المؤلفون: Amanda Van de Poël (3207963), Leticia Toledo-Sherman (1621495), Perla Breccia (1436419), Roger Cachope (6481730), Jennifer R. Bate (6481733), Ivan Angulo-Herrera (6481736), Grant Wishart (1296015), Kim L. Matthews (1436434), Sarah L. Martin (6481739), Marcus Peacock (2481088), Amy Barnard (103194), Helen C. Cox (6481742), Graham Jones (2128291), George McAllister (139252), Huw Vater (6481745), William Esmieu (6481748), Cole Clissold (10498431), Marieke Lamers (1436449), Philip Leonard (1621432), Rebecca E. Jarvis (1436422), Wesley Blackaby (6378014), Maria Eznarriaga (6481757), Ovadia Lazari (2019820), Dawn Yates (139224), Mark Rose (193952), Sung-Wook Jang (40477), Ignacio Muñoz-Sanjuan (1621456), Celia Dominguez (139255)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Ecology, Immunology, Cancer, Inorganic Chemistry, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, Vps 34 ATP-binding site, HD, pyranone-thioxanthene, Vps 34, selectivity optimization process, kinase, X-ray crystal structures, Vps 34-ATM protein chimera, brain-penetrant ataxia telangiectas., Huntington, autophagy

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Exploration_of_Selectivity_for_ATM_Inhibitors_in_Huntington_s_Disease/14340000

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00114.s001

المؤلفون: Amanda Van de Poël (3207963), Leticia Toledo-Sherman (1621495), Perla Breccia (1436419), Roger Cachope (6481730), Jennifer R. Bate (6481733), Ivan Angulo-Herrera (6481736), Grant Wishart (1296015), Kim L. Matthews (1436434), Sarah L. Martin (6481739), Marcus Peacock (2481088), Amy Barnard (103194), Helen C. Cox (6481742), Graham Jones (2128291), George McAllister (139252), Huw Vater (6481745), William Esmieu (6481748), Cole Clissold (10498431), Marieke Lamers (1436449), Philip Leonard (1621432), Rebecca E. Jarvis (1436422), Wesley Blackaby (6378014), Maria Eznarriaga (6481757), Ovadia Lazari (2019820), Dawn Yates (139224), Mark Rose (193952), Sung-Wook Jang (40477), Ignacio Muñoz-Sanjuan (1621456), Celia Dominguez (139255)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Ecology, Immunology, Cancer, Inorganic Chemistry, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, Vps 34 ATP-binding site, HD, pyranone-thioxanthene, Vps 34, selectivity optimization process, kinase, X-ray crystal structures, Vps 34-ATM protein chimera, brain-penetrant ataxia telangiectas., Huntington, autophagy

Relation: https://figshare.com/articles/dataset/Structure-Based_Exploration_of_Selectivity_for_ATM_Inhibitors_in_Huntington_s_Disease/14340003

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00114.s002