المؤلفون: Michael G. Yang (2123170), Myra Beaudoin-Bertrand (4067701), Zili Xiao (2123182), David Marcoux (2182586), Carolyn A. Weigelt (2276455), Shiuhang Yip (1402564), Dauh-Rurng Wu (1402558), Max Ruzanov (5877002), John S. Sack (2375029), Jinhong Wang (34550), Melissa Yarde (1745002), Sha Li (145229), David J. Shuster (2459569), Jenny H. Xie (3385667), Tara Sherry (9610086), Mary T. Obermeier (1436389), Aberra Fura (1436362), Kevin Stefanski (1551436), Georgia Cornelius (1429912), Purnima Khandelwal (4724169), Ananta Karmakar (2236600), Mushkin Basha (7597451), Venkatesh Babu (10151570), Arun Kumar Gupta (7597448), Arvind Mathur (144120), Luisa Salter-Cid (1429873), Rex Denton (2012920), Qihong Zhao (517396), T. G. Murali Dhar (7542971)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, X-ray co-crystal structure, ROR γt, vivo PK profiles, efficacy, BMS -986313 SAR efforts, IL -23-induced acanthosis model, ligand binding domain

Relation: https://figshare.com/articles/journal_contribution/Tricyclic-Carbocyclic_ROR_t_Inverse_Agonists_Discovery_of_BMS-986313/14043458

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01992.s002

المؤلفون: Michael G. Yang (2123170), Myra Beaudoin-Bertrand (4067701), Zili Xiao (2123182), David Marcoux (2182586), Carolyn A. Weigelt (2276455), Shiuhang Yip (1402564), Dauh-Rurng Wu (1402558), Max Ruzanov (5877002), John S. Sack (2375029), Jinhong Wang (34550), Melissa Yarde (1745002), Sha Li (145229), David J. Shuster (2459569), Jenny H. Xie (3385667), Tara Sherry (9610086), Mary T. Obermeier (1436389), Aberra Fura (1436362), Kevin Stefanski (1551436), Georgia Cornelius (1429912), Purnima Khandelwal (4724169), Ananta Karmakar (2236600), Mushkin Basha (7597451), Venkatesh Babu (10151570), Arun Kumar Gupta (7597448), Arvind Mathur (144120), Luisa Salter-Cid (1429873), Rex Denton (2012920), Qihong Zhao (517396), T. G. Murali Dhar (7542971)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, X-ray co-crystal structure, ROR γt, vivo PK profiles, efficacy, BMS -986313 SAR efforts, IL -23-induced acanthosis model, ligand binding domain

Relation: https://figshare.com/articles/dataset/Tricyclic-Carbocyclic_ROR_t_Inverse_Agonists_Discovery_of_BMS-986313/14043455

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01992.s001