المؤلفون: Adam I. Kramer, MD, MSc, Susan Christian, MSc, PhD, Kirsten Bartels, MSc, Nicol Vaizman, BS, Robert A. Hegele, MD, Liam R. Brunham, MD, PhD

المصدر: CJC Open, Vol 6, Iss 11, Pp 1395-1402 (2024)

مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589790X24003718; https://doaj.org/toc/2589-790X

URL الوصول: https://doaj.org/article/f49f497e8c9a4d53994a602c3b7ba285

المؤلفون: Sherri Bloch, Laura Lévêque, Irva Hertz-Picciotto, Birgit Puschner, Ellen Fritsche, Jördis Klose, Nynke I. Kramer, Maryse F. Bouchard, P. Charukeshi Chandrasekera, Marc-André Verner

المصدر: Environment International, Vol 183, Iss , Pp 108411- (2024)

مصطلحات موضوعية: Risk assessment, In vitro toxicology testing, Mass-balance modeling, Pharmacokinetic modeling, Tolerable daily intake, Biomonitoring equivalent, Environmental sciences, GE1-350

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412023006840; https://doaj.org/toc/0160-4120

URL الوصول: https://doaj.org/article/3c281d7386a04c87b32276cbe2a80b81

المؤلفون: Carolina Nunes, Susana Proença, Giovanna Ambrosini, David Pamies, Aurélien Thomas, Nynke I. Kramer, Marie-Gabrielle Zurich

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: neurotoxicity, in vitro distribution kinetics, hiPSC, lipid metabolism, spheroid, in silico modeling, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1248882/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/0fbfdfac356046d09b4a042507af3896

المؤلفون: Carolina Nunes, Susana Proença, Giovanna Ambrosini, David Pamies, Aurélien Thomas, Nynke I. Kramer, Marie-Gabrielle Zurich

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, neurotoxicity, in vitro distribution kinetics, hiPSC, lipid metabolism, spheroid, in silico modeling, microphysiological system

Relation: https://figshare.com/articles/presentation/Presentation1_Integrating_distribution_kinetics_and_toxicodynamics_to_assess_repeat_dose_neurotoxicity_in_vitro_using_human_BrainSpheres_a_case_study_on_amiodarone_PPTX/24086832

الاتاحة: https://doi.org/10.3389/fphar.2023.1248882.s003
https://figshare.com/articles/presentation/Presentation1_Integrating_distribution_kinetics_and_toxicodynamics_to_assess_repeat_dose_neurotoxicity_in_vitro_using_human_BrainSpheres_a_case_study_on_amiodarone_PPTX/24086832

المؤلفون: Jingxuan Wang, Veronique de Bruijn, Ivonne M.C.M. Rietjens, Nynke I. Kramer, Hans Bouwmeester

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Molecular Biology, Physiology, Pharmacology, Immunology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, novel testing strategy, free testing approach, end points occurring, inflammatory cytokine secretion, bile acid kinetics, silico approach provides, humans current points, predict deoxynivalenol metabolism, based guidance values, 5 , glycochenodeoxycholic acid, 1β secretion, laboratory animals, kg bw, intestinal tissue, intestinal pro, intestinal inflammation, human dietary

Relation: https://figshare.com/articles/journal_contribution/Use_of_Physiologically_Based_Kinetic_Modeling_to_Predict_Deoxynivalenol_Metabolism_and_Its_Role_in_Intestinal_Inflammation_and_Bile_Acid_Kinetics_in_Humans/24893693

الاتاحة: https://doi.org/10.1021/acs.jafc.3c07137.s001
https://figshare.com/articles/journal_contribution/Use_of_Physiologically_Based_Kinetic_Modeling_to_Predict_Deoxynivalenol_Metabolism_and_Its_Role_in_Intestinal_Inflammation_and_Bile_Acid_Kinetics_in_Humans/24893693

المؤلفون: Manon C. Bouwmeester, Yu Tao, Susana Proença, Frank G. van Steenbeek, Roos-Anne Samsom, Sandra M. Nijmeijer, Theo Sinnige, Luc J. W. van der Laan, Juliette Legler, Kerstin Schneeberger, Nynke I. Kramer, Bart Spee

المصدر: Molecules; Volume 28; Issue 2; Pages: 621

مصطلحات موضوعية: drug-induced liver injury, hepatic in vitro model, hepatotoxicity, intrahepatic cholangiocyte organoids, hepatocyte-like cells

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28020621

الاتاحة: https://doi.org/10.3390/molecules28020621

المؤلفون: I. Kramer, Y. Bayer, T. Adeyemo, Y. Mau

المصدر: Hydrology and Earth System Sciences, Vol 25, Pp 1993-2008 (2021)

مصطلحات موضوعية: Technology, Environmental technology. Sanitary engineering, TD1-1066, Geography. Anthropology. Recreation, Environmental sciences, GE1-350

وصف الملف: electronic resource

Relation: https://hess.copernicus.org/articles/25/1993/2021/hess-25-1993-2021.pdf; https://doaj.org/toc/1027-5606; https://doaj.org/toc/1607-7938

URL الوصول: https://doaj.org/article/92ef2f18849140c690cc153fe2e6de28

المؤلفون: Sherri Bloch, Jon A. Arnot, Nynke I. Kramer, James M. Armitage, Marc-André Verner

المصدر: Frontiers in Toxicology, Vol 4 (2022)

مصطلحات موضوعية: IVIVE, mass balance model, repeat dosing, dynamic model, facilitated transport, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.911128/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/9a47dd5fa13344ad8eb4412c61a45963

المؤلفون: O. J. I. Kramer, P. J. de Moel, S. K. R. Raaghav, E. T. Baars, W. H. van Vugt, W.-P. Breugem, J. T. Padding, J. P. van der Hoek

المصدر: Drinking Water Engineering and Science, Vol 14, Pp 53-71 (2021)

مصطلحات موضوعية: Technology, Environmental technology. Sanitary engineering, TD1-1066

وصف الملف: electronic resource

Relation: https://dwes.copernicus.org/articles/14/53/2021/dwes-14-53-2021.pdf; https://doaj.org/toc/1996-9457; https://doaj.org/toc/1996-9465

URL الوصول: https://doaj.org/article/00a4e194539c4909b3a9620a01976eab

المؤلفون: Sebastian Jarzina, Stefano Di Fiore, Bernhard Ellinger, Pia Reiser, Sabrina Frank, Markus Glaser, Jiaqing Wu, Femke J. Taverne, Nynke I. Kramer, Angela Mally

المصدر: Frontiers in Toxicology, Vol 4 (2022)

مصطلحات موضوعية: adverse outcome pathway (AOP), nephrotoxicity, In vitro toxicity testing, QIVIVE, risk assessment, key event relationship, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.864441/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/702a50c3a5af4d85a1746fc787ed859f

المؤلفون: P Korn, I Kramer, F Schlottig, N Tödtmann, U Eckelt, A Bürki, SJ Ferguson, A Kautz, M Schnabelrauch, U Range, M Kneissel, B Stadlinger

المصدر: European Cells & Materials, Vol 37, Pp 333-346 (2019)

مصطلحات موضوعية: Dental implant, osseointegration, osteoporosis animal model, sclerostin antibody, zoledronic acid., Diseases of the musculoskeletal system, RC925-935, Orthopedic surgery, RD701-811

وصف الملف: electronic resource

Relation: http://www.ecmjournal.org/papers/vol037/pdf/v037a20.pdf; https://doaj.org/toc/1473-2262

URL الوصول: https://doaj.org/article/e750cbf5bdf84ed280efdadb777966d9

المؤلفون: Sreya Ghosh, Jonathan De Smedt, Tine Tricot, Susana Proença, Manoj Kumar, Fatemeharefeh Nami, Thomas Vanwelden, Niels Vidal, Paul Jennings, Nynke I. Kramer, Catherine M. Verfaillie

المصدر: Toxics; Volume 10; Issue 1; Pages: 1

مصطلحات موضوعية: mechanistic toxicity, transcriptomics, in vitro toxicology, stem cell derived, hepatocytes, ER stress

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Exposome Analysis and Risk Assessment; https://dx.doi.org/10.3390/toxics10010001

الاتاحة: https://doi.org/10.3390/toxics10010001

المؤلفون: Abdulkarim Najjar, Ans Punt, John Wambaugh, Alicia Paini, Corie Ellison, Styliani Fragki, Enrica Bianchi, Fagen Zhang, Joost Westerhout, Dennis Mueller, Hequn Li, Quan Shi, Timothy W. Gant, Phil Botham, Rémi Bars, Aldert Piersma, Ben van Ravenzwaay, Nynke I. Kramer

المصدر: Archives of Toxicology 96 (2022) 12
Archives of Toxicology, 96(12), 3407-3419

مصطلحات موضوعية: Kinetics, Regulatory acceptance, NAMs, PBK models, Health, Toxicology and Mutagenesis, Animals, Team Toxicology, IVIVE, General Medicine, Toxicology, Models, Biological, Toxicologie, Risk assessment

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfbe3d0dd3f2deef7c7b999e3c70d53
https://doi.org/10.1007/s00204-022-03356-5

المؤلفون: Carolina Nunes, Susana Proença, Giovanna Ambrosini, David Pamies, Aurélien Thomas, Nynke I. Kramer, Marie-Gabrielle Zurich

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, neurotoxicity, in vitro distribution kinetics, hiPSC, lipid metabolism, spheroid, in silico modeling, microphysiological system

Relation: https://figshare.com/articles/dataset/DataSheet1_Integrating_distribution_kinetics_and_toxicodynamics_to_assess_repeat_dose_neurotoxicity_in_vitro_using_human_BrainSpheres_a_case_study_on_amiodarone_XLSX/24086820

الاتاحة: https://doi.org/10.3389/fphar.2023.1248882.s001
https://figshare.com/articles/dataset/DataSheet1_Integrating_distribution_kinetics_and_toxicodynamics_to_assess_repeat_dose_neurotoxicity_in_vitro_using_human_BrainSpheres_a_case_study_on_amiodarone_XLSX/24086820

المؤلفون: Adam I. Kramer, Faisal Khosa, Nicolas Murray, Ana-Maria Bilawich, Savvas Nicolaou, Tong Wu, Rawan Abu Mughli

المصدر: American Journal of Roentgenology. 217:76-82

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Acute coronary syndrome, Computed Tomography Angiography, medicine.medical_treatment, Coronary Artery Disease, Coronary Angiography, Single Center, Sensitivity and Specificity, Patient care, Time, 030218 nuclear medicine & medical imaging, Coronary artery disease, Young Adult, 03 medical and health sciences, Percutaneous Coronary Intervention, 0302 clinical medicine, medicine, Retrospective analysis, Humans, Radiology, Nuclear Medicine and imaging, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Reproducibility of Results, Percutaneous coronary intervention, General Medicine, Emergency department, Middle Aged, medicine.disease, Treatment Outcome, 030220 oncology & carcinogenesis, Conventional PCI, Radiographic Image Interpretation, Computer-Assisted, Female, Radiology, Emergency Service, Hospital, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5aa3323650ff3af03516785c8198a5
https://doi.org/10.2214/ajr.20.23402

المؤلفون: B Stadlinger, P Korn, N Tödtmann, U Eckelt, U Range, A Bürki, SJ Ferguson, I Kramer, A Kautz, M Schnabelrauch, M Kneissel, F Schlottig

المصدر: European Cells & Materials, Vol 25, Pp 326-340 (2013)

مصطلحات موضوعية: Implant, osseointegration, osteoporosis, animal model, surface coating, histomorphometry, biomechanics, Diseases of the musculoskeletal system, RC925-935, Orthopedic surgery, RD701-811

وصف الملف: electronic resource

Relation: http://www.ecmjournal.org/journal/papers/vol025/pdf/v025a23.pdf; https://doaj.org/toc/1473-2262

URL الوصول: https://doaj.org/article/730e1c0c42f54269a5688b8e6de46b28

المؤلفون: N. Accart, J. Dawson, F. Kolbinger, I. Kramer, N. Beckmann

المصدر: European Journal of Histochemistry, Vol 60, Iss 4 (2016)

مصطلحات موضوعية: Ankylosing spondylitis, histology, histochemistry, magnetic resonance imaging (MRI), micro computerized tomography (micro-CT)., Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.ejh.it/index.php/ejh/article/view/2667; https://doaj.org/toc/1121-760X; https://doaj.org/toc/2038-8306

URL الوصول: https://doaj.org/article/dc46a519a3f74353b90e44b8d614d3f9

المؤلفون: Styliani Fragki, Aldert H. Piersma, Joost Westerhout, Anne Kienhuis, Nynke I. Kramer, Marco J. Zeilmaker

المصدر: Regulatory Toxicology and Pharmacology, 136
Regulatory Toxicology and Pharmacology 136 (2022)

مصطلحات موضوعية: Generic PBK models, QSAR, Quantitative Structure-Activity Relationship, General Medicine, IndusChemFate, Toxicology, Models, Biological, Risk Assessment, TNO Model, Toxicokinetics, Kinetics, In vitro, Applicability domain, Animals, Humans, Toxicologie, QIVIVE

وصف الملف: application/octet-stream; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbfc13c06b66c471061656b9faa8f0f
https://pubmed.ncbi.nlm.nih.gov/36367522

المؤلفون: Rylan K. McCallum, Adam I. Kramer, Miles Marchand, Leo E. Akioyamen, Jacques Genest, Liam R. Brunham

المصدر: JACC: Advances. 2:100315

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8d7b06e13158fbc9953c9e2d2da4c4f5
https://doi.org/10.1016/j.jacadv.2023.100315

المؤلفون: E. Dupuy, K. A. Walker, J. Kar, C. D. Boone, C. T. McElroy, P. F. Bernath, J. R. Drummond, R. Skelton, S. D. McLeod, R. C. Hughes, C. R. Nowlan, D. G. Dufour, J. Zou, F. Nichitiu, K. Strong, P. Baron, R. M. Bevilacqua, T. Blumenstock, G. E. Bodeker, T. Borsdorff, A. E. Bourassa, H. Bovensmann, I. S. Boyd, A. Bracher, C. Brogniez, J. P. Burrows, V. Catoire, S. Ceccherini, S. Chabrillat, T. Christensen, M. T. Coffey, U. Cortesi, J. Davies, C. De Clercq, D. A. Degenstein, M. De Mazière, P. Demoulin, J. Dodion, B. Firanski, H. Fischer, G. Forbes, L. Froidevaux, D. Fussen, P. Gerard, S. Godin-Beekmann, F. Goutail, J. Granville, D. Griffith, C. S. Haley, J. W. Hannigan, M. Höpfner, J. J. Jin, A. Jones, N. B. Jones, K. Jucks, A. Kagawa, Y. Kasai, T. E. Kerzenmacher, A. Kleinböhl, A. R. Klekociuk, I. Kramer, H. Küllmann, J. Kuttippurath, E. Kyrölä, J.-C. Lambert, N. J. Livesey, E. J. Llewellyn, N. D. Lloyd, E. Mahieu, G. L. Manney, B. T. Marshall, J. C. McConnell, M. P. McCormick, I. S. McDermid, M. McHugh, C. A. McLinden, J. Mellqvist, K. Mizutani, Y. Murayama, D. P. Murtagh, H. Oelhaf, A. Parrish, S. V. Petelina, C. Piccolo, J.-P. Pommereau, C. E. Randall, C. Robert, C. Roth, M. Schneider, C. Senten, T. Steck, A. Strandberg, K. B. Strawbridge, R. Sussmann, D. P. J. Swart, D. W. Tarasick, J. R. Taylor, C. Tétard, L. W. Thomason, A. M. Thompson, M. B. Tully, J. Urban, F. Vanhellemont, C. Vigouroux, T. von Clarmann, P. von der Gathen, C. von Savigny, J. W. Waters, J. C. Witte, M. Wolff, J. M. Zawodny

المصدر: Atmospheric Chemistry and Physics, Vol 9, Iss 2, Pp 287-343 (2009)

مصطلحات موضوعية: Physics, QC1-999, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.atmos-chem-phys.net/9/287/2009/acp-9-287-2009.pdf; https://doaj.org/toc/1680-7316; https://doaj.org/toc/1680-7324

URL الوصول: https://doaj.org/article/a206d6cf20014d4f981b37fec9e12138