المؤلفون: Hota, Swetansu K, Rao, Kavitha S, Blair, Andrew P, Khalilimeybodi, Ali, Hu, Kevin M, Thomas, Reuben, So, Kevin, Kameswaran, Vasumathi, Xu, Jiewei, Polacco, Benjamin J, Desai, Ravi V, Chatterjee, Nilanjana, Hsu, Austin, Muncie, Jonathon M, Blotnick, Aaron M, Winchester, Sarah AB, Weinberger, Leor S, Hüttenhain, Ruth, Kathiriya, Irfan S, Krogan, Nevan J, Saucerman, Jeffrey J, Bruneau, Benoit G

المصدر: Nature. 602(7895)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Genetics, Stem Cell Research - Embryonic - Non-Human, Pediatric, Cardiovascular, Heart Disease, Stem Cell Research, 1.1 Normal biological development and functioning, Animals, Bone Morphogenetic Protein 4, Cell Differentiation, Cell Lineage, Chromatin, Chromatin Assembly and Disassembly, DNA Helicases, Embryo, Mammalian, Epigenesis, Genetic, Female, Gene Expression Regulation, Male, Mesoderm, Mice, Myocardium, Myocytes, Cardiac, Neurogenesis, Neurons, Nuclear Proteins, Octamer Transcription Factor-6, Phenotype, Repressor Proteins, Stem Cells, Time Factors, Transcription Factors, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0s20m15c
https://escholarship.org/content/qt0s20m15c/qt0s20m15c.pdf

المؤلفون: Kathiriya, Irfan S., Dominguez, Martin H., Rao, Kavitha S., Muncie-Vasic, Jonathon M., Devine, W. Patrick, Hu, Kevin M., Hota, Swetansu K., Garay, Bayardo I., Quintero, Diego, Goyal, Piyush, Matthews, Megan N., Thomas, Reuben, Sukonnik, Tatyana, Miguel-Perez, Dario, Winchester, Sarah, Brower, Emily F., Forjaz, André, Wu, Pei-Hsun, Wirtz, Denis, Kiemen, Ashley L., Bruneau, Benoit G.

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Interventricular septum (IVS), Congenital heart defect (CHD), Cardiac birth defects

وصف الملف: application/pdf

Relation: Kathiriya IS, Dominguez MH, Rao KS, et al. A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects. Preprint. bioRxiv. 2024;2024.02.05.578995. Published 2024 Mar 4. doi:10.1101/2024.02.05.578995; https://hdl.handle.net/1805/41591

الاتاحة: https://hdl.handle.net/1805/41591

المؤلفون: Kathiriya, Irfan S, Rao, Kavitha S, Iacono, Giovanni, Devine, W Patrick, Blair, Andrew P, Hota, Swetansu K, Lai, Michael H, Garay, Bayardo I, Thomas, Reuben, Gong, Henry Z, Wasson, Lauren K, Goyal, Piyush, Sukonnik, Tatyana, Hu, Kevin M, Akgun, Gunes A, Bernard, Laure D, Akerberg, Brynn N, Gu, Fei, Li, Kai, Speir, Matthew L, Haeussler, Maximilian, Pu, William T, Stuart, Joshua M, Seidman, Christine E, Seidman, JG, Heyn, Holger, Bruneau, Benoit G

المصدر: Developmental cell. 56(3)

مصطلحات موضوعية: Heart Ventricles, Myocytes, Cardiac, Animals, Humans, Mice, Heart Defects, Congenital, T-Box Domain Proteins, Cell Differentiation, Transcription, Genetic, Body Patterning, Gene Dosage, Mutation, Models, Biological, Gene Regulatory Networks, Haploinsufficiency, MEF2 Transcription Factors, cardiomyocyte differentiation, congenital heart disease, disease modeling, gene dosage, gene regulation, gene regulatory networks, haploinsufficiency, human induced pluripotent stem cells, single cell transcriptomics, transcription factor, Heart Disease - Coronary Heart Disease, Cardiovascular, Genetics, Human Genome, Stem Cell Research, Heart Disease, Congenital Structural Anomalies, Pediatric, 1.1 Normal biological development and functioning, Aetiology, 2.1 Biological and endogenous factors, Underpinning research, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0ws080nc