المؤلفون: Shiue-Wei Lai, Chia-Yau Chang, Hwei-Jen Lee, Yeu-Chin Chen

المصدر: Thrombosis Journal, Vol 22, Iss 1, Pp 1-10 (2024)

مصطلحات موضوعية: Inherited antithrombin deficiency, Thrombosis disorder, SERPINC1, Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1477-9560

URL الوصول: https://doaj.org/article/e56ebd1058c74083ab35c8e5be166555

المؤلفون: Chien-Ming Lin, Yi-Xuan Ding, Shih-Ming Huang, Ying-Chuan Chen, Hwei-Jen Lee, Chih-Chien Sung, Shih-Hua Lin

المصدر: Frontiers in Endocrinology, Vol 15 (2024)

مصطلحات موضوعية: calcium-sensing receptor, familial hypocalciuric hypercalcemia, calcimimetics, parathyroid hormone, half-maximal effective concentration, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1291160/full; https://doaj.org/toc/1664-2392

URL الوصول: https://doaj.org/article/d9497854737749adab87e42ed63c9c01

المؤلفون: Hung-Che Lin, Hao-Ai Shui, Kuo-Yang Huang, Wei-Zhi Lin, Hsin-Yi Chang, Hwei-Jen Lee, Ying-Chih Lin, Yuahn-Sieh Huang, Guan-Ru Chen, Ya-Ting Yang, Hsiu-Lin Liu, Yi-Syuan Wu, Chia-Shiang Cheng, Ching-Lung Ko, Yu-Tien Chang, Jih-Chin Lee, Chen-Shien Lin, Chih-Hung Wang, Chi-Ming Chu

المصدر: Biology; Volume 11; Issue 8; Pages: 1210

مصطلحات موضوعية: bioinformatic, gene annotation, novel nitric oxide synthase, Trichomonas vaginalis, protein structure prediction

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/biology11081210

الاتاحة: https://doi.org/10.3390/biology11081210

المؤلفون: Min-Hua Tseng, Wen-Lang Fan, Hsuan Liu, Chia-Yu Yang, Jhao-Jhuang Ding, Hwei-Jen Lee, Shih-Ming Huang, Shih-Hua Lin, Jing-Long Huang

المصدر: Frontiers in Medicine, Vol 7 (2021)

مصطلحات موضوعية: lupus nephritis, thrombotic microangiopathy, genetic background, complement factor H, complement factor I gene, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2020.621609/full; https://doaj.org/toc/2296-858X

URL الوصول: https://doaj.org/article/07041b3c1985432f93bfc9d9a5874361

المؤلفون: Ching-Ming Lin, Jay-How Yang, Hwei-Jen Lee, Yu-Pang Lin, Li-Ping Tsai, Chih-Sin Hsu, G. W. Gant Luxton, Chih-Fen Hu

المصدر: Life, Vol 11, Iss 1230, p 1230 (2021)

مصطلحات موضوعية: Cockayne syndrome B, progeroid, ERCC6, whole exome sequencing, transcription-coupled nucleotide excision repair (TC-NER), Science

Relation: https://www.mdpi.com/2075-1729/11/11/1230; https://doaj.org/toc/2075-1729; https://doaj.org/article/2f06896b361347308d379e7f110296a8

الاتاحة: https://doi.org/10.3390/life11111230
https://doaj.org/article/2f06896b361347308d379e7f110296a8

المؤلفون: Tai-Lung Cha, Dah-Shyong Yu, Victor C. Lin, Sun-Yran Chang, Chung-Chih Lin, Ming-Rong Chen, Hui-Kuan Lin, Jar-Yi Ho, Cheng-Ping Yu, Hwei-Jen Lee, Shih-Ming Huang, Pei-Wen Hsiao, Guang-Huan Sun, Yu-Chi Chen, Sheng-Tang Wu, Shou-Hung Tang, Mei-Jen Chuang, Yi-Ta Tsai

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfe30199dba74fae83e1e2de1326c4b
https://doi.org/10.1158/0008-5472.c.6506796

المؤلفون: Tai-Lung Cha, Dah-Shyong Yu, Victor C. Lin, Sun-Yran Chang, Chung-Chih Lin, Ming-Rong Chen, Hui-Kuan Lin, Jar-Yi Ho, Cheng-Ping Yu, Hwei-Jen Lee, Shih-Ming Huang, Pei-Wen Hsiao, Guang-Huan Sun, Yu-Chi Chen, Sheng-Tang Wu, Shou-Hung Tang, Mei-Jen Chuang, Yi-Ta Tsai

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b74add71abb009c6f8329d17903ffbd
https://doi.org/10.1158/0008-5472.22405299

المؤلفون: Hwei-Jen Lee, Yung-Lung Chang, Jen-Tzu Liu, Sheng-Peng Wu, Wei-Min Huang, Chi-Ching Hwang, Chih-Wei Huang, Kai-Ling Huang

المصدر: Biochemical Journal. 478:2201-2215

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Mutant, Ligands, 010402 general chemistry, 4-Hydroxyphenylpyruvate Dioxygenase, 01 natural sciences, Biochemistry, Catalysis, Substrate Specificity, 03 medical and health sciences, Dioxygenase, Humans, Enzyme kinetics, Molecular Biology, 030304 developmental biology, Homogentisate 1,2-dioxygenase, 0303 health sciences, Chemistry, Substrate (chemistry), Cell Biology, Ligand (biochemistry), 0104 chemical sciences, Kinetics, Mutation, Helix, Mutant Proteins, 4-Hydroxyphenylpyruvate dioxygenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7347fa7d84ea971add7315a8092678d
https://doi.org/10.1042/bcj20210005

المؤلفون: Reyin Lien, Po-Jen Cheng, Jeng-Daw Tsai, Shih-Hua Lin, Wen-Lang Fan, Jhao-Jhuang Ding, Martin Konrad, Hwei-Jen Lee, Steven W. Shaw, Jen-Fu Hsu, Ya-Chung Tian, Shih-Ming Huang, Min-Hua Tseng, Tai-Wei Wu, Hui-Ping Chien, Jing-Long Huang

المصدر: Kidney International Reports

مصطلحات موضوعية: hypotension, medicine.medical_specialty, 030232 urology & nephrology, 030204 cardiovascular system & hematology, medicine.disease_cause, Loss of heterozygosity, 03 medical and health sciences, Exon, Pulmonary hypoplasia, 0302 clinical medicine, Clinical Research, Internal medicine, parasitic diseases, Renin–angiotensin system, medicine, hydrocortisone, Allele frequency, Mutation, business.industry, medicine.disease, Angiotensin II, angiotensinogen, founder effect, Endocrinology, renin, Nephrology, renal tubular dysgenesis, Anuria, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436c576798801bc70c58ef3d69c98999
https://doi.org/10.1016/j.ekir.2020.08.011

المؤلفون: Chih-Wei Huang, Hui-Chen Lin, Chi-Yuan Chou, Wei-Chuo Kao, Wei-Yuan Chou, Hwei-Jen Lee

المصدر: PLoS ONE, Vol 11, Iss 1, p e0145957 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4701392?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6f99013b4a5f47b38fed8b26b1b83e52

المؤلفون: Chi-Huei Lin, An-Ning Feng, Hwei-Jen Lee, Chih-Wei Huang, Yung-Lung Chang, Meng-Yuan Ni

المصدر: The Journal of Biochemistry. 167:315-322

مصطلحات موضوعية: Models, Molecular, Phenylpyruvic Acids, Protein Conformation, Stereochemistry, Mutant, Molecular Dynamics Simulation, 4-Hydroxyphenylpyruvate Dioxygenase, Biochemistry, Catalysis, 03 medical and health sciences, Protein Domains, Dioxygenase, Catalytic Domain, Humans, Enzyme kinetics, 4-hydroxyphenylpyruvate dioxygenase activity, Molecular Biology, 030304 developmental biology, Homogentisate 1,2-dioxygenase, 0303 health sciences, biology, Chemistry, Circular Dichroism, 030302 biochemistry & molecular biology, Wild type, Active site, Hydrogen Bonding, General Medicine, Kinetics, Mutation, biology.protein, Tyrosine, Hydrophobic and Hydrophilic Interactions, 4-Hydroxyphenylpyruvate dioxygenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69a4b7006b57cde4f36fa3a91d4ebde
https://doi.org/10.1093/jb/mvz092

المؤلفون: Jenny Carmichael, Federico Zara, Konstantinos Ampatzis, Somayeh Bakhtiari, Sherifa A. Hamed, Roman Chrast, Rolf Stucka, Juliane Müller, Gudrun Nürnberg, Nihal Olgaç Dündar, Erik-Jan Kamsteeg, Shoji Tsuji, Maja Di Rocco, Shazia Maqbool, Francisca Millan, Jonathan Baets, Tine Deconinck, Hanan E. Shamseldin, Tim M. Strom, Marcello Scala, Elham Alehabib, Cara M. Skraban, Isabella Ceccherini, Vincenzo Salpietro, Mohammed Anter Abdelhameed, Filippo M. Santorelli, Michele Iacomino, Peter De Jonghe, Yasuhiro Suzuki, Rossella Pasquariello, Anna Uhrova Meszarosova, James T Peterson, Ahmed Alfares, Yoshihisa Takiyama, Rebecca Schüle, Hossein Darvish, Yinghong Wang, Marta Rusmini, Selina Deschner, Adriana P. Rebelo, Fatima Rahman, Tobias B. Haack, Manuela Wiessner, Changlian Zhu, Matthis Synofzik, Filipa Bouçanova, Carsten Bergmann, Wolfgang Hüttel, Frederic Tran Mau-Them, Pavel Seeman, Elodie Lacaze, Andreas R. Janecke, Richard A. Lewis, Jin Yun Helen Chen, Meng-Yuan Ni, Michaela Auer-Grumbach, Andrea Català-Bordes, Ivana Ricca, Sheng Chih Jin, Dieter Gläser, Rita Horvath, Maryam Najafi, Jamileh Rezazadeh Varaghchi, Henry Houlden, Bart P.C. van de Warrenburg, Katheryn Grand, Gökhan Uyanik, Jan Senderek, Jean-Jacques Médard, Özgür Duman, Andrea Pedroni, Willem De Ridder, Reza Maroofian, Saghar Ghasemi Firouzabadi, Michael C. Kruer, H. Küpper, Emmanuelle Schmitt, Alistair T. Pagnamenta, Mary J H Willis, Kaya Bilguvar, Majid Alfadhel, Jonathan De Winter, Stephan Züchner, Saeed Al Tala, Hwei-Jen Lee, John M. Graham, Amy Goldstein, Ruben Portier, Stephanie Efthymiou, Yiran Xu, Ludger Schöls, Christian Beetz, Maria Gabriela Otero, Nicholas W. Wood, Najwa Anwar, Martin Kuchar, Fowzan S. Alkuraya, Tyler Mark Pierson, David Dredge, Nourelhoda A Haridy, Laetitia Lambert, Hiroyuki Ishiura, Peter Nürnberg, Luca Bartesaghi, Kishin Koh, Haitian Nan

المصدر: Brain

مصطلحات موضوعية: medicine.medical_specialty, business.industry, medicine, Neurology (clinical), Complicated hereditary spastic paraplegia, Original Articles, business, Dermatology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c62b3f0a5a44914619f38830ad9f5e
https://pubmed.ncbi.nlm.nih.gov/33970200

المؤلفون: Juliane S Müller, Adriana P. Rebelo, Fatima Rahman, Isabella Ceccherini, Shoji Tsuji, Pavel Seeman, Elodie Lacaze, Andreas R. Janecke, Sherifa A. Hamed, Elham Alehabib, Vincenzo Salpietro, Hossein Darvish, Sheng Chih Jin, Katheryn Grand, Gökhan Uyanik, Henry Houlden, Rolf Stucka, Ahmed Alfares, Francisca Millan, Andrea Pedroni, Hanna Küpper, Najwa Anwar, Andrea Catala Bordes, Michele Iacomino, Dieter Gläser, Tine Deconinck, Maja Di Rocco, Federico Zara, Jin Yun Helen Chen, Shazia Maqbool, Martin Kuchar, Kishin Koh, Tim M. Strom, Filippo M. Santorelli, Nicholas W. Wood, Stephanie Efthymiou, Marcello Scala, Selina Deschner, Jenny Carmichael, Cara M. Skraban, Gudrun Nürnberg, Maria Gabriela Otero, Michael C. Kruer, Hanan E. Shamseldin, Bart P.C. van de Warrenburg, Yasuhiro Suzuki, Haitian Nan, Somayeh Bakhtiari, Willem De Ridder, Roman Chrast, Ivana Ricca, Changlian Zhu, Rebecca Schüle, Jonathan Baets, Rossella Pasquariello, Peter De Jonghe, Fowzan S. Alkuraya, Nihal Olgaç Dündar, Majid Alfadhel, Yinghong Wang, Jamileh Rezazadeh Varaghchi, Tyler Mark Pierson, David Dredge, Peter Nürnberg, Marta Rusmini, Nourelhoda A Haridy, Yoshihisa Takiyama, Manuela Wiessner, Maryam Najafi, Saghar Ghasemi Firouzabadi, Matthis Synofzik, Frederic Tran Mau-Them, Christian Beetz, Konstantinos Ampatzis, James T Peterson, Emmanuelle Schmitt, Laetitia Lambert, Erik-Jan Kamsteeg, Kaya Bilguvar, Richard A. Lewis, Jonathan De Winter, Hwei-Jen Lee, Hiroyuki Ishiura, Jean-Jacques Médard, Luca Bartesaghi, Mary J H Willis, Anna Uhrova Meszarosova, Rita Horvath, Filipa Bouçanova, Carsten Bergmann, Wolfgang Hüttel, Meng-Yuan Ni, Mohammed Anter Abdelhameed, Tobias B. Haack, Jan Senderek, Özgür Duman, Alistair T. Pagnamenta, John M. Graham, Yiran Xu, Amy Goldstein, Ruben Portier, Michaela Auer-Grumbach, Ludger Schöls, Reza Maroofian, Stephan Züchner, Saeed Al Tala

المساهمون: Genomics England Research Consortium, PREPARE Network

المصدر: Brain
Brain 144(5), 1422-1434 (2021). doi:10.1093/brain/awab041
Brain, 144, 5, pp. 1422-1434
Brain, 144, 1422-1434

مصطلحات موضوعية: 0301 basic medicine, Male, Hereditary spastic paraplegia, Mitochondrial disease, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], 03 medical and health sciences, Mice, 0302 clinical medicine, genetics [Spastic Paraplegia, Hereditary], mitochondrial disorder, medicine, Missense mutation, Animals, Humans, HSP, autosomal recessive, hereditary spastic paraplegia, HPDL, genetics [Oxygenases], Spasticity, ddc:610, Spastic tetraplegia, Zebrafish, Homogentisate 1,2-dioxygenase, Genetics, Errata, business.industry, Spastic Paraplegia, Hereditary, medicine.disease, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Hallucinogen persisting perception disorder, Pedigree, Rats, 030104 developmental biology, Mutation, Oxygenases, Female, Neurology (clinical), Human medicine, medicine.symptom, business, Spastic quadriplegia, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032194096789f9a56cdf70372f329787
https://doi.org/10.1093/brain/awab041

المؤلفون: Chi-Ching Hwang, Yi-Hsun Chang, Hwei-Jen Lee, Tzu-Pin Wang, Yu-Mei Su, Hsin-Wei Chen, Po-Huang Liang

المصدر: PLoS ONE, Vol 8, Iss 5, p e63594 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23717450/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/5d21877c0bad475fb497996253eccd6d

المؤلفون: Jang-Foung Lin, Yung-Lin Sheih, Tsu-Chung Chang, Ni-Yuan Chang, Chiung-Wen Chang, Chia-Pei Shen, Hwei-Jen Lee

المصدر: PLoS ONE, Vol 8, Iss 8, p e69733 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3739788?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/70e72bca49674d9d89c13fb3d4542ee2

المؤلفون: Chih-wei Huang, J Med Sci, Hwei-jen Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jms.ndmctsgh.edu.tw/fdarticlee/2906315.pdf.

مصطلحات موضوعية: point

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.585.1358; http://jms.ndmctsgh.edu.tw/fdarticlee/2906315.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.585.1358
http://jms.ndmctsgh.edu.tw/fdarticlee/2906315.pdf

المؤلفون: Ming-Rong Chen, Hwei-Jen Lee, Dah-Shyong Yu, Jar-Yi Ho, Tai-Lung Cha, Shih-Ming Huang, Yi-Ta Tsai, Shou-Hung Tang, Yu-Chi Chen, Sun-Yran Chang, Hui Kuan Lin, Sheng-Tang Wu, Victor C. Lin, Pei-Wen Hsiao, Cheng-Ping Yu, Chung-Chih Lin, Mei-Jen Chuang, Guang-Huan Sun

المصدر: Cancer Research. 75:3568-3582

مصطلحات موضوعية: Male, Niacinamide, Sorafenib, Cancer Research, Indoles, Apoptosis, Mitochondrion, Biology, Disease-Free Survival, Gene Knockout Techniques, Mice, Phenols, Cell Line, Tumor, medicine, Animals, Humans, c-Raf, Phosphorylation, Aged, Phenylurea Compounds, Cancer, Drug Synergism, Protein phosphatase 2, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, Kidney Neoplasms, Mitochondria, Cell biology, Proto-Oncogene Proteins c-raf, Death-Associated Protein Kinases, Oncology, Cancer cell, Female, Reactive Oxygen Species, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d489a113c12018ca7f232776f5a3e76
https://doi.org/10.1158/0008-5472.can-14-3264

المؤلفون: Chih-Wei Huang, Chi-Ching Hwang, Yung-Lung Chang, Jen-Tzu Liu, Sheng-Peng Wu, Kai-Ling Huang, Wei-min Huang, Hwei-Jen Lee

المصدر: Biochemical Journal; Jun2021, Vol. 478 Issue 12, p2201-2215, 15p

مصطلحات موضوعية: NUCLEOPHILIC reactions, CARBOXYL group, THERMAL stability, CATALYSIS, HUMAN beings

المؤلفون: Shih-Ming Huang, Jing-Long Huang, Shih-Hua Lin, Chih-Jen Cheng, Hwei-Jen Lee, Fu-Sung Lo, Min-Hua Tseng

المصدر: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Mutation, Missense, lcsh:Medicine, Biology, Retinoid X receptor, Gene mutation, Calcitriol receptor, Article, 03 medical and health sciences, Transactivation, CYP24A1, Calcitriol, Internal medicine, Coactivator, medicine, Missense mutation, Humans, lcsh:Science, Child, Promoter Regions, Genetic, Vitamin D3 24-Hydroxylase, Multidisciplinary, lcsh:R, Homozygote, Alopecia, 030104 developmental biology, Endocrinology, HEK293 Cells, Nuclear receptor, Amino Acid Substitution, Receptors, Calcitriol, lcsh:Q, lipids (amino acids, peptides, and proteins), Familial Hypophosphatemic Rickets, Protein Multimerization, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4afe8e422b835ccdcf89fa563275ae
http://europepmc.org/articles/PMC5681508

المؤلفون: Tz-Chong Chou, Ching-Yu Chou, Hwei-Jen Lee, Hung Chang, Cheng-Yi Chang

المصدر: Phytomedicine : international journal of phytotherapy and phytopharmacology. 51

مصطلحات موضوعية: 0301 basic medicine, Male, Nitric Oxide Synthase Type III, Hypertension, Pulmonary, Pharmaceutical Science, Nitric Oxide Synthase Type II, Pharmacology, Peptidyl-Dipeptidase A, Pulmonary Artery, Vascular Remodeling, Lignans, Muscle hypertrophy, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Angiotensin Receptor Antagonists, Drug Discovery, Animals, Receptor, Pneumonectomy, Protein kinase B, Lung, Antihypertensive Agents, Monocrotaline, biology, Endothelin-1, Hypertrophy, Right Ventricular, Chemistry, Angiotensin II, Biphenyl Compounds, biology.organism_classification, Endothelin 1, Magnolol, Rats, Nitric oxide synthase, Magnolia officinalis, 030104 developmental biology, Complementary and alternative medicine, biology.protein, Molecular Medicine, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99848c3cb71b8ff2661eed1847d9fb7
https://pubmed.ncbi.nlm.nih.gov/31302531