuan Xia, Jialin C. Zheng, Yi Wang
المصدر: Fundamental Research
مصطلحات موضوعية: SARS, Severe acute respiratory syndrome, TAR, Trans-activation response element, viruses, Review, N protein, Nucleocapsid protein, ESCRT, Endosomal sorting complexes required for transport, RLRs, RIG-I-like receptors, ZIKV, Zika virus, Pathogenesis, MVBs, Multivesicular bodies, TBEV, Tick-borne encephalitis virus, Tsg101, Tumor susceptibility gene 101, HCQ, Hydroxychloroquine, CQ, Chloroquine, Receptor, LPS, Lipopolysaccharide, Alix, ALG-2-interacting protein X, COVID-19, Coronavirus disease 2019, biology, PMEL, Premelanosome protein, CNS, Central nervous system, Vesicle, LMP1, Latent membrane protein 1, HRV, Human rhinovirus, EEs, Early endosomes, ZIKA, IAV, Influenza A virus, WNV, West Nile virus, HIV, Human immunodeficiency virus, NDEVs, Neural-derived EVs, EBOV, Ebola virus, Extracellular vesicle, PB, Placental barrier, M protein, Membrane protein, TIM4, T cell immunoglobulin and mucin protein 4 TLRs: Toll-like receptors, RNA virus, SGR, Subgenomic replicon, E protein, Envelope glycoprotein, JEV, Japanese encephalitis virus, Virus, HCV, Hepatitis C virus, nSMase2, Neutral sphingomyelinase-2, pDCs, Plasmacytoid dendritic cells, EBV, Epstein Barr virus, ACE2, Angiotensin-converting enzyme 2, BALF, Bronchoalveolar lavage fluid, HAV, Hepatitis A virus, CV, Coxsackievirus, TMPRSS2, Transmembrane protease serine type 2, EVs, Extracellular vesicles, MHC, Major histocompatibility complex, TNF-α, Tissue necrosis factor-alpha, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, MERS, Middle East respiratory syndrome, MVs, Microvesicles, PV, Poliovirus, RNA, Outbreak, COVID-19, HIV, ARF6, Adenosine diphosphate ribosylation factor 6, IL-1β, Interleukin-1β, S protein, Spike glycoprotein, miRNA, MicroRNA, biology.organism_classification, Virology, Microvesicles, Exosome, PtdSer, phosphatidylserine, HFMD, Hand-foot-and-mouth disease, DENV, Dengue virus, EV71, Enterovirus 71, ILVs, Intraluminal vesicles
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المؤلفون: Michael Neumaier, Katja Nitschke, Hesham A. Abdel-Baset, Phillip Nuhn, Sara Alameldin, Maren Hedtke, Victor Costina
المصدر: Practical Laboratory Medicine
Practical Laboratory Medicine, Vol 26, Iss, Pp e00241-(2021)مصطلحات موضوعية: Medicine (General), FDR, false discovery rate, Clinical Biochemistry, Size-exclusion chromatography, Exosomes, Proteomics, CSF, cerebrospinal fluid, UC, ultracentrifugation, R5-920, Liquid chromatography–mass spectrometry, miRNA, microRNA, MVBs, multivesicular bodies, ctDNA, circulating tumor DNA, Lipid bilayer, QD1-999, Chromatography, Mass spectrometry, AGO2, Argonaute protein, Radiological and Ultrasound Technology, Chemistry, Vesicle, EVs, extracellular vesicles, Blood proteins, Microvesicles, Human plasma, cfNAs, Cell-free nucleic acids, SEC, size exclusion chromatography, Ultracentrifuge, Ultracentrifugation, ILVs, intraluminal vesicles, Research Article
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المؤلفون: Ningning Yang, Venkatareddy Nadithe, Dinh Ha
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 6, Iss 4, Pp 287-296 (2016)مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, MVB, multi-vesicular body biogenesis, ALIX, ALG-2 interacting protein X, Hsp, heat shock proteins, HEK293, human embryonic kidney cell line 293, Review, VPS4, vacuolar protein sorting-associated protein 4, Exosomes, miRNA, micro RNA, 0302 clinical medicine, DNA, deoxyribonucleic acid, General Pharmacology, Toxicology and Pharmaceutics, BBB, blood–brain barrier, IL-6, interleukin-6, TNF-α, tumor necrosis factor α, RPE1, retinal pigment epithelial cells 1, Extracellular vesicles, mRNA, messenger RNA, Drug delivery systems, HIV, human immunodeficiency virus, MAPK-1, mitogen-activated protein kinase 1, EpCAM, epithelial cell adhesion molecule, PBMC, peripheral blood mononuclear cells, siRNA, small interference RNA, 030220 oncology & carcinogenesis, Drug delivery, ATPase, adenosine triphosphatase, Drug carrier, ILVs, intraluminal vesicles, Pharmaceutical drug, HeLa, Henrietta Lacks cells, CD, cluster of differentiation, Nanotechnology, TSG101, tumor susceptibility gene 101, Biology, Intracellular membrane, 03 medical and health sciences, CCK-8, cell counting kit-8, ROS, reactive oxygen species, ESCRT, endosomal sorting complexes required for transport, EV, extracellular vesicle, medicine, MHC, major histocompatibility complex, MPS, mononuclear phagocyte system, PD, Parkinson’s disease, PEG, polyethylene glycol, EGF, epidermal growth factor, lcsh:RM1-950, Polymeric nanoparticles, Microvesicles, kRAS, Kirsten rat sarcoma, EGFR, epidermal growth factor receptor, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, Immunology, Nanocarrier, RNA, ribonucleic acid, LPS, lipopolysaccharides, DIL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate, HMGA2, high-mobility group AT-hook protein, Nanocarriers, DNA - Deoxyribonucleic acid
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المؤلفون: Matilde Clarissa Malfatti, Isabella Parolini, Agostina Pietrantoni, Gianluca Tell, Jessica Corsi, Giovanna Mangiapane, Massimo Sanchez, Vito Giuseppe D'Agostino, Kristel Conte
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, HMDS, hexamethyldisilazane, DNA Repair, DAMP, damage-associated molecular pattern, ds_r8oxoG:dC, oxidized ribonucleotide embedded in dsDNA, Genotoxic Stress, Exosomes, Biochemistry, Doxo, doxorubicin, apurinic/apyrimidinic endodeoxyribonuclease 1, base excision repair biomarker, exosomes, extracellular vesicles, genotoxic damage, proteasome, Animals, Cell Line, DNA-(Apurinic or Apyrimidinic Site) Lyase, Humans, NTA, nanoparticle tracking analysis, miRNA, microRNA, MVBs, multivesicular bodies, TSA, trichostatin A, AML, acute myeloid leukemia, BER, base excision repair, Regulation of gene expression, Chemistry, CDDP, cisplatin, ds_dF:dC, abasic deoxyribonucleotides in dsDNA, NPM1, nucleophosmin 1, GM130, Golgi apparatus protein, EVs, extracellular vesicles, rGST, recombinant GST, NBI, nickel-based isolation, Base excision repair, NSCLC, nonsmall-cell lung cancer, Endodeoxyribonuclease, Cell biology, ESCRT, endosomal sorting complex required for transport, ILVs, intraluminal vesicles, Research Article, alpha, amplified luminescence proximity homogeneous assay, rGST-APE1WT, recombinant GST APE1WT protein, rGST-APE1NΔ33, recombinant GST APE1NΔ33 protein, SASP, senescence-associated secretory phenotype, APE1/Ref1, apurinic/apyrimidinic endodeoxyribonuclease 1/redox factor1, DDR, DNA damage response, TNBC, triple-negative breast cancer, EVs/exo, EVs containing exosomes, 03 medical and health sciences, CM, conditioned medium, Extracellular, rAPE1WT, recombinant APE1WT protein, SEM, scanning electron microscopy, AP site, Secretion, hnRNP A2/B1, heterogeneous nuclear ribonucleoprotein A2/B1, rGST-APE1K4pleA, recombinant GST APE1K4pleA protein, RAGE, receptor for advanced glycation end product, EXE, EVs extract, Molecular Biology, ds_rF:dC, abasic ribonucleotide embedded in dsDNA, 030102 biochemistry & molecular biology, DSB, double-strand breaks, Cell Biology, sAPE1, serum APE1, Microvesicles, 030104 developmental biology, NCE, nuclear cell extracts, HCC, hepatocellular carcinoma, TRPS, tunable resistive pulse sensing, ncRNA, noncoding RNA, WCE, whole-cell extract
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المؤلفون: Mehdi Hassanpour, Mohammad Nouri, Jafar Rezaie, Yunes Panahi
المصدر: Infection, Genetics and Evolution
مصطلحات موضوعية: 0301 basic medicine, SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus-2, EBV, Epstein-Barr Virus, STING, Stimulator of INF Genes, DC, Dendritic Cells, EVs, Extracellular Vesicles, MERS, Middle East Respiratory Syndrome, HSV-1, Herpes Simplex Virus 1, PBMNCs, Peripheral Blood Mononuclear Cells, Exosomes, ACE2, Angiotensin-converting Enzyme 2, SARS, Severe Acute Respiratory Syndrome, Molecular Targeted Therapy, ESCRT, Endosomal Sorting Complex Required for Transport, DPP4, Dipeptidyl Peptidase 4, KSHV, Kaposi's Sarcoma-associated Herpesvirus, Extracellular vesicles, ACLF, Acute-on-chronic Liver Failure, PA, Phosphatidic Acid, nSMase, Neutral Sphingomyelinase, Abs, Apoptotic Bodies, Virus Shedding, Cell biology, Infectious Diseases, medicine.anatomical_structure, TIM-1, T-cell Immunoglobulin and Mucin Domain 1, COVID-19, Coronavirus Disease 2019, PBC, Primary Biliary Cirrhosis, ISEV, International Society of Extracellular Vesicles, LIMK, LIM kinase, medicine.symptom, dUTPase, deoxy-uridine triphosphatase, MYLK, Myosin Light Chain Kinase, Signal Transduction, Microbiology (medical), BAL, Bronchoalveolar lavage, MVB, Multivescular Body, ECMO, Extracorporeal Membrane Oxygenation, 030106 microbiology, Inflammation, TMPRSS2, TTSP Family Members Like Transmembrane Protease Serine Type 2, Biology, Antiviral Agents, Microbiology, Exosome, Article, Virus, Alveolar cells, APN, Aminopeptidase N, 03 medical and health sciences, Viral entry, Genetics, medicine, Humans, Secretion, CMV, Cytomegalovirus, Molecular Biology, Ecology, Evolution, Behavior and Systematics, TTSP, Type II Transmembrane Serine Protease, SARS-CoV-2, ILVs, Intraluminal Vesicles, MVs, Microvesicles, Mesenchymal stem cell, COVID-19, MSCs, Mesenchymal stem cells, Virus Internalization, Microvesicles, COVID-19 Drug Treatment, 030104 developmental biology, Viral infection, LMP-1, Latent Membrane Protein 1, COVID-19 virus, ROCK, Rho-associated protein kinases