نتائج البحث - "Hye Jee Hahn"

1

Academic Journal

In Vitro Effect of Pitavastatin and Its Synergistic Activity with Isavuconazole against Acanthamoeba castellanii

المؤلفون: Hye Jee Hahn, Jose Ignacio Escrig, Brian Shing, Anjan Debnath

المصدر: Pathogens, Vol 9, Iss 9, p 681 (2020)

مصطلحات موضوعية: Acanthamoeba, free-living ameba, Acanthamoeba keratitis, statin, CYP51 inhibitor, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-0817/9/9/681; https://doaj.org/toc/2076-0817

URL الوصول: https://doaj.org/article/5e5cc9bacc654252a5f0f704ab666d19

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2

Academic Journal

In Vitro Evaluation of Farnesyltransferase Inhibitor and its Effect in Combination with 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor against Naegleria fowleri

المؤلفون: Hye Jee Hahn, Anjan Debnath

المصدر: Pathogens, Vol 9, Iss 9, p 689 (2020)

مصطلحات موضوعية: Naegleria fowleri, free-living amoeba, primary amoebic meningoencephalitis, lonafarnib, pitavastatin, farnesyltransferase, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2076-0817/9/9/689; https://doaj.org/toc/2076-0817

URL الوصول: https://doaj.org/article/9a73d43d57514084ac5fbea6a13336ad

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3

Academic Journal

Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.

المؤلفون: Wenxu Zhou, Anjan Debnath, Gareth Jennings, Hye Jee Hahn, Boden H Vanderloop, Minu Chaudhuri, W David Nes, Larissa M Podust

المصدر: PLoS Pathogens, Vol 14, Iss 9, p e1007245 (2018)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC6136796?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/4ddb238a37db41cba1bebae77a613d08

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4

Activity of Auranofin against Multiple Genotypes of Naegleria fowleri and Its Synergistic Effect with Amphotericin B In Vitro

المؤلفون: Jose Ignacio Escrig, Hye Jee Hahn, Anjan Debnath

المصدر: ACS Chemical Neuroscience. 11:2464-2471

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7d9524120c2b3e5eb03b5a775068357
https://doi.org/10.1021/acschemneuro.0c00165

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5

HMG-CoA Reductase Inhibitors as Drug Leads against Naegleria fowleri

المؤلفون: Ruben Abagyan, Shantanu Roy, Anjan Debnath, Ibne Karim M. Ali, Larissa M. Podust, Hye Jee Hahn

المصدر: ACS Chem Neurosci
ACS chemical neuroscience, vol 11, iss 19

مصطلحات موضوعية: Physiology, free-living ameba, Reductase, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, HMG-CoA reductase, Amphotericin B, Child, Naegleria fowleri, media_common, chemistry.chemical_classification, 0303 health sciences, Ergosterol, drug, General Medicine, Pharmaceutical Preparations, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Development of treatments and therapeutic interventions, medicine.drug, Drug, Adult, Cognitive Neuroscience, media_common.quotation_subject, primary amebic meningoencephalitis, Central Nervous System Protozoal Infections, Biology, Article, statins, Microbiology, Medicinal and Biomolecular Chemistry, 03 medical and health sciences, Rare Diseases, parasitic diseases, medicine, Humans, Pitavastatin, 030304 developmental biology, Neurosciences, Australia, Evaluation of treatments and therapeutic interventions, Cell Biology, biology.organism_classification, Orphan Drug, Good Health and Well Being, Enzyme, chemistry, biology.protein, Hydroxymethylglutaryl-CoA Reductase Inhibitors, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422e28bfac74068639b82feb3a888ad0
https://europepmc.org/articles/PMC7544672/

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6

In Vitro Effect of Pitavastatin and Its Synergistic Activity with Isavuconazole against Acanthamoeba castellanii

المؤلفون: Anjan Debnath, Hye Jee Hahn, Brian Shing, Jose Ignacio Escrig

المصدر: Pathogens, Vol 9, Iss 681, p 681 (2020)
Pathogens
Volume 9
Issue 9

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd845039a7707e70c847974354ac7cfa
https://www.mdpi.com/2076-0817/9/9/681

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7

Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity

المؤلفون: Angie M. Jarrad, Mark A. T. Blaskovich, Tomislav Karoli, Mark S. Butler, Chee Wei Ang, Nicholas P. West, Mark E. Cooper, Vicky M. Avery, Melissa Sykes, Kyra Woods, Anjan Debnath, Amy J. Jones, Hye Jee Hahn, Lendl Tan, Ruby Pelingon

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: 0301 basic medicine, Antiparasitic, medicine.drug_class, Antitubercular Agents, Drug Evaluation, Preclinical, Microbial Sensitivity Tests, Pharmacology, 01 natural sciences, Article, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Entamoeba histolytica, Drug Stability, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Nitroimidazole, Antiparasitic Agents, Bicyclic molecule, biology, 010405 organic chemistry, Chemistry, medicine.disease, biology.organism_classification, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Visceral leishmaniasis, Nitroimidazoles, Drug Design, Pretomanid, Microsomes, Liver, Molecular Medicine, Caco-2 Cells, Giardia lamblia, Delamanid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeebf31546a59be77d3cad28af05e55
https://doi.org/10.1021/acs.jmedchem.8b01578

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8

Repurposing Common Food Additives (Benzo Derivatives) As New Anti-parasitic Agents

المؤلفون: Vincent Huang, Kirkwood M. Land, Luisa Cheng, Jong Kim, Christina Tam, Hye Jee Hahn, Anjan Debnath

المصدر: Proceedings of 5th International Electronic Conference on Medicinal Chemistry.

مصطلحات موضوعية: food.ingredient, food, Traditional medicine, Chemistry, Anti parasitic, Food additive, Repurposing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ce343e30e20d820e84d454c0fcff9885
https://doi.org/10.3390/ecmc2019-06413

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9

Design, synthesis and preliminary antimicrobial evaluation of N-alkyl chain-tethered C-5 functionalized bis-isatins

المؤلفون: Trpta Bains, Luisa W. Cheng, Vipan Kumar, Nisha, Hye Jee Hahn, Christina C. Tam, Nicole Liu, Kirkwood M. Land, Amandeep Singh, Jong Kim, Anjan Debnath

المصدر: Med. Chem. Commun.. 8:1982-1992

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::72d2b3ca89eee29a866667a3cf6eb14e
https://doi.org/10.1039/c7md00434f

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10

Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri

المؤلفون: Larissa M. Podust, Wenxu Zhou, Hye Jee Hahn, Minu Chaudhuri, Anjan Debnath, Gareth K. Jennings, Boden H. Vanderloop, W. David Nes

المساهمون: Petri, William A

المصدر: PLoS Pathogens, Vol 14, Iss 9, p e1007245 (2018)
PLoS pathogens, vol 14, iss 9

مصطلحات موضوعية: 0301 basic medicine, Protozoan Proteins, Sequence Homology, Steroid Isomerases, chemistry.chemical_compound, Drug Discovery, Enzyme Inhibitors, lcsh:QH301-705.5, Naegleria fowleri, Ergosterol, biology, Chemistry, Drug discovery, Sterol homeostasis, Drug Synergism, Amino Acid, Sterols, Cholesterol, Biochemistry, 5.1 Pharmaceuticals, Medical Microbiology, Blood-Brain Barrier, lipids (amino acids, peptides, and proteins), Development of treatments and therapeutic interventions, medicine.symptom, Biotechnology, lcsh:Immunologic diseases. Allergy, 030106 microbiology, Immunology, Antiprotozoal Agents, Central Nervous System Protozoal Infections, Microbiology, Naegleria, Gas Chromatography-Mass Spectrometry, 03 medical and health sciences, Rare Diseases, Biosynthesis, Virology, parasitic diseases, Genetics, medicine, Humans, Amino Acid Sequence, Molecular Biology, Sequence Homology, Amino Acid, Neurosciences, Drug Repositioning, Methyltransferases, biology.organism_classification, Sterol, Brain Disorders, Biosynthetic Pathways, Orphan Drug, 030104 developmental biology, lcsh:Biology (General), Mechanism of action, Parasitology, lcsh:RC581-607

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f4b151402690c0fdb668f03e0fba30
https://pubmed.ncbi.nlm.nih.gov/30212566

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