المؤلفون: Tianlun Qiu, Huagang Luo, Wuqiao Bao

المصدر: Frontiers in Neurology, Vol 15 (2025)

مصطلحات موضوعية: acute intracranial internal carotid artery occlusion, Willis compensation, collateral circulation, circle of Willis, prognosis, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2024.1428721/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/ae7c1552dd414ed08708a5225563da94

المؤلفون: Yan Xu, Miglena Prabagar, Ku Lu, Rukiye-Nazan Eraslan, Albert Uveges, Jason Trama, Rachael Siegel, Stan Nawoschik, Michael McQueney, Grant Gallagher, Venu Bommireddy, Jim Beasley, Jane Wu, William Solvibile, Steven Paget, Daniel Miller, Brian McGuinness, Brett Marinelli, Huagang Lu, David Kaelin, Chia-Yu Huang, Audrey Hospital, David Diller, Axel Metzger

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::36fa335acea9c7eb796a7401ab35c2f6
https://doi.org/10.1021/scimeetings.1c00291

المؤلفون: David Wilson, Bindhu V. Karanam, Mona Purcell, Maria Madeira, Gary G. Chicchi, Jianming Bao, Liza Gantert, Robert J. DeVita, Huagang Lu, Wai-Si Eng, Sander G. Mills, Richard G. Ball, Andrew J. Kassick, Peter Lin, Sanjeev Kumar, Jaime Lynn Bunda, George A. Doss, Kwei-Lan C. Tsao, Jacquelyn J. Cook, Xinchun Tong, Richard Tschirret-Guth, Jinlong Jiang, Koppara Samuel, Richard Hargreaves, Hong Wang, Donald F. Hora

المصدر: Journal of Medicinal Chemistry. 56:5940-5948

مصطلحات موضوعية: Trifluoromethyl, CYP3A4, Chemistry, Stereochemistry, Glucuronidation, chemistry.chemical_compound, Drug Discovery, medicine, Molecular Medicine, Potency, NK1 receptor antagonist, Once daily dosing, Short duration, Aprepitant, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::94febe29ddadade1fbafbe0e7e0c71d3
https://doi.org/10.1021/jm400751p

المؤلفون: William A. Kinney, Julia Ma, Shuo Wu, Jinhong Chang, Ju-Tao Guo, Huagang Lu, Xuexiang Zhang, Fang Guo, Yanming Du, Zhengyin Yan, Katherine Yang, Jia Guo, Lam Patrick Y S, Qing Su, Timothy M. Block, Yu-Huan Li

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, Endoplasmic reticulum, Organic Chemistry, Prodrug, Pharmacology, Dengue virus, medicine.disease_cause, Biochemistry, In vitro, Bioavailability, 03 medical and health sciences, 030104 developmental biology, Pharmacokinetics, In vivo, Drug Discovery, biology.protein, medicine, Glucosidases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eafa3e94f6be75720f74dd0e12518b8
https://europepmc.org/articles/PMC5304290/

المؤلفون: Andrew J, Kassick, Jinlong, Jiang, Jaime, Bunda, David, Wilson, Jianming, Bao, Huagang, Lu, Peter, Lin, Richard G, Ball, George A, Doss, Xinchun, Tong, Kwei-Lan C, Tsao, Hong, Wang, Gary, Chicchi, Bindhu, Karanam, Richard, Tschirret-Guth, Koppara, Samuel, Donald F, Hora, Sanjeev, Kumar, Maria, Madeira, Waisi, Eng, Richard, Hargreaves, Mona, Purcell, Liza, Gantert, Jacquelyn, Cook, Robert J, DeVita, Sander G, Mills

المصدر: Journal of medicinal chemistry. 56(14)

مصطلحات موضوعية: Glucuronides, Neurokinin-1 Receptor Antagonists, Metabolic Clearance Rate, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Humans, Drug Interactions, Isoindoles, Substance P, Oxazoles, Peptide Fragments

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b81957365353e94734b4df68ad567f3d
https://pubmed.ncbi.nlm.nih.gov/23808489

المؤلفون: Gary G. Chicchi, Kwei-Lan C. Tsao, Huagang Lu, Xinchun Tong, Gregori J. Morriello, Robert J. DeVita, Alan Wheeldon, Emma J. Carlson, Sander G. Mills, Song Zheng, Jianming Bao, Marc M. Kurtz

المصدر: Bioorganicmedicinal chemistry letters. 20(7)

مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Indolizines, Pharmaceutical Science, Receptors, Neurokinin-1, Gerbil, Biochemistry, Pyrrolidine, chemistry.chemical_compound, Structure-Activity Relationship, Neurokinin-1 Receptor Antagonists, In vivo, Drug Discovery, Molecular Medicine, Functional activity, Animals, Humans, Receptor, Selectivity, Gerbillinae, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f528cd8177c783967c22911a6cf6d1ce
https://pubmed.ncbi.nlm.nih.gov/20188553

المؤلفون: Shigeki Nakagawa, John Rogowskyj, Xiaodong Xu, William A. Kinney, Nicolas Goossens, Takaaki Higashi, Anu Venkatesh, Yujin Hoshida, Timothy M. Block, Huagang Lu, Spiros P. Hiotis, Myron E. Schwarz, Anna P. Koh, Yanming Du, Noshena Khan, Ganesh Gunasekaran, Andrea Cuconati, Wenquan Yu

المصدر: Bioorganic & Medicinal Chemistry Letters

مصطلحات موضوعية: Carcinoma, Hepatocellular, Stereochemistry, Clinical Biochemistry, Carbonates, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Aminothiazole, Cell Line, Tumor, Drug Discovery, medicine, Humans, Prodrugs, Molecular Biology, Amination, Cell Proliferation, Chemistry, Liver Neoplasms, Organic Chemistry, Prodrug, medicine.disease, 3. Good health, Thiazoles, Liver, Cell culture, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Toxicity, Molecular Medicine, 030211 gastroenterology & hepatology, Liver cancer, Selectivity, Isopropyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1352a1d1fdaf504edf2638b3f5dd19d0