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1Academic Journal
المؤلفون: Yu. V. Shevchuk, I. I. Shamigulov, I. V. Sychev, A. V. Kryukov, I. I. Temirbulatov, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev
المصدر: Acta Biomedica Scientifica, Vol 9, Iss 6, Pp 52-62 (2024)
مصطلحات موضوعية: covid-19, remdesivir, adverse drug reactions, hepatotoxicity, pharmacogenetic testing, predictors of adverse reactions, machine learning, risk model, Science
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: l. V. Fedina, i. N. Sychev, K. V. Mirzaev, A. V. Vardanyan, S. V. Glagolev, A. A. Kachanova, P. O. Bochkov, R. V. Shevchenko, S. N. Tuchkova, I. V. Sychev, S. P. Abdullaev, D A. Sychev
المصدر: Рациональная фармакотерапия в кардиологии, Vol 20, Iss 1, Pp 19-26 (2024)
مصطلحات موضوعية: pharmacogenetics, apixaban, af, dvt, personalized therapy, cyp3a4/5, abcb1 gene polymorphisms, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Yu. V. Shevchuk, A. V. Kryukov, I. I. Temirbulatov, I. V. Sychev, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev
المصدر: Фармация и фармакология (Пятигорск), Vol 11, Iss 3, Pp 228-239 (2023)
مصطلحات موضوعية: covid-19, remdesivir, hepatotoxicity, adverse reactions, predictors of adverse reactions, pharmacogenetic study, clinical trial, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: I. V. Sychev, N. P. Denisenko, A. A. Kachanova, A. V. Lapshtaeva, Sh. P. Abdullaev, L. N. Goncharova, K. B. Mirzaev, D. A. Sychev
المصدر: Безопасность и риск фармакотерапии, Vol 11, Iss 2, Pp 231-240 (2023)
مصطلحات موضوعية: angiotensin-converting enzyme inhibitors, enalapril, dry cough, adverse drug reaction, adverse drug reaction predictors, cardiovascular pathology, history of allergies, clinical study, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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5Academic Journal
المصدر: Атеросклероз, Vol 16, Iss 4, Pp 85-92 (2020)
مصطلحات موضوعية: coronary atherosclerosis, high-intensity exercise, sudden death, Diseases of the blood and blood-forming organs, RC633-647.5, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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6Academic Journal
المصدر: Инфекция и иммунитет, Vol 10, Iss 1, Pp 35-48 (2020)
مصطلحات موضوعية: mycobacterium tuberculosis, tuberculosis, receptors of innate immunity, Infectious and parasitic diseases, RC109-216
وصف الملف: electronic resource
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7Academic Journal
المؤلفون: M. Alnaser, I. V. Sychev, Ya. A. Pushkina, L. N. Goncharova
المصدر: Кардиоваскулярная терапия и профилактика, Vol 21, Iss 1 (2022)
مصطلحات موضوعية: st-segment elevation acute coronary syndrome, shortterm prognostic scales, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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8Academic Journal
المؤلفون: T. A. Degaeva, L. N. Goncharova, I. V. Sychev
المصدر: Медицинский совет, Vol 0, Iss 12, Pp 196-200 (2018)
مصطلحات موضوعية: arterial hypertension, methylenetetrahydrofolate reductase gene, cardiovascular complications, nationality, sex, Medicine
وصف الملف: electronic resource
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9Academic Journal
المؤلفون: A. V. Lapshtaeva, I. V. Sychev, L. N. Goncharova
المصدر: Медицинская иммунология, Vol 20, Iss 3, Pp 417-424 (2018)
مصطلحات موضوعية: gene polymorphism, il-1α, tubo-peritoneal infertility, in vitro fertilization, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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10Academic Journal
المؤلفون: A. V. Lapshtaeva, I. V. Evsegneeva, V. V. Novikov, I. V. Sychev, A. V. Karaulov
المصدر: Медицинская иммунология, Vol 20, Iss 1, Pp 115-122 (2018)
مصطلحات موضوعية: il-1α, tubo-peritoneal infertility, pregnancy, in vitro fertilization, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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11Academic Journal
المؤلفون: D. S. Fedorinov, V. K. Lyadov, Sh. P. Abdullayev, A. A. Kachanova, R. N. Heydarov, I. A. Shashkov, V. M. Mikhailovich, S. A. Surzhikov, M. A. Lyadova, I. V. Sychev, V. N. Galkin, I. V. Poddubnaya, D. A. Sychev, Д. С. Федоринов, В. К. Лядов, Ш. П. Абдуллаев, А. A. Качанова, Р. Н. Гейдаров, И. А. Шашков, В. М. Михайлович, С. А. Суржиков, М. А. Лядова, И. В. Сычев, В. Н. Галкин, И. В. Поддубная, Д. А. Сычев
المساهمون: The work was conducted with the support of Russian Science Foundation Grant No. 20-75-10158 – Pharmacogenetic and pharmacokinetic approaches to gastrointestinal cancer chemotherapy based on total body composition., Работа проводилась при поддержке гранта Российского научного фонда №20-75-10158 «Фармакогенетические и фармакокинетические подходы к химиотерапии опухолей желудочно-кишечного тракта на основе анализа состава тела».
المصدر: Meditsinskiy sovet = Medical Council; № 18 (2023); 175-184 ; Медицинский Совет; № 18 (2023); 175-184 ; 2658-5790 ; 2079-701X
مصطلحات موضوعية: TYMS, colorectal cancer, pharmacogenetic testing, DPYD, ERCC1, колоректальный рак, фармакогенетическое тестирование
وصف الملف: application/pdf
Relation: https://www.med-sovet.pro/jour/article/view/7850/6971; Каприн АД, Старинский ВВ, Петрова ГВ (ред.). Состояние онкологической помощи населению России в 2018 году. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России; 2019. 236 с. Режим доступа: https://oncology-association.ru/wp-content/uploads/2020/09/sostoyanie_2018.pdf?ysclid=lnis28yzzl945263948.; Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignar D et al. FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study. J Clin Oncol. 2004;22(2):229–237. https://doi.org/10.1200/JCO.2004.05.113.; De Vita F, Orditura M, Matano E, Bianco R, Carlomagno C, Infusino S et al. A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. Br J Cancer. 2005;92(9):1644–1649. https://doi.org/10.1038/sj.bjc.6602573.; Onakpoya IJ, Heneghan CJ, Aronson JK. Worldwide withdrawal of medicinal products because of adverse drug reactions: a systematic review and analysis. Crit Rev Toxicol. 2016;46(6):477–489. https://doi.org/10.3109/10408444.2016.1149452.; Shahnam A, Ridha Z, Wiese MD, Kichenadasse G, Sorich MJ. Pharmacogenetic and ethnicity influence on oxaliplatin therapy for colorectal cancer: a meta-analysis. Pharmacogenomics. 2016;17(15):1725–1732. https://doi.org/10.2217/pgs-2016-0102.; Meulendijks D, Henricks LM, Sonke GS, Deenen MJ, Froehlich TK, Amstutz U et al. Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data. Lancet Oncol. 2015;16(16):1639–1650. https://doi.org/10.1016/S1470-2045(15)00286-7.; Wigle TJ, Medwid S, Ross C, Schwarz UI, Kim RB. DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation. Curr Oncol. 2023;30(1):663–672. https://doi.org/10.3390/curroncol30010051.; Khalil KA, Musallam HS, Hassan MA, Mahmoud IA. Triplet (FOLFOXIRI) Versus Doublet (FOLFOX or FOLFIRI) Regimen as First Line Treatment in Metastatic Colorectal Carcinoma, a Prospective Phase II, Randomized Controlled Trial. Asian Pac J Cancer Prev. 2022;23(10):3421–3429. https://doi.org/10.31557/APJCP.2022.23.10.3421.; Morel A, Boisdron-Celle M, Fey L, Soulie P, Craipeau MC, Traore S, Gamelin E. Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance. Mol Cancer Ther. 2006;5(11):2895–904. https://doi.org/10.1158/1535-7163.MCT-06-0327.; Sissung TM, Cordes L, Peer CJ, Gandhy S, Redman J, Strauss J, Figg WD. Case report: severe toxicity in an African-American patient receiving FOLFOX carrying uncommon allelic variants in DPYD. Pharmacogenomics. 2021;22(2):81–85. https://doi.org/10.2217/pgs-2020-0120.; Božina N, Bilić I, Ganoci L, Šimičević L, Pleština S, Lešnjaković L, Trkulja V. DPYD polymorphisms c.496A>G, c.2194G>A and c.85T>C and risk of severe adverse drug reactions in patients treated with fluoropyrimidine-based protocols. Br J Clin Pharmacol. 2022;88(5):2190–2202. https://doi.org/10.1111/bcp.15144.; Medwid S, Wigle TJ, Kim RB. Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype. Cancer Chemother Pharmacol. 2023;91(1):97–102. https://doi.org/10.1007/s00280-022-04491-7.; Glewis S, Alexander M, Khabib MNH, Brennan A, Lazarakis S, Martin J et al. A systematic review and meta-analysis of toxicity and treatment outcomes with pharmacogenetic-guided dosing compared to standard of care BSA-based fluoropyrimidine dosing. Br J Cancer. 2022;127(1):126–136. https://doi.org/10.1038/s41416-022-01779-6.; Федянин МЮ, Мамедли ЗЗ, Гордеев СС, Ачкасов СИ, Болотина ЛВ, Гладков ОА и др. Злокачественное новообразование ободочной кишки: клинические рекомендации. 2022. Режим доступа: https://cr.minzdrav.gov.ru/schema/396_3.; Van Triest B, Peters GJ. Thymidylate synthase: a target for combination therapy and determinant of chemotherapeutic response in colorectal cancer. Oncology. 1999;57(3):179–194. https://doi.org/10.1159/000012030.; Kawakami K, Omura K, Kanehira E, Watanabe Y. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res. 1999;19(4B):3249–3252. Available at: https://pubmed.ncbi.nlm.nih.gov/10652619.; Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J et al. Role of Genetic and Nongenetic Factors for Fluorouracil Treatment-Related Severe Toxicity: A Prospective Clinical Trial by the German 5-FU Toxicity Study Group. J Clin Oncol. 2008;26(13):2131–2138. https://doi.org/10.1200/JCO.2006.10.4182.; Sohn KJ, Croxford R, Yates Z, Lucock M, Kim YI. Effect of the Methylenetetrahydrofolate Reductase C677T Polymorphism on Chemosensitivity of Colon and Breast Cancer Cells to 5-Fluorouracil and Methotrexate. J Natl Cancer Inst. 2004;96(2):134–144. https://doi.org/10.1093/jnci/djh015.; Ramos-Esquivel A, Chinchilla R, Valle M. Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer. Anticancer Res. 2020;40(8):4263–4270. https://doi.org/10.21873/anticanres.14428.; Xie C, Zhao J, Hua W, Tan P, Chen Y, Rui J et al. Effect of XPC polymorphisms on the response to platinum-based chemotherapy: a meta-analysis. Onco Targets Ther. 2019;12:3839–3848. https://doi.org/10.2147/OTT.S202617.; Ban N, Takahashi Y, Takayama T, Kura T, Katahira T, Sakamaki S et al. Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide. Cancer Res. 1996;56(15):3577–3582. Available at: https://pubmed.ncbi.nlm.nih.gov/8758929.; Puerta-García E, Urbano-Pérez D, Carrasco-Campos MI, Pérez-Ramírez C, Segura-Pérez A, Calleja-Hernández et al. Effect of DPYD, MTHFR, ABCB1, XRCC1, ERCC1 and GSTP1 on chemotherapy related toxicity in colorectal carcinoma. Surg Oncol. 2020;35:388–398. https://doi.org/10.1016/j.suronc.2020.09.016.; Huang MY, Huang ML, Chen MJ, Lu CY, Chen CF, Tsai PC et al. Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy. Pharmacogenet Genomics. 2011;21(1):18–25. https://doi.org/10.1097/FPC.0b013e3283415124.; Keam B, Im SA, Han SW, Ham HS, Kim MA, Oh DY et al. Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. BMC Cancer. 2008;8:148. https://doi.org/10.1186/1471-2407-8-148.; Badary DM, Elkabsh MM, Mady HH, Gabr A, Kroosh SS. Prognostic and Predictive Role of Excision Repair Cross-complementation Group 1 and Thymidylate Synthase in Colorectal Carcinoma Patients Received FOLFOX Chemotherapy: An Immunohistochemical Study. Appl Immunohistochem Mol Morphol. 2020;28(10):741–747. https://doi.org/10.1097/PAI.0000000000000841.; https://www.med-sovet.pro/jour/article/view/7850
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12Academic Journal
المؤلفون: A. V. Lapshtaeva, T. J. Eremkina, I. V. Sychev, А. В. Лапштаева, Т. Я. Ерёмкина, И. В. Сычёв
المصدر: Pharmacogenetics and Pharmacogenomics; № 1 (2019); 17-24 ; Фармакогенетика и фармакогеномика; № 1 (2019); 17-24 ; 2588-0527 ; 2686-8849
مصطلحات موضوعية: эстрогены, stimulation of superovulation, cytochrome P450, gonadotropins, estrogens, стимуляция суперовуляции, цитохром Р450, гонадотропины
وصف الملف: application/pdf
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Poor responder protocols for in-vitro fertilization: options and results. Current opinion in gynecology and obstetrics. 2008;20(4):374–378. DOI:10.1097/gco.0b013e328305b9b8; Venetis C, Kolibianakis E, Tarlatzi T, Tarlatzis B. Evidence-based management of poor ovarian response. Ann N Y Acad Sci. 2010;1205(1): 199–206. DOI:10.1111/j.1749-6632.2010.05665.x; Андреева М.Г. Оптимизация исходов программы вспомогательных репродуктивных технологий на основании персонифицированного назначения протоколов стимуляции суперовуляции: Дис. . канд. мед. наук. – М: 2006.; Chan W. The ‘ART’ of thrombosis: a review of arterial and venous thrombosis in assisted reproductive technology. Current Opinion in Obstetrics and Gynecology. 2009;21(3):207-218. DOI:10.1097/gco.0b013e328329c2b8; Lazaros L, Xita N, Hatzi E, et al. CYP19gene variants affect the assisted reproduction outcome of women with polycystic ovary syndrome. Gynecological Endocrinol. 2013;29(5):478–482. DOI:10.3109/09513590.2013.774359; Man BL, Hui AC. Cerebral venous thrombosis secondary to ovarian hyperstimulation syndrome. Hong Kong Med. J. 2011;17(2):155-156.; Jing Z, Yanping L. Middle cerebral artery thrombosis after IVF and ovarian hyperstimulation: a case report. Fertil Steril. 2011;95(7):2435.e132435.e15. DOI:10.1016/j.fertnstert.2011.04.002; Karimi Zarchi М, Rouhi М, Abdolahi АH, Hekmatimoghaddam S. The effect of assisted reproductive technologies on gynecological cancer: report of our experiences and literature review. International Journal of Biomedical Science. 2013;9(3):129–134.; Von Horn K, Depenbusch M, Schultze-Mosgau A, Griesinger G. Krebsrisiko nach ovarieller Stimulation. Gynäkologische Endokrinologie. 2014;12(3):162–166. DOI:10.1007/s10304-013-0626-7; Дедов И.И., Тюльпаков А.Н., Чехонин В.П. и др. Персонализированная медицина: современное состояние и перспективы // Вестник Российской академии медицинских наук. – 2012. – Т. 67. № 12. – С. 4-12.; Карабекова Б.А. 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المؤلفون: I. V. Sychev, A. V. Lapshtaeva, L. N. Goncharova
المصدر: Russian Clinical Laboratory Diagnostics. 66:291-296
مصطلحات موضوعية: Infertility, medicine.medical_treatment, Thyrotropin, 030209 endocrinology & metabolism, Fertilization in Vitro, Andrology, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Genotype, medicine, Humans, Genotyping, 030304 developmental biology, 0303 health sciences, In vitro fertilisation, Triiodothyronine, business.industry, Biochemistry (medical), General Medicine, medicine.disease, Thyroxine, Medical Laboratory Technology, Thyroid hormones, Female, Laboratories, business, Hormone
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14
المؤلفون: S. I. Kuzikov, A. N. Mansurov, N. A. Sycheva, I. V. Sychev
المصدر: Journal of Volcanology and Seismology. 14:229-245
مصطلحات موضوعية: Metals and Alloys, Spectral density, Probability density function, 02 engineering and technology, Seismic noise, 010502 geochemistry & geophysics, Geotechnical Engineering and Engineering Geology, 01 natural sciences, Noise, 020303 mechanical engineering & transports, Geophysics, 0203 mechanical engineering, Geology, Seismology, 0105 earth and related environmental sciences
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15
المؤلفون: T. A Degayeva, I. V Sychev, L. N Goncharova
المصدر: Journal of Volgograd State Medical University. 15:50-54
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, Genotype, Methylenetetrahydrofolate reductase gene, medicine, In patient, Myocardial infarction, medicine.disease, business, Gastroenterology
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16
المؤلفون: Ya. A. Frolkina, O. P. Erokhina, L. N. Goncharova, I. V. Sychev, T. V. Goryacheva, A. V. Lapshtaeva
المصدر: University proceedings. Volga region. Medical sciences.
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Medicine, Cognition, business, Intensive care medicine, Essential hypertension, medicine.disease
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17
المؤلفون: I. A. Sycheva, I. V. Sychev
المصدر: 2011 International Siberian Conference on Control and Communications (SIBCON).
مصطلحات موضوعية: Engineering, Adaptive control, business.industry, Asynchronous communication, Control theory, Control system, Voltage control, Automatic frequency control, Control engineering, business, Object (computer science), Induction motor
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18Academic Journal
المؤلفون: I. V. Sycheva, A. V. Soldatenko, S. M. Sychev, A. S. Pankrushova
المصدر: Овощи России, Vol 0, Iss 2, Pp 92-96 (2019)
مصطلحات موضوعية: pest, willow-carrot aphid, population, garden carrot, economic and valuable features, Agriculture
وصف الملف: electronic resource
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19Academic Journal
المؤلفون: I. V. Sycheva
المصدر: Сибирский онкологический журнал, Vol 17, Iss 3, Pp 64-71 (2018)
مصطلحات موضوعية: prostate cancer, brachitherapy, combination radiation therapy, radiation-induced injuries, radiation-induced proctitis, radiation-induced cystitis, radiation-induced urethritis, vesicle-rectal fistula., Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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20
المؤلفون: K. V. Skvortsova, I. S. Modnilcov, I. V. Sychev
المصدر: International Geology Review. 21:231-237
مصطلحات موضوعية: Uranium mineralization, Geochemistry, Mineralogy, Geology