المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Reverse_transcriptase_qPCR_analysis_of_i_PINK1_i_in_LCLs_/16990626

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s003

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Age_and_sex_of_PBMC_donors_/16990629

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s004

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Characteristics_of_primary_antibodies_used_in_this_study_/16990632

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s005

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Uncropped_unadjusted_images_of_western_blots_/16990638

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s007

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Analysis_of_PINK1_expression_in_different_cell_types_/16990623

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s002

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/journal_contribution/Time_course_analysis_of_MFN_ubiquitination_in_Jurkat_cells_/16990620

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s001

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_CCCP-induced_MFN_ubiquitination_in_cultured_fibroblast_cells_/16990641

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g001

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/dataset/Calculations_for_Figs_5A_and_5D_and_6A_6C_and_6D_/16990635

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.s006

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_CCCP-induced_MFN_ubiquitination_in_Jurkat_cells_/16990644

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g002

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_CCCP-induced_MFN_ubiquitination_in_different_cell_types_/16990647

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g003

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/CCCP_induces_mitochondrial_depolarisation_in_Jurkat_and_PBMC_samples_/16990653

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g004

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_Parkin_expression_in_different_cell_types_/16990656

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g005

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_PINK1_expression_in_different_cell_types_/16990659

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g006

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Analysis_of_PINK1_Parkin_signalling_pathway_in_lymphoblastoid_cell_lines_and_CD3_CD28_activated_PBMCs_/16990665

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g008

المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable

Relation: https://figshare.com/articles/figure/Parkin_does_not_accumulate_on_CCCP-induced_depolarised_PBMC_mitochondria_/16990662

الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g007