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1Academic Journal
المؤلفون: Halasz, Haley, Malekos, Eric, Covarrubias, Sergio, Yitiz, Samira, Montano, Christy, Sudek, Lisa, Katzman, Sol, Liu, S, Horlbeck, Max, Namvar, Leila, Weissman, Jonathan, Carpenter, Susan
المصدر: Proceedings of the National Academy of Sciences. 121(22)
مصطلحات موضوعية: CRISPRi, inflammation, long noncoding RNA, macrophage, short encoded peptide, RNA, Long Noncoding, Humans, Macrophages, Cell Differentiation, Signal Transduction, Monocytes, Inflammation, Toll-Like Receptor 4, NF-kappa B, Trans-Activators, Proto-Oncogene Proteins, CRISPR-Cas Systems, Gene Expression Regulation
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2Academic Journal
المؤلفون: Morales, Jacqueline, Allegakoen, David V, Garcia, José A, Kwong, Kristen, Sahu, Pushpendra K, Fajardo, Drew A, Pan, Yue, Horlbeck, Max A, Weissman, Jonathan S, Gustafson, W Clay, Bivona, Trever G, Sabnis, Amit J
المصدر: JCI Insight. 7(23)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Pediatric Cancer, Genetics, Cancer, Rare Diseases, Pediatric, 2.1 Biological and endogenous factors, Child, Humans, Mechanistic Target of Rapamycin Complex 1, Neoplasms, Forkhead Box Protein O1, Drug therapy, Oncology, Signal transduction, Biomedical and clinical sciences, Health sciences
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3Academic Journal
المؤلفون: Yan, Xiaowei, Stuurman, Nico, Ribeiro, Susana A, Tanenbaum, Marvin E, Horlbeck, Max A, Liem, Christina R, Jost, Marco, Weissman, Jonathan S, Vale, Ronald D
المصدر: Journal of Cell Biology. 220(2)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Human Genome, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, CRISPR-Cas Systems, Cell Line, Cell Nucleus, Cell Nucleus Size, Flow Cytometry, Genetic Testing, Green Fluorescent Proteins, Humans, Imaging, Three-Dimensional, Optics and Photonics, Phenotype, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
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4Academic Journal
المؤلفون: Le Vasseur, Maxence, Friedman, Jonathan, Jost, Marco, Xu, Jiawei, Yamada, Justin, Kampmann, Martin, Horlbeck, Max A, Salemi, Michelle R, Phinney, Brett S, Weissman, Jonathan S, Nunnari, Jodi
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Rare Diseases, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Antimycin A, CRISPR-Associated Protein 9, CRISPR-Cas Systems, Clustered Regularly Interspaced Short Palindromic Repeats, Electron Transport Complex III, Endopeptidases, Genome-Wide Association Study, Humans, K562 Cells, Mitochondria, Neoplasm Proteins, Oxidative Phosphorylation, Prohibitins, Proteolysis, Repressor Proteins, Complex III, cell biology, cytochrome c1, electron transport chain, human, mitochondria, prohibitin, protease, Biological sciences, Biomedical and clinical sciences, Health sciences
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5Academic JournalCRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
المؤلفون: Liu, S John, Malatesta, Martina, Lien, Brian V, Saha, Parna, Thombare, Shivani S, Hong, Sung Jun, Pedraza, Leslie, Koontz, Mark, Seo, Kyounghee, Horlbeck, Max A, He, Daniel, Birk, Harjus S, Jain, Miten, Olsen, Hugh E, Akeson, Mark, Weissman, Jonathan S, Monje, Michelle, Gupta, Nalin, Raleigh, David R, Ullian, Erik M, Lim, Daniel A
المصدر: Genome Biology. 21(1)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Oncology and Carcinogenesis, Rare Diseases, Radiation Oncology, Orphan Drug, Brain Cancer, Genetics, Biotechnology, Neurosciences, Cancer, Brain Disorders, 5.1 Pharmaceuticals, Adult, Astrocytes, Brain, Brain Neoplasms, CRISPR-Cas Systems, Cell Line, Tumor, Combined Modality Therapy, Glioblastoma, Humans, Oligonucleotides, Antisense, Organoids, RNA, Long Noncoding, Radiation Tolerance, CRISPRi, lncRNA, Radiation, Glioma, Cancer therapy, Environmental Sciences, Biological Sciences, Information and Computing Sciences, Bioinformatics
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6Academic Journal
المؤلفون: Jost, Marco, Santos, Daniel A, Saunders, Reuben A, Horlbeck, Max A, Hawkins, John S, Scaria, Sonia M, Norman, Thomas M, Hussmann, Jeffrey A, Liem, Christina R, Gross, Carol A, Weissman, Jonathan S
المصدر: Nature Biotechnology. 38(3)
مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Human Genome, Bioengineering, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, CRISPR-Cas Systems, Computational Biology, Deep Learning, Gene Editing, Gene Expression, Genomic Library, HeLa Cells, Humans, K562 Cells, Phenotype, RNA, Guide, CRISPR-Cas Systems, Sequence Analysis, RNA, Single-Cell Analysis, Hela Cells
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7Academic Journal
المؤلفون: Frazier, Zoë J, Kilic, Seyda, Osika, Hailey, Mo, Alisa, Quinn, Meg, Ballal, Sonia, Katz, Tamar, Shearer, A Eliot, Horlbeck, Max A, Pais, Lynn S, Dies, Kira A, O'Donnell-Luria, Anne, Kossowsky, Joe, Lipton, Jonathan O, Kleefstra, Tjitske, Srivastava, Siddharth
المصدر: Clin Genet ; ISSN:1399-0004
مصطلحات موضوعية: 9q34.3 deletion, EHMT1, Kleefstra syndrome, genotype–phenotype correlation, neurodevelopment
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8Academic Journal
المؤلفون: Bassaganyas, Laia, Popa, Stephanie J, Horlbeck, Max, Puri, Claudia, Stewart, Sarah E, Campelo, Felix, Ashok, Anupama, Butnaru, Cristian M, Brouwers, Nathalie, Heydari, Kartoosh, Ripoche, Jean, Weissman, Jonathan, Rubinsztein, David C, Schekman, Randy, Malhotra, Vivek, Moreau, Kevin, Villeneuve, Julien
المصدر: Journal of Cell Biology. 218(11)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Human Genome, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, Carrier Proteins, Cell Cycle Proteins, Cells, Cultured, Clustered Regularly Interspaced Short Palindromic Repeats, Golgi Apparatus, HEK293 Cells, HeLa Cells, Humans, Hela Cells, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
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9Academic Journal
المؤلفون: Norman, Thomas M, Horlbeck, Max A, Replogle, Joseph M, Ge, Alex Y, Xu, Albert, Jost, Marco, Gilbert, Luke A, Weissman, Jonathan S
المصدر: Science. 365(6455)
مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Cancer, Human Genome, Machine Learning and Artificial Intelligence, Genetics, Cancer Genomics, Biotechnology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Apoptosis, CRISPR-Cas Systems, Calcium-Binding Proteins, Cell Cycle Checkpoints, Cell Line, Tumor, Epistasis, Genetic, Erythroid Cells, Erythropoiesis, Female, Gene Expression Profiling, Granulocytes, Humans, Microfilament Proteins, Proto-Oncogene Proteins c-cbl, Sequence Analysis, RNA, Single-Cell Analysis, Calponins, General Science & Technology
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10Academic Journal
المؤلفون: Mendelsohn, Bryce A, Bennett, Neal K, Darch, Maxwell A, Yu, Katharine, Nguyen, Mai K, Pucciarelli, Daniela, Nelson, Maxine, Horlbeck, Max A, Gilbert, Luke A, Hyun, William, Kampmann, Martin, Nakamura, Jean L, Nakamura, Ken
المصدر: PLoS biology. 16(8)
مصطلحات موضوعية: Mitochondria, Humans, Ubiquinone, Mitochondrial Proteins, Adenosine Triphosphate, Energy Metabolism, High-Throughput Screening Assays, Single-Cell Analysis, Clustered Regularly Interspaced Short Palindromic Repeats, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Developmental Biology
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URL الوصول: https://escholarship.org/uc/item/1vp7g6cn
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11Academic Journal
المؤلفون: Horlbeck, Max A, Xu, Albert, Wang, Min, Bennett, Neal K, Park, Chong Y, Bogdanoff, Derek, Adamson, Britt, Chow, Eric D, Kampmann, Martin, Peterson, Tim R, Nakamura, Ken, Fischbach, Michael A, Weissman, Jonathan S, Gilbert, Luke A
المصدر: Cell. 174(4)
مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Cancer, 2.1 Biological and endogenous factors, Generic health relevance, Biomarkers, Cholesterol, Clustered Regularly Interspaced Short Palindromic Repeats, Epistasis, Genetic, Gene Regulatory Networks, High-Throughput Nucleotide Sequencing, Humans, Jurkat Cells, K562 Cells, Protein Interaction Mapping, CRISPR, CRISPRi, epistasis, functional genomics, genetic interactions, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
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12Academic Journal
المؤلفون: Wangensteen, Kirk J, Wang, Yue J, Dou, Zhixun, Wang, Amber W, Mosleh‐Shirazi, Elham, Horlbeck, Max A, Gilbert, Luke A, Weissman, Jonathan S, Berger, Shelley L, Kaestner, Klaus H
المصدر: Hepatology. 68(2)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Immunology, Human Genome, Cancer, Biotechnology, Digestive Diseases, Liver Disease, Genetics, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Good Health and Well Being, Animals, Blotting, Western, Carcinogenesis, Carcinoma, Hepatocellular, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Expression Regulation, Neoplastic, Genetic Testing, High-Throughput Nucleotide Sequencing, Immunohistochemistry, Liver, Liver Neoplasms, Mice, Oncogenes, RNA, Guide, CRISPR-Cas Systems, Real-Time Polymerase Chain Reaction, Transcriptional Activation, Medical Biochemistry and Metabolomics, Gastroenterology & Hepatology, Clinical sciences
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13Academic Journal
المؤلفون: Martinko, Alexander J, Truillet, Charles, Julien, Olivier, Diaz, Juan E, Horlbeck, Max A, Whiteley, Gordon, Blonder, Josip, Weissman, Jonathan S, Bandyopadhyay, Sourav, Evans, Michael J, Wells, James A
مصطلحات موضوعية: Cell Line, Tumor, Humans, Neoplasms, ras Proteins, Membrane Proteins, Antineoplastic Agents, Immunologic Factors, Antibodies, Drug Carriers, Molecular Targeted Therapy, antibody engineering, biochemistry, cancer biology, cancer target discovery, human, mouse, oncogenic RAS, Cancer, Biotechnology, 2.1 Biological and endogenous factors, Biochemistry and Cell Biology
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URL الوصول: https://escholarship.org/uc/item/69r3960v
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14Academic Journal
المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S
المصدر: Molecular Cell. 68(1)
مصطلحات موضوعية: Biological Sciences, Infectious Diseases, Biotechnology, Prevention, Genetics, Cancer, Orphan Drug, Rare Diseases, Human Genome, 5.1 Pharmaceuticals, Generic health relevance, Antineoplastic Agents, CRISPR-Cas Systems, Colchicine, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Genetic Testing, Genetic Vectors, Glycine, HeLa Cells, Humans, K562 Cells, Kinesins, Lentivirus, Microtubules, Mutation, Myelodysplastic Syndromes, RNA, Guide, CRISPR-Cas Systems, Recombinant Fusion Proteins, Small Molecule Libraries, Sulfones, Tubulin, Tubulin Modulators, Vinblastine, Hela Cells, CRISPRa, CRISPRi, chemical genetics, drug mechanism of action, drug target identification, genome-wide CRISPR screening, microtubules, rigosertib, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences
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15Academic Journal
المؤلفون: Liu, S John, Horlbeck, Max A, Cho, Seung Woo, Birk, Harjus S, Malatesta, Martina, He, Daniel, Attenello, Frank J, Villalta, Jacqueline E, Cho, Min Y, Chen, Yuwen, Mandegar, Mohammad A, Olvera, Michael P, Gilbert, Luke A, Conklin, Bruce R, Chang, Howard Y, Weissman, Jonathan S, Lim, Daniel A
المصدر: Science. 355(6320)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research - Induced Pluripotent Stem Cell, Stem Cell Research, Human Genome, Biotechnology, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Cell Growth Processes, Cell Line, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Knockdown Techniques, Gene Regulatory Networks, Genetic Loci, Genetic Testing, Genome, Human, Humans, Induced Pluripotent Stem Cells, Machine Learning, RNA Interference, RNA, Long Noncoding, Transcription, Genetic, Transcriptome, General Science & Technology
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16Academic Journal
المؤلفون: Adamson, Britt, Norman, Thomas M, Jost, Marco, Cho, Min Y, Nuñez, James K, Chen, Yuwen, Villalta, Jacqueline E, Gilbert, Luke A, Horlbeck, Max A, Hein, Marco Y, Pak, Ryan A, Gray, Andrew N, Gross, Carol A, Dixit, Atray, Parnas, Oren, Regev, Aviv, Weissman, Jonathan S
المصدر: Cell. 167(7)
مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Cancer Genomics, Human Genome, Cancer, Biotechnology, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Animals, Clustered Regularly Interspaced Short Palindromic Repeats, Endoribonucleases, Feedback, Humans, Models, Molecular, Protein Serine-Threonine Kinases, RNA, Guide, CRISPR-Cas Systems, Sequence Analysis, RNA, Single-Cell Analysis, Transcription, Genetic, Unfolded Protein Response, CRIPSRi, CRISPR, Single-cell RNA-seq, cell-to-cell heterogeneity, genome-scale screening, single-cell genomics, unfolded protein response, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
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17Academic Journal
المؤلفون: Braun, Christian J, Bruno, Peter M, Horlbeck, Max A, Gilbert, Luke A, Weissman, Jonathan S, Hemann, Michael T
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(27)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Genetics, Human Genome, 2.1 Biological and endogenous factors, Generic health relevance, Animals, Bacterial Proteins, CRISPR-Associated Protein 9, DNA Damage, DNA Modification Methylases, DNA Repair Enzymes, Dacarbazine, Drug Resistance, Neoplasm, Endonucleases, Gene Expression Regulation, Leukemic, Genetic Techniques, Leukemia, Experimental, Mice, Sequence Analysis, RNA, Temozolomide, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, cancer genetics, cancer models, cancer therapeutic resistance, gene regulation, CRISPR
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18Academic Journal
المؤلفون: Mandegar, Mohammad A, Huebsch, Nathaniel, Frolov, Ekaterina B, Shin, Edward, Truong, Annie, Olvera, Michael P, Chan, Amanda H, Miyaoka, Yuichiro, Holmes, Kristin, Spencer, C Ian, Judge, Luke M, Gordon, David E, Eskildsen, Tilde V, Villalta, Jacqueline E, Horlbeck, Max A, Gilbert, Luke A, Krogan, Nevan J, Sheikh, Søren P, Weissman, Jonathan S, Qi, Lei S, So, Po-Lin, Conklin, Bruce R
المصدر: Cell Stem Cell. 18(4)
مصطلحات موضوعية: Biological Sciences, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research - Induced Pluripotent Stem Cell, Human Genome, Regenerative Medicine, Stem Cell Research, Biotechnology, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Silencing, Humans, Induced Pluripotent Stem Cells, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
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19Academic Journal
المؤلفون: Wu, David, Poddar, Aunoy, Ninou, Elpiniki, Hwang, Elizabeth, Cole, Mitchel A., Liu, S. John, Horlbeck, Max A., Chen, Jin, Replogle, Joseph M., Carosso, Giovanni A., Eng, Nicolas W.L., Chang, Jonghoon, Shen, Yin, Weissman, Jonathan S., Lim, Daniel A.
المصدر: Cell Genomics ; volume 2, issue 11, page 100177 ; ISSN 2666-979X
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20Academic Journal
المؤلفون: Kampmann, Martin, Horlbeck, Max A, Chen, Yuwen, Tsai, Jordan C, Bassik, Michael C, Gilbert, Luke A, Villalta, Jacqueline E, Kwon, S Chul, Chang, Hyeshik, Kim, V Narry, Weissman, Jonathan S
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 112(26)
مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Biotechnology, Prevention, Human Genome, Animals, Artificial Intelligence, Genome, Humans, Mice, RNA Interference, RNA, Small Interfering, functional genomics, shRNA, genetic screen, pooled screen, microRNA
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